All Relations between Autism Spectrum Disorder and serotonin

Publication Sentence Publish Date Extraction Date Species
Valentina R Garbarino, T Lee Gilman, Lynette C Daws, Georgianna G Goul. Extreme enhancement or depletion of serotonin transporter function and serotonin availability in autism spectrum disorder. Pharmacological research. vol 140. 2019-05-13. PMID:30009933. this review will summarize key aspects of central 5-ht function important for normal brain development, and review evidence implicating perinatal disruptions in 5-ht signaling in the pathophysiology of autism spectrum disorder. 2019-05-13 2023-08-13 human
Valentina R Garbarino, T Lee Gilman, Lynette C Daws, Georgianna G Goul. Extreme enhancement or depletion of serotonin transporter function and serotonin availability in autism spectrum disorder. Pharmacological research. vol 140. 2019-05-13. PMID:30009933. we discuss the importance, and relative dearth, of studies that explore the possible correlation to autism in the interactions between important intrinsic and extrinsic factors that may disrupt 5-ht homeostasis during development. 2019-05-13 2023-08-13 human
Valentina R Garbarino, T Lee Gilman, Lynette C Daws, Georgianna G Goul. Extreme enhancement or depletion of serotonin transporter function and serotonin availability in autism spectrum disorder. Pharmacological research. vol 140. 2019-05-13. PMID:30009933. we postulate that extreme bidirectional perturbations of these factors during development likely compound or synergize to facilitate enduring neurochemical changes resulting in insufficient or excessive 5-ht signaling, that could underlie the persistent behavioral characteristics of autism spectrum disorder. 2019-05-13 2023-08-13 human
Ze-Ya Shi, Ya-Min L. Association Between Antenatal Exposure to Selective Serotonin Reuptake Inhibitors and Autism: A Need for Further Analysis. The Journal of clinical psychiatry. vol 78. issue 7. 2019-03-22. PMID:28858446. association between antenatal exposure to selective serotonin reuptake inhibitors and autism: a need for further analysis. 2019-03-22 2023-08-13 Not clear
Calvin P Sjaarda, Patrick Hecht, Amy J M McNaughton, Audrina Zhou, Melissa L Hudson, Matt J Will, Garth Smith, Muhammad Ayub, Ping Liang, Nansheng Chen, David Beversdorf, Xudong Li. Interplay between maternal Slc6a4 mutation and prenatal stress: a possible mechanism for autistic behavior development. Scientific reports. vol 7. issue 1. 2019-03-15. PMID:28821725. the low activity allele of the maternal polymorphism, 5httlpr, in the serotonin transporter, slc6a4, coupled with prenatal stress is reported to increase the risk for children to develop autism spectrum disorder (asd). 2019-03-15 2023-08-13 mouse
Jian-Jun Ou, Ya-Min L. Autism spectrum disorder and prenatal exposure to selective serotonin reuptake inhibitors: Need for further analysis. Reproductive toxicology (Elmsford, N.Y.). vol 67. 2019-03-06. PMID:27915014. autism spectrum disorder and prenatal exposure to selective serotonin reuptake inhibitors: need for further analysis. 2019-03-06 2023-08-13 Not clear
Jessica J Walsh, Daniel J Christoffel, Boris D Heifets, Gabriel A Ben-Dor, Aslihan Selimbeyoglu, Lin W Hung, Karl Deisseroth, Robert C Malenk. 5-HT release in nucleus accumbens rescues social deficits in mouse autism model. Nature. vol 560. issue 7720. 2019-03-04. PMID:30089910. 5-ht release in nucleus accumbens rescues social deficits in mouse autism model. 2019-03-04 2023-08-13 mouse
Susan E Maloney, Shyam Akula, Michael A Rieger, Katherine B McCullough, Krystal Chandler, Adrian M Corbett, Audrey E McGowin, Joseph D Doughert. Examining the Reversibility of Long-Term Behavioral Disruptions in Progeny of Maternal SSRI Exposure. eNeuro. vol 5. issue 4. 2019-02-27. PMID:30073191. epidemiological studies have examined association between selective serotonin reuptake inhibitor (ssri) treatment during pregnancy and increased autism spectrum disorder (asd) risk in offspring. 2019-02-27 2023-08-13 Not clear
Reham Shehabeldin, David Lutz, Meliha Karsak, Michael Frotscher, Kerstin Krieglstein, Ahmed Shara. Reelin controls the positioning of brainstem serotonergic raphe neurons. PloS one. vol 13. issue 7. 2019-01-02. PMID:30001399. dysregulation of serotonin signaling during critical periods is involved in developmental neurological disorders, such as schizophrenia and autism. 2019-01-02 2023-08-13 Not clear
Han-Fang Wu, Yi-Ju Chen, Ming-Chia Chu, Ya-Ting Hsu, Ting-Yi Lu, I-Tuan Chen, Po See Chen, Hui-Ching Li. Deep Brain Stimulation Modified Autism-Like Deficits via the Serotonin System in a Valproic Acid-Induced Rat Model. International journal of molecular sciences. vol 19. issue 9. 2018-12-18. PMID:30235871. previous study revealed that dysfunction of brain 5-ht homeostasis is related to a valproate (vpa)-induced rat autism spectrum disorder (asd) model. 2018-12-18 2023-08-13 rat
Jacob Ellegood, Yohan Yee, Travis M Kerr, Christopher L Muller, Randy D Blakely, R Mark Henkelman, Jeremy Veenstra-VanderWeele, Jason P Lerc. Analysis of neuroanatomical differences in mice with genetically modified serotonin transporters assessed by structural magnetic resonance imaging. Molecular autism. vol 9. 2018-10-24. PMID:29651330. the serotonin (5-ht) system has long been implicated in autism spectrum disorder (asd) as indicated by elevated whole blood and platelet 5-ht, altered platelet and brain receptor and transporter binding, and genetic linkage and association findings. 2018-10-24 2023-08-13 mouse
Haidar A Abdulamir, Omar F Abdul-Rasheed, Emad A Abdulghan. Serotonin and serotonin transporter levels in autistic children. Saudi medical journal. vol 39. issue 5. 2018-10-24. PMID:29738009. to assess the possible correlation between serotonin and serotonin transporter (sert) with the autism severity and investigate the association between these parameters in autistic children to assess their possible role for diagnosis of autism severity. 2018-10-24 2023-08-13 Not clear
Sorayya Kheirouri, Parinaz Kalejahi, Seyyed Gholamreza Nooraza. Plasma levels of serotonin, gastrointestinal symptoms,and sleep problems in children with autism. Turkish journal of medical sciences. vol 46. issue 6. 2018-09-20. PMID:28081325. plasma levels of serotonin, gastrointestinal symptoms,and sleep problems in children with autism. 2018-09-20 2023-08-13 Not clear
Sorayya Kheirouri, Parinaz Kalejahi, Seyyed Gholamreza Nooraza. Plasma levels of serotonin, gastrointestinal symptoms,and sleep problems in children with autism. Turkish journal of medical sciences. vol 46. issue 6. 2018-09-20. PMID:28081325. autism is a neurodevelopmental disorder identified with higher frequency of serotonin abnormalities and gastrointestinal (gi) and sleep problems. 2018-09-20 2023-08-13 Not clear
Sorayya Kheirouri, Parinaz Kalejahi, Seyyed Gholamreza Nooraza. Plasma levels of serotonin, gastrointestinal symptoms,and sleep problems in children with autism. Turkish journal of medical sciences. vol 46. issue 6. 2018-09-20. PMID:28081325. this study aimed to evaluate the plasma levels of serotonin, gi symptoms, and sleep problems, and their relationship with autism severity in children with autism. 2018-09-20 2023-08-13 Not clear
Lauritz R Meyer, Benjamin Dexter, Cecilia Lo, Elizabeth Kenkel, Takahito Hirai, Robert D Roghair, Sarah E Haskel. Perinatal SSRI exposure permanently alters cerebral serotonin receptor mRNA in mice but does not impact adult behaviors. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians. vol 31. issue 11. 2018-09-14. PMID:28385052. associations have been made between maternal selective serotonin reuptake inhibitor (ssri) use during pregnancy and altered behavior in offspring, including an increased risk of autism. 2018-09-14 2023-08-13 mouse
Mohamed Abdulkadir, Douglas Londono, Derek Gordon, Thomas V Fernandez, Lawrence W Brown, Keun-Ah Cheon, Barbara J Coffey, Lonneke Elzerman, Carolin Fremer, Odette Fründt, Blanca Garcia-Delgar, Donald L Gilbert, Dorothy E Grice, Tammy Hedderly, Isobel Heyman, Hyun Ju Hong, Chaim Huyser, Laura Ibanez-Gomez, Ewgeni Jakubovski, Young Key Kim, Young Shin Kim, Yun-Joo Koh, Sodahm Kook, Samuel Kuperman, Bennett Leventhal, Andrea G Ludolph, Marcos Madruga-Garrido, Athanasios Maras, Pablo Mir, Astrid Morer, Kirsten Müller-Vahl, Alexander Münchau, Tara L Murphy, Kerstin J Plessen, Veit Roessner, Eun-Young Shin, Dong-Ho Song, Jungeun Song, Jennifer Tübing, Els van den Ban, Frank Visscher, Sina Wanderer, Martin Woods, Samuel H Zinner, Robert A King, Jay A Tischfield, Gary A Heiman, Pieter J Hoekstra, Andrea Dietric. Investigation of previously implicated genetic variants in chronic tic disorders: a transmission disequilibrium test approach. European archives of psychiatry and clinical neuroscience. vol 268. issue 3. 2018-09-11. PMID:28555406. 17 were candidate snps implicated in ts and 2 were implicated in obsessive-compulsive disorder (ocd) or autism spectrum disorder (asd); 142 were tagging snps from eight monoamine neurotransmitter-related genes (including dopamine and serotonin); 10 were top snps from ts gwas; and 13 top snps from attention-deficit/hyperactivity disorder, ocd, or asd gwas. 2018-09-11 2023-08-13 Not clear
Min Guo, Jiang Zhu, Ting Yang, Xi Lai, Xiao Liu, Juan Liu, Jie Chen, Tingyu L. Vitamin A improves the symptoms of autism spectrum disorders and decreases 5-hydroxytryptamine (5-HT): A pilot study. Brain research bulletin. vol 137. 2018-08-31. PMID:29122693. many studies have demonstrated that children with autism have multiple nutritional deficiencies and increased serum 5-hydroxytryptamine (5-ht) levels. 2018-08-31 2023-08-13 Not clear
Min Guo, Jiang Zhu, Ting Yang, Xi Lai, Xiao Liu, Juan Liu, Jie Chen, Tingyu L. Vitamin A improves the symptoms of autism spectrum disorders and decreases 5-hydroxytryptamine (5-HT): A pilot study. Brain research bulletin. vol 137. 2018-08-31. PMID:29122693. serum 5-ht levels in children with asd were higher than in control children, which were correlated with symptom severity of children with autism. 2018-08-31 2023-08-13 Not clear
Min Guo, Jiang Zhu, Ting Yang, Xi Lai, Xiao Liu, Juan Liu, Jie Chen, Tingyu L. Vitamin A improves the symptoms of autism spectrum disorders and decreases 5-hydroxytryptamine (5-HT): A pilot study. Brain research bulletin. vol 137. 2018-08-31. PMID:29122693. this study suggested that va supplementation may improve symptoms and reduce 5-ht levels in children with asd, indicating that va supplementation is a reasonable therapy at least for a subset of children with autism. 2018-08-31 2023-08-13 Not clear