| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiaomeng Han, Peter H Li, Shuohong Wang, Morgan Sanchez, Sneha Aggarwal, Tim Blakely, Richard Schalek, Yaron Meirovitch, Zudi Lin, Daniel Berger, Yuelong Wu, Fatima Aly, Sylvie Bay, Benoît Delatour, Pierre LaFaye, Hanspeter Pfister, Donglai Wei, Viren Jain, Hidde Ploegh, Jeff Lichtma. A large-scale volumetric correlated light and electron microscopy study localizes Alzheimer's disease-related molecules in the hippocampus. bioRxiv : the preprint server for biology. 2023-11-14. PMID:37961104. |
a large-scale volumetric correlated light and electron microscopy study localizes alzheimer's disease-related molecules in the hippocampus. |
2023-11-14 |
2023-11-20 |
mouse |
| Xiaomeng Han, Peter H Li, Shuohong Wang, Morgan Sanchez, Sneha Aggarwal, Tim Blakely, Richard Schalek, Yaron Meirovitch, Zudi Lin, Daniel Berger, Yuelong Wu, Fatima Aly, Sylvie Bay, Benoît Delatour, Pierre LaFaye, Hanspeter Pfister, Donglai Wei, Viren Jain, Hidde Ploegh, Jeff Lichtma. A large-scale volumetric correlated light and electron microscopy study localizes Alzheimer's disease-related molecules in the hippocampus. bioRxiv : the preprint server for biology. 2023-11-14. PMID:37961104. |
three molecules (ptau, aβ, and a marker for activated microglia (cd11b)) were labeled without the need for detergents by three nanobody probes in a sample of the hippocampus of the 3xtg alzheimer's disease model mouse. |
2023-11-14 |
2023-11-20 |
mouse |
| Kristian F Odfalk, Jessica L Wickline, Sabrina Smith, Radek Dobrowolski, Sarah C Hop. Hippocampal TMEM55B overexpression in the 5XFAD mouse model of Alzheimer's disease. Hippocampus. 2023-11-14. PMID:37961834. |
hippocampal tmem55b overexpression in the 5xfad mouse model of alzheimer's disease. |
2023-11-14 |
2023-11-20 |
mouse |
| Chooza Moon, Karin F Hoth, Yelena Perkounkova, Meina Zhang, Jihye Lee, Maria Hein, Lauren Hopkins, Vincent Magnotta, Helen J Burges. Circadian timing, melatonin and hippocampal volume in later-life adults. Journal of sleep research. 2023-11-08. PMID:37940373. |
hippocampal atrophy is a prominent neurodegenerative feature of alzheimer's disease and related dementias. |
2023-11-08 |
2023-11-20 |
Not clear |
| Joyce Bosmans, Hanne Gommeren, Peter Zu Eulenburg, Annick Gilles, Griet Mertens, Angelique Van Ombergen, Patrick Cras, Sebastiaan Engelborghs, Vincent Van Rompae. Is vestibular function related to human hippocampal volume? Journal of vestibular research : equilibrium & orientation. 2023-11-06. PMID:37927291. |
as hippocampal atrophy is an important biomarker of alzheimer's disease, exploring vestibular dysfunction as a risk factor for dementia and its role in hippocampal atrophy is of interest. |
2023-11-06 |
2023-11-08 |
human |
| Adriana M Zago, Fabiano B Carvalho, Francine L Rahmeier, Marta Santin, Giuliano R Guimarães, Jessié M Gutierres, Marilda da C Fernande. Exendin-4 Prevents Memory Loss and Neuronal Death in Rats with Sporadic Alzheimer-Like Disease. Molecular neurobiology. 2023-11-03. PMID:37919602. |
this study investigated the neuroprotective effects of exendin-4 (exe-4), an analog of the glucagon-like peptide 1 receptor (glp-1r) on memory and on the neuronal populations that constitute the hippocampus of rats submitted to a sporadic dementia of alzheimer's type (sdat). |
2023-11-03 |
2023-11-08 |
rat |
| Xin Tang, Ellen Walter, Eric Wohleb, Yanbo Fan, Chenran Wan. ATG5 (autophagy related 5) in microglia controls hippocampal neurogenesis in Alzheimer disease. Autophagy. 2023-11-02. PMID:37915255. |
atg5 (autophagy related 5) in microglia controls hippocampal neurogenesis in alzheimer disease. |
2023-11-02 |
2023-11-08 |
Not clear |
| Yeongae Lee, Yeon-Joo Ju, Min Sung Gee, Seung Ho Jeon, Namkwon Kim, Taeyoung Koo, Jong Kil Le. Survivin enhances hippocampal neurogenesis and cognitive function in Alzheimer's disease mouse model. CNS neuroscience & therapeutics. 2023-10-31. PMID:37904343. |
survivin enhances hippocampal neurogenesis and cognitive function in alzheimer's disease mouse model. |
2023-10-31 |
2023-11-08 |
mouse |
| Jia-Ni Li, Shao-Wu Zhang, Yan-Rui Qiang, Qin-Yi Zho. A novel cross-layer dual encoding-shared decoding network framework with spatial self-attention mechanism for hippocampus segmentation. Computers in biology and medicine. vol 167. 2023-10-26. PMID:37883852. |
accurate segmentation of the hippocampus from the brain magnetic resonance images (mris) is a crucial task in the neuroimaging research, since its structural integrity is strongly related to several neurodegenerative disorders, such as alzheimer's disease (ad). |
2023-10-26 |
2023-11-08 |
human |
| Ashok Iyaswamy, Abhimanyu Thakur, Xin-Jie Guan, Senthilkumar Krishnamoorthi, Tsz Yan Fung, Kejia Lu, Isha Gaurav, Zhijun Yang, Cheng-Fu Su, Kwok-Fai Lau, Kui Zhang, Roy Chun-Laam Ng, Qizhou Lian, King-Ho Cheung, Keqiang Ye, Huanhuan Joyce Chen, Min L. Fe65-engineered neuronal exosomes encapsulating corynoxine-B ameliorate cognition and pathology of Alzheimer's disease. Signal transduction and targeted therapy. vol 8. issue 1. 2023-10-24. PMID:37867176. |
alzheimer's disease (ad) is a neurodegenerative disorder characterized by the predominant impairment of neurons in the hippocampus and the formation of amyloid plaques, hyperphosphorylated tau protein, and neurofibrillary tangles in the brain. |
2023-10-24 |
2023-11-08 |
mouse |
| Seyed Ahmad Hashemi, Zahra Ghadimi, Hadi Ghaedi, Ayoub Hashem. The effect of eight weeks of aerobic training with vitamin C on the expression pathway of antioxidants in the hippocampus tissue of TMT induced Alzheimer's disease rats. Brain research. 2023-10-23. PMID:37871672. |
the effect of eight weeks of aerobic training with vitamin c on the expression pathway of antioxidants in the hippocampus tissue of tmt induced alzheimer's disease rats. |
2023-10-23 |
2023-11-08 |
rat |
| Seyed Ahmad Hashemi, Zahra Ghadimi, Hadi Ghaedi, Ayoub Hashem. The effect of eight weeks of aerobic training with vitamin C on the expression pathway of antioxidants in the hippocampus tissue of TMT induced Alzheimer's disease rats. Brain research. 2023-10-23. PMID:37871672. |
thus present study aimed to investigate the effect of eight weeks of aerobic training (at) with vitamin c (vc) on the expression pathway of antioxidants in the hippocampus tissue of trimethyltin chloride (tmt) induced alzheimer's disease rats. |
2023-10-23 |
2023-11-08 |
rat |
| Min Lang, Samantha Colby, Christian Ashby-Padial, Monika Bapna, Camilo Jaimes, Sandra P Rincon, Karen Buc. An imaging review of the hippocampus and its common pathologies. Journal of neuroimaging : official journal of the American Society of Neuroimaging. 2023-10-23. PMID:37872430. |
the review explores neuroimaging findings related to hippocampal variants (incomplete hippocampal inversion, sulcal remnant and choroidal fissure cysts), and pathologies of neoplastic (astrocytoma and glioma, ganglioglioma, dysembryoplastic neuroepithelial tumor, multinodular and vacuolating neuronal tumor, and metastasis), epileptic (mesial temporal sclerosis and focal cortical dysplasia), neurodegenerative (alzheimer's disease, progressive primary aphasia, and frontotemporal dementia), infectious (herpes simplex virus and limbic encephalitis), vascular (ischemic stroke, arteriovenous malformation, and cerebral cavernous malformations), and toxic-metabolic (transient global amnesia and opioid-associated amnestic syndrome) etiologies. |
2023-10-23 |
2023-11-08 |
Not clear |
| Kayo Yukawa, Satomi Yamamoto-Mcguire, Louis Cafaro, Christine Hong, Fredrik Kamme, Tsuneya Ikezu, Seiko Ikez. Antisense oligonucleotide-based targeting of Tau-tubulin kinase 1 prevents hippocampal accumulation of phosphorylated tau in PS19 tauopathy mice. Acta neuropathologica communications. vol 11. issue 1. 2023-10-20. PMID:37853497. |
tau tubulin kinase-1 (ttbk1), a neuron-specific tau kinase, is highly expressed in the entorhinal cortex and hippocampal regions, where early tau pathology evolves in alzheimer's disease (ad). |
2023-10-20 |
2023-11-08 |
mouse |
| R M Aljarar. Neuroprotective effects of a combination of Boswellia papyrifera and Syzygium aromaticum on AlCl3 induced Alzheimer's disease in male albino rat. Brazilian journal of biology = Revista brasleira de biologia. vol 83. 2023-10-20. PMID:37851769. |
alzheimer's disease (ad) is the most common neurodegenerative disease characterized by hippocampal, and cortical neuron deterioration, oxidative stress, and severe cognitive dysfunction. |
2023-10-20 |
2023-11-08 |
rat |
| Stefanie Grabrucker, Moira Marizzoni, Edina Silajdžić, Nicola Lopizzo, Elisa Mombelli, Sarah Nicolas, Sebastian Dohm-Hansen, Catia Scassellati, Davide Vito Moretti, Melissa Rosa, Karina Hoffmann, John F Cryan, Olivia F O'Leary, Jane A English, Aonghus Lavelle, Cora O'Neill, Sandrine Thuret, Annamaria Cattaneo, Yvonne M Nola. Microbiota from Alzheimer's patients induce deficits in cognition and hippocampal neurogenesis. Brain : a journal of neurology. 2023-10-18. PMID:37849234. |
microbiota from alzheimer's patients induce deficits in cognition and hippocampal neurogenesis. |
2023-10-18 |
2023-11-08 |
human |
| Stefanie Grabrucker, Moira Marizzoni, Edina Silajdžić, Nicola Lopizzo, Elisa Mombelli, Sarah Nicolas, Sebastian Dohm-Hansen, Catia Scassellati, Davide Vito Moretti, Melissa Rosa, Karina Hoffmann, John F Cryan, Olivia F O'Leary, Jane A English, Aonghus Lavelle, Cora O'Neill, Sandrine Thuret, Annamaria Cattaneo, Yvonne M Nola. Microbiota from Alzheimer's patients induce deficits in cognition and hippocampal neurogenesis. Brain : a journal of neurology. 2023-10-18. PMID:37849234. |
we found impairments in behaviours reliant on adult hippocampal neurogenesis, an essential process for certain memory functions and mood, resulting from alzheimer's patient transplants. |
2023-10-18 |
2023-11-08 |
human |
| Stefanie Grabrucker, Moira Marizzoni, Edina Silajdžić, Nicola Lopizzo, Elisa Mombelli, Sarah Nicolas, Sebastian Dohm-Hansen, Catia Scassellati, Davide Vito Moretti, Melissa Rosa, Karina Hoffmann, John F Cryan, Olivia F O'Leary, Jane A English, Aonghus Lavelle, Cora O'Neill, Sandrine Thuret, Annamaria Cattaneo, Yvonne M Nola. Microbiota from Alzheimer's patients induce deficits in cognition and hippocampal neurogenesis. Brain : a journal of neurology. 2023-10-18. PMID:37849234. |
as hippocampal neurogenesis cannot be measured in living humans but is modulated by the circulatory systemic environment, we assessed the impact of the alzheimer's systemic environment on proxy neurogenesis readouts. |
2023-10-18 |
2023-11-08 |
human |
| Stefanie Grabrucker, Moira Marizzoni, Edina Silajdžić, Nicola Lopizzo, Elisa Mombelli, Sarah Nicolas, Sebastian Dohm-Hansen, Catia Scassellati, Davide Vito Moretti, Melissa Rosa, Karina Hoffmann, John F Cryan, Olivia F O'Leary, Jane A English, Aonghus Lavelle, Cora O'Neill, Sandrine Thuret, Annamaria Cattaneo, Yvonne M Nola. Microbiota from Alzheimer's patients induce deficits in cognition and hippocampal neurogenesis. Brain : a journal of neurology. 2023-10-18. PMID:37849234. |
our findings reveal for the first time, that alzheimer's symptoms can be transferred to a healthy young organism via the gut microbiota, confirming a causal role of gut microbiota in alzheimer's disease, and highlight hippocampal neurogenesis as a converging central cellular process regulating systemic circulatory and gut-mediated factors in alzheimer's. |
2023-10-18 |
2023-11-08 |
human |
| Melissa Hernández-Frausto, Olesia M Bilash, Arjun V Masurkar, Jayeeta Bas. Local and long-range GABAergic circuits in hippocampal area CA1 and their link to Alzheimer's disease. Frontiers in neural circuits. vol 17. 2023-10-16. PMID:37841892. |
local and long-range gabaergic circuits in hippocampal area ca1 and their link to alzheimer's disease. |
2023-10-16 |
2023-11-08 |
Not clear |