| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Angela Patricia França, Marissa Giovanna Schamne, Bruna Soares de Souza, Débora da Luz Scheffer, Angelica Karina Bernardelli, Thiago Corrêa, Geison de Souza Izídio, Alexandra Latini, José Eduardo da Silva-Santos, Paula M Canas, Rodrigo A Cunha, Rui Daniel Predige. Caffeine Consumption plus Physical Exercise Improves Behavioral Impairments and Stimulates Neuroplasticity in Spontaneously Hypertensive Rats (SHR): an Animal Model of Attention Deficit Hyperactivity Disorder. Molecular neurobiology. vol 57. issue 9. 2021-06-03. PMID:32621279. |
here, we evaluated the effects of caffeine consumption (0.3 mg/ml in drinking water) plus physical exercise in running wheels during 6 weeks-starting during either adolescence (30 days old) or adulthood (4-5 months old)-on behavioral performance (including olfactory discrimination, open field, object recognition, and water maze tests) on the brain levels of monoamines (by high-performance liquid chromatography), on proteins related to synaptic plasticity and on brain-derived neurotrophic factor signaling (by western blot analysis) in spontaneously hypertensive rats (shrs), a validated animal model of adhd. |
2021-06-03 |
2023-08-13 |
rat |
| Alma Y Galvez-Contreras, Tania Campos-Ordonez, Rocio E Gonzalez-Castaneda, Oscar Gonzalez-Pere. Alterations of Growth Factors in Autism and Attention-Deficit/Hyperactivity Disorder. Frontiers in psychiatry. vol 8. 2020-09-30. PMID:28751869. |
in this concise review, we summarize the current evidence that supports the role of brain-derived neurotrophic factor, insulin-like growth factor 2, hepatocyte growth factor (hgf), glial-derived neurotrophic factor, nerve growth factor, neurotrophins 3 and 4, and epidermal growth factor in the pathogenesis of adhd and asd. |
2020-09-30 |
2023-08-13 |
Not clear |
| Na Wang, Zhichao Wang, Fengwu Yan, Wei F. [Correlation between single nucleotide polymorphisms of neurotrophic factors and executive function characteristics in children with attention deficit hyperactivity disorder]. Wei sheng yan jiu = Journal of hygiene research. vol 48. issue 4. 2019-11-14. PMID:31601338. |
to investigate the correlation between the polymorphisms of(brain derived neurotrophic factor, bdnf)bdnf gene rs11030104 and rs2030324 and executive function in children with attention deficit hyperactivity disorder(adhd). |
2019-11-14 |
2023-08-13 |
Not clear |
| Se-Hoon Shim, Young Hwangbo, Hee-Jung Yoon, Young-Joon Kwon, Hwa-Young Lee, Jung-A Hwang, Yong-Ku Ki. Increased levels of plasma glial-derived neurotrophic factor in children with attention deficit hyperactivity disorder. Nordic journal of psychiatry. vol 69. issue 7. 2016-06-22. PMID:25753832. |
recent evidence suggests that neurotrophic growth factor systems, including brain-derived neurotrophic factor, might be involved in the pathophysiology of attention deficit hyperactivity disorder (adhd). |
2016-06-22 |
2023-08-13 |
Not clear |
| Haimei Li, Lu Liu, Yilang Tang, Ning Ji, Li Yang, Qiujin Qian, Yufeng Wan. Sex-specific association of brain-derived neurotrophic factor (BDNF) Val66Met polymorphism and plasma BDNF with attention-deficit/hyperactivity disorder in a drug-naïve Han Chinese sample. Psychiatry research. vol 217. issue 3. 2015-04-02. PMID:24713358. |
a functional polymorphism of the brain derived neurotrophic factor gene (bdnf) (val66met) has been suggested to be involved in the pathogenesis of attention-deficit/hyperactivity disorder (adhd). |
2015-04-02 |
2023-08-13 |
Not clear |
| Bung-Nyun Kim, Tarrant D R Cummins, Jae-Won Kim, Mark A Bellgrove, Soon-Beom Hong, Sook-Hyung Song, Min-Sup Shin, Soo-Churl Cho, Ji-Hoon Kim, Jung-Woo Son, Yun-Mi Shin, Un-Sun Chung, Doug-Hyun Ha. Val/Val genotype of brain-derived neurotrophic factor (BDNF) Val⁶⁶Met polymorphism is associated with a better response to OROS-MPH in Korean ADHD children. The international journal of neuropsychopharmacology. vol 14. issue 10. 2012-07-30. PMID:21733227. |
research on psychostimulants, analysis of animal models and genetic association studies all suggest that the brain-derived neurotrophic factor gene (bdnf) may be a good candidate for pharmacogenetic studies of attention deficit hyperactivity disorder (adhd). |
2012-07-30 |
2023-08-12 |
Not clear |
| Trevor Archer, Richard M Kostrzew. Physical exercise alleviates ADHD symptoms: regional deficits and development trajectory. Neurotoxicity research. vol 21. issue 2. 2012-04-17. PMID:21850535. |
brain-derived neurotrophic factor, an essential element in normal brain development that promotes health-associated behaviors and quality-of-life, though reduced in adhd, is increased markedly by the intervention of regular physical exercise. |
2012-04-17 |
2023-08-12 |
Not clear |
| C Sánchez-Mora, M Ribasés, J A Ramos-Quiroga, M Casas, R Bosch, A Boreatti-Hümmer, M Heine, C P Jacob, K-P Lesch, O B Fasmer, P M Knappskog, J J Sandra Kooij, C Kan, J K Buitelaar, E Mick, P Asherson, S V Faraone, B Franke, S Johansson, J Haavik, A Reif, M Bayés, B Corman. Meta-analysis of brain-derived neurotrophic factor p.Val66Met in adult ADHD in four European populations. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 153B. issue 2. 2010-12-20. PMID:19603419. |
meta-analysis of brain-derived neurotrophic factor p.val66met in adult adhd in four european populations. |
2010-12-20 |
2023-08-12 |
Not clear |
| B G Schimmelmann, S Friedel, A Dempfle, A Warnke, K P Lesch, S Walitza, T J Renner, M Romanos, B Herpertz-Dahlmann, M Linder, H Schäfer, C Seitz, H Palmason, C Freitag, J Meyer, K Konrad, A Hinney, J Hebebran. No evidence for preferential transmission of common valine allele of the Val66Met polymorphism of the brain-derived neurotrophic factor gene (BDNF) in ADHD. Journal of neural transmission (Vienna, Austria : 1996). vol 114. issue 4. 2007-10-04. PMID:17219016. |
a coding snp (rs6265, val66met) of the brain-derived neurotrophic factor gene (bdnf) has recently been associated with adhd. |
2007-10-04 |
2023-08-12 |
Not clear |
| B G Schimmelmann, S Friedel, A Dempfle, A Warnke, K P Lesch, S Walitza, T J Renner, M Romanos, B Herpertz-Dahlmann, M Linder, H Schäfer, C Seitz, H Palmason, C Freitag, J Meyer, K Konrad, A Hinney, J Hebebran. No evidence for preferential transmission of common valine allele of the Val66Met polymorphism of the brain-derived neurotrophic factor gene (BDNF) in ADHD. Journal of neural transmission (Vienna, Austria : 1996). vol 114. issue 4. 2007-10-04. PMID:17219016. |
no evidence for preferential transmission of common valine allele of the val66met polymorphism of the brain-derived neurotrophic factor gene (bdnf) in adhd. |
2007-10-04 |
2023-08-12 |
Not clear |
| Agnieszka Słopień, Monika Dmitrzak-Weglarz, Filip Rybakowski, Andrzej Rajewski, Joanna Hause. [Genetic background of ADHD: genes of the serotonergic system, other candidate genes, endophenotype]. Psychiatria polska. vol 40. issue 1. 2007-03-20. PMID:16756026. |
other possible factors in adhd background are substance influence on brain maturation, including n-methyl-d aspartate glutamate receptor 2a gene polymorphism (grin2a) and brain derived neurotrophic factor (bdnf) gene. |
2007-03-20 |
2023-08-12 |
Not clear |
| Barbara Geller, Rebecca Tillma. Prepubertal and early adolescent bipolar I disorder: review of diagnostic validation by Robins and Guze criteria. The Journal of clinical psychiatry. vol 66 Suppl 7. 2005-10-25. PMID:16124838. |
validation of the phenotype was shown according to robins and guze criteria: unique symptoms that did not overlap with those of adhd, stability of the diagnosis (did not become adhd or other disorders on follow-up) as shown by a 4-year prospective longitudinal study, significantly higher familial aggregation of bipolar disorder in relatives of pea-bp versus adhd and healthy control probands, and family-based linkage disequilibrium of the brain-derived neurotrophic factor val66 allele in pea-bp probands. |
2005-10-25 |
2023-08-12 |
human |