| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jenna L N Sprowles, Jillian R Hufgard, Arnold Gutierrez, Rebecca A Bailey, Sarah A Jablonski, Michael T Williams, Charles V Vorhee. Perinatal exposure to the selective serotonin reuptake inhibitor citalopram alters spatial learning and memory, anxiety, depression, and startle in Sprague-Dawley rats. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 54. 2017-03-27. PMID:27591973. |
prenatal ssri exposure has been associated with an increased prevalence of autism spectrum disorder (asd), and peripheral 5-ht is elevated in some asd patients. |
2017-03-27 |
2023-08-13 |
rat |
| Dubravka Hranilovic, Sofia Blazevic, Jasminka Stefulj, Peter Zil. DNA Methylation Analysis of HTR2A Regulatory Region in Leukocytes of Autistic Subjects. Autism research : official journal of the International Society for Autism Research. vol 9. issue 2. 2017-01-11. PMID:26149086. |
disturbed brain and peripheral serotonin homeostasis is often found in subjects with autism spectrum disorder (asd). |
2017-01-11 |
2023-08-13 |
human |
| Dubravka Hranilovic, Sofia Blazevic, Jasminka Stefulj, Peter Zil. DNA Methylation Analysis of HTR2A Regulatory Region in Leukocytes of Autistic Subjects. Autism research : official journal of the International Society for Autism Research. vol 9. issue 2. 2017-01-11. PMID:26149086. |
the role of the serotonin receptor 2a (htr2a) in the regulation of central and peripheral serotonin homeostasis, as well as its altered expression in autistic subjects, have implicated the htr2a gene as a major candidate for the serotonin disturbance seen in autism. |
2017-01-11 |
2023-08-13 |
human |
| Tina J Walch, Amanda Tinkelma. Selective Serotonin Reuptake Inhibitors and Autism. American journal of therapeutics. vol 23. issue 2. 2016-12-20. PMID:26950585. |
selective serotonin reuptake inhibitors and autism. |
2016-12-20 |
2023-08-13 |
Not clear |
| C L Muller, A M J Anacker, J Veenstra-VanderWeel. The serotonin system in autism spectrum disorder: From biomarker to animal models. Neuroscience. vol 321. 2016-12-13. PMID:26577932. |
elevated whole blood serotonin, or hyperserotonemia, was the first biomarker identified in autism spectrum disorder (asd) and is present in more than 25% of affected children. |
2016-12-13 |
2023-08-13 |
mouse |
| Sarah Marler, Bradley J Ferguson, Evon Batey Lee, Brittany Peters, Kent C Williams, Erin McDonnell, Eric A Macklin, Pat Levitt, Catherine Hagan Gillespie, George M Anderson, Kara Gross Margolis, David Q Beversdorf, Jeremy Veenstra-VanderWeel. Brief Report: Whole Blood Serotonin Levels and Gastrointestinal Symptoms in Autism Spectrum Disorder. Journal of autism and developmental disorders. vol 46. issue 3. 2016-09-27. PMID:26527110. |
brief report: whole blood serotonin levels and gastrointestinal symptoms in autism spectrum disorder. |
2016-09-27 |
2023-08-13 |
Not clear |
| Sarah Marler, Bradley J Ferguson, Evon Batey Lee, Brittany Peters, Kent C Williams, Erin McDonnell, Eric A Macklin, Pat Levitt, Catherine Hagan Gillespie, George M Anderson, Kara Gross Margolis, David Q Beversdorf, Jeremy Veenstra-VanderWeel. Brief Report: Whole Blood Serotonin Levels and Gastrointestinal Symptoms in Autism Spectrum Disorder. Journal of autism and developmental disorders. vol 46. issue 3. 2016-09-27. PMID:26527110. |
elevated whole blood serotonin levels are observed in more than 25% of children with autism spectrum disorder (asd). |
2016-09-27 |
2023-08-13 |
Not clear |
| Diane C Chugani, Harry T Chugani, Max Wiznitzer, Sumit Parikh, Patricia A Evans, Robin L Hansen, Ruth Nass, James J Janisse, Pamela Dixon-Thomas, Michael Behen, Robert Rothermel, Jacqueline S Parker, Ajay Kumar, Otto Muzik, David J Edwards, Deborah Hirt. Efficacy of Low-Dose Buspirone for Restricted and Repetitive Behavior in Young Children with Autism Spectrum Disorder: A Randomized Trial. The Journal of pediatrics. vol 170. 2016-07-26. PMID:26746121. |
to determine safety and efficacy of the 5ht1a serotonin partial agonist buspirone on core autism and associated features in children with autism spectrum disorder (asd). |
2016-07-26 |
2023-08-13 |
Not clear |
| Gül Döle. Autism: Oxytocin, serotonin, and social reward. Social neuroscience. vol 10. issue 5. 2016-07-22. PMID:26317636. |
autism: oxytocin, serotonin, and social reward. |
2016-07-22 |
2023-08-13 |
Not clear |
| N L Baganz, K M Lindler, C B Zhu, J T Smith, M J Robson, H Iwamoto, E S Deneris, W A Hewlett, R D Blakel. A requirement of serotonergic p38α mitogen-activated protein kinase for peripheral immune system activation of CNS serotonin uptake and serotonin-linked behaviors. Translational psychiatry. vol 5. 2016-07-19. PMID:26529424. |
alterations in central serotonin (5-hydroxytryptamine, 5-ht) neurotransmission and peripheral immune activation have been linked to multiple neuropsychiatric disorders, including depression, schizophrenia and autism. |
2016-07-19 |
2023-08-13 |
mouse |
| Jeffrey R Bishop, Fedra Najjar, Leah H Rubin, Stephen J Guter, Thomas Owley, Matthew W Mosconi, Suma Jacob, Edwin H Coo. Escitalopram pharmacogenetics: CYP2C19 relationships with dosing and clinical outcomes in autism spectrum disorder. Pharmacogenetics and genomics. vol 25. issue 11. 2016-07-11. PMID:26313485. |
selective serotonin reuptake inhibitors such as escitalopram are commonly used to treat patients with autism spectrum disorder (asd), but there are individual differences in treatment response and tolerability. |
2016-07-11 |
2023-08-13 |
Not clear |
| Lars Henning Pederse. Prenatal Antidepressant Exposure and Childhood Autism Spectrum Disorders: Cause for Concern? Paediatric drugs. vol 17. issue 6. 2016-07-01. PMID:26092083. |
there is empirical evidence for a role for serotonin in autism . |
2016-07-01 |
2023-08-13 |
Not clear |
| Cristina Viaggi, Claudio Gerace, Carla Pardini, Giovanni U Corsini, Francesca Vaglin. Serotonin abnormalities in Engrailed-2 knockout mice: New insight relevant for a model of Autism Spectrum Disorder. Neurochemistry international. vol 87. 2016-05-24. PMID:26002543. |
serotonin abnormalities in engrailed-2 knockout mice: new insight relevant for a model of autism spectrum disorder. |
2016-05-24 |
2023-08-13 |
mouse |
| Fedra Najjar, Thomas Owley, Matthew W Mosconi, Suma Jacob, Kwan Hur, Stephen J Guter, John A Sweeney, Robert D Gibbons, Edwin H Cook, Jeffrey R Bisho. Pharmacogenetic Study of Serotonin Transporter and 5HT2A Genotypes in Autism. Journal of child and adolescent psychopharmacology. vol 25. issue 6. 2016-05-19. PMID:26262902. |
pharmacogenetic study of serotonin transporter and 5ht2a genotypes in autism. |
2016-05-19 |
2023-08-13 |
Not clear |
| Fedra Najjar, Thomas Owley, Matthew W Mosconi, Suma Jacob, Kwan Hur, Stephen J Guter, John A Sweeney, Robert D Gibbons, Edwin H Cook, Jeffrey R Bisho. Pharmacogenetic Study of Serotonin Transporter and 5HT2A Genotypes in Autism. Journal of child and adolescent psychopharmacology. vol 25. issue 6. 2016-05-19. PMID:26262902. |
the purpose of this study was to determine whether polymorphisms in the serotonin transporter (slc6a4) and serotonin-2a receptor (htr2a) genes are associated with response to escitalopram in patients with autism spectrum disorder (asd). |
2016-05-19 |
2023-08-13 |
Not clear |
| C-J Yang, C-L Liu, B Sang, X-M Zhu, Y-J D. The combined role of serotonin and interleukin-6 as biomarker for autism. Neuroscience. vol 284. 2015-12-22. PMID:25453766. |
the combined role of serotonin and interleukin-6 as biomarker for autism. |
2015-12-22 |
2023-08-13 |
Not clear |
| C-J Yang, C-L Liu, B Sang, X-M Zhu, Y-J D. The combined role of serotonin and interleukin-6 as biomarker for autism. Neuroscience. vol 284. 2015-12-22. PMID:25453766. |
it has been shown that dysfunction of serotonin (5-ht) and interleukin-6 (il-6) are involved in autism. |
2015-12-22 |
2023-08-13 |
Not clear |
| C-J Yang, C-L Liu, B Sang, X-M Zhu, Y-J D. The combined role of serotonin and interleukin-6 as biomarker for autism. Neuroscience. vol 284. 2015-12-22. PMID:25453766. |
the goal of this study was to evaluate the combined role of 5-ht and il-6 as potential biomarkers for autism. |
2015-12-22 |
2023-08-13 |
Not clear |
| C-J Yang, C-L Liu, B Sang, X-M Zhu, Y-J D. The combined role of serotonin and interleukin-6 as biomarker for autism. Neuroscience. vol 284. 2015-12-22. PMID:25453766. |
the whole blood concentration of 5-ht and plasma concentration of il-6 of individuals with autism were significantly elevated compared with the control group, and the concentration of 5-ht and il-6 had positive correlations with the severity of autism. |
2015-12-22 |
2023-08-13 |
Not clear |
| C-J Yang, C-L Liu, B Sang, X-M Zhu, Y-J D. The combined role of serotonin and interleukin-6 as biomarker for autism. Neuroscience. vol 284. 2015-12-22. PMID:25453766. |
the results of receiver operating characteristic (roc) analysis indicated that the combination of 5-ht and il-6 produced the best sensitivity and specificity for diagnosis of autism. |
2015-12-22 |
2023-08-13 |
Not clear |