| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Claudine L Bitel, Yicheng Feng, Nizar Souayah, Peter H Frederiks. Increased expression and local accumulation of the prion protein, Alzheimer Aβ peptides, superoxide dismutase 1, and nitric oxide synthases 1 & 2 in muscle in a rabbit model of diabetes. BMC physiology. vol 10. 2011-03-15. PMID:20819221. |
increased expression and local accumulation of the prion protein, alzheimer aβ peptides, superoxide dismutase 1, and nitric oxide synthases 1 & 2 in muscle in a rabbit model of diabetes. |
2011-03-15 |
2023-08-12 |
rabbit |
| Claudine L Bitel, Yicheng Feng, Nizar Souayah, Peter H Frederiks. Increased expression and local accumulation of the prion protein, Alzheimer Aβ peptides, superoxide dismutase 1, and nitric oxide synthases 1 & 2 in muscle in a rabbit model of diabetes. BMC physiology. vol 10. 2011-03-15. PMID:20819221. |
in this study we examined changes in muscle tissue in a classic model of diabetes and hyperglycemia in rabbits to determine if similar dysregulation of alzheimer aβ peptides, the prion protein (prp), and superoxide dismutase 1 (sod1), as well as nitric oxide synthases is produced in muscle in diabetic animals. |
2011-03-15 |
2023-08-12 |
rabbit |
| A P Fernandez, A Pozo-Rodrigalvarez, J Serrano, R Martinez-Murill. Nitric oxide: target for therapeutic strategies in Alzheimer's disease. Current pharmaceutical design. vol 16. issue 25. 2011-02-08. PMID:20698819. |
nitric oxide: target for therapeutic strategies in alzheimer's disease. |
2011-02-08 |
2023-08-12 |
Not clear |
| b' Zdena Kristofikov\\xc3\\xa1, Jan R\\xc3\\xadcn\\xc3\\xbd, Michael Ort, Daniela R\\xc3\\xadpov\\xc3\\xa. Aging and lateralization of the rat brain on a biochemical level. Neurochemical research. vol 35. issue 8. 2010-09-07. PMID:20369289.' |
in the current study, biochemical markers sensitive to alzheimer disease (activities of high-affinity choline uptake and of nitric oxide synthases, expression of 17beta-hydroxysteroid dehydrogenase type 10) were estimated in both hemispheres of young and old male wistar/long evans rats. |
2010-09-07 |
2023-08-12 |
human |
| Jae Yeon Kim, Hyo Jin Lim, Da Yeon Lee, Ji Sun Kim, Do Hee Kim, Hwa Jin Lee, Hee Doo Kim, Raok Jeon, Jae-Ha Ry. In vitro anti-inflammatory activity of lignans isolated from Magnolia fargesii. Bioorganic & medicinal chemistry letters. vol 19. issue 3. 2010-07-06. PMID:19110419. |
the overproduction of nitric oxide (no) and prostaglandin e(2) (pge(2)) causes neurodegenerative diseases, such as alzheimer's disease and parkinson's disease. |
2010-07-06 |
2023-08-12 |
Not clear |
| Noboru Toda, Kazuhide Ayajik. Alzheimer's disease, cerebral blood flow, and nitric oxide. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 135. issue 1. 2010-03-16. PMID:20075566. |
alzheimer's disease, cerebral blood flow, and nitric oxide. |
2010-03-16 |
2023-08-12 |
Not clear |
| Feng Han, Kohji Fukunag. Beta-amyloid accumulation in neurovascular units following brain embolism. Journal of pharmacological sciences. vol 111. issue 2. 2010-01-28. PMID:19783863. |
nitric oxide (no) toxicity is in part mediated by generation of peroxynitrite with concomitant production of superoxide under pathological brain conditions such as ischemia and alzheimer's disease. |
2010-01-28 |
2023-08-12 |
rat |
| Gjumrakch Aliev, Hector H Palacios, Amanda E Lipsitt, Kathryn Fischbach, Bruce T Lamb, Mark E Obrenovich, Ludis Morales, Eldar Gasimov, Valentin Bragi. Nitric oxide as an initiator of brain lesions during the development of Alzheimer disease. Neurotoxicity research. vol 16. issue 3. 2010-01-25. PMID:19526276. |
nitric oxide as an initiator of brain lesions during the development of alzheimer disease. |
2010-01-25 |
2023-08-12 |
human |
| Jie Yu, Jian-ping Ji. [Platelet function in patients with Alzheimer disease: analysis of 40 cases]. Zhonghua yi xue za zhi. vol 89. issue 3. 2009-10-06. PMID:19537035. |
to investigate the platelet aggregation in alzheimer disease (ad) patients and the influence of platelet-derived nitric oxide (no) on such aggregation. |
2009-10-06 |
2023-08-12 |
Not clear |
| Abbas K Ali, William A Banks, Vijaya B Kumar, Gul N Shah, Jessica L Lynch, Susan A Farr, Melissa A Fleegal-DeMotta, John E Morle. Nitric oxide activity and isoenzyme expression in the senescence-accelerated mouse p8 model of Alzheimer's disease: effects of anti-amyloid antibody and antisense treatments. The journals of gerontology. Series A, Biological sciences and medical sciences. vol 64. issue 10. 2009-09-29. PMID:19531769. |
nitric oxide activity and isoenzyme expression in the senescence-accelerated mouse p8 model of alzheimer's disease: effects of anti-amyloid antibody and antisense treatments. |
2009-09-29 |
2023-08-12 |
mouse |
| Benedikt Westerman. Nitric oxide links mitochondrial fission to Alzheimer's disease. Science signaling. vol 2. issue 69. 2009-09-24. PMID:19417214. |
nitric oxide links mitochondrial fission to alzheimer's disease. |
2009-09-24 |
2023-08-12 |
human |
| Huseyin Vural, Burcu Sirin, Nigar Yilmaz, Ibrahim Eren, Namik Deliba. The role of arginine-nitric oxide pathway in patients with Alzheimer disease. Biological trace element research. vol 129. issue 1-3. 2009-07-16. PMID:19099206. |
there are various evidences of the role of nitric oxide in several neuropsychiatric disorders including alzheimer's disease. |
2009-07-16 |
2023-08-12 |
human |
| Dong-Hyung Cho, Tomohiro Nakamura, Jianguo Fang, Piotr Cieplak, Adam Godzik, Zezong Gu, Stuart A Lipto. S-nitrosylation of Drp1 mediates beta-amyloid-related mitochondrial fission and neuronal injury. Science (New York, N.Y.). vol 324. issue 5923. 2009-04-17. PMID:19342591. |
we found that nitric oxide produced in response to beta-amyloid protein, thought to be a key mediator of alzheimer's disease, triggered mitochondrial fission, synaptic loss, and neuronal damage, in part via s-nitrosylation of dynamin-related protein 1 (forming sno-drp1). |
2009-04-17 |
2023-08-12 |
human |
| b' Zdena Kristofikov\\xc3\\xa1, Iryna Kozmikov\\xc3\\xa1, Petra Hovorkov\\xc3\\xa1, Jan R\\xc3\\xadcn\\xc3\\xbd, Petr Zach, Emmerich Majer, Jan Klaschka, Daniela R\\xc3\\xadpov\\xc3\\xa. Lateralization of hippocampal nitric oxide mediator system in people with Alzheimer disease, multi-infarct dementia and schizophrenia. Neurochemistry international. vol 53. issue 5. 2009-02-02. PMID:18647632.' |
lateralization of hippocampal nitric oxide mediator system in people with alzheimer disease, multi-infarct dementia and schizophrenia. |
2009-02-02 |
2023-08-12 |
Not clear |
| Hyo Jin Lim, Hyun-Sun Lee, Jae-Ha Ry. Suppression of inducible nitric oxide synthase and cyclooxygenase-2 expression by tussilagone from Farfarae flos in BV-2 microglial cells. Archives of pharmacal research. vol 31. issue 5. 2008-08-22. PMID:18481023. |
activated microglia produce diverse neurotoxic factors such as nitric oxide (no) and prostaglandin e(2) (pge(2)) that may cause neurodegenerative diseases, including alzheimer's disease and parkinson's disease. |
2008-08-22 |
2023-08-12 |
Not clear |
| C Stefan, Diana Melinte Dumitrica, Carmen Ardelean. [The future started: nitric oxide in glaucoma]. Oftalmologia (Bucharest, Romania : 1990). vol 51. issue 4. 2008-07-28. PMID:18543682. |
nitric oxide has a demonstrate role in many neurodegenerative diseases like: glaucoma, alzheimer disease, multiple sclerosis and cerebral-cardio-vascular diseases. |
2008-07-28 |
2023-08-12 |
Not clear |
| Binbin Wang, Sainan Tan, Ze Yang, Yan-Chen Xie, Jing Wang, Sirui Zhou, Shu Li, Chenguang Zheng, Xu M. Association between Alzheimer's disease and the NOS3 gene Glu298Asp polymorphism in Chinese. Journal of molecular neuroscience : MN. vol 34. issue 2. 2008-05-05. PMID:18183499. |
the oxidative stress caused by nitric oxide (no) in the brain has been proposed as a pathogenic mechanism in alzheimer's disease. |
2008-05-05 |
2023-08-12 |
Not clear |
| Richard A Baxte. Anti-aging properties of resveratrol: review and report of a potent new antioxidant skin care formulation. Journal of cosmetic dermatology. vol 7. issue 1. 2008-05-05. PMID:18254804. |
these include cardiovascular benefits via increased nitric oxide production, down-regulation of vasoactive peptides, lowered levels of oxidized low-density lipoprotein, and cyclooxygenase inhibition; possible benefits on alzheimer's disease by breakdown of beta-amyloid and direct effects on neural tissues; phytohormonal actions; anticancer properties via modulation of signal transduction, which translates into anti-initiation, antipromotion, and antiprogression effects; antimicrobial effects; and sirtuin activation, which is believed to be involved in the caloric restriction-longevity effect. |
2008-05-05 |
2023-08-12 |
human |
| Undurti N Da. Acetylcholinesterase and butyrylcholinesterase as possible markers of low-grade systemic inflammation. Medical science monitor : international medical journal of experimental and clinical research. vol 13. issue 12. 2008-04-11. PMID:18049445. |
plasma levels of c-reactive protein, interleukin-6, tumor necrosis factor-alpha, and lipid peroxides are high whereas those of endothelial nitric oxide are low in insulin resistance, obesity, type 2 diabetes mellitus, hypertension, hyperlipidemias, metabolic syndrome x, and alzheimer's disease suggesting that these diseases are characterized by low-grade systemic inflammation. |
2008-04-11 |
2023-08-12 |
Not clear |
| Metta Pinthong, Stefanie A G Black, Fabiola M Ribeiro, Chumpol Pholpramool, Stephen S G Ferguson, R Jane Rylet. Activity and subcellular trafficking of the sodium-coupled choline transporter CHT is regulated acutely by peroxynitrite. Molecular pharmacology. vol 73. issue 3. 2008-04-07. PMID:17971421. |
excess formation of nitric oxide and superoxide by-products (peroxynitrite, reactive oxygen, and reactive nitrogen species) attenuates cholinergic transmission potentially having a role in alzheimer disease pathogenesis. |
2008-04-07 |
2023-08-12 |
rat |