| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nan Xu, Ang-Di Li, Li-Li Ji, Yao Ye, Zhen-Yu Wang, Lei Ton. miR-132 regulates the expression of synaptic proteins in APP/PS1 transgenic mice through C1q. European journal of histochemistry : EJH. vol 63. issue 2. 2019-05-28. PMID:31060348. |
cognitive impairment in alzheimer's disease (ad) is usually accompanied by synaptic loss in both the hippocampus and neocortex. |
2019-05-28 |
2023-08-13 |
mouse |
| Sunmin Park, Da Sol Kim, Suna Kang, Hyun Jin Ki. The combination of luteolin and l-theanine improved Alzheimer disease-like symptoms by potentiating hippocampal insulin signaling and decreasing neuroinflammation and norepinephrine degradation in amyloid-β-infused rats. Nutrition research (New York, N.Y.). vol 60. 2019-05-24. PMID:30527255. |
the combination of luteolin and l-theanine improved alzheimer disease-like symptoms by potentiating hippocampal insulin signaling and decreasing neuroinflammation and norepinephrine degradation in amyloid-β-infused rats. |
2019-05-24 |
2023-08-13 |
rat |
| Sunmin Park, Da Sol Kim, Suna Kang, Hyun Jin Ki. The combination of luteolin and l-theanine improved Alzheimer disease-like symptoms by potentiating hippocampal insulin signaling and decreasing neuroinflammation and norepinephrine degradation in amyloid-β-infused rats. Nutrition research (New York, N.Y.). vol 60. 2019-05-24. PMID:30527255. |
the combination of luteolin and l-theanine prevented alzheimer disease-like symptom, possibly by improving hippocampal insulin signaling, norepinephrine metabolisms, and decreasing neuroinflammation. |
2019-05-24 |
2023-08-13 |
rat |
| Pouneh Shahmohamady, Akram Eidi, Pejman Mortazavi, Negar Panahi, Dariush Minai-Tehran. Effect of sinapic acid on memory deficits and neuronal degeneration induced by intracerebroventricular administration of streptozotocin in rats. Polish journal of pathology : official journal of the Polish Society of Pathologists. vol 69. issue 3. 2019-05-22. PMID:30509053. |
histopathological examination showed that sinapic acid reduced cell loss in the cerebral cortex and hippocampus in alzheimer's rats. |
2019-05-22 |
2023-08-13 |
rat |
| Nina Schultz, Elin Byman, Malin Wennströ. Levels of retinal IAPP are altered in Alzheimer's disease patients and correlate with vascular changes and hippocampal IAPP levels. Neurobiology of aging. vol 69. 2019-05-21. PMID:29864717. |
levels of retinal iapp are altered in alzheimer's disease patients and correlate with vascular changes and hippocampal iapp levels. |
2019-05-21 |
2023-08-13 |
Not clear |
| A Kodam, D Ourdev, M Maulik, J Hariharakrishnan, M Banerjee, Y Wang, S Ka. A role for astrocyte-derived amyloid β peptides in the degeneration of neurons in an animal model of temporal lobe epilepsy. Brain pathology (Zurich, Switzerland). vol 29. issue 1. 2019-05-20. PMID:29665128. |
since amyloid-β (aβ) peptides, which are critical in the development of alzheimer's disease, can mediate toxicity by activating glutamatergic nmda receptors, it is likely that the enhanced glutamatergic transmission that renders hippocampal neurons vulnerable to kainic acid treatment may involve aβ peptides. |
2019-05-20 |
2023-08-13 |
human |
| Michael S Bienkowski, Ian Bowman, Monica Y Song, Lin Gou, Tyler Ard, Kaelan Cotter, Muye Zhu, Nora L Benavidez, Seita Yamashita, Jaspar Abu-Jaber, Sana Azam, Darrick Lo, Nicholas N Foster, Houri Hintiryan, Hong-Wei Don. Integration of gene expression and brain-wide connectivity reveals the multiscale organization of mouse hippocampal networks. Nature neuroscience. vol 21. issue 11. 2019-05-16. PMID:30297807. |
understanding the organization of the hippocampus is fundamental to understanding brain function related to learning, memory, emotions, and diseases such as alzheimer's disease. |
2019-05-16 |
2023-08-13 |
mouse |
| Henna Konttinen, Irina Gureviciene, Minna Oksanen, Alexandra Grubman, Sanna Loppi, Mikko T Huuskonen, Paula Korhonen, Riikka Lampinen, Meike Keuters, Irina Belaya, Heikki Tanila, Katja M Kanninen, Gundars Goldsteins, Gary Landreth, Jari Koistinaho, Tarja Mal. PPARβ/δ-agonist GW0742 ameliorates dysfunction in fatty acid oxidation in PSEN1ΔE9 astrocytes. Glia. vol 67. issue 1. 2019-05-15. PMID:30453390. |
defective fatty acid oxidation and mitochondrial dysfunctions correlate with hippocampal neurodegeneration and memory deficits in alzheimer's disease (ad), but it is unclear whether energy metabolism can be targeted to prevent or treat the disease. |
2019-05-15 |
2023-08-13 |
mouse |
| Bo-Wen Wu, Mi-Shan Wu, Jin-Dong Gu. Effects of microRNA-10a on synapse remodeling in hippocampal neurons and neuronal cell proliferation and apoptosis through the BDNF-TrkB signaling pathway in a rat model of Alzheimer's disease. Journal of cellular physiology. vol 233. issue 7. 2019-05-14. PMID:29215712. |
effects of microrna-10a on synapse remodeling in hippocampal neurons and neuronal cell proliferation and apoptosis through the bdnf-trkb signaling pathway in a rat model of alzheimer's disease. |
2019-05-14 |
2023-08-13 |
rat |
| Ni Gao, Li-Xin Tao, Jian Huang, Feng Zhang, Xia Li, Finbarr O'Sullivan, Si-Peng Chen, Si-Jia Tian, Gehendra Mahara, Yan-Xia Luo, Qi Gao, Xiang-Tong Liu, Wei Wang, Zhi-Gang Liang, Xiu-Hua Gu. Contourlet-based hippocampal magnetic resonance imaging texture features for multivariant classification and prediction of Alzheimer's disease. Metabolic brain disease. vol 33. issue 6. 2019-05-13. PMID:30178281. |
contourlet-based hippocampal magnetic resonance imaging texture features for multivariant classification and prediction of alzheimer's disease. |
2019-05-13 |
2023-08-13 |
human |
| Ni Gao, Li-Xin Tao, Jian Huang, Feng Zhang, Xia Li, Finbarr O'Sullivan, Si-Peng Chen, Si-Jia Tian, Gehendra Mahara, Yan-Xia Luo, Qi Gao, Xiang-Tong Liu, Wei Wang, Zhi-Gang Liang, Xiu-Hua Gu. Contourlet-based hippocampal magnetic resonance imaging texture features for multivariant classification and prediction of Alzheimer's disease. Metabolic brain disease. vol 33. issue 6. 2019-05-13. PMID:30178281. |
the study is aimed to assess whether the addition of contourlet-based hippocampal magnetic resonance imaging (mri) texture features to multivariant models improves the classification of alzheimer's disease (ad) and the prediction of mild cognitive impairment (mci) conversion, and to evaluate whether gaussian process (gp) and partial least squares (pls) are feasible in developing multivariant models in this context. |
2019-05-13 |
2023-08-13 |
human |
| Elena P Moreno-Jiménez, Miguel Flor-García, Julia Terreros-Roncal, Alberto Rábano, Fabio Cafini, Noemí Pallas-Bazarra, Jesús Ávila, María Llorens-Martí. Adult hippocampal neurogenesis is abundant in neurologically healthy subjects and drops sharply in patients with Alzheimer's disease. Nature medicine. vol 25. issue 4. 2019-05-10. PMID:30911133. |
adult hippocampal neurogenesis is abundant in neurologically healthy subjects and drops sharply in patients with alzheimer's disease. |
2019-05-10 |
2023-08-13 |
human |
| Elena P Moreno-Jiménez, Miguel Flor-García, Julia Terreros-Roncal, Alberto Rábano, Fabio Cafini, Noemí Pallas-Bazarra, Jesús Ávila, María Llorens-Martí. Adult hippocampal neurogenesis is abundant in neurologically healthy subjects and drops sharply in patients with Alzheimer's disease. Nature medicine. vol 25. issue 4. 2019-05-10. PMID:30911133. |
the hippocampus is one of the most affected areas in alzheimer's disease (ad) |
2019-05-10 |
2023-08-13 |
human |
| Cai-Feng Zhu, Li-da Zhang, Xiao-Ge Song, Jun Yang, Hong-Ping Pan, Cheng-Gong He, Kun Yang, Xiao-Feng Qin, Wan-Li Zh. [Moxibustion improves learning-memory ability by promoting cellular autophagy and regulating autophagy-related proteins in hippocampus and cerebral cortex in APP/PS1 transgenic Alzheimer's disease mice]. Zhen ci yan jiu = Acupuncture research. vol 44. issue 4. 2019-05-09. PMID:31056874. |
[moxibustion improves learning-memory ability by promoting cellular autophagy and regulating autophagy-related proteins in hippocampus and cerebral cortex in app/ps1 transgenic alzheimer's disease mice]. |
2019-05-09 |
2023-08-13 |
mouse |
| Cai-Feng Zhu, Li-da Zhang, Xiao-Ge Song, Jun Yang, Hong-Ping Pan, Cheng-Gong He, Kun Yang, Xiao-Feng Qin, Wan-Li Zh. [Moxibustion improves learning-memory ability by promoting cellular autophagy and regulating autophagy-related proteins in hippocampus and cerebral cortex in APP/PS1 transgenic Alzheimer's disease mice]. Zhen ci yan jiu = Acupuncture research. vol 44. issue 4. 2019-05-09. PMID:31056874. |
to observe the effect of moxibustion of acupoints of the governor vessel on the levels of cellular autophagy, β amyloid protein (aβ) immunoactivity, and expression of lc3-Ⅰ， lc3-Ⅱ， p62 and p-p70s6k proteins in the hippocampal tissue of appswe/ps1de9 (app/ps1) double-transgenic alzheimer's disease (ad) mice, so as to reveal its underlying mechanisms in improving ad. |
2019-05-09 |
2023-08-13 |
mouse |
| Blathnaid Hughes, Caroline E Herro. Cannabidiol Reverses Deficits in Hippocampal LTP in a Model of Alzheimer's Disease. Neurochemical research. vol 44. issue 3. 2019-05-07. PMID:29574668. |
cannabidiol reverses deficits in hippocampal ltp in a model of alzheimer's disease. |
2019-05-07 |
2023-08-13 |
Not clear |
| Zhiren Wang, Jinhui Hu, Xiaoping Yang, Xing Feng, Xingshu Li, Ling Huang, Albert S C Cha. Design, Synthesis, and Evaluation of Orally Bioavailable Quinoline-Indole Derivatives as Innovative Multitarget-Directed Ligands: Promotion of Cell Proliferation in the Adult Murine Hippocampus for the Treatment of Alzheimer's Disease. Journal of medicinal chemistry. vol 61. issue 5. 2019-05-03. PMID:29420891. |
design, synthesis, and evaluation of orally bioavailable quinoline-indole derivatives as innovative multitarget-directed ligands: promotion of cell proliferation in the adult murine hippocampus for the treatment of alzheimer's disease. |
2019-05-03 |
2023-08-13 |
mouse |
| Hyun-Sik Yang, Lei Yu, Charles C White, Lori B Chibnik, Jasmeer P Chhatwal, Reisa A Sperling, David A Bennett, Julie A Schneider, Philip L De Jage. Evaluation of TDP-43 proteinopathy and hippocampal sclerosis in relation to APOE ε4 haplotype status: a community-based cohort study. The Lancet. Neurology. vol 17. issue 9. 2019-05-02. PMID:30093249. |
transactive response dna-binding protein of 43 kda (tdp-43) proteinopathy in older adults frequently coexists with alzheimer's disease pathology and hippocampal sclerosis. |
2019-05-02 |
2023-08-13 |
Not clear |
| Do Won Hwang, Yoori Choi, Dohyun Kim, Hye Yoon Park, Kyu Wan Kim, Mee Young Kim, Chul-Kee Park, Dong Soo Le. Graphene oxide-quenching-based fluorescence in situ hybridization (G-FISH) to detect RNA in tissue: Simple and fast tissue RNA diagnostics. Nanomedicine : nanotechnology, biology, and medicine. vol 16. 2019-04-29. PMID:30594658. |
using a fluorophore-labeled peptide nucleic acid (pna) attached to go, the endogenous long noncoding rna bc1, the constitutive protein β-actin mrna, and mir-124a and mir-21 could be detected in the cytoplasm of a normal mouse brain, primary cultured hippocampal neurons, an alzheimer's disease model mouse brain, and glioblastoma multiforme tumor tissues, respectively. |
2019-04-29 |
2023-08-13 |
mouse |
| Jing Liu, Yan-Jun Du, Qing-Lian Zhou, Guo-Jie Su. [Acupuncture plus moxibustion intervention improves learning-memory ability by suppressing hippocampal JAK2/STAT3 signaling in Alzheimer's rats]. Zhen ci yan jiu = Acupuncture research. vol 44. issue 2. 2019-04-25. PMID:30945481. |
[acupuncture plus moxibustion intervention improves learning-memory ability by suppressing hippocampal jak2/stat3 signaling in alzheimer's rats]. |
2019-04-25 |
2023-08-13 |
rat |