| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Dinesh Upadhya, Sahithi Attaluri, Yan Liu, Bharathi Hattiangady, Olagide W Castro, Bing Shuai, Yi Dong, Su-Chun Zhang, Ashok K Shett. Grafted hPSC-derived GABA-ergic interneurons regulate seizures and specific cognitive function in temporal lobe epilepsy. NPJ Regenerative medicine. vol 7. issue 1. 2022-08-01. PMID:35915118. |
interneuron loss/dysfunction contributes to spontaneous recurrent seizures (srs) in chronic temporal lobe epilepsy (tle), and interneuron grafting into the epileptic hippocampus reduces srs and improves cognitive function. |
2022-08-01 |
2023-08-14 |
human |
| b' Barbara Sita\\xc5\\xa1, Mihaela Bobi\\xc4\\x87-Rasonja, Goran Mrak, Sara Trnski, Magdalena Krbot Skori\\xc4\\x87, Darko Ore\\xc5\\xa1kovi\\xc4\\x87, Vinka Knezovi\\xc4\\x87, \\xc5\\xbdeljka Petelin Gad\\xc5\\xbee, Zdravko Petanjek, Goran \\xc5\\xa0imi\\xc4\\x87, Danijela Kolenc, Nata\\xc5\\xa1a Jovanov Milo\\xc5\\xa1evi\\xc4\\x8. Reorganization of the Brain Extracellular Matrix in Hippocampal Sclerosis. International journal of molecular sciences. vol 23. issue 15. 2022-07-28. PMID:35897768.' |
in patients with drug-resistant mesial temporal lobe epilepsy (mtle), hippocampal sclerosis type 1 (hs1) is the most common histopathological finding. |
2022-07-28 |
2023-08-14 |
Not clear |
| b' B\\xc3\\xa1rbara Guerra Leal, Aurora Barros-Barbosa, F\\xc3\\xa1tima Ferreirinha, Jo\\xc3\\xa3o Chaves, Rui Rangel, Agostinho Santos, Cl\\xc3\\xa1udia Carvalho, Ricardo Martins-Ferreira, Raquel Sam\\xc3\\xb5es, Joel Freitas, Jo\\xc3\\xa3o Lopes, Jo\\xc3\\xa3o Ramalheira, Maria Gra\\xc3\\xa7a Lobo, Ant\\xc3\\xb3nio Martins da Silva, Paulo P Costa, Paulo Correia-de-S\\xc3\\xa. Mesial Temporal Lobe Epilepsy (MTLE) Drug-Refractoriness Is Associated With P2X7 Receptors Overexpression in the Human Hippocampus and Temporal Neocortex and May Be Predicted by Low Circulating Levels of miR-22. Frontiers in cellular neuroscience. vol 16. 2022-07-25. PMID:35875355.' |
mesial temporal lobe epilepsy (mtle) drug-refractoriness is associated with p2x7 receptors overexpression in the human hippocampus and temporal neocortex and may be predicted by low circulating levels of mir-22. |
2022-07-25 |
2023-08-14 |
human |
| Alexey A Kulikov, Alexandra A Naumova, Nadezhda A Dorofeeva, Andrey P Ivlev, Margarita V Glazova, Elena V Chernigovskay. Dynamics of neurodegeneration in the hippocampus of Krushinsky-Molodkina rats correlates with the progression of limbic seizures. Epilepsy & behavior : E&B. vol 134. 2022-07-18. PMID:35849865. |
temporal lobe epilepsy is accompanied with neurodegeneration in the hippocampus, but how the cells die is not fully understood. |
2022-07-18 |
2023-08-14 |
rat |
| Dong An, Xiuting Qi, Kunpeng Li, Weixing Xu, Yue Wang, Xi Chen, Sha Sha, Chunfeng Wu, Yimei Du, Lei Che. Blockage of TRPV4 Downregulates the Nuclear Factor-Kappa B Signaling Pathway to Inhibit Inflammatory Responses and Neuronal Death in Mice with Pilocarpine-Induced Status Epilepticus. Cellular and molecular neurobiology. 2022-07-15. PMID:35840809. |
the blockage of transient receptor potential vanilloid 4 (trpv4) inhibits inflammation and reduces hippocampal neuronal injury in a pilocarpine-induced mouse model of temporal lobe epilepsy. |
2022-07-15 |
2023-08-14 |
mouse |
| Raluca Ica, Kristina Mlinac-Jerkovic, Katarina Ilic, Tomislav Sajko, Cristian V A Munteanu, Alina D Zamfir, Svjetlana Kalanj-Bogna. Gangliosidome of a Human Hippocampus in Temporal Lobe Epilepsy Resolved by High-Resolution Tandem Mass Spectrometry. Molecules (Basel, Switzerland). vol 27. issue 13. 2022-07-09. PMID:35807302. |
gangliosidome of a human hippocampus in temporal lobe epilepsy resolved by high-resolution tandem mass spectrometry. |
2022-07-09 |
2023-08-14 |
human |
| Raluca Ica, Kristina Mlinac-Jerkovic, Katarina Ilic, Tomislav Sajko, Cristian V A Munteanu, Alina D Zamfir, Svjetlana Kalanj-Bogna. Gangliosidome of a Human Hippocampus in Temporal Lobe Epilepsy Resolved by High-Resolution Tandem Mass Spectrometry. Molecules (Basel, Switzerland). vol 27. issue 13. 2022-07-09. PMID:35807302. |
in this study, we developed a high-resolution tandem mass spectrometry (hr ms) approach to assess presumed changes in gangliosidome of a human hippocampus affected by temporal lobe epilepsy (tle) in comparison with a normal hippocampus. |
2022-07-09 |
2023-08-14 |
human |
| Jacint Sala-Padro, Ariadna Gifreu-Fraixino, Júlia Miró, Antoni Rodriguez-Fornells, Immaculada Rico, Gerard Plans, Mila Santurino, Mercè Falip, Estela Càmar. Verbal Learning and Longitudinal Hippocampal Network Connectivity in Temporal Lobe Epilepsy Surgery. Frontiers in neurology. vol 13. 2022-07-08. PMID:35800085. |
verbal learning and longitudinal hippocampal network connectivity in temporal lobe epilepsy surgery. |
2022-07-08 |
2023-08-14 |
Not clear |
| Michaela Shishmanova-Doseva, Dimitrinka Atanasova, Lyubka Ioanidu, Yordanka Uzunova, Milena Atanasova, Lyudmil Peychev, Jana Tchekalarov. The anticonvulsant effect of chronic treatment with topiramate after pilocarpine-induced status epilepticus is accompanied by a suppression of comorbid behavioral impairments and robust neuroprotection in limbic regions in rats. Epilepsy & behavior : E&B. vol 134. 2022-07-06. PMID:35792414. |
the present study aimed to evaluate the effects of the antiseizure medication topiramate (tpm) on spontaneous motor seizures, the pathogenesis of comorbid mood and cognitive impairments, hippocampal neuronal loss, and oxidative stress and inflammation in a rat model of temporal lobe epilepsy (tle). |
2022-07-06 |
2023-08-14 |
rat |
| Zhi-Bin Wang, Jian Qu, Zhuan-Yi Yang, Ding-Yang Liu, Shi-Long Jiang, Ying Zhang, Zhi-Quan Yang, Xiao-Yuan Mao, Zhao-Qian Li. Integrated Analysis of Expression Profile and Potential Pathogenic Mechanism of Temporal Lobe Epilepsy With Hippocampal Sclerosis. Frontiers in neuroscience. vol 16. 2022-07-05. PMID:35784838. |
integrated analysis of expression profile and potential pathogenic mechanism of temporal lobe epilepsy with hippocampal sclerosis. |
2022-07-05 |
2023-08-14 |
Not clear |
| Zhi-Bin Wang, Jian Qu, Zhuan-Yi Yang, Ding-Yang Liu, Shi-Long Jiang, Ying Zhang, Zhi-Quan Yang, Xiao-Yuan Mao, Zhao-Qian Li. Integrated Analysis of Expression Profile and Potential Pathogenic Mechanism of Temporal Lobe Epilepsy With Hippocampal Sclerosis. Frontiers in neuroscience. vol 16. 2022-07-05. PMID:35784838. |
to investigate the potential pathogenic mechanism of temporal lobe epilepsy with hippocampal sclerosis (tle+hs) by analyzing the expression profiles of microrna/ mrna/ lncrna/ dna methylation in brain tissues. |
2022-07-05 |
2023-08-14 |
Not clear |
| Sara Cavaco, Bruno Moreira, Daniel Dias, Alexandra Gonçalves, Claudia Pinto, Eduarda Almeida, Filomena Gomes, Inês Moreira, João Chaves, João Lopes, João Ramalheira, Joel Freitas, Raquel Samões, Rui Rangel, António Martins da Silv. Auditory verbal learning test can lateralize hippocampal sclerosis. Applied neuropsychology. Adult. 2022-06-27. PMID:35754382. |
the ability of the auditory verbal learning test (avlt) to lateralize hippocampal sclerosis (hs) in mesial temporal lobe epilepsy (mtle) was explored in a sample of 50 patients with mtle-hs (23 right and 27 left). |
2022-06-27 |
2023-08-14 |
Not clear |
| Rosita Shishegar, Ziba Gandomkar, Alireza Fallahi, Mohammad-Reza Nazem-Zadeh, Hamid Soltanian-Zade. Global and local shape features of the hippocampus based on Laplace-Beltrami eigenvalues and eigenfunctions: a potential application in the lateralization of temporal lobe epilepsy. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. 2022-06-22. PMID:35732961. |
global and local shape features of the hippocampus based on laplace-beltrami eigenvalues and eigenfunctions: a potential application in the lateralization of temporal lobe epilepsy. |
2022-06-22 |
2023-08-14 |
human |
| Vega-García Angélica, Guevara-Guzmán Rosalinda, García-Gómez Omar, Feria-Romero Iris, Fernández-Valverde Francisca, Alonso-Vanegas Mario, Orozco-Suárez Sandr. Aberrant connection formation and glia involvement in the progression of pharmacoresistant mesial temporal lobe epilepsy. Current pharmaceutical design. 2022-06-17. PMID:35713147. |
epilepsy is the most common chronic neurological disease, affecting approximately 65 million people worldwide, with mesial temporal lobe epilepsy (mtle) being the most common type, characterized by the presence of focal seizures that begin in the hippocampus and subsequently generalize to structures such as the cerebral cortex. |
2022-06-17 |
2023-08-14 |
Not clear |
| Hakan Sahin, Oguz Yucel, Serkan Emik, Gozde Erkanli Sentur. Protective Effects of Intranasally Administrated Oxytocin-Loaded Nanoparticles on Pentylenetetrazole-Kindling Epilepsy in Terms of Seizure Severity, Memory, Neurogenesis, and Neuronal Damage. ACS chemical neuroscience. 2022-06-17. PMID:35713692. |
pentylenetetrazole (ptz)-induced kindling is an animal model for studying human temporal lobe epilepsy (tle), which is characterized by alterations of hippocampal neurons and memory. |
2022-06-17 |
2023-08-14 |
human |
| Yuanyuan Yao, Yang Hu, Jiurong Yang, Canyu Zhang, Yuqi He, Honggang Qi, Yu Zeng, Aifeng Zhang, Xiufang Liu, Xinjian Zh. Inhibition of neuronal nitric oxide synthase protects against hippocampal neuronal injuries by increasing neuropeptide Y expression in temporal lobe epilepsy mice. Free radical biology & medicine. 2022-06-17. PMID:35714846. |
inhibition of neuronal nitric oxide synthase protects against hippocampal neuronal injuries by increasing neuropeptide y expression in temporal lobe epilepsy mice. |
2022-06-17 |
2023-08-14 |
mouse |
| Yuanyuan Yao, Yang Hu, Jiurong Yang, Canyu Zhang, Yuqi He, Honggang Qi, Yu Zeng, Aifeng Zhang, Xiufang Liu, Xinjian Zh. Inhibition of neuronal nitric oxide synthase protects against hippocampal neuronal injuries by increasing neuropeptide Y expression in temporal lobe epilepsy mice. Free radical biology & medicine. 2022-06-17. PMID:35714846. |
our results showed that pilocarpine-induced temporal lobe epilepsy (tle) mice exhibited an increased level of nnos expression and a decreased level of npy expression along with hippocampal neuronal injuries and cognition deficit. |
2022-06-17 |
2023-08-14 |
mouse |
| Daniela Gattás, Fermino Sanches Lizarte Neto, Priscila Freitas-Lima, Ricardo Bonfim-Silva, Serguey Malaquias de Almeida, Mucio Luiz de Assis Cirino, Daniel Guimarães Tiezzi, Luis Fernando Tirapelli, Tonicarlo Rodrigues Velasco, Americo Ceiki Sakamoto, Caio Marconato Matias, Carlos Gilberto Carlotti Jr, Daniela Pretti da Cunha Tirapell. MicroRNAs miR-629-3p, miR-1202 and miR-1225-5p as potential diagnostic and surgery outcome biomarkers for mesial temporal lobe epilepsy with hippocampal sclerosis. Neuro-Chirurgie. 2022-06-14. PMID:35700789. |
micrornas mir-629-3p, mir-1202 and mir-1225-5p as potential diagnostic and surgery outcome biomarkers for mesial temporal lobe epilepsy with hippocampal sclerosis. |
2022-06-14 |
2023-08-14 |
Not clear |
| Daniela Gattás, Fermino Sanches Lizarte Neto, Priscila Freitas-Lima, Ricardo Bonfim-Silva, Serguey Malaquias de Almeida, Mucio Luiz de Assis Cirino, Daniel Guimarães Tiezzi, Luis Fernando Tirapelli, Tonicarlo Rodrigues Velasco, Americo Ceiki Sakamoto, Caio Marconato Matias, Carlos Gilberto Carlotti Jr, Daniela Pretti da Cunha Tirapell. MicroRNAs miR-629-3p, miR-1202 and miR-1225-5p as potential diagnostic and surgery outcome biomarkers for mesial temporal lobe epilepsy with hippocampal sclerosis. Neuro-Chirurgie. 2022-06-14. PMID:35700789. |
mesial temporal lobe epilepsy (mtle) is a symptomatic epilepsy syndrome clinically characterized by high prevalence, pharmacoresistance, good surgical prognosis and hippocampal sclerosis (hs); however, no singular criteria can be considered sufficient for the mtle-hs diagnosis. |
2022-06-14 |
2023-08-14 |
Not clear |
| Samantha Tamrakar, Yasushi Iimura, Hiroharu Suzuki, Takumi Mitsuhashi, Tetsuya Ueda, Kazuki Nishioka, Kostadin Karagiozov, Madoka Nakajima, Yao Miao, Toshihisa Tanaka, Hidenori Sugan. Higher phase-amplitude coupling between ripple and slow oscillations indicates the distribution of epileptogenicity in temporal lobe epilepsy with hippocampal sclerosis. Seizure. vol 100. 2022-06-10. PMID:35687962. |
higher phase-amplitude coupling between ripple and slow oscillations indicates the distribution of epileptogenicity in temporal lobe epilepsy with hippocampal sclerosis. |
2022-06-10 |
2023-08-14 |
Not clear |