| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiaoqin Zhang, Yufei Mei, Yang He, Dongpi Wang, Jing Wang, Xiaojie Wei, Enlu Yang, Dongming Zhou, Haowei Shen, Guoping Peng, Qiang Shu, Xuekun Li, Benyan Luo, Yudong Zhou, Binggui Su. Ablating Adult Neural Stem Cells Improves Synaptic and Cognitive Functions in Alzheimer Models. Stem cell reports. vol 16. issue 1. 2021-06-07. PMID:33382977. |
adult neurogenesis is impaired in the hippocampus of patients with alzheimer disease (ad) as well as ad models. |
2021-06-07 |
2023-08-13 |
mouse |
| Jonathan D Cherry, Camille D Esnault, Zachary H Baucom, Yorghos Tripodis, Bertrand R Huber, Victor E Alvarez, Thor D Stein, Dennis W Dickson, Ann C McKe. Tau isoforms are differentially expressed across the hippocampus in chronic traumatic encephalopathy and Alzheimer's disease. Acta neuropathologica communications. vol 9. issue 1. 2021-06-07. PMID:33980303. |
tau isoforms are differentially expressed across the hippocampus in chronic traumatic encephalopathy and alzheimer's disease. |
2021-06-07 |
2023-08-13 |
Not clear |
| Jonathan D Cherry, Camille D Esnault, Zachary H Baucom, Yorghos Tripodis, Bertrand R Huber, Victor E Alvarez, Thor D Stein, Dennis W Dickson, Ann C McKe. Tau isoforms are differentially expressed across the hippocampus in chronic traumatic encephalopathy and Alzheimer's disease. Acta neuropathologica communications. vol 9. issue 1. 2021-06-07. PMID:33980303. |
however, the hippocampus is also heavily affected in many other tauopathies, such as alzheimer's disease (ad). |
2021-06-07 |
2023-08-13 |
Not clear |
| Jia-Yi Ynag, Jing Jiang, Hui-Ling Tian, Zi-Dong Wang, Jing-Yu Ren, Hao Liu, Zhi-Gang L. [Effect of electroacupuncture on learning-memory ability and expression of IL-1β, IL-6 and TNF-α in hippocampus and spleen in mice with Alzheimer's disease]. Zhen ci yan jiu = Acupuncture research. vol 46. issue 5. 2021-06-07. PMID:34085456. |
[effect of electroacupuncture on learning-memory ability and expression of il-1β, il-6 and tnf-α in hippocampus and spleen in mice with alzheimer's disease]. |
2021-06-07 |
2023-08-13 |
mouse |
| Jia-Yi Ynag, Jing Jiang, Hui-Ling Tian, Zi-Dong Wang, Jing-Yu Ren, Hao Liu, Zhi-Gang L. [Effect of electroacupuncture on learning-memory ability and expression of IL-1β, IL-6 and TNF-α in hippocampus and spleen in mice with Alzheimer's disease]. Zhen ci yan jiu = Acupuncture research. vol 46. issue 5. 2021-06-07. PMID:34085456. |
to explore the effect of electroacupuncture (ea) on the ability of spatial learning-memory and the expression of il-1β, il-6 and tnf-α in the hippocampus and spleen tissues and the number of hippocampal neurons and spleen lymphocytes in alzheimer's disease (ad) mice, so as to study its mechanisms underlying improvement of ad. |
2021-06-07 |
2023-08-13 |
mouse |
| Yan Wang, Wei Lv, Yueyang Li, Dandan Liu, Xiuting He, Ting Li. Ampelopsin Improves Cognitive Impairment in Alzheimer's Disease and Effects of Inflammatory Cytokines and Oxidative Stress in the Hippocampus. Current Alzheimer research. vol 17. issue 1. 2021-06-07. PMID:31797758. |
ampelopsin improves cognitive impairment in alzheimer's disease and effects of inflammatory cytokines and oxidative stress in the hippocampus. |
2021-06-07 |
2023-08-13 |
rat |
| Jing Ma, Yuan Gao, Wei Tang, Wei Huang, Yong Tan. Fluoxetine Protects against Dendritic Spine Loss in Middle-aged APPswe/PSEN1dE9 Double Transgenic Alzheimer's Disease Mice. Current Alzheimer research. vol 17. issue 1. 2021-06-07. PMID:32053075. |
studies have suggested that cognitive impairment in alzheimer's disease (ad) is associated with dendritic spine loss, especially in the hippocampus. |
2021-06-07 |
2023-08-13 |
mouse |
| Gabrielle Pfutzenreuter, Kenny Nieradka, Márcia Regina Pincerati, Ilton Santos da Silv. Intracerebroventricular streptozotocin induces behavioral impairments and increases short‑term C3 gene expression in the hippocampus of Wistar rats. Acta neurobiologiae experimentalis. vol 80. issue 2. 2021-06-07. PMID:32602856. |
the behavioral tests were followed by brain removal and hippocampal dissection for rna extraction and qrt‑pcr to assess the expression levels of 4 alzheimer's disease related genes: mapt, apoe, c3 and ps‑1. |
2021-06-07 |
2023-08-13 |
rat |
| Simon Schwab, Soroosh Afyouni, Yan Chen, Zaizhu Han, Qihao Guo, Thomas Dierks, Lars-Olof Wahlund, Matthias Griede. Functional Connectivity Alterations of the Temporal Lobe and Hippocampus in Semantic Dementia and Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 76. issue 4. 2021-06-03. PMID:32651312. |
functional connectivity alterations of the temporal lobe and hippocampus in semantic dementia and alzheimer's disease. |
2021-06-03 |
2023-08-13 |
Not clear |
| Michele Veldsman, Lisa Nobis, Fidel Alfaro-Almagro, Sanjay Manohar, Masud Husai. The human hippocampus and its subfield volumes across age, sex and APOE e4 status. Brain communications. vol 3. issue 1. 2021-06-02. PMID:33615215. |
the hippocampus has a selective vulnerability to atrophy in ageing that may be accelerated in alzheimer's disease, including in those with increased genetic risk of the disease, years before onset. |
2021-06-02 |
2023-08-13 |
human |
| Michele Veldsman, Lisa Nobis, Fidel Alfaro-Almagro, Sanjay Manohar, Masud Husai. The human hippocampus and its subfield volumes across age, sex and APOE e4 status. Brain communications. vol 3. issue 1. 2021-06-02. PMID:33615215. |
variation in global hippocampal and subfield volume associated with sex, age and apolipoprotein e e4 status has the potential to provide a sensitive biomarker of future vulnerability to alzheimer's disease. |
2021-06-02 |
2023-08-13 |
human |
| Yuriy Pomeshchik, Oxana Klementieva, Jeovanis Gil, Isak Martinsson, Marita Grønning Hansen, Tessa de Vries, Anna Sancho-Balsells, Kaspar Russ, Ekaterina Savchenko, Anna Collin, Ana Rita Vaz, Silvia Bagnoli, Benedetta Nacmias, Claire Rampon, Sandro Sorbi, Dora Brites, György Marko-Varga, Zaal Kokaia, Melinda Rezeli, Gunnar K Gouras, Laurent Roybo. Human iPSC-Derived Hippocampal Spheroids: An Innovative Tool for Stratifying Alzheimer Disease Patient-Specific Cellular Phenotypes and Developing Therapies. Stem cell reports. vol 15. issue 1. 2021-06-02. PMID:32589876. |
human ipsc-derived hippocampal spheroids: an innovative tool for stratifying alzheimer disease patient-specific cellular phenotypes and developing therapies. |
2021-06-02 |
2023-08-13 |
human |
| Yuriy Pomeshchik, Oxana Klementieva, Jeovanis Gil, Isak Martinsson, Marita Grønning Hansen, Tessa de Vries, Anna Sancho-Balsells, Kaspar Russ, Ekaterina Savchenko, Anna Collin, Ana Rita Vaz, Silvia Bagnoli, Benedetta Nacmias, Claire Rampon, Sandro Sorbi, Dora Brites, György Marko-Varga, Zaal Kokaia, Melinda Rezeli, Gunnar K Gouras, Laurent Roybo. Human iPSC-Derived Hippocampal Spheroids: An Innovative Tool for Stratifying Alzheimer Disease Patient-Specific Cellular Phenotypes and Developing Therapies. Stem cell reports. vol 15. issue 1. 2021-06-02. PMID:32589876. |
the hippocampus is important for memory formation and is severely affected in the brain with alzheimer disease (ad). |
2021-06-02 |
2023-08-13 |
human |
| Daruoosh Zare, Mohammad Amin Rajizadeh, Marzieh Maneshian, Hossein Jonaidi, Vahid Sheibani, Majid Asadi-Shekaari, Manouchehr Yousefi, Khadijeh Esmaeilpou. Inhibition of protease-activated receptor 1 (PAR1) ameliorates cognitive performance and synaptic plasticity impairments in animal model of Alzheimer's diseases. Psychopharmacology. vol 238. issue 6. 2021-06-01. PMID:33624157. |
the aim of the present study was to evaluate the effect of par1 inhibition by using sch (as an inhibitor of par1) on spatial learning, memory, and synaptic plasticity in the ca1 region of the hippocampus in rat model of alzheimer's disease. |
2021-06-01 |
2023-08-13 |
rat |
| Hannah L Chandler, Carl J Hodgetts, Xavier Caseras, Kevin Murphy, Thomas M Lancaste. Polygenic risk for Alzheimer's disease shapes hippocampal scene-selectivity. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 45. issue 7. 2021-05-27. PMID:31896120. |
polygenic risk for alzheimer's disease shapes hippocampal scene-selectivity. |
2021-05-27 |
2023-08-13 |
Not clear |
| Geraldo Busatto Filho, Fabio Luiz de Souza Duran, Paula Squarzoni, Artur Martins Novaes Coutinho, Pedro Gomes Penteado Rosa, Leticia Torralbo, Clarice Gameiro da Fonseca Pachi, Naomi Antunes da Costa, Fabio Henrique de Gobbi Porto, Cleudiana Lima Carvalho, Sonia Maria Dozzi Brucki, Ricardo Nitrini, Orestes Vicente Forlenza, Claudia da Costa Leite, Carlos Alberto Buchpiguel, Daniele de Paula Fari. Hippocampal subregional volume changes in elders classified using positron emission tomography-based Alzheimer's biomarkers of β-amyloid deposition and neurodegeneration. Journal of neuroscience research. vol 99. issue 2. 2021-05-24. PMID:33073383. |
hippocampal subregional volume changes in elders classified using positron emission tomography-based alzheimer's biomarkers of β-amyloid deposition and neurodegeneration. |
2021-05-24 |
2023-08-13 |
human |
| Geraldo Busatto Filho, Fabio Luiz de Souza Duran, Paula Squarzoni, Artur Martins Novaes Coutinho, Pedro Gomes Penteado Rosa, Leticia Torralbo, Clarice Gameiro da Fonseca Pachi, Naomi Antunes da Costa, Fabio Henrique de Gobbi Porto, Cleudiana Lima Carvalho, Sonia Maria Dozzi Brucki, Ricardo Nitrini, Orestes Vicente Forlenza, Claudia da Costa Leite, Carlos Alberto Buchpiguel, Daniele de Paula Fari. Hippocampal subregional volume changes in elders classified using positron emission tomography-based Alzheimer's biomarkers of β-amyloid deposition and neurodegeneration. Journal of neuroscience research. vol 99. issue 2. 2021-05-24. PMID:33073383. |
changes in hippocampal subfield volumes (hsv) along the alzheimer's disease (ad) continuum have been scarcely investigated to date in elderly subjects classified based on the presence of β-amyloid aggregation and signs of neurodegeneration. |
2021-05-24 |
2023-08-13 |
human |
| Guodong Liu, Chaoqiang Liu, Anqi Qi. Spatial correlation maps of the hippocampus with cerebrospinal fluid biomarkers and cognition in Alzheimer's disease: A longitudinal study. Human brain mapping. vol 42. issue 9. 2021-05-22. PMID:33739550. |
spatial correlation maps of the hippocampus with cerebrospinal fluid biomarkers and cognition in alzheimer's disease: a longitudinal study. |
2021-05-22 |
2023-08-13 |
human |
| Guodong Liu, Chaoqiang Liu, Anqi Qi. Spatial correlation maps of the hippocampus with cerebrospinal fluid biomarkers and cognition in Alzheimer's disease: A longitudinal study. Human brain mapping. vol 42. issue 9. 2021-05-22. PMID:33739550. |
this study is an observational study that takes the existing longitudinal data from alzheimer's disease neuroimaging initiative to examine the spatial correlation map of hippocampal subfield atrophy with csf biomarkers and cognitive decline in the course of ad. |
2021-05-22 |
2023-08-13 |
human |
| Hazal Haytural, Tomàs Jordà-Siquier, Bengt Winblad, Christophe Mulle, Lars O Tjernberg, Ann-Charlotte Granholm, Susanne Frykman, Gaël Barthe. Distinctive alteration of presynaptic proteins in the outer molecular layer of the dentate gyrus in Alzheimer's disease. Brain communications. vol 3. issue 2. 2021-05-22. PMID:34013204. |
here, we performed immunofluorescence labelling of different synaptic proteins in fixed and paraffin-embedded human hippocampal sections and report reduced levels of several presynaptic proteins of the neurotransmitter release machinery (complexin-1, syntaxin-1a, synaptotagmin-1 and synaptogyrin-1) in alzheimer's disease cases. |
2021-05-22 |
2023-08-13 |
human |