| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nibal Betari, Kristoffer Sahlholm, Xavier Morató, Héctor Godoy-Marín, Olga Jáuregui, Knut Teigen, Francisco Ciruela, Jan Haavi. Inhibition of Tryptophan Hydroxylases and Monoamine Oxidase-A by the Proton Pump Inhibitor, Omeprazole- Frontiers in pharmacology. vol 11. 2020-12-17. PMID:33324221. |
due to the implication of 5-ht in a number of pathologies, including depression, anxiety, autism, sexual dysfunction, irritable bowel syndrome, inflammatory bowel disease, and carcinoid syndrome, there has been a growing interest in finding modulators of these enzymes in recent years. |
2020-12-17 |
2023-08-13 |
Not clear |
| Rebecca H Lawrence, Michelle C Palumbo, Sara M Freeman, Caleigh D Guoynes, Karen L Bale. Developmental Fluoxetine Exposure Alters Behavior and Neuropeptide Receptors in the Prairie Vole. Frontiers in behavioral neuroscience. vol 14. 2020-12-12. PMID:33304247. |
developmental exposure to selective serotonin reuptake inhibitor (ssri) increases the risk of autism spectrum disorder (asd), however, the underlying neurobiology of this effect is not fully understood. |
2020-12-12 |
2023-08-13 |
Not clear |
| Jinpeng Wang, Baihong Zheng, Dan Zhou, Jie Xing, Honghua Li, Jiayu Li, Zehui Zhang, Beilin Zhang, Ping L. Supplementation of Diet With Different n-3/n-6 PUFA Ratios Ameliorates Autistic Behavior, Reduces Serotonin, and Improves Intestinal Barrier Impairments in a Valproic Acid Rat Model of Autism. Frontiers in psychiatry. vol 11. 2020-10-10. PMID:33033482. |
supplementation of diet with different n-3/n-6 pufa ratios ameliorates autistic behavior, reduces serotonin, and improves intestinal barrier impairments in a valproic acid rat model of autism. |
2020-10-10 |
2023-08-13 |
rat |
| Ismo Makkonen, Raili Riikonen, Jyrki T Kuikka, Hannu Kokki, Joseph P Bressler, Cathleen Marshall, Walter E Kaufman. Brain derived neurotrophic factor and serotonin transporter binding as markers of clinical response to fluoxetine therapy in children with autism. Journal of pediatric neurology : JPN. vol 9. issue 1. 2020-10-01. PMID:29056860. |
brain derived neurotrophic factor and serotonin transporter binding as markers of clinical response to fluoxetine therapy in children with autism. |
2020-10-01 |
2023-08-13 |
human |
| Ismo Makkonen, Raili Riikonen, Jyrki T Kuikka, Hannu Kokki, Joseph P Bressler, Cathleen Marshall, Walter E Kaufman. Brain derived neurotrophic factor and serotonin transporter binding as markers of clinical response to fluoxetine therapy in children with autism. Journal of pediatric neurology : JPN. vol 9. issue 1. 2020-10-01. PMID:29056860. |
fluoxetine, a selective serotonin reuptake inhibitor (ssri), has shown favorable effects in some children with autism. |
2020-10-01 |
2023-08-13 |
human |
| Barnali Chakraborti, Deepak Verma, Subhrangshu Guhathakurta, Preeti Jaiswal, Asem Surindro Singh, Swagata Sinha, Saurabh Ghosh, Kanchan Mukhopadhyay, Kochupurackal P Mohanakumar, Usha Rajamm. Gender-Specific Effect of 5-HT and 5-HIAA on Threshold Level of Behavioral Symptoms and Sex-Bias in Prevalence of Autism Spectrum Disorder. Frontiers in neuroscience. vol 13. 2020-09-29. PMID:31998058. |
gender-specific effect of 5-ht and 5-hiaa on threshold level of behavioral symptoms and sex-bias in prevalence of autism spectrum disorder. |
2020-09-29 |
2023-08-13 |
Not clear |
| Barnali Chakraborti, Deepak Verma, Subhrangshu Guhathakurta, Preeti Jaiswal, Asem Surindro Singh, Swagata Sinha, Saurabh Ghosh, Kanchan Mukhopadhyay, Kochupurackal P Mohanakumar, Usha Rajamm. Gender-Specific Effect of 5-HT and 5-HIAA on Threshold Level of Behavioral Symptoms and Sex-Bias in Prevalence of Autism Spectrum Disorder. Frontiers in neuroscience. vol 13. 2020-09-29. PMID:31998058. |
platelet hyperserotonemia in a subset of autism spectrum disorder (asd) probands, efficacy of selective serotonin reuptake inhibitors (ssris) in reducing behavioral deficits and gender-bias in normal serotonin (5-hydroxy tryptamine or 5-ht) synthesis suggest disruption in stringent regulation of serotonin metabolism in asd. |
2020-09-29 |
2023-08-13 |
Not clear |
| Kimberly B Schauder, Christopher L Muller, Jeremy Veenstra-VanderWeele, Carissa J Casci. Genetic Variation in Serotonin Transporter Modulates Tactile Hyperresponsiveness in ASD. Research in autism spectrum disorders. vol 10. 2020-09-28. PMID:25558276. |
several lines of evidence implicate dysfunction of the serotonin (5-ht) system in autism spectrum disorder (asd). |
2020-09-28 |
2023-08-13 |
human |
| Carsten A Raabe, Reinhard Voss, Delf-Magnus Kummerfeld, Juergen Brosius, Chenna R Galiveti, Anna Wolters, Jochen Seggewiss, Andreas Huge, Boris V Skryabin, Timofey S Rozhdestvensk. Ectopic expression of Snord115 in choroid plexus interferes with editing but not splicing of 5-Ht2c receptor pre-mRNA in mice. Scientific reports. vol 9. issue 1. 2020-09-28. PMID:30862860. |
serotonin 5-ht2c receptor is a g-protein coupled excitatory receptor that regulates several biochemical pathways and has been implicated in obesity, mental state, sleep cycles, autism, neuropsychiatric disorders and neurodegenerative diseases. |
2020-09-28 |
2023-08-13 |
mouse |
| Rosa Marotta, Maria C Risoleo, Giovanni Messina, Lucia Parisi, Marco Carotenuto, Luigi Vetri, Michele Roccell. The Neurochemistry of Autism. Brain sciences. vol 10. issue 3. 2020-09-28. PMID:32182969. |
in this review, we aim to delineate the state-of-the-art main research findings about the neurochemical alterations in autism etiology, and focuses on gamma aminobutyric acid (gaba) and glutamate, serotonin, dopamine, n-acetyl aspartate, oxytocin and arginine-vasopressin, melatonin, vitamin d, orexin, endogenous opioids, and acetylcholine. |
2020-09-28 |
2023-08-13 |
Not clear |
| Reem Rafik Alolaby, Poonnada Jiraanont, Blythe Durbin-Johnson, Mittal Jasoliya, Hiu-Tung Tang, Randi Hagerman, Flora Tasson. Molecular Biomarkers Predictive of Sertraline Treatment Response in Young Children With Autism Spectrum Disorder. Frontiers in genetics. vol 11. 2020-09-28. PMID:32346385. |
sertraline is one among several selective serotonin reuptake inhibitors (ssris) that exhibited improvement of language development in autism spectrum disorder (asd); however, the molecular mechanism has not been elucidated. |
2020-09-28 |
2023-08-13 |
human |
| Meagan A Quinlan, Matthew J Robson, Ran Ye, Kristie L Rose, Kevin L Schey, Randy D Blakel. Frontiers in molecular neuroscience. vol 13. 2020-09-28. PMID:32581705. |
altered serotonin (5-ht) signaling is associated with multiple brain disorders, including major depressive disorder (mdd), obsessive-compulsive disorder (ocd), and autism spectrum disorder (asd). |
2020-09-28 |
2023-08-13 |
human |
| Wikrom Wongpaiboonwattana, Oradawan Plong-On, Areerat Hnoonual, Pornprot Limpraser. Significant associations between 5-hydroxytryptaminetransporter-linked promoter region polymorphisms of the serotonin transporter (solute carrier family 6 member 4) gene and Thai patients with autism spectrum disorder. Medicine. vol 99. issue 36. 2020-09-24. PMID:32899028. |
significant associations between 5-hydroxytryptaminetransporter-linked promoter region polymorphisms of the serotonin transporter (solute carrier family 6 member 4) gene and thai patients with autism spectrum disorder. |
2020-09-24 |
2023-08-13 |
Not clear |
| Erica L Smearman, Cassandra L Hendrix, Dominika A Winiarski, Katrina C Johnson, Alicia K Smith, Opal Y Ousley, Zachary N Stowe, D Jeffrey Newport, Patricia A Brenna. School-age social behavior and pragmatic language ability in children with prenatal serotonin reuptake inhibitor exposure. Development and psychopathology. vol 32. issue 1. 2020-08-25. PMID:30728091. |
studies examining associations between fetal serotonin reuptake inhibitor (sri) exposure and child autism spectrum disorder (asd) diagnoses or delayed language remain mixed and rarely prospectively follow children or employ gold-standard assessments. |
2020-08-25 |
2023-08-13 |
Not clear |
| Gregory Thorkelson, Sarah F Laughlin, Kylan S Turner, Nicole Ober, Benjamin L Hande. Selective Serotonin Reuptake Inhibitor Monotherapy for Anxiety Disorders in Children and Adolescents with Autism Spectrum Disorder: A Chart Review. Journal of child and adolescent psychopharmacology. vol 29. issue 9. 2020-08-18. PMID:31295004. |
selective serotonin reuptake inhibitor monotherapy for anxiety disorders in children and adolescents with autism spectrum disorder: a chart review. |
2020-08-18 |
2023-08-13 |
Not clear |
| Robert H Wichers, James L Findon, Auke Jelsma, Vincent Giampietro, Vladimira Stoencheva, Dene M Robertson, Clodagh M Murphy, Grainne McAlonan, Christine Ecker, Katya Rubia, Declan G M Murphy, Eileen M Dal. Modulation of brain activation during executive functioning in autism with citalopram. Translational psychiatry. vol 9. issue 1. 2020-08-05. PMID:31712584. |
adults with autism spectrum disorder (asd) are frequently prescribed selective serotonin reuptake inhibitors (ssris). |
2020-08-05 |
2023-08-13 |
Not clear |
| Nurdan Coban, Cem Gokcen, Sinan Akbayram, Baran Calisga. Evaluation of Platelet Parameters in Children with Autism Spectrum Disorder: Elongated Collagen-Adenosine Diphosphate and Collagen-Epinephrine Closure Times. Autism research : official journal of the International Society for Autism Research. vol 12. issue 7. 2020-07-28. PMID:31077574. |
© 2019 international society for autism research, wiley periodicals, inc. lay summary: serotonin is a chemical that is found in brain as wells as in blood cells that function in blood clotting in the human body. |
2020-07-28 |
2023-08-13 |
human |
| Nurdan Coban, Cem Gokcen, Sinan Akbayram, Baran Calisga. Evaluation of Platelet Parameters in Children with Autism Spectrum Disorder: Elongated Collagen-Adenosine Diphosphate and Collagen-Epinephrine Closure Times. Autism research : official journal of the International Society for Autism Research. vol 12. issue 7. 2020-07-28. PMID:31077574. |
there are problems related to serotonin in brains of people who have autism. |
2020-07-28 |
2023-08-13 |
human |
| Michael Maes, George Anderson, Susana R Betancort Medina, Moonsang Seo, Johanna O Ojal. Integrating Autism Spectrum Disorder Pathophysiology: Mitochondria, Vitamin A, CD38, Oxytocin, Serotonin and Melatonergic Alterations in the Placenta and Gut. Current pharmaceutical design. vol 25. issue 41. 2020-06-17. PMID:31682209. |
integrating autism spectrum disorder pathophysiology: mitochondria, vitamin a, cd38, oxytocin, serotonin and melatonergic alterations in the placenta and gut. |
2020-06-17 |
2023-08-13 |
Not clear |
| Cheryl Brandenburg, Gene J Blat. Differential serotonin transporter (5-HTT) and 5-HT Journal of neurochemistry. vol 151. issue 5. 2020-06-15. PMID:31325179. |
differential serotonin transporter (5-htt) and 5-ht as selective serotonin reuptake inhibitors (ssris) are among the most commonly prescribed medications in autism, we aimed to determine whether targets for ssris are differentially affected in three cortical areas in children and adults with autism compared to neurotypical individuals. |
2020-06-15 |
2023-08-13 |
Not clear |