| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jessica Jiang, Jeremy C S Johnson, Maï-Carmen Requena-Komuro, Elia Benhamou, Harri Sivasathiaseelan, Anthipa Chokesuwattanaskul, Annabel Nelson, Ross Nortley, Rimona S Weil, Anna Volkmer, Charles R Marshall, Doris-Eva Bamiou, Jason D Warren, Chris J D Hard. Comprehension of acoustically degraded speech in Alzheimer's disease and primary progressive aphasia. Brain : a journal of neurology. 2023-05-15. PMID:37184986. |
here we addressed this issue in a cohort of 19 patients with typical alzheimer's disease and 30 patients representing the three canonical syndromes of primary progressive aphasia (nonfluent/agrammatic variant primary progressive aphasia; semantic variant primary progressive aphasia; logopenic variant primary progressive aphasia), compared to 25 healthy age-matched controls. |
2023-05-15 |
2023-08-14 |
human |
| Jessica Jiang, Jeremy C S Johnson, Maï-Carmen Requena-Komuro, Elia Benhamou, Harri Sivasathiaseelan, Anthipa Chokesuwattanaskul, Annabel Nelson, Ross Nortley, Rimona S Weil, Anna Volkmer, Charles R Marshall, Doris-Eva Bamiou, Jason D Warren, Chris J D Hard. Comprehension of acoustically degraded speech in Alzheimer's disease and primary progressive aphasia. Brain : a journal of neurology. 2023-05-15. PMID:37184986. |
mean noise-vocoded speech intelligibility threshold was significantly higher in all patient groups than healthy controls, and significantly higher in alzheimer's disease and logopenic variant primary progressive aphasia than semantic variant primary progressive aphasia (all p < 0.05). |
2023-05-15 |
2023-08-14 |
human |
| Mario F Mendez, Imaad Nasi. Distinguishing Semantic Variant Primary Progressive Aphasia from Alzheimer's Disease. Journal of Alzheimer's disease reports. vol 7. issue 1. 2023-04-24. PMID:37090957. |
distinguishing semantic variant primary progressive aphasia from alzheimer's disease. |
2023-04-24 |
2023-08-14 |
Not clear |
| Mario F Mendez, Imaad Nasi. Distinguishing Semantic Variant Primary Progressive Aphasia from Alzheimer's Disease. Journal of Alzheimer's disease reports. vol 7. issue 1. 2023-04-24. PMID:37090957. |
the differentiation of semantic variant primary progressive aphasia from dementia and alzheimer's disease can be difficult, particularly when the semantic anomia is pronounced. |
2023-04-24 |
2023-08-14 |
Not clear |
| Mario F Mendez, Imaad Nasi. Distinguishing Semantic Variant Primary Progressive Aphasia from Alzheimer's Disease. Journal of Alzheimer's disease reports. vol 7. issue 1. 2023-04-24. PMID:37090957. |
the evaluation was consistent for semantic variant primary progressive aphasia with degradation of semantic knowledge and focal anterior temporal atrophy and hypometabolism. |
2023-04-24 |
2023-08-14 |
Not clear |
| Federica Agosta, Edoardo Gioele Spinelli, Silvia Basaia, Camilla Cividini, Francesco Falbo, Costanza Pavone, Nilo Riva, Elisa Canu, Veronica Castelnovo, Giuseppe Magnani, Francesca Caso, Paola Caroppo, Sara Prioni, Cristina Villa, Lucio Tremolizzo, Ildebrando Appollonio, Vincenzo Silani, Keith Anthony Josephs, Jennifer Whitwell, Massimo Filipp. Functional Connectivity From Disease Epicenters in Frontotemporal Dementia. Neurology. 2023-04-17. PMID:37068954. |
here, we used a novel graph-theory-based mri paradigm to explore functional connectivity reorganization, discerning between direct and indirect connections from disease epicenters, and its relationship with neurodegeneration across clinical presentations of the frontotemporal dementia (ftd) spectrum, including behavioral variant of ftd (bvftd), non-fluent (nfvppa) and semantic variants of primary progressive aphasia (svppa). |
2023-04-17 |
2023-08-14 |
Not clear |
| C R A Silveira, E Mitchell, M Restrepo-Martinez, K Coleman, R Ruiz-Garcia, E Finge. Changes in motor activity level in individuals with frontotemporal dementia. Journal of neurology. 2023-04-16. PMID:37062017. |
eighty-two charts were retrospectively reviewed from patients meeting consensus criteria for one of the three main clinical subtypes of ftd: probable bvftd, semantic variant primary progressive aphasia (ppa), or non-fluent variant ppa. |
2023-04-16 |
2023-08-14 |
human |
| Maxime Montembeault, Zachary A Miller, Amandine Geraudie, Peter Pressman, Antoine Slegers, Carly Millanski, Abigail Licata, Buddhika Ratnasiri, Maria Luisa Mandelli, Maya Henry, Yann Cobigo, Howard J Rosen, Bruce L Miller, Simona M Brambati, Maria Luisa Gorno-Tempini, Giovanni Battistell. Spared speech fluency is associated with increased functional connectivity in the speech production network in semantic variant primary progressive aphasia. Brain communications. vol 5. issue 2. 2023-04-11. PMID:37038501. |
spared speech fluency is associated with increased functional connectivity in the speech production network in semantic variant primary progressive aphasia. |
2023-04-11 |
2023-08-14 |
Not clear |
| Maxime Montembeault, Zachary A Miller, Amandine Geraudie, Peter Pressman, Antoine Slegers, Carly Millanski, Abigail Licata, Buddhika Ratnasiri, Maria Luisa Mandelli, Maya Henry, Yann Cobigo, Howard J Rosen, Bruce L Miller, Simona M Brambati, Maria Luisa Gorno-Tempini, Giovanni Battistell. Spared speech fluency is associated with increased functional connectivity in the speech production network in semantic variant primary progressive aphasia. Brain communications. vol 5. issue 2. 2023-04-11. PMID:37038501. |
semantic variant primary progressive aphasia is a clinical syndrome characterized by marked semantic deficits, anterior temporal lobe atrophy and reduced connectivity within a distributed set of regions belonging to the functional network associated with semantic processing. |
2023-04-11 |
2023-08-14 |
Not clear |
| Maxime Montembeault, Zachary A Miller, Amandine Geraudie, Peter Pressman, Antoine Slegers, Carly Millanski, Abigail Licata, Buddhika Ratnasiri, Maria Luisa Mandelli, Maya Henry, Yann Cobigo, Howard J Rosen, Bruce L Miller, Simona M Brambati, Maria Luisa Gorno-Tempini, Giovanni Battistell. Spared speech fluency is associated with increased functional connectivity in the speech production network in semantic variant primary progressive aphasia. Brain communications. vol 5. issue 2. 2023-04-11. PMID:37038501. |
however, to fully depict the clinical signature of semantic variant primary progressive aphasia, it is necessary to also characterize preserved neural networks and linguistic abilities, such as those subserving speech production. |
2023-04-11 |
2023-08-14 |
Not clear |
| Maxime Montembeault, Zachary A Miller, Amandine Geraudie, Peter Pressman, Antoine Slegers, Carly Millanski, Abigail Licata, Buddhika Ratnasiri, Maria Luisa Mandelli, Maya Henry, Yann Cobigo, Howard J Rosen, Bruce L Miller, Simona M Brambati, Maria Luisa Gorno-Tempini, Giovanni Battistell. Spared speech fluency is associated with increased functional connectivity in the speech production network in semantic variant primary progressive aphasia. Brain communications. vol 5. issue 2. 2023-04-11. PMID:37038501. |
in this case-control observational study, we employed whole-brain seed-based connectivity on task-free mri data of 32 semantic variant primary progressive aphasia patients and 46 healthy controls to investigate the functional connectivity of the speech production network and its relationship with the underlying grey matter. |
2023-04-11 |
2023-08-14 |
Not clear |
| Maxime Montembeault, Zachary A Miller, Amandine Geraudie, Peter Pressman, Antoine Slegers, Carly Millanski, Abigail Licata, Buddhika Ratnasiri, Maria Luisa Mandelli, Maya Henry, Yann Cobigo, Howard J Rosen, Bruce L Miller, Simona M Brambati, Maria Luisa Gorno-Tempini, Giovanni Battistell. Spared speech fluency is associated with increased functional connectivity in the speech production network in semantic variant primary progressive aphasia. Brain communications. vol 5. issue 2. 2023-04-11. PMID:37038501. |
in semantic variant primary progressive aphasia patients, preserved (verbal agility) and increased (articulation rate) speech fluency measures correlated with increased connectivity between inferior frontal and supramarginal regions. |
2023-04-11 |
2023-08-14 |
Not clear |
| Maxime Montembeault, Zachary A Miller, Amandine Geraudie, Peter Pressman, Antoine Slegers, Carly Millanski, Abigail Licata, Buddhika Ratnasiri, Maria Luisa Mandelli, Maya Henry, Yann Cobigo, Howard J Rosen, Bruce L Miller, Simona M Brambati, Maria Luisa Gorno-Tempini, Giovanni Battistell. Spared speech fluency is associated with increased functional connectivity in the speech production network in semantic variant primary progressive aphasia. Brain communications. vol 5. issue 2. 2023-04-11. PMID:37038501. |
collectively, these results provide a compelling model for studying compensation mechanisms in response to disease that might inform the design of future rehabilitation strategies in semantic variant primary progressive aphasia. |
2023-04-11 |
2023-08-14 |
Not clear |
| Sandrine Basaglia-Pappas, Bernard Laurent, Jean-Claude Getenet, Anne Boulangé, Aurelia Rendón de laCruz, Isabelle Simoes Loureiro, Laurent Lefebvr. Executive Profile of the Logopenic Variant of Primary Progressive Aphasia: Comparison with the Semantic and Non-Fluent Variants and Alzheimer's Disease. Brain sciences. vol 13. issue 3. 2023-03-29. PMID:36979216. |
executive profile of the logopenic variant of primary progressive aphasia: comparison with the semantic and non-fluent variants and alzheimer's disease. |
2023-03-29 |
2023-08-14 |
Not clear |
| Sandrine Basaglia-Pappas, Bernard Laurent, Jean-Claude Getenet, Anne Boulangé, Aurelia Rendón de laCruz, Isabelle Simoes Loureiro, Laurent Lefebvr. Executive Profile of the Logopenic Variant of Primary Progressive Aphasia: Comparison with the Semantic and Non-Fluent Variants and Alzheimer's Disease. Brain sciences. vol 13. issue 3. 2023-03-29. PMID:36979216. |
the logopenic variant of primary progressive aphasia (lvppa) shows different features from the non-fluent (nfvppa) and semantic (svppa) variants of ppa. |
2023-03-29 |
2023-08-14 |
Not clear |
| Wencai Ding, Peng Ren, Liye Yi, Yao Si, Fan Yang, Zhipeng Li, Hongbo Bao, Shi Yan, Xinyu Zhang, Siyang Li, Xia Liang, Lifen Ya. Association of cortical and subcortical microstructure with disease severity: impact on cognitive decline and language impairments in frontotemporal lobar degeneration. Alzheimer's research & therapy. vol 15. issue 1. 2023-03-21. PMID:36941645. |
in this study, we investigated cortical and subcortical microstructure underlying cognitive and language impairments across behavioral variant of frontotemporal dementia (bvftd), semantic variant of primary progressive aphasia (svppa), and nonfluent variant of primary progressive aphasia (nfvppa) subtypes. |
2023-03-21 |
2023-08-14 |
Not clear |
| Anthipa Chokesuwattanaskul, Harmony Jiang, Rebecca L Bond, Daniel A Jimenez, Lucy L Russell, Harri Sivasathiaseelan, Jeremy C S Johnson, Elia Benhamou, Jennifer L Agustus, Janneke E P van Leeuwen, Peerapat Chokesuwattanaskul, Chris J D Hardy, Charles R Marshall, Jonathan D Rohrer, Jason D Warre. The architecture of abnormal reward behaviour in dementia: multimodal hedonic phenotypes and brain substrate. Brain communications. vol 5. issue 2. 2023-03-21. PMID:36942157. |
we studied 27 patients with behavioural variant frontotemporal dementia, 58 with primary progressive aphasia (22 semantic variant, 24 non-fluent/agrammatic variant and 12 logopenic) and 34 with typical amnestic alzheimer's disease, in relation to 42 healthy older individuals. |
2023-03-21 |
2023-08-14 |
Not clear |
| Kiran Samra, Amy M MacDougall, Arabella Bouzigues, Martina Bocchetta, David M Cash, Caroline V Greaves, Rhian S Convery, Chris Hardy, John C van Swieten, Harro Seelaar, Lize C Jiskoot, Fermin Moreno, Raquel Sanchez-Valle, Robert Laforce, Caroline Graff, Mario Masellis, Maria Carmela Tartaglia, James B Rowe, Barbara Borroni, Elizabeth Finger, Matthis Synofzik, Daniela Galimberti, Rik Vandenberghe, Alexandre de Mendonça, Chris R Butler, Alexander Gerhard, Simon Ducharme, Isabelle Le Ber, Isabel Santana, Florence Pasquier, Johannes Levin, Markus Otto, Sandro Sorbi, Jason D Warren, Jonathan D Rohrer, Lucy L Russel. Genetic forms of primary progressive aphasia within the GENetic Frontotemporal dementia Initiative (GENFI) cohort: comparison with sporadic primary progressive aphasia. Brain communications. vol 5. issue 2. 2023-03-20. PMID:36938528. |
this study aimed to understand the clinical, cognitive and imaging phenotype of the genetic forms of primary progressive aphasia in comparison to the canonical nonfluent, semantic and logopenic subtypes seen in sporadic disease. |
2023-03-20 |
2023-08-14 |
human |
| Shalom K Henderson, Katie A Peterson, Karalyn Patterson, Matthew A Lambon Ralph, James B Row. Verbal fluency tests assess global cognitive status but have limited diagnostic differentiation: evidence from a large-scale examination of six neurodegenerative diseases. Brain communications. vol 5. issue 2. 2023-03-13. PMID:36910418. |
we assessed whether various measures of fluency performance could differentiate between alzheimer's disease, behavioural variant of frontotemporal dementia, non-fluent and semantic variants of primary progressive aphasia, progressive supranuclear palsy, corticobasal syndrome and healthy controls. |
2023-03-13 |
2023-08-14 |
Not clear |
| Shalom K Henderson, Katie A Peterson, Karalyn Patterson, Matthew A Lambon Ralph, James B Row. Verbal fluency tests assess global cognitive status but have limited diagnostic differentiation: evidence from a large-scale examination of six neurodegenerative diseases. Brain communications. vol 5. issue 2. 2023-03-13. PMID:36910418. |
word frequency was the strongest discriminator for semantic variant of primary progressive aphasia versus other groups. |
2023-03-13 |
2023-08-14 |
Not clear |