All Relations between Alzheimer Disease and hippocampus

Publication Sentence Publish Date Extraction Date Species
Michael Popiolek, Yael Mandelblat-Cerf, Damon Young, Jonathan Garst-Orozco, Susan M Lotarski, Eda Stark, Melissa Kramer, Christopher R Butler, Rouba Koza. In Vivo Modulation of Hippocampal Excitability by M4 Muscarinic Acetylcholine Receptor Activator: Implications for Treatment of Alzheimer's Disease and Schizophrenic Patients. ACS chemical neuroscience. vol 10. issue 3. 2020-03-05. PMID:30335349. abnormal hippocampal activity has been linked to impaired cognitive performance in alzheimer's disease and schizophrenia, leading to a hypothesis that normalization of this activity may be therapeutically beneficial. 2020-03-05 2023-08-13 Not clear
B A Ardekani, S A Hadid, E Blessing, A H Bachma. Sexual Dimorphism and Hemispheric Asymmetry of Hippocampal Volumetric Integrity in Normal Aging and Alzheimer Disease. AJNR. American journal of neuroradiology. vol 40. issue 2. 2020-03-02. PMID:30655257. sexual dimorphism and hemispheric asymmetry of hippocampal volumetric integrity in normal aging and alzheimer disease. 2020-03-02 2023-08-13 Not clear
B A Ardekani, S A Hadid, E Blessing, A H Bachma. Sexual Dimorphism and Hemispheric Asymmetry of Hippocampal Volumetric Integrity in Normal Aging and Alzheimer Disease. AJNR. American journal of neuroradiology. vol 40. issue 2. 2020-03-02. PMID:30655257. asymmetric atrophy of the hippocampus is an important clinical finding in normal aging and alzheimer disease. 2020-03-02 2023-08-13 Not clear
E Orta-Salazar, A I Feria-Velasco, S Díaz-Cintr. Primary motor cortex alterations in Alzheimer disease: A study in the 3xTg-AD model. Neurologia (Barcelona, Spain). vol 34. issue 7. 2020-03-02. PMID:28433262. in humans and animal models, alzheimer disease (ad) is characterised by accumulation of amyloid-β peptide (aβ) and hyperphosphorylated tau protein, neuronal degeneration, and astrocytic gliosis, especially in vulnerable brain regions (hippocampus and cortex). 2020-03-02 2023-08-13 mouse
Francesca Rocchio, Laura Tapella, Marcello Manfredi, Mariangela Chisari, Francesca Ronco, Federico Alessandro Ruffinatti, Eleonora Conte, Pier Luigi Canonico, Maria Angela Sortino, Mariagrazia Grilli, Emilio Marengo, Armando A Genazzani, Dmitry Li. Gene expression, proteome and calcium signaling alterations in immortalized hippocampal astrocytes from an Alzheimer's disease mouse model. Cell death & disease. vol 10. issue 1. 2020-02-26. PMID:30631041. gene expression, proteome and calcium signaling alterations in immortalized hippocampal astrocytes from an alzheimer's disease mouse model. 2020-02-26 2023-08-13 mouse
Francesca Rocchio, Laura Tapella, Marcello Manfredi, Mariangela Chisari, Francesca Ronco, Federico Alessandro Ruffinatti, Eleonora Conte, Pier Luigi Canonico, Maria Angela Sortino, Mariagrazia Grilli, Emilio Marengo, Armando A Genazzani, Dmitry Li. Gene expression, proteome and calcium signaling alterations in immortalized hippocampal astrocytes from an Alzheimer's disease mouse model. Cell death & disease. vol 10. issue 1. 2020-02-26. PMID:30631041. evidence is rapidly growing regarding a role of astroglial cells in the pathogenesis of alzheimer's disease (ad), and the hippocampus is one of the important brain regions affected in ad. 2020-02-26 2023-08-13 mouse
Kun Zhang, Bin Li, Peifang Li, Xiaoli Yang, Huixian Cui, Xiaoyun Li. Cell-based immunofluorescence assay for screening the neurogenesis potential of new drugs in adult hippocampal neural progenitor cells. Acta neurobiologiae experimentalis. vol 79. issue 3. 2020-02-18. PMID:31587022. preclinical studies have suggested that increased adult neurogenesis in the hippocampus might have potential therapeutic effects for alzheimer's disease and depression; therefore, it is a target for the treatment of some brain diseases. 2020-02-18 2023-08-13 Not clear
Muaz Belviranlı, Nilsel Okuda. Voluntary, involuntary and forced exercises almost equally reverse behavioral impairment by regulating hippocampal neurotrophic factors and oxidative stress in experimental Alzheimer's disease model. Behavioural brain research. vol 364. 2020-02-13. PMID:30790584. voluntary, involuntary and forced exercises almost equally reverse behavioral impairment by regulating hippocampal neurotrophic factors and oxidative stress in experimental alzheimer's disease model. 2020-02-13 2023-08-13 rat
Muaz Belviranlı, Nilsel Okuda. Voluntary, involuntary and forced exercises almost equally reverse behavioral impairment by regulating hippocampal neurotrophic factors and oxidative stress in experimental Alzheimer's disease model. Behavioural brain research. vol 364. 2020-02-13. PMID:30790584. the purpose of this study was to compare the neuroprotective effects of voluntary, involuntary, and forced exercise trainings on behavioral impairment as well as hippocampal alzheimer's disease (ad) pathology and oxidative stress markers, and levels of neurotrophic factors in the rat model of ad. 2020-02-13 2023-08-13 rat
Raphaël Sivera, Hervé Delingette, Marco Lorenzi, Xavier Pennec, Nicholas Ayach. A model of brain morphological changes related to aging and Alzheimer's disease from cross-sectional assessments. NeuroImage. vol 198. 2020-02-12. PMID:31121298. in the model, the morphological changes associated with normal aging are mainly found around the ventricles, while the alzheimer's disease specific changes are located in the temporal lobe and the hippocampal area. 2020-02-12 2023-08-13 human
Katharina Schmidt, Bilal Bari, Martina Ralle, Clorissa Washington-Hughes, Abigael Muchenditsi, Evan Maxey, Svetlana Lutsenk. Localization of the Locus Coeruleus in the Mouse Brain. Journal of visualized experiments : JoVE. issue 145. 2020-01-31. PMID:30907876. structural or functional abnormalities of lc impact several brain regions including cortex, hippocampus, and cerebellum and may contribute to depression, bipolar disorder, anxiety, as well as parkinson disease and alzheimer disease. 2020-01-31 2023-08-13 mouse
Wen-Dan Yang, Wan-Qing Guo, Chang-Hui Qian, Qian Xu, Xue-Hua Zheng, Wei-Guo Don. [Effect of early intervention of electroacupuncture on learning-memory ability and level of hippocampal phosphorylated Tau protein in SAMP8 mice]. Zhongguo zhen jiu = Chinese acupuncture & moxibustion. vol 40. issue 1. 2020-01-29. PMID:31930902. to explore the effect of early intervention electroacupuncture (ea) at "baihui" (gv 20), "dazhui" (gv 14) and "shenshu" (bl 23) on the learning-memory ability and the expression of phosphorylated tau protein in the hippocampus of samp8 mice, so as to provide reference for the intervening period of ea for alzheimer's disease (ad). 2020-01-29 2023-08-13 mouse
Vincent Planche, Pierrick Coupé, Catherine Helmer, Mélanie Le Goff, Helene Amieva, François Tison, Jean-François Dartigues, Gwénaëlle Cathelin. Evolution of brain atrophy subtypes during aging predicts long-term cognitive decline and future Alzheimer's clinical syndrome. Neurobiology of aging. vol 79. 2020-01-27. PMID:31026619. in cox proportional-hazards models, "hippocampal predominant atrophy" was associated with an increased risk of developing alzheimer's clinical syndrome over time (hazard ratio = 5.73; 95% ci 2.71-12.15), independently of age and apoe4 genotype, the 2 other significant predictive factors. 2020-01-27 2023-08-13 human
Vincent Planche, Pierrick Coupé, Catherine Helmer, Mélanie Le Goff, Helene Amieva, François Tison, Jean-François Dartigues, Gwénaëlle Cathelin. Evolution of brain atrophy subtypes during aging predicts long-term cognitive decline and future Alzheimer's clinical syndrome. Neurobiology of aging. vol 79. 2020-01-27. PMID:31026619. as a possible surrogate of confined tauopathy and early alzheimer's disease pathology, future studies should consider the definition of "hippocampal predominant atrophy" based on hippocampal-to-cortical volume ratio evolution rather than hippocampal volume alone. 2020-01-27 2023-08-13 human
Li Wang, Yansong Zheng, Xiaoxiao Gao, Yingchun Liu, Xiaoqing Yo. Retinoid X receptor ligand regulates RXRα/Nur77-dependent apoptosis via modulating its nuclear export and mitochondrial targeting. International journal of clinical and experimental pathology. vol 10. issue 11. 2020-01-26. PMID:31966420. thus, we detected the changes of the expression and subcellular localization of rxrα/nur77 and the apoptotic rate of neuroblastoma cells, sh-sy5y cells and nerve cells in c57bl/6 mouse hippocampus in alzheimer's disease pathologic condition, and investigated the effect of rxrα exporting inhibition caused by 9-cis-ra on the apoptosis of neurons. 2020-01-26 2023-08-13 mouse
Ruoxuan Cui, Manhua Li. Hippocampus Analysis by Combination of 3-D DenseNet and Shapes for Alzheimer's Disease Diagnosis. IEEE journal of biomedical and health informatics. vol 23. issue 5. 2020-01-17. PMID:30475734. hippocampus analysis by combination of 3-d densenet and shapes for alzheimer's disease diagnosis. 2020-01-17 2023-08-13 human
Ruoxuan Cui, Manhua Li. Hippocampus Analysis by Combination of 3-D DenseNet and Shapes for Alzheimer's Disease Diagnosis. IEEE journal of biomedical and health informatics. vol 23. issue 5. 2020-01-17. PMID:30475734. hippocampus is one of the first involved regions in alzheimer's disease (ad) and mild cognitive impairment (mci), a prodromal stage of ad. 2020-01-17 2023-08-13 human
Natalie M Zahr, Kilian M Pohl, Manojkumar Saranathan, Edith V Sullivan, Adolf Pfefferbau. Hippocampal subfield CA2+3 exhibits accelerated aging in Alcohol Use Disorder: A preliminary study. NeuroImage. Clinical. vol 22. 2020-01-17. PMID:30904825. for example, damage to hippocampal subfield cornu ammonis 1 (ca1) is often reported in alzheimer's disease (ad), whereas deficits in ca4/dentate gyrus are described in response to stress and trauma. 2020-01-17 2023-08-13 human
Sujin Kim, Yunkwon Nam, Yu-On Jeong, Hyun Ha Park, Seong-Kyung Lee, Soo Jung Shin, Haram Jung, Byeong-Hyeon Kim, Sang Bum Hong, Yong Ho Park, Jihee Kim, Jaemin Yu, Doo-Han Yoo, Sun-Hyun Park, Seong Gak Jeon, Minho Moo. Topographical Visualization of the Reciprocal Projection between the Medial Septum and the Hippocampus in the 5XFAD Mouse Model of Alzheimer's Disease. International journal of molecular sciences. vol 20. issue 16. 2020-01-17. PMID:31426329. topographical visualization of the reciprocal projection between the medial septum and the hippocampus in the 5xfad mouse model of alzheimer's disease. 2020-01-17 2023-08-13 mouse
Masayuki Shintaku, Hiroyuki Yabata, Eri Tanaka, Masanori Shiohara, Ryoji Kushim. Amyotrophic lateral sclerosis with appearance of many skein-like inclusions in anterior horn cells. International journal of clinical and experimental pathology. vol 12. issue 11. 2020-01-17. PMID:31933814. an alzheimer type tau-pathology was found mainly in the hippocampus (braak stage iii), and many argyrophilic grains were distributed in the limbic area. 2020-01-17 2023-08-13 Not clear