| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shreaya Chakroborty, Joyce Kim, Corinne Schneider, Anthony R West, Grace E Stutzman. Nitric oxide signaling is recruited as a compensatory mechanism for sustaining synaptic plasticity in Alzheimer's disease mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 17. 2015-07-21. PMID:25926464. |
nitric oxide signaling is recruited as a compensatory mechanism for sustaining synaptic plasticity in alzheimer's disease mice. |
2015-07-21 |
2023-08-13 |
mouse |
| Mourad Belkhelfa, Hayet Rafa, Oussama Medjeber, Amina Arroul-Lammali, Nassima Behairi, Myriam Abada-Bendib, Mohamed Makrelouf, Soreya Belarbi, Ahmed Nacer Masmoudi, Meriem Tazir, Chafia Touil-Boukoff. IFN-γ and TNF-α are involved during Alzheimer disease progression and correlate with nitric oxide production: a study in Algerian patients. Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research. vol 34. issue 11. 2015-07-20. PMID:24831467. |
ifn-γ and tnf-α are involved during alzheimer disease progression and correlate with nitric oxide production: a study in algerian patients. |
2015-07-20 |
2023-08-13 |
Not clear |
| Yao Hu, Dong-Ya Zh. Hippocampus and nitric oxide. Vitamins and hormones. vol 96. 2015-04-13. PMID:25189386. |
based on its significant roles in neural plasticity, nitric oxide is involved in a number of central nervous diseases, such as ischemia, depression, anxiety, and alzheimer's disease. |
2015-04-13 |
2023-08-13 |
Not clear |
| Diana Cifuentes, Marine Poittevin, Ekrem Dere, Dong Broquères-You, Philippe Bonnin, Joëlle Benessiano, Marc Pocard, Jean Mariani, Nathalie Kubis, Tatyana Merkulova-Rainon, Bernard I Lév. Hypertension accelerates the progression of Alzheimer-like pathology in a mouse model of the disease. Hypertension (Dallas, Tex. : 1979). vol 65. issue 1. 2015-02-25. PMID:25331846. |
our results indicate that hypertension accelerates the development of alzheimer disease-related structural and functional alterations, partially through cerebral vasculature impairment and reduced nitric oxide production. |
2015-02-25 |
2023-08-13 |
mouse |
| Feng Jin, Qi-Hai Gong, Ya-Sha Xu, Li-Na Wang, Hai Jin, Fei Li, Li-Sheng Li, Yue-Ming Ma, Jing-Shan Sh. Icariin, a phosphodiesterase-5 inhibitor, improves learning and memory in APP/PS1 transgenic mice by stimulation of NO/cGMP signalling. The international journal of neuropsychopharmacology. vol 17. issue 6. 2015-01-22. PMID:24513083. |
phosphodiesterase-5 (pde5) inhibitors are predominantly used in the treatment of erectile dysfunction, and have been recently shown to have a potential therapeutic effect for the treatment of alzheimer's disease (ad) through stimulation of nitric oxide (no)/cyclic guanosine monophosphate (cgmp) signalling by elevating cgmp, which is a secondary messenger involved in processes of neuroplasticity. |
2015-01-22 |
2023-08-12 |
mouse |
| Susan A Austin, Anantha V Santhanam, David J Hinton, Doo-Sup Choi, Zvonimir S Katusi. Endothelial nitric oxide deficiency promotes Alzheimer's disease pathology. Journal of neurochemistry. vol 127. issue 5. 2014-05-12. PMID:23745722. |
endothelial nitric oxide deficiency promotes alzheimer's disease pathology. |
2014-05-12 |
2023-08-12 |
mouse |
| Qin Zhihu. Modulating nitric oxide signaling in the CNS for Alzheimer's disease therapy. Future medicinal chemistry. vol 5. issue 12. 2014-02-19. PMID:23919554. |
modulating nitric oxide signaling in the cns for alzheimer's disease therapy. |
2014-02-19 |
2023-08-12 |
Not clear |
| Erdinç Dursun, Duygu Gezen-Ak, Selma Yilmaze. A new mechanism for amyloid-β induction of iNOS: vitamin D-VDR pathway disruption. Journal of Alzheimer's disease : JAD. vol 36. issue 3. 2014-02-17. PMID:23624519. |
the inflammatory process in alzheimer's disease (ad) has been suggested to include oxidative and nitrosative damage caused by elevated levels of nitric oxide (no) and inducible nitric oxide synthase (inos). |
2014-02-17 |
2023-08-12 |
Not clear |
| Noboru Toda, Tomio Okamur. Cerebral blood flow regulation by nitric oxide in Alzheimer's disease. Journal of Alzheimer's disease : JAD. vol 32. issue 3. 2013-09-04. PMID:22810094. |
cerebral blood flow regulation by nitric oxide in alzheimer's disease. |
2013-09-04 |
2023-08-12 |
Not clear |
| Noboru Toda, Tomio Okamur. Cerebral blood flow regulation by nitric oxide in Alzheimer's disease. Journal of Alzheimer's disease : JAD. vol 32. issue 3. 2013-09-04. PMID:22810094. |
cerebral hypoperfusion due to impaired bioavailability of nitric oxide (no) synthesized by endothelial nitric oxide synthase and neuronal nitric oxide synthase leads to cognitive decline and neurodegeneration in alzheimer's disease (ad). |
2013-09-04 |
2023-08-12 |
Not clear |
| Ke-Wu Zeng, Ming-Bo Zhao, Zhi-Zhong Ma, Yong Jiang, Peng-Fei T. Protosappanin A inhibits oxidative and nitrative stress via interfering the interaction of transmembrane protein CD14 with Toll-like receptor-4 in lipopolysaccharide-induced BV-2 microglia. International immunopharmacology. vol 14. issue 4. 2013-06-04. PMID:23000519. |
during inflammation-mediated neurodegenerative diseases, including alzheimer's disease and parkinson's disease, reactive oxygen species (ros) and nitric oxide (no) are produced by activated microglia, further inducing increased neuronal injury in the brain. |
2013-06-04 |
2023-08-12 |
Not clear |
| Raffaella Siciliano, Eugenio Barone, Vittorio Calabrese, Vincenzo Rispoli, D Allan Butterfield, Cesare Mancus. Experimental research on nitric oxide and the therapy of Alzheimer disease: a challenging bridge. CNS & neurological disorders drug targets. vol 10. issue 7. 2013-01-21. PMID:21999733. |
experimental research on nitric oxide and the therapy of alzheimer disease: a challenging bridge. |
2013-01-21 |
2023-08-12 |
human |
| Hui Liu, Jun-pao Chen, Wan-qin Zhan. [Inducible nitric oxide synthase induces beta-amyloid neurotoxicity in vivo]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. vol 18. issue 4. 2012-12-03. PMID:21174802. |
to investigate the causative role of nitric oxide synthase (nos) and nitric oxide (no) in neurotoxicity of beta-amyloid (abeta) and the pathogenesis of alzheimer's disease (ad). |
2012-12-03 |
2023-08-12 |
Not clear |
| Rony Panarsky, Lisandro Luques, Marta Weinstoc. Anti-inflammatory effects of ladostigil and its metabolites in aged rat brain and in microglial cells. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. vol 7. issue 2. 2012-09-24. PMID:22454040. |
impaired mitochondrial function accompanied by microglial activation and the release of nitric oxide (no) and pro-inflammatory cytokines has been reported in alzheimer's disease, its prodromal phase of mild cognitive impairment (mci) and in aged rats. |
2012-09-24 |
2023-08-12 |
mouse |
| Jens Schmidt, Konstanze Barthel, Jana Zschüntzsch, Ingrid E Muth, Emily J Swindle, Anja Hombach, Stephan Sehmisch, Arne Wrede, Fred Lühder, Ralf Gold, Marinos C Dalaka. Nitric oxide stress in sporadic inclusion body myositis muscle fibres: inhibition of inducible nitric oxide synthase prevents interleukin-1β-induced accumulation of β-amyloid and cell death. Brain : a journal of neurology. vol 135. issue Pt 4. 2012-06-08. PMID:22436237. |
in alzheimer's dementia, accumulation of β-amyloid has been shown to be associated with upregulation of nitric oxide. |
2012-06-08 |
2023-08-12 |
human |
| David Vauzour, Ana Rodriguez-Mateos, Giulia Corona, Maria Jose Oruna-Concha, Jeremy P E Spence. Polyphenols and human health: prevention of disease and mechanisms of action. Nutrients. vol 2. issue 11. 2012-05-14. PMID:22254000. |
for example, their ability to activate erk in neurons leads to a promotion of neuronal survival and cognitive enhancements, both of which influence the progression of alzheimer's disease, whilst erk activation by polyphenols in vascular endothelial cells influences nitric oxide production, blood pressure and ultimately cvd risk. |
2012-05-14 |
2023-08-12 |
human |
| Jeong-Ho Park, Boe-Hyun Kim, Seok-Joo Park, Jae-Kwang Jin, Yong-Chul Jeon, Guang Y Wen, Hae-Young Shin, Richard I Carp, Yong-Sun Ki. Association of endothelial nitric oxide synthase and mitochondrial dysfunction in the hippocampus of scrapie-infected mice. Hippocampus. vol 21. issue 3. 2012-04-02. PMID:20082297. |
the elevation of nitric oxide (no) within the central nervous system (cns) is known to be associated with the pathogenesis of neurodegenerative diseases such as hiv-associated dementia (had), brain ischemia, parkinson's disease, and alzheimer's disease. |
2012-04-02 |
2023-08-12 |
mouse |
| Thomas W Miller, Jeff S Isenberg, Hubert B Shih, Yichen Wang, David D Robert. Amyloid-β inhibits No-cGMP signaling in a CD36- and CD47-dependent manner. PloS one. vol 5. issue 12. 2011-07-05. PMID:21203512. |
combined with the pleiotropic effects of inhibiting free fatty acid transport via cd36, these data provides a molecular mechanism through which amyloid-β can contribute to the nitric oxide signaling deficiencies associated with alzheimer's disease. |
2011-07-05 |
2023-08-12 |
Not clear |
| Leandro T Oliveira, Paulo Roberto Louzada, Fernando G de Mello, Sérgio T Ferreir. Amyloid-β decreases nitric oxide production in cultured retinal neurons: a possible mechanism for synaptic dysfunction in Alzheimer's disease? Neurochemical research. vol 36. issue 1. 2011-04-18. PMID:20936504. |
amyloid-β decreases nitric oxide production in cultured retinal neurons: a possible mechanism for synaptic dysfunction in alzheimer's disease? |
2011-04-18 |
2023-08-12 |
chicken |
| Leandro T Oliveira, Paulo Roberto Louzada, Fernando G de Mello, Sérgio T Ferreir. Amyloid-β decreases nitric oxide production in cultured retinal neurons: a possible mechanism for synaptic dysfunction in Alzheimer's disease? Neurochemical research. vol 36. issue 1. 2011-04-18. PMID:20936504. |
hyperactivation of nitric oxide synthase (nos) and increased nitric oxide (no) production have been implicated in excitotoxic neuronal damage caused by overactivation of glutamate receptors, and it has been suggested that increased no levels might also play a role in neurotoxicity in alzheimer's disease. |
2011-04-18 |
2023-08-12 |
chicken |