| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Anna Bochyńska, Grzegorz Witkowski, Magdalena Gugała-Iwaniuk, Danuta Ryglewicz, Halina Sienkiewicz-Jaros. Volume changes of medial temporal lobe structures in patients with genetic generalized and temporal lobe epilepsy in relation to neuropsychological functions. Postepy psychiatrii neurologii. vol 31. issue 4. 2023-04-21. PMID:37081908. |
the aim of the study was to compare the volume of the hippocampus (vhip), amygdala (vamg) and parahippocampal gyrus (vphg) with the results of neuropsychological assessment in patients with temporal lobe epilepsy (tle) and genetic generalized epilepsy (gge). |
2023-04-21 |
2023-08-14 |
Not clear |
| João Chaves, Bárbara Leal, Ana Sardoeira, Vanessa Carvalho, Raquel Samões, Joel Freitas, Rui Chorão, Ana Marta Ferreira, Sandra Brás, João Lopes, João Ramalheira, Carolina Lemos, Paulo Pinho Costa, António Marinho, Berta Martins da Silva, António Martins da Silv. Different relationships between epilepsy syndromes and autoimmune diseases. Epileptic disorders : international epilepsy journal with videotape. 2023-04-01. PMID:37002555. |
our objective was to study the relationship between epilepsy and autoimmune diseases in two different types of epilepsy: idiopathic generalized epilepsies (iges) and mesial temporal lobe epilepsy with hippocampal sclerosis (mtle-hs). |
2023-04-01 |
2023-08-14 |
human |
| Dalma Tényi, Tamás Tényi, Györgyi Csábi, Sára Jeges, Beáta Bóné, Katalin Lőrincz, Norbert Kovács, József Janszk. Increased prevalence of minor physical anomalies in patients with epilepsy. Scientific reports. vol 12. issue 1. 2022-08-12. PMID:35962048. |
235 patients were included, according to the following subgroups: acquired epilepsy (non-genetic, non-developmental etiology) [n = 63], temporal lobe epilepsy with hippocampal sclerosis (tle with hs) [n = 27], epilepsy with cortical dysgenesis etiology [n = 29], cryptogenic epilepsy [n = 69] and idiopathic generalized epilepsy (ige) [n = 47]. |
2022-08-12 |
2023-08-14 |
human |
| Sara Larivière, Jessica Royer, Raúl Rodríguez-Cruces, Casey Paquola, Maria Eugenia Caligiuri, Antonio Gambardella, Luis Concha, Simon S Keller, Fernando Cendes, Clarissa L Yasuda, Leonardo Bonilha, Ezequiel Gleichgerrcht, Niels K Focke, Martin Domin, Felix von Podewills, Soenke Langner, Christian Rummel, Roland Wiest, Pascal Martin, Raviteja Kotikalapudi, Terence J O'Brien, Benjamin Sinclair, Lucy Vivash, Patricia M Desmond, Elaine Lui, Anna Elisabetta Vaudano, Stefano Meletti, Manuela Tondelli, Saud Alhusaini, Colin P Doherty, Gianpiero L Cavalleri, Norman Delanty, Reetta Kälviäinen, Graeme D Jackson, Magdalena Kowalczyk, Mario Mascalchi, Mira Semmelroch, Rhys H Thomas, Hamid Soltanian-Zadeh, Esmaeil Davoodi-Bojd, Junsong Zhang, Gavin P Winston, Aoife Griffin, Aditi Singh, Vijay K Tiwari, Barbara A K Kreilkamp, Matteo Lenge, Renzo Guerrini, Khalid Hamandi, Sonya Foley, Theodor Rüber, Bernd Weber, Chantal Depondt, Julie Absil, Sarah J A Carr, Eugenio Abela, Mark P Richardson, Orrin Devinsky, Mariasavina Severino, Pasquale Striano, Domenico Tortora, Erik Kaestner, Sean N Hatton, Sjoerd B Vos, Lorenzo Caciagli, John S Duncan, Christopher D Whelan, Paul M Thompson, Sanjay M Sisodiya, Andrea Bernasconi, Angelo Labate, Carrie R McDonald, Neda Bernasconi, Boris C Bernhard. Structural network alterations in focal and generalized epilepsy assessed in a worldwide ENIGMA study follow axes of epilepsy risk gene expression. Nature communications. vol 13. issue 1. 2022-07-27. PMID:35896547. |
syndrome-specific topological alterations reflected expression patterns of risk genes for hippocampal sclerosis in tle and for generalized epilepsy in ige. |
2022-07-27 |
2023-08-14 |
Not clear |
| Michelle Guignet, Amanda Campbell, H Steve Whit. Cenobamate (XCOPRI): Can preclinical and clinical evidence provide insight into its mechanism of action? Epilepsia. vol 61. issue 11. 2021-02-03. PMID:33063849. |
cbm's preclinical performance in tests, including the mouse 6-hz model of treatment-resistant seizures, the chemoconvulsant seizure models of generalized epilepsy, and the rat hippocampal kindling model of focal epilepsy, was distinct from other voltage-gated sodium channel blockers and gaba |
2021-02-03 |
2023-08-13 |
mouse |
| Sean N Hatton, Khoa H Huynh, Leonardo Bonilha, Eugenio Abela, Saud Alhusaini, Andre Altmann, Marina K M Alvim, Akshara R Balachandra, Emanuele Bartolini, Benjamin Bender, Neda Bernasconi, Andrea Bernasconi, Boris Bernhardt, Núria Bargallo, Benoit Caldairou, Maria E Caligiuri, Sarah J A Carr, Gianpiero L Cavalleri, Fernando Cendes, Luis Concha, Esmaeil Davoodi-Bojd, Patricia M Desmond, Orrin Devinsky, Colin P Doherty, Martin Domin, John S Duncan, Niels K Focke, Sonya F Foley, Antonio Gambardella, Ezequiel Gleichgerrcht, Renzo Guerrini, Khalid Hamandi, Akari Ishikawa, Simon S Keller, Peter V Kochunov, Raviteja Kotikalapudi, Barbara A K Kreilkamp, Patrick Kwan, Angelo Labate, Soenke Langner, Matteo Lenge, Min Liu, Elaine Lui, Pascal Martin, Mario Mascalchi, José C V Moreira, Marcia E Morita-Sherman, Terence J O'Brien, Heath R Pardoe, José C Pariente, Letícia F Ribeiro, Mark P Richardson, Cristiane S Rocha, Raúl Rodríguez-Cruces, Felix Rosenow, Mariasavina Severino, Benjamin Sinclair, Hamid Soltanian-Zadeh, Pasquale Striano, Peter N Taylor, Rhys H Thomas, Domenico Tortora, Dennis Velakoulis, Annamaria Vezzani, Lucy Vivash, Felix von Podewils, Sjoerd B Vos, Bernd Weber, Gavin P Winston, Clarissa L Yasuda, Alyssa H Zhu, Paul M Thompson, Christopher D Whelan, Neda Jahanshad, Sanjay M Sisodiya, Carrie R McDonal. White matter abnormalities across different epilepsy syndromes in adults: an ENIGMA-Epilepsy study. Brain : a journal of neurology. vol 143. issue 8. 2020-12-30. PMID:32814957. |
diffusion-weighted mri data were analysed from 1069 healthy controls and 1249 patients: temporal lobe epilepsy with hippocampal sclerosis (n = 599), temporal lobe epilepsy with normal mri (n = 275), genetic generalized epilepsy (n = 182) and non-lesional extratemporal epilepsy (n = 193). |
2020-12-30 |
2023-08-13 |
human |
| Christopher D Whelan, Andre Altmann, Juan A Botía, Neda Jahanshad, Derrek P Hibar, Julie Absil, Saud Alhusaini, Marina K M Alvim, Pia Auvinen, Emanuele Bartolini, Felipe P G Bergo, Tauana Bernardes, Karen Blackmon, Barbara Braga, Maria Eugenia Caligiuri, Anna Calvo, Sarah J Carr, Jian Chen, Shuai Chen, Andrea Cherubini, Philippe David, Martin Domin, Sonya Foley, Wendy França, Gerrit Haaker, Dmitry Isaev, Simon S Keller, Raviteja Kotikalapudi, Magdalena A Kowalczyk, Ruben Kuzniecky, Soenke Langner, Matteo Lenge, Kelly M Leyden, Min Liu, Richard Q Loi, Pascal Martin, Mario Mascalchi, Marcia E Morita, Jose C Pariente, Raul Rodríguez-Cruces, Christian Rummel, Taavi Saavalainen, Mira K Semmelroch, Mariasavina Severino, Rhys H Thomas, Manuela Tondelli, Domenico Tortora, Anna Elisabetta Vaudano, Lucy Vivash, Felix von Podewils, Jan Wagner, Bernd Weber, Yi Yao, Clarissa L Yasuda, Guohao Zhang, Nuria Bargalló, Benjamin Bender, Neda Bernasconi, Andrea Bernasconi, Boris C Bernhardt, Ingmar Blümcke, Chad Carlson, Gianpiero L Cavalleri, Fernando Cendes, Luis Concha, Norman Delanty, Chantal Depondt, Orrin Devinsky, Colin P Doherty, Niels K Focke, Antonio Gambardella, Renzo Guerrini, Khalid Hamandi, Graeme D Jackson, Reetta Kälviäinen, Peter Kochunov, Patrick Kwan, Angelo Labate, Carrie R McDonald, Stefano Meletti, Terence J O'Brien, Sebastien Ourselin, Mark P Richardson, Pasquale Striano, Thomas Thesen, Roland Wiest, Junsong Zhang, Annamaria Vezzani, Mina Ryten, Paul M Thompson, Sanjay M Sisodiy. Structural brain abnormalities in the common epilepsies assessed in a worldwide ENIGMA study. Brain : a journal of neurology. vol 141. issue 2. 2019-05-30. PMID:29365066. |
structural brain measures were extracted from mri brain scans across 2149 individuals with epilepsy, divided into four epilepsy subgroups including idiopathic generalized epilepsies (n =367), mesial temporal lobe epilepsies with hippocampal sclerosis (mtle; left, n = 415; right, n = 339), and all other epilepsies in aggregate (n = 1026), and compared to 1727 matched healthy controls. |
2019-05-30 |
2023-08-13 |
Not clear |
| Edward Perez-Reyes, Jung-Ha Le. Ins and outs of T-channel structure function. Pflugers Archiv : European journal of physiology. vol 466. issue 4. 2014-11-24. PMID:24337909. |
studies in cultured hippocampal neurons provided novel insights into how mutations found in idiopathic generalized epilepsy patients increase seizure susceptibility by both altering t-current pacemaker currents and by activating ca-activated transcription factors that regulate dendritic arborization. |
2014-11-24 |
2023-08-12 |
Not clear |
| Yukihiro Yamao, Takeharu Kunieda, Takayuki Kikuchi, Masao Matsuhashi, Nobukatsu Sawamoto, Riki Matsumoto, Tomohisa Okada, Susumu Miyamoto, Akio Iked. [Neuroimaging in epilepsy]. Brain and nerve = Shinkei kenkyu no shinpo. vol 65. issue 5. 2013-08-30. PMID:23667122. |
it is now recommended that magnetic resonance imaging (mri) or computed tomography (ct) be carried out in all patients with at least partial- and hopefully also generalized epilepsy to help identify intracranial lesions, such as hippocampal sclerosis, focal cortical dysplasia, brain tumor, cavernous malformation, and arteriovenous malformation. |
2013-08-30 |
2023-08-12 |
Not clear |
| Pedro Belez. Refractory epilepsy: a clinically oriented review. European neurology. vol 62. issue 2. 2009-09-22. PMID:19521080. |
risk factors for refractoriness include (1) generalized epilepsy with lesions; (2) focal epilepsy with hippocampal sclerosis, cortical dysplasia or hemorrhages; (3) early epilepsy onset; (4) high seizure frequency; (5) absence of response to the first 2 aeds; (6) high frequency of interictal spikes, and (7) multifocal spikes. |
2009-09-22 |
2023-08-12 |
Not clear |
| Yifat Glikmann-Johnston, Michael M Saling, Jian Chen, Kimberlea A Cooper, Richard J Beare, David C Reuten. Structural and functional correlates of unilateral mesial temporal lobe spatial memory impairment. Brain : a journal of neurology. vol 131. issue Pt 11. 2008-12-12. PMID:18790820. |
performance of temporal lobe epilepsy (tle) patients (either unilateral hippocampal sclerosis or anterior temporal lobectomy) on the different spatial memory variables, namely navigation, object location and plan drawing, was significantly worse relative to the comparison groups (either idiopathic generalized epilepsy or controls). |
2008-12-12 |
2023-08-12 |
human |
| Yifat Glikmann-Johnston, Michael M Saling, Jian Chen, Kimberlea A Cooper, Richard J Beare, David C Reuten. Structural and functional correlates of unilateral mesial temporal lobe spatial memory impairment. Brain : a journal of neurology. vol 131. issue Pt 11. 2008-12-12. PMID:18790820. |
fifteen patients with well-characterized unilateral hippocampal sclerosis, 15 patients who had undergone unilateral anterior temporal lobectomy (atl), and a comparison group consisting of 15 patients with idiopathic generalized epilepsy and 25 neurologically healthy participants explored a novel virtual environment. |
2008-12-12 |
2023-08-12 |
human |
| Yifat Glikmann-Johnston, Michael M Saling, Jian Chen, Kimberlea A Cooper, Richard J Beare, David C Reuten. Structural and functional correlates of unilateral mesial temporal lobe spatial memory impairment. Brain : a journal of neurology. vol 131. issue Pt 11. 2008-12-12. PMID:18790820. |
volumetric analyses of both hippocampi were conducted on unilateral hippocampal sclerosis and idiopathic generalized epilepsy patients' t(1)-weighted magnetic resonance imaging scans. |
2008-12-12 |
2023-08-12 |
human |
| Hrvoje Hećimović, Jennifer D Goldstein, Yvette I Sheline, Frank G Gillia. Mechanisms of depression in epilepsy from a clinical perspective. Epilepsy & behavior : E&B. vol 4 Suppl 3. 2004-03-11. PMID:14592637. |
the brain regions commonly involved in various types of epilepsies, such as the hippocampus and amygdala in temporal lobe epilepsy and subcortical nuclei in idiopathic generalized epilepsies, are important components of current models of depression. |
2004-03-11 |
2023-08-12 |
Not clear |
| A Mihály, B Bozók. Immunohistochemical localization of extravasated serum albumin in the hippocampus of human subjects with partial and generalized epilepsies and epileptiform convulsions. Acta neuropathologica. vol 65. issue 1. 1985-02-19. PMID:6516799. |
immunohistochemical localization of extravasated serum albumin in the hippocampus of human subjects with partial and generalized epilepsies and epileptiform convulsions. |
1985-02-19 |
2023-08-12 |
human |
| A M Da. Epilepsy and neuron loss in the hippocampus. Epilepsia. vol 21. issue 6. 1981-02-24. PMID:6777154. |
quantitation of hippocampal neurons was performed in 20 patients with generalized epilepsy. |
1981-02-24 |
2023-08-12 |
Not clear |