| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shania Mereen Soman, Nandita Vijayakumar, Phoebe Thomson, Gareth Ball, Christian Hyde, Timothy J Sil. Cortical structural and functional coupling during development and implications for attention deficit hyperactivity disorder. Translational psychiatry. vol 13. issue 1. 2023-07-11. PMID:37433763. |
overall, weaker coupling was observed in children with adhd, mainly in the prefrontal cortex, superior temporal gyrus, and inferior parietal cortex. |
2023-07-11 |
2023-08-14 |
Not clear |
| Daichi Watanabe, Takamitsu Watanab. Distinct frontoparietal brain dynamics underlying the co-occurrence of autism and ADHD. eNeuro. 2023-07-06. PMID:37414550. |
in contrast, their adhd-like traits were grounded on a unique neural mechanism that was unseen in pure adhd: the core symptoms of pure adhd were associated with the overly flexible whole-brain dynamics that were triggered by the unstable activity of the dorsal-attention network and the left parietal cortex; by contrast, the adhd-like cognitive instability of the asd+adhd condition was correlated with the atypically frequent neural transition along a specific brain state pathway, which was induced by the atypically unstable activity of the frontoparietal control network and the left prefrontal cortex. |
2023-07-06 |
2023-08-14 |
Not clear |
| Vahid Nejati, Fateme Mirikaram, Jamal Amani Ra. Transcranial direct current stimulation alters the process of reward processing in children with ADHD: Evidence from cognitive modeling. Neurophysiologie clinique = Clinical neurophysiology. vol 53. issue 3. 2023-05-24. PMID:37224617. |
the ventromedial prefrontal cortex (vmpfc) and dorsolateral prefrontal cortex (dlpfc) are the neural underpinnings of reward processing, which is impaired in individuals with attention deficit hyperactivity disorder (adhd). |
2023-05-24 |
2023-08-14 |
Not clear |
| Lauren M Friedman, Samuel J Eckrich, Mark D Rapport, Corey J Bohil, Catrina Calu. Working and short-term memory in children with ADHD: an examination of prefrontal cortical functioning using functional Near-Infrared Spectroscopy (fNIRS). Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence. 2023-05-18. PMID:37199502. |
working memory impairments are an oft-reported deficit among children with adhd, and complementary neuroimaging studies implicate reductions in prefrontal cortex (pfc) structure and function as a neurobiological explanation. |
2023-05-18 |
2023-08-14 |
Not clear |
| Yike Zhu, Siqi Liu, Fan Zhang, Yongying Ren, Tingyu Zhang, Jing Sun, Xin Wang, Lin Wang, Jian Yan. Response inhibition in children with different subtypes/presentations of attention deficit hyperactivity disorder: A near-infrared spectroscopy study. Frontiers in neuroscience. vol 17. 2023-03-20. PMID:36937678. |
executive dysfunction in children with attention deficit hyperactivity disorder (adhd) is thought to be closely related to the prefrontal cortex (pfc). |
2023-03-20 |
2023-08-14 |
Not clear |
| Yike Zhu, Siqi Liu, Fan Zhang, Yongying Ren, Tingyu Zhang, Jing Sun, Xin Wang, Lin Wang, Jian Yan. Response inhibition in children with different subtypes/presentations of attention deficit hyperactivity disorder: A near-infrared spectroscopy study. Frontiers in neuroscience. vol 17. 2023-03-20. PMID:36937678. |
however, there is controversy over the activation of the pfc in children with adhd. |
2023-03-20 |
2023-08-14 |
Not clear |
| Yike Zhu, Siqi Liu, Fan Zhang, Yongying Ren, Tingyu Zhang, Jing Sun, Xin Wang, Lin Wang, Jian Yan. Response inhibition in children with different subtypes/presentations of attention deficit hyperactivity disorder: A near-infrared spectroscopy study. Frontiers in neuroscience. vol 17. 2023-03-20. PMID:36937678. |
thus, this study aimed to explore the activation of the pfc in children with different subtypes of adhd during executive function task. |
2023-03-20 |
2023-08-14 |
Not clear |
| Scott A Jones, Jessica Tipsord, Bonnie J Nagel, Joel T Nig. A preliminary study of white matter correlates of a laboratory measure of attention and motor stability in attention-deficit/hyperactivity disorder. Journal of psychiatric research. vol 160. 2023-02-21. PMID:36804107. |
further, fa in white matter regions of the prefrontal cortex appeared to mediate the relationship between adhd status and motor activity on the qbtest. |
2023-02-21 |
2023-08-14 |
Not clear |
| Lana Bach-Morrow, Francesco Boccalatte, Antonio DeRosa, David Devos, Carmen Garcia-Sanchez, Matilde Inglese, Amgad Drob. Functional changes in prefrontal cortex following frequency-specific training. Scientific reports. vol 12. issue 1. 2022-11-26. PMID:36434008. |
numerous studies indicate a significant role of pre-frontal circuits (pfc) connectivity involving attentional and reward neural networks within attention deficit hyperactivity disorder (adhd) pathophysiology. |
2022-11-26 |
2023-08-14 |
human |
| Mahasweta Chatterjee, Sharmistha Saha, Nilanjana Dutta, Swagata Sinha, Kanchan Mukhopadhya. Kainate receptor subunit 1 (GRIK1) risk variants and GRIK1 deficiency were detected in the Indian ADHD probands. Scientific reports. vol 12. issue 1. 2022-11-03. PMID:36323684. |
executive dysfunctions caused by structural and functional abnormalities of the prefrontal cortex were reported in patients with attention deficit hyperactivity disorder (adhd). |
2022-11-03 |
2023-08-14 |
Not clear |
| Hsin-Yung Chen, Chia-Yen Yang, Tsung-Hsun Hsieh, Chih-Wei Peng, Li-Ling Chuang, Ying-Ling Chang, Huang-Ju Chi, Hsin-Min Lee, Hsin-Yi Lian. Effects of Transcranial Direct Current Stimulation on Improving Performance of Delayed- Reinforcement Attentional Set-Shifting Tasks in Attention-Deficit/Hyperactivity Disorder Rat Model. Behavioural brain research. 2022-10-07. PMID:36206819. |
behavioral flexibility (or set-shifting), which is regulated by the prefrontal cortex (pfc), is often impaired in patients with attention-deficit/hyperactivity disorder (adhd), which is characterized by poor inhibitory control and reinforcement learning. |
2022-10-07 |
2023-08-14 |
rat |
| Huzeyfe Barham, Deniz Büyükgök, Serkan Aksu, Ahmet Zihni Soyata, Gamze Bulut, Gaye Eskicioğlu, Işın Baral Kulaksızoğl. Evidence for modulation of planning and working memory capacities by transcranial direct current stimulation in a sample of adults with attention deficit hyperactivity disorder. Neuroscience letters. 2022-09-24. PMID:36152744. |
executive dysfunction has been considered to have a principal role in adhd and has previously been linked to activity alterations in the prefrontal cortex. |
2022-09-24 |
2023-08-14 |
Not clear |
| Huzeyfe Barham, Deniz Büyükgök, Serkan Aksu, Ahmet Zihni Soyata, Gamze Bulut, Gaye Eskicioğlu, Işın Baral Kulaksızoğl. Evidence for modulation of planning and working memory capacities by transcranial direct current stimulation in a sample of adults with attention deficit hyperactivity disorder. Neuroscience letters. 2022-09-24. PMID:36152744. |
transcranial direct current stimulation (tdcs) is a noninvasive brain stimulation technique that may modulate prefrontal cortex activity and induce neuroplasticity, with preliminary results in adhd. |
2022-09-24 |
2023-08-14 |
Not clear |
| Gerry Leisman, Robert Melill. Front and center: Maturational dysregulation of frontal lobe functional neuroanatomic connections in attention deficit hyperactivity disorder. Frontiers in neuroanatomy. vol 16. 2022-09-09. PMID:36081853. |
adhd children demonstrate decreased activation of the right and middle prefrontal cortex. |
2022-09-09 |
2023-08-14 |
Not clear |
| Katharine E Musella, Lisa L Weyand. Attention-deficit hyperactivity disorder and youth's emotion dysregulation: A systematic review of fMRI studies. Applied neuropsychology. Child. 2022-09-06. PMID:36065486. |
although studies varied in the structures investigated, the most notable differences appeared in the prefrontal cortex, orbitofrontal cortex, amygdala, and ventral striatum in adhd participants. |
2022-09-06 |
2023-08-14 |
human |
| Yaojin Li, Jianwen Chen, Xintong Zheng, Jianxiu Liu, Cong Peng, Youguo Liao, Yan Li. Cognitive deficit in adults with ADHD lies in the cognitive state disorder rather than the working memory deficit: A functional near-infrared spectroscopy study. Journal of psychiatric research. vol 154. 2022-08-27. PMID:36029728. |
the functional near-infrared spectroscopy (fnirs) was combined with three perspectives from behavioral and spatial and temporal activation characteristics of blood oxygen levels in the prefrontal cortex to examine the psychological and neuroprocessing characteristics of adult adhd. |
2022-08-27 |
2023-08-14 |
Not clear |
| Mohammad Ali Salehinejad, Younes Vosough, Vahid Nejat. The Impact of Bilateral Anodal tDCS over Left and Right DLPFC on Executive Functions in Children with ADHD. Brain sciences. vol 12. issue 8. 2022-08-26. PMID:36009161. |
the dorsolateral prefrontal cortex (dlpfc) is the most targeted region of tdcs studies in adhd. |
2022-08-26 |
2023-08-14 |
Not clear |
| Jing Wang, Xin-Qiang Ni, Li-Min Li, Ying-Zhao Liao, Yao Chen, Chun-Ling Huan. [Effect of Rehmanniae Radix Praeparata on energy metabolism in prefrontal cortex of rats with attention deficit hyperactivity disorder based on "static Yin and dynamic Yang" theory]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 47. issue 13. 2022-07-19. PMID:35850809. |
the present study investigated the effect of rehmanniae radix praeparata(rrp) on the energy metabolism of prefrontal cortex(pfc) of spontaneously hypertensive rats with attention deficit hyperactivity disorder(adhd) based on the "static yin and dynamic yang" theory.thirty spontaneously hypertensive male rats aged 3 weeks were randomly divided into a model group, a methylphenidate(mph) group(2 mg·kg~(-1)), and an rrp group(2.4 g·kg~(-1)).wistar-kyoto(wky) male rats of the same age were assigned to the normal group.rats were treated with corresponding drugs twice per day, and those in the model group and the normal group received the same volume of 0.9% sodium carboxymethyl cellulose(cmc-na) solution by gavage.the open-field test was performed to evaluate the spontaneous and impulsive behaviors of rats before treatment and on the 4~(th) week after treatment.four weeks after treatment, pfc was isolated and mitochondria were prepared.the content of adenosine triphosphate(atp), adenosine diphosphate(adp), and adenosine monophosphate(amp) in the pfc was determined by high-performance liquid chromatography(hplc), and energy charge(ec) was calculated.the parameters related to mitochondrial respiratory function were measured by the clark oxygen electrode, specifically, state 3 respiration(st3), state 4 respiration(st4), and respiratory control rate(rcr).enzymatic activities of succinate dehydrogenase(sdh), cytochrome c oxidase(cox), na~+-k~+-atpase, and ca~(2+)-mg~(2+)-atpase were measured by chemical colorimetry.mitochondrial permeability transition pore(mptp) opening was measured by spectrophotometry.protein expression of glucose transporter 1(glut1) and glut3 in pfc was tested by western blot.compared with the results in the model group, rrp could significantly reduce the total distance of movement, vertical times, and distance in the central area in the open field test(p<0.05 or p<0.01), increase the content of atp and ec, decrease the content of amp(p<0.05), elevate st3 and rcr(p<0.05), potentiate activities of sdh, cox, na~+-k~+-atpase, and ca~(2+)-mg~(2+)-atpase(p<0.05 or p<0.01), inhibit the opening of mptp, and increase the expression levels of glut1 and glut3 proteins(p<0.05).it was inferred that rrp could inhibit hyperacti-vity and impulsivity by improving the energy metabolism disorder in pfc of adhd rats, and its mechanism may be related to the improvement of mitochondrial respiratory function, potentiation of na~+-k~+-atpase, ca~(2+)-mg~(2+)-atpase, and mitochondrial respiratory enzymes, inhibition of the opening of mptp, and up-regulation of the expression of glucose transporter proteins.this study initially reveals the biological connotation of the "static yin and dynamic yang" theory in adhd. |
2022-07-19 |
2023-08-14 |
rat |
| Nikhil M Urs, Sharonda Harris, Sara M Green, Mayank M Kuma. A Role for Cortical Dopamine in the Paradoxical Calming Effects of Psychostimulants. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35554609. |
together, these data suggest that elevation of pfc dopamine and not norepinephrine or serotonin as a convergent mechanism for the paradoxical psychostimulant effects observed in adhd therapy. |
2022-05-13 |
2023-08-13 |
mouse |
| D J Heal, J Gosden, S L Smit. New Drugs to Treat ADHD: Opportunities and Challenges in Research and Development. Current topics in behavioral neurosciences. 2022-05-04. PMID:35507283. |
what emerges confirms and consolidates the hypothesis that clinically effective adhd drugs indirectly or directly increase catecholaminergic neurotransmission in the prefrontal cortex (pfc). |
2022-05-04 |
2023-08-13 |
Not clear |