| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rachelle Balez, Claire H Stevens, Kerstin Lenk, Kuldip Sidhu, Greg Sutherland, Lezanne Oo. Increased neuronal nitric oxide synthase in Alzheimer's disease mediates spontaneous calcium signalling and divergent glutamatergic calcium responses. Antioxidants & redox signaling. 2024-02-01. PMID:38299492. |
nitrosative stress is a feature of alzheimer's disease, however the underlying cause(s) driving nitrosative stress and the impact of nitric oxide (no) on neuronal function in alzheimer's disease is still largely unknown. |
2024-02-01 |
2024-02-03 |
Not clear |
| Haitao Ding, Li Luo, Liping Su, Junyang Chen, Yunkun Li, Lei Hu, Kui Luo, Xiaohe Tia. Gasotransmitter nitric oxide imaging in Alzheimer's disease and glioblastoma with diamino-cyclic-metalloiridium phosphorescence probes. Biosensors & bioelectronics. vol 247. 2023-12-25. PMID:38145594. |
gasotransmitter nitric oxide imaging in alzheimer's disease and glioblastoma with diamino-cyclic-metalloiridium phosphorescence probes. |
2023-12-25 |
2023-12-28 |
mouse |
| Angelo Zinellu, Sara Tommasi, Stefania Sedda, Arduino A Mangon. Circulating arginine metabolites in Alzheimer's disease and vascular dementia: a systematic review and meta-analysis. Ageing research reviews. 2023-11-25. PMID:38007048. |
alterations in nitric oxide (no) synthesis have been reported in alzheimer's disease and vascular dementia. |
2023-11-25 |
2023-11-28 |
Not clear |
| Samira Geravand, Manizheh Karami, Hedayat Sahraei, Fardin Rahim. Protective effects of L-arginine on Alzheimer's disease: Modulating hippocampal nitric oxide levels and memory deficits in aluminum chloride-induced rat model. European journal of pharmacology. 2023-09-03. PMID:37660966. |
protective effects of l-arginine on alzheimer's disease: modulating hippocampal nitric oxide levels and memory deficits in aluminum chloride-induced rat model. |
2023-09-03 |
2023-09-07 |
rat |
| Qingshuang Xu, Yutao Zhang, Mingming Zhu, Chenxu Yan, Wenle Mao, Wei-Hong Zhu, Zhiqian Gu. Bent-to-planar Si-rhodamines: a distinct rehybridization lights up NIR-II fluorescence for tracking nitric oxide in the Alzheimer's disease brain. Chemical science. vol 14. issue 15. 2023-04-17. PMID:37063795. |
bent-to-planar si-rhodamines: a distinct rehybridization lights up nir-ii fluorescence for tracking nitric oxide in the alzheimer's disease brain. |
2023-04-17 |
2023-08-14 |
Not clear |
| Lucia Scipioni, Daniel Tortolani, Francesca Ciaramellano, Federico Fanti, Thais Gazzi, Manuel Sergi, Marc Nazaré, Sergio Oddi, Mauro Maccarron. Aβ Chronic Exposure Promotes an Activation State of Microglia through Endocannabinoid Signalling Imbalance. International journal of molecular sciences. vol 24. issue 7. 2023-04-13. PMID:37047663. |
dysfunctional phenotype of microglia, the primary brain immune cells, may aggravate alzheimer's disease (ad) pathogenesis by releasing proinflammatory factors, such as nitric oxide (no). |
2023-04-13 |
2023-08-14 |
Not clear |
| Ali Azargoonjahrom. Dual role of nitric oxide in Alzheimer's Disease. Nitric oxide : biology and chemistry. 2023-04-05. PMID:37019299. |
dual role of nitric oxide in alzheimer's disease. |
2023-04-05 |
2023-08-14 |
Not clear |
| Ali Azargoonjahrom. Dual role of nitric oxide in Alzheimer's Disease. Nitric oxide : biology and chemistry. 2023-04-05. PMID:37019299. |
nitric oxide (no), an enzymatic product of nitric oxide synthase (nos), has been associated with a variety of neurological diseases such as alzheimer's disease (ad). |
2023-04-05 |
2023-08-14 |
Not clear |
| Paulina Cieślik, Magdalena Borska, Joanna Monika Wierońsk. A Comparative Study of the Impact of NO-Related Agents on MK-801- or Scopolamine-Induced Cognitive Impairments in the Morris Water Maze. Brain sciences. vol 13. issue 3. 2023-03-29. PMID:36979220. |
learning and memory deficits accompany numerous brain dysfunctions, including schizophrenia and alzheimer's disease (ad), and many studies point to the role of nitric oxide (no) in these processes. |
2023-03-29 |
2023-08-14 |
mouse |
| Swarupa Pahan, Sumita Raha, Sridevi Dasarathi, Kalipada Paha. Cinnamein Inhibits the Induction of Nitric Oxide and Proinflammatory Cytokines in Macrophages, Microglia and Astrocytes. Journal of clinical & experimental immunology. vol 8. issue 1. 2023-02-27. PMID:36848307. |
), and nitric oxide (no) plays an important role in the pathogenesis of several autoimmune, inflammatory as well as neurodegenerative disorders like rheumatoid arthritis, multiple sclerosis, alzheimer's disease, parkinson's disease, huntington's disease, etc. |
2023-02-27 |
2023-08-14 |
mouse |
| Harikesh Dubey, Anamika Dubey, Kavita Gulati, Arunabha Ra. s-Nitrosoglutathione modulates HDAC2 and BDNF levels in the brain and improves cognitive deficits in experimental model of Alzheimer`s disease in rats. The International journal of neuroscience. 2022-11-21. PMID:36408590. |
the present study evaluated the effects of the nitric oxide (no) mimetics, l-arginine and the nitrosothiol no donor, s-nitrosoglutathione (gsno), on memory and brain hdac2 levels in experimental animal model of sporadic alzheimer`s disease (sad). |
2022-11-21 |
2023-08-14 |
rat |
| Wenpeng Song, Yiming Yuan, Xiaohui Tan, Yangyang Gu, Jianyu Zeng, Weidong Song, Zhongcheng Xin, Dong Fang, Ruili Gua. Icariside II induces rapid phosphorylation of endothelial nitric oxide synthase via multiple signaling pathways. PeerJ. vol 10. 2022-10-31. PMID:36312762. |
phosphorylation of enos plays an important role in the synthesis of nitric oxide in endothelial cells, which is closely related to erectile dysfunction, atherosclerosis, alzheimer's disease, and other diseases. |
2022-10-31 |
2023-08-14 |
human |
| Md Noushad Javed, Faheem Hyder Pottoo, Mohd Javed Naim, Pooja A Chawl. Recent Advancements in CNS Acting Drugs: A Step Towards End of Illness. CNS & neurological disorders drug targets. vol 21. issue 10. 2022-09-05. PMID:36062857. |
progressive degeneration in the morphology and functions of neuronal cells leads to multifactorial pathogenesis conditions of oxidative stress, mitochondrial dysfunction, excitotoxicity, nitric oxide toxicity, and neuro-inflammation to mediate heterogeneous types of neurodegenerative diseases, such as epilepsy, alzheimer's (ad) and parkinson's (pd), more prominently among aging populations. |
2022-09-05 |
2023-08-14 |
Not clear |
| Sujata Thakur, Rishika Dhapola, Phulen Sarma, Bikash Medhi, Dibbanti HariKrishna Redd. Neuroinflammation in Alzheimer's Disease: Current Progress in Molecular Signaling and Therapeutics. Inflammation. 2022-08-20. PMID:35986874. |
numerous pathways like nfκb, p38 mapk, akt/mtor, caspase, nitric oxide, and cox are involved in triggering brain immune cells like astrocytes and microglia to secrete inflammatory cytokines such as tumor necrosis factor, interleukins, and chemokines and participate in alzheimer's disease pathology. |
2022-08-20 |
2023-08-14 |
Not clear |
| Brice Ayissi Owona, Frederic N Njayou, Pierre Mkounga, Paul F Moundip. In silico pharmacology. vol 10. issue 1. 2022-07-08. PMID:35800001. |
overproduction of nitric oxide (no) and many other pro-inflammatory mediators are responsible for many pathological disorders in humans, including alzheimer's disease (ad). |
2022-07-08 |
2023-08-14 |
Not clear |
| Kang Lu, Yu Wang, Hao Zhang, Cuiqing Tian, Wenxiang Wang, Tian Yang, Baiwen Qi, Song W. Rational Design of a Theranostic Agent Triggered by Endogenous Nitric Oxide in a Cellular Model of Alzheimer's Disease. Journal of medicinal chemistry. 2022-06-22. PMID:35729801. |
rational design of a theranostic agent triggered by endogenous nitric oxide in a cellular model of alzheimer's disease. |
2022-06-22 |
2023-08-14 |
Not clear |
| Kang Lu, Yu Wang, Hao Zhang, Cuiqing Tian, Wenxiang Wang, Tian Yang, Baiwen Qi, Song W. Rational Design of a Theranostic Agent Triggered by Endogenous Nitric Oxide in a Cellular Model of Alzheimer's Disease. Journal of medicinal chemistry. 2022-06-22. PMID:35729801. |
oxidative damage caused by upregulated nitric oxide (no) plays an important role in the pathogenesis of alzheimer's disease (ad). |
2022-06-22 |
2023-08-14 |
Not clear |
| Manizheh Karami, Samira Geravand, Mahnaz Rahimpou. Protective Effect of L-Arginine in an Animal Model of Alzheimer's Disease Induced by Intra-Hippocampal Injection of AlCl3. Neurology India. vol 70. issue 2. 2022-05-09. PMID:35532618. |
we investigated the protective effect of l-arginine, a precursor of nitric oxide (no), on memory retrieval in an alzheimer's animal model induced by alcl3 at intra-hippocampal ca1 using a seeking behavior practice. |
2022-05-09 |
2023-08-13 |
Not clear |
| Ki-Ryeong Kim, Eun-Jung Cho, Jae-Won Eom, Sang-Seok Oh, Tomohiro Nakamura, Chang-Ki Oh, Stuart A Lipton, Yang-Hee Ki. S-Nitrosylation of cathepsin B affects autophagic flux and accumulation of protein aggregates in neurodegenerative disorders. Cell death and differentiation. 2022-04-25. PMID:35462559. |
here, we report that nitric oxide (no)-related species can contribute to alzheimer's disease (ad) by s-nitrosylating the lysosomal protease cathepsin b (forming sno-ctsb), thereby inhibiting ctsb activity. |
2022-04-25 |
2023-08-13 |
mouse |
| Manish Kumar Tripathi, Maryam Kartawy, Shelly Ginzburg, Haitham Ama. Arsenic alters nitric oxide signaling similar to autism spectrum disorder and Alzheimer's disease-associated mutations. Translational psychiatry. vol 12. issue 1. 2022-03-30. PMID:35351881. |
arsenic alters nitric oxide signaling similar to autism spectrum disorder and alzheimer's disease-associated mutations. |
2022-03-30 |
2023-08-13 |
mouse |