All Relations between Epilepsy, Temporal Lobe and hippocampus

Publication Sentence Publish Date Extraction Date Species
Julia Taube, Juri-Alexander Witt, Alexander Grote, Daniel Delev, Jonas Enkirch, Elke Hattingen, Albert J Becker, Christian Erich Elger, Christoph Helmstaedte. Preoperative and postoperative memory in epilepsy patients with 'gliosis only' versus hippocampal sclerosis: a matched case-control study. Journal of neurology, neurosurgery, and psychiatry. 2022-08-25. PMID:36008114. gliosis only (go) and hippocampal sclerosis (hs) are distinct histopathological entities in mesial temporal lobe epilepsy. 2022-08-25 2023-08-14 Not clear
Alexander C Whitebirch, John J LaFrancois, Swati Jain, Paige Leary, Bina Santoro, Steven A Siegelbaum, Helen E Scharfma. Enhanced excitability of the hippocampal CA2 region and its contribution to seizure activity in a mouse model of temporal lobe epilepsy. Neuron. 2022-08-20. PMID:35987207. enhanced excitability of the hippocampal ca2 region and its contribution to seizure activity in a mouse model of temporal lobe epilepsy. 2022-08-20 2023-08-14 mouse
Alexander C Whitebirch, John J LaFrancois, Swati Jain, Paige Leary, Bina Santoro, Steven A Siegelbaum, Helen E Scharfma. Enhanced excitability of the hippocampal CA2 region and its contribution to seizure activity in a mouse model of temporal lobe epilepsy. Neuron. 2022-08-20. PMID:35987207. the hippocampal ca2 region, an area important for social memory, has been suspected to play a role in temporal lobe epilepsy (tle) because of its resistance to degeneration observed in neighboring ca1 and ca3 regions in both humans and rodent models of tle. 2022-08-20 2023-08-14 mouse
Amélie Aussel, Radu Ranta, Olivier Aron, Sophie Colnat-Coulbois, Louise Maillard, Laure Buhr. Cell to network computational model of the epileptic human hippocampus suggests specific roles of network and channel dysfunctions in the ictal and interictal oscillations. Journal of computational neuroscience. 2022-08-15. PMID:35971033. indeed, medial temporal lobe epilepsy is associated with hippocampal abnormalities both at the neuronal (channelopathies, impaired potassium and chloride dynamics) and network level (neuronal and axonal loss, mossy fiber sprouting), with more frequent seizures during wakefulness compared with slow-wave sleep. 2022-08-15 2023-08-14 human
Dalma Tényi, Tamás Tényi, Györgyi Csábi, Sára Jeges, Beáta Bóné, Katalin Lőrincz, Norbert Kovács, József Janszk. Increased prevalence of minor physical anomalies in patients with epilepsy. Scientific reports. vol 12. issue 1. 2022-08-12. PMID:35962048. 235 patients were included, according to the following subgroups: acquired epilepsy (non-genetic, non-developmental etiology) [n = 63], temporal lobe epilepsy with hippocampal sclerosis (tle with hs) [n = 27], epilepsy with cortical dysgenesis etiology [n = 29], cryptogenic epilepsy [n = 69] and idiopathic generalized epilepsy (ige) [n = 47]. 2022-08-12 2023-08-14 human
Maria Zimmermann, Luciano Minuzzi, Arturo Aliaga Aliaga, Marie-Christine Guiot, Jeffery A Hall, Jean-Paul Soucy, Gassan Massarweh, Salah El Mestikawy, Pedro Rosa-Neto, Eliane Kobayash. Reduced Metabotropic Glutamate Receptor Type 5 Availability in the Epileptogenic Hippocampus: An Frontiers in neurology. vol 13. 2022-08-08. PMID:35937057. reduced metabotropic glutamate receptor type 5 availability in the epileptogenic hippocampus: an abnormalities in the expression of metabotropic glutamate receptor type 5 (mglur5) have been observed in the hippocampus of patients with drug-resistant mesial temporal lobe epilepsy (mtle). 2022-08-08 2023-08-14 Not clear
Dinesh Upadhya, Sahithi Attaluri, Yan Liu, Bharathi Hattiangady, Olagide W Castro, Bing Shuai, Yi Dong, Su-Chun Zhang, Ashok K Shett. Grafted hPSC-derived GABA-ergic interneurons regulate seizures and specific cognitive function in temporal lobe epilepsy. NPJ Regenerative medicine. vol 7. issue 1. 2022-08-01. PMID:35915118. interneuron loss/dysfunction contributes to spontaneous recurrent seizures (srs) in chronic temporal lobe epilepsy (tle), and interneuron grafting into the epileptic hippocampus reduces srs and improves cognitive function. 2022-08-01 2023-08-14 human
b' Barbara Sita\\xc5\\xa1, Mihaela Bobi\\xc4\\x87-Rasonja, Goran Mrak, Sara Trnski, Magdalena Krbot Skori\\xc4\\x87, Darko Ore\\xc5\\xa1kovi\\xc4\\x87, Vinka Knezovi\\xc4\\x87, \\xc5\\xbdeljka Petelin Gad\\xc5\\xbee, Zdravko Petanjek, Goran \\xc5\\xa0imi\\xc4\\x87, Danijela Kolenc, Nata\\xc5\\xa1a Jovanov Milo\\xc5\\xa1evi\\xc4\\x8. Reorganization of the Brain Extracellular Matrix in Hippocampal Sclerosis. International journal of molecular sciences. vol 23. issue 15. 2022-07-28. PMID:35897768.' in patients with drug-resistant mesial temporal lobe epilepsy (mtle), hippocampal sclerosis type 1 (hs1) is the most common histopathological finding. 2022-07-28 2023-08-14 Not clear
b' B\\xc3\\xa1rbara Guerra Leal, Aurora Barros-Barbosa, F\\xc3\\xa1tima Ferreirinha, Jo\\xc3\\xa3o Chaves, Rui Rangel, Agostinho Santos, Cl\\xc3\\xa1udia Carvalho, Ricardo Martins-Ferreira, Raquel Sam\\xc3\\xb5es, Joel Freitas, Jo\\xc3\\xa3o Lopes, Jo\\xc3\\xa3o Ramalheira, Maria Gra\\xc3\\xa7a Lobo, Ant\\xc3\\xb3nio Martins da Silva, Paulo P Costa, Paulo Correia-de-S\\xc3\\xa. Mesial Temporal Lobe Epilepsy (MTLE) Drug-Refractoriness Is Associated With P2X7 Receptors Overexpression in the Human Hippocampus and Temporal Neocortex and May Be Predicted by Low Circulating Levels of miR-22. Frontiers in cellular neuroscience. vol 16. 2022-07-25. PMID:35875355.' mesial temporal lobe epilepsy (mtle) drug-refractoriness is associated with p2x7 receptors overexpression in the human hippocampus and temporal neocortex and may be predicted by low circulating levels of mir-22. 2022-07-25 2023-08-14 human
Alexey A Kulikov, Alexandra A Naumova, Nadezhda A Dorofeeva, Andrey P Ivlev, Margarita V Glazova, Elena V Chernigovskay. Dynamics of neurodegeneration in the hippocampus of Krushinsky-Molodkina rats correlates with the progression of limbic seizures. Epilepsy & behavior : E&B. vol 134. 2022-07-18. PMID:35849865. temporal lobe epilepsy is accompanied with neurodegeneration in the hippocampus, but how the cells die is not fully understood. 2022-07-18 2023-08-14 rat
Dong An, Xiuting Qi, Kunpeng Li, Weixing Xu, Yue Wang, Xi Chen, Sha Sha, Chunfeng Wu, Yimei Du, Lei Che. Blockage of TRPV4 Downregulates the Nuclear Factor-Kappa B Signaling Pathway to Inhibit Inflammatory Responses and Neuronal Death in Mice with Pilocarpine-Induced Status Epilepticus. Cellular and molecular neurobiology. 2022-07-15. PMID:35840809. the blockage of transient receptor potential vanilloid 4 (trpv4) inhibits inflammation and reduces hippocampal neuronal injury in a pilocarpine-induced mouse model of temporal lobe epilepsy. 2022-07-15 2023-08-14 mouse
Raluca Ica, Kristina Mlinac-Jerkovic, Katarina Ilic, Tomislav Sajko, Cristian V A Munteanu, Alina D Zamfir, Svjetlana Kalanj-Bogna. Gangliosidome of a Human Hippocampus in Temporal Lobe Epilepsy Resolved by High-Resolution Tandem Mass Spectrometry. Molecules (Basel, Switzerland). vol 27. issue 13. 2022-07-09. PMID:35807302. gangliosidome of a human hippocampus in temporal lobe epilepsy resolved by high-resolution tandem mass spectrometry. 2022-07-09 2023-08-14 human
Raluca Ica, Kristina Mlinac-Jerkovic, Katarina Ilic, Tomislav Sajko, Cristian V A Munteanu, Alina D Zamfir, Svjetlana Kalanj-Bogna. Gangliosidome of a Human Hippocampus in Temporal Lobe Epilepsy Resolved by High-Resolution Tandem Mass Spectrometry. Molecules (Basel, Switzerland). vol 27. issue 13. 2022-07-09. PMID:35807302. in this study, we developed a high-resolution tandem mass spectrometry (hr ms) approach to assess presumed changes in gangliosidome of a human hippocampus affected by temporal lobe epilepsy (tle) in comparison with a normal hippocampus. 2022-07-09 2023-08-14 human
Jacint Sala-Padro, Ariadna Gifreu-Fraixino, Júlia Miró, Antoni Rodriguez-Fornells, Immaculada Rico, Gerard Plans, Mila Santurino, Mercè Falip, Estela Càmar. Verbal Learning and Longitudinal Hippocampal Network Connectivity in Temporal Lobe Epilepsy Surgery. Frontiers in neurology. vol 13. 2022-07-08. PMID:35800085. verbal learning and longitudinal hippocampal network connectivity in temporal lobe epilepsy surgery. 2022-07-08 2023-08-14 Not clear
Michaela Shishmanova-Doseva, Dimitrinka Atanasova, Lyubka Ioanidu, Yordanka Uzunova, Milena Atanasova, Lyudmil Peychev, Jana Tchekalarov. The anticonvulsant effect of chronic treatment with topiramate after pilocarpine-induced status epilepticus is accompanied by a suppression of comorbid behavioral impairments and robust neuroprotection in limbic regions in rats. Epilepsy & behavior : E&B. vol 134. 2022-07-06. PMID:35792414. the present study aimed to evaluate the effects of the antiseizure medication topiramate (tpm) on spontaneous motor seizures, the pathogenesis of comorbid mood and cognitive impairments, hippocampal neuronal loss, and oxidative stress and inflammation in a rat model of temporal lobe epilepsy (tle). 2022-07-06 2023-08-14 rat
Zhi-Bin Wang, Jian Qu, Zhuan-Yi Yang, Ding-Yang Liu, Shi-Long Jiang, Ying Zhang, Zhi-Quan Yang, Xiao-Yuan Mao, Zhao-Qian Li. Integrated Analysis of Expression Profile and Potential Pathogenic Mechanism of Temporal Lobe Epilepsy With Hippocampal Sclerosis. Frontiers in neuroscience. vol 16. 2022-07-05. PMID:35784838. integrated analysis of expression profile and potential pathogenic mechanism of temporal lobe epilepsy with hippocampal sclerosis. 2022-07-05 2023-08-14 Not clear
Zhi-Bin Wang, Jian Qu, Zhuan-Yi Yang, Ding-Yang Liu, Shi-Long Jiang, Ying Zhang, Zhi-Quan Yang, Xiao-Yuan Mao, Zhao-Qian Li. Integrated Analysis of Expression Profile and Potential Pathogenic Mechanism of Temporal Lobe Epilepsy With Hippocampal Sclerosis. Frontiers in neuroscience. vol 16. 2022-07-05. PMID:35784838. to investigate the potential pathogenic mechanism of temporal lobe epilepsy with hippocampal sclerosis (tle+hs) by analyzing the expression profiles of microrna/ mrna/ lncrna/ dna methylation in brain tissues. 2022-07-05 2023-08-14 Not clear
Sara Cavaco, Bruno Moreira, Daniel Dias, Alexandra Gonçalves, Claudia Pinto, Eduarda Almeida, Filomena Gomes, Inês Moreira, João Chaves, João Lopes, João Ramalheira, Joel Freitas, Raquel Samões, Rui Rangel, António Martins da Silv. Auditory verbal learning test can lateralize hippocampal sclerosis. Applied neuropsychology. Adult. 2022-06-27. PMID:35754382. the ability of the auditory verbal learning test (avlt) to lateralize hippocampal sclerosis (hs) in mesial temporal lobe epilepsy (mtle) was explored in a sample of 50 patients with mtle-hs (23 right and 27 left). 2022-06-27 2023-08-14 Not clear
Rosita Shishegar, Ziba Gandomkar, Alireza Fallahi, Mohammad-Reza Nazem-Zadeh, Hamid Soltanian-Zade. Global and local shape features of the hippocampus based on Laplace-Beltrami eigenvalues and eigenfunctions: a potential application in the lateralization of temporal lobe epilepsy. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. 2022-06-22. PMID:35732961. global and local shape features of the hippocampus based on laplace-beltrami eigenvalues and eigenfunctions: a potential application in the lateralization of temporal lobe epilepsy. 2022-06-22 2023-08-14 human
Vega-García Angélica, Guevara-Guzmán Rosalinda, García-Gómez Omar, Feria-Romero Iris, Fernández-Valverde Francisca, Alonso-Vanegas Mario, Orozco-Suárez Sandr. Aberrant connection formation and glia involvement in the progression of pharmacoresistant mesial temporal lobe epilepsy. Current pharmaceutical design. 2022-06-17. PMID:35713147. epilepsy is the most common chronic neurological disease, affecting approximately 65 million people worldwide, with mesial temporal lobe epilepsy (mtle) being the most common type, characterized by the presence of focal seizures that begin in the hippocampus and subsequently generalize to structures such as the cerebral cortex. 2022-06-17 2023-08-14 Not clear