| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jeong Hyun Jeong, Haeun Lee, Doyoung Kim, Eunseo Park, Jiwan Woo, Yakdol Cho, Gyochang Keum, Ansoo Lee, Taek Kang, Jeongjin Kim, Hyunah Choo, Sanghee Lee, Byungsun Jeo. Identification of an Antagonist Targeting G Protein and β-Arrestin Signaling Pathways of 5-HT ACS chemical neuroscience. 2024-02-22. PMID:38387042. |
identification of an antagonist targeting g protein and β-arrestin signaling pathways of 5-ht in consideration of the limited number of fda-approved drugs for autism spectrum disorder (asd), significant efforts have been devoted to identifying novel drug candidates. |
2024-02-22 |
2024-02-25 |
Not clear |
| Kavitha Ukkirapandian, Kayalvizhi Elumalai, Karthika Priyadharshini Udaykumar, Sundaravadivel Vp, Muthulakshmi Rangasm. Behavioral and Biochemical Assays for Autism Models of Wistar Rats. Cureus. vol 16. issue 1. 2024-02-13. PMID:38344592. |
oxidative stress, increased proinflammatory markers, and increased serotonin were recorded in the autism group. |
2024-02-13 |
2024-02-15 |
rat |
| Paula A Gajeswski-Kurdziel, Allison E Walsh, Randy D Blakel. Functional and pathological consequences of being fast on the uptake: Protein kinase G and p38α MAPK regulation of serotonin transporters. Current research in physiology. vol 7. 2024-02-01. PMID:38298474. |
serotonin (5-hydroxytryptamine, 5-ht) signaling plays an important role in dynamic control of peripheral and central nervous system physiology, with altered 5-ht homeostasis implicated in a significant number of disorders, ranging from pulmonary, bowel, and metabolic disease to depression, obsessive-compulsive disorder, and autism spectrum disorder (asd). |
2024-02-01 |
2024-02-03 |
Not clear |
| Dheeraj Rai, Doug Webb, Amanda Lewis, Leonora Cotton, Jade Eloise Norris, Regi Alexander, David S Baldwin, Traolach Brugha, Madeleine Cochrane, Maria Chiara Del Piccolo, Emma J Glasson, Katherine K Hatch, David Kessler, Peter E Langdon, Helen Leonard, Stephanie J MacNeill, Nicola Mills, Maximiliano Vazquez Morales, Zoe Morgan, Raja Mukherjee, Alba X Realpe, Ailsa Russell, Sergio Starkstein, Jodi Taylor, Nicholas Turner, Joanna Thorn, Jack Welch, Nicola Wile. Sertraline for anxiety in adults with a diagnosis of autism (STRATA): study protocol for a pragmatic, multicentre, double-blind, placebo-controlled randomised controlled trial. Trials. vol 25. issue 1. 2024-01-11. PMID:38212784. |
selective serotonin reuptake inhibitors (ssris) are commonly prescribed to manage anxiety in adults with an autism diagnosis. |
2024-01-11 |
2024-01-14 |
Not clear |
| Computational And Mathematical Methods In Medicin. Retracted: Brain Network for Exploring the Change of Brain Neurotransmitter 5-Hydroxytryptamine of Autism Children by Resting-State EEG. Computational and mathematical methods in medicine. vol 2023. 2023-12-21. PMID:38124983. |
retracted: brain network for exploring the change of brain neurotransmitter 5-hydroxytryptamine of autism children by resting-state eeg. |
2023-12-21 |
2023-12-23 |
Not clear |
| Alexander Ya Rodnyy, Elena M Kondaurova, Anton S Tsybko, Nina K Popova, Dmitry A Kudlay, Vladimir S Naumenk. The brain serotonin system in autism. Reviews in the neurosciences. 2023-07-07. PMID:37415576. |
in this review, we summarize existing data on the participation of all members of the brain 5-ht system, namely, 5-ht transporter, tryptophan hydroxylase 2, maoa, and 5-ht receptors, in autism in human and various animal models. |
2023-07-07 |
2023-08-14 |
human |
| Rohit Madan, Jody Platto, Senthil Rajaram Manoharan, Varun Mong. Serotonin Syndrome with Monotherapy of Low-Dose Sertraline in an Adult Patient with Autism Spectrum Disorder. Case reports in psychiatry. vol 2023. 2023-06-16. PMID:37324173. |
serotonin syndrome with monotherapy of low-dose sertraline in an adult patient with autism spectrum disorder. |
2023-06-16 |
2023-08-14 |
Not clear |
| Rohit Madan, Jody Platto, Senthil Rajaram Manoharan, Varun Mong. Serotonin Syndrome with Monotherapy of Low-Dose Sertraline in an Adult Patient with Autism Spectrum Disorder. Case reports in psychiatry. vol 2023. 2023-06-16. PMID:37324173. |
another known fact is that elevated whole blood serotonin, or hyperserotonemia, is one of the first biomarkers identified in autism spectrum disorder and is present in more than 25% of affected children. |
2023-06-16 |
2023-08-14 |
Not clear |
| Rohit Madan, Jody Platto, Senthil Rajaram Manoharan, Varun Mong. Serotonin Syndrome with Monotherapy of Low-Dose Sertraline in an Adult Patient with Autism Spectrum Disorder. Case reports in psychiatry. vol 2023. 2023-06-16. PMID:37324173. |
this case highlights the importance of a high degree of clinical suspicion in patients even on monotherapy of selective serotonin reuptake inhibitors in therapeutic doses, especially in children and adults with autism spectrum disorder. |
2023-06-16 |
2023-08-14 |
Not clear |
| Li Xiaoxu. Correlation between 5-HT, Hcy and the incidence and severity of autism in children. Cellular and molecular biology (Noisy-le-Grand, France). vol 69. issue 1. 2023-05-22. PMID:37213157. |
correlation between 5-ht, hcy and the incidence and severity of autism in children. |
2023-05-22 |
2023-08-14 |
Not clear |
| Li Xiaoxu. Correlation between 5-HT, Hcy and the incidence and severity of autism in children. Cellular and molecular biology (Noisy-le-Grand, France). vol 69. issue 1. 2023-05-22. PMID:37213157. |
this experiment was conducted to investigate the effects of serotonin or 5-hydroxytryptamine (5-ht) and homocysteine (hcy) levels on the incidence and severity of autism in children. |
2023-05-22 |
2023-08-14 |
Not clear |
| Li Xiaoxu. Correlation between 5-HT, Hcy and the incidence and severity of autism in children. Cellular and molecular biology (Noisy-le-Grand, France). vol 69. issue 1. 2023-05-22. PMID:37213157. |
at the same time, the effects of different levels of serotonin and hcy on the severity of autism in children were compared. |
2023-05-22 |
2023-08-14 |
Not clear |
| Li Xiaoxu. Correlation between 5-HT, Hcy and the incidence and severity of autism in children. Cellular and molecular biology (Noisy-le-Grand, France). vol 69. issue 1. 2023-05-22. PMID:37213157. |
5-ht, breast feeding, hcy, vitamin b12 level, febrile convulsion and traumatic brain injury were the main risk factors for children with autism, while the psychological intervention was the main protective factor, which had a significant positive impact on the severity of children with autism (p < 0.05). |
2023-05-22 |
2023-08-14 |
Not clear |
| Li Xiaoxu. Correlation between 5-HT, Hcy and the incidence and severity of autism in children. Cellular and molecular biology (Noisy-le-Grand, France). vol 69. issue 1. 2023-05-22. PMID:37213157. |
5-ht and hcy levels have significant predictive effects on the development of children with autism and can be used as predictive indicators for the development of autism. |
2023-05-22 |
2023-08-14 |
Not clear |
| Li Xiaoxu. Correlation between 5-HT, Hcy and the incidence and severity of autism in children. Cellular and molecular biology (Noisy-le-Grand, France). vol 69. issue 1. 2023-05-22. PMID:37213157. |
in conclusion, 5-ht, feeding mode, hcy, vitamin b12 level and febrile convulsion are the main risk factors for autism in children, and there are significant correlations. |
2023-05-22 |
2023-08-14 |
Not clear |
| Sijie Chen, Longsheng Huang, Guihua Liu, Jie Kang, Qinfang Qian, Jingrong Wang, Rong Wang, Lizhen Zheng, Haijun Wang, Ping O. Acupuncture Ameliorated Behavioral Abnormalities in the Autism Rat Model via Pathways for Hippocampal Serotonin. Neuropsychiatric disease and treatment. vol 19. 2023-04-25. PMID:37096024. |
acupuncture ameliorated behavioral abnormalities in the autism rat model via pathways for hippocampal serotonin. |
2023-04-25 |
2023-08-14 |
rat |
| Ender M Coskunpinar, Seymanur Tur, Nagihan Cevher Binici, Cisel Yazan Songü. Association of GABRG3, GABRB3, HTR2A Gene Variants with Autism Spectrum Disorder. Gene. 2023-04-05. PMID:37019319. |
in this study, we focused on gamma amino butyric acid (gaba) and serotonin, which are thought to contribute to the etiology of autism; it is aimed to elucidate the mechanism of the disease by investigating variant changes in the gaba receptor subunit genes gabrb3, gabrg3 and the htr2a gene, which encodes one of the serotonin receptors. |
2023-04-05 |
2023-08-14 |
human |
| Ramesa Shafi Bhat, Mona Alonazi, Sooad Al-Daihan, Afaf El-Ansar. Prenatal SSRI Exposure Increases the Risk of Autism in Rodents via Aggravated Oxidative Stress and Neurochemical Changes in the Brain. Metabolites. vol 13. issue 2. 2023-02-25. PMID:36837929. |
the mechanisms underlying selective serotonin reuptake inhibitor (ssri) use during pregnancy as a major autism risk factor are unclear. |
2023-02-25 |
2023-08-14 |
rat |
| Barbara Carpita, Rossella Stagnari, Lionella Palego, Dario Baroni, Gabriele Massimetti, Benedetta Nardi, Ivan Mirko Cremone, Laura Betti, Gino Giannaccini, Liliana Dell'Oss. Circulating levels of 5-HT and BDNF in Adults with Autism Spectrum Conditions: an Investigation in a Sample of Subjects with Autism Spectrum Disorder, their first-degree Relatives and Controls. Current medicinal chemistry. 2023-01-31. PMID:36718970. |
circulating levels of 5-ht and bdnf in adults with autism spectrum conditions: an investigation in a sample of subjects with autism spectrum disorder, their first-degree relatives and controls. |
2023-01-31 |
2023-08-14 |
human |
| Barbara Carpita, Rossella Stagnari, Lionella Palego, Dario Baroni, Gabriele Massimetti, Benedetta Nardi, Ivan Mirko Cremone, Laura Betti, Gino Giannaccini, Liliana Dell'Oss. Circulating levels of 5-HT and BDNF in Adults with Autism Spectrum Conditions: an Investigation in a Sample of Subjects with Autism Spectrum Disorder, their first-degree Relatives and Controls. Current medicinal chemistry. 2023-01-31. PMID:36718970. |
several studies investigated circulating levels of serotonin (5-ht) and brain-derived neurotrophic factor (bdnf) in children with autism spectrum disorder (asd). |
2023-01-31 |
2023-08-14 |
human |