| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Eugene Chun, Argyle V Bumanglag, Sara N Burke, Robert S Slovite. Targeted hippocampal GABA neuron ablation by Stable Substance P-saporin causes hippocampal sclerosis and chronic epilepsy in rats. Epilepsia. vol 60. issue 5. 2020-04-27. PMID:30963545. |
in this study, hippocampal gaba neurons were targeted for selective elimination to determine whether a focal hippocampal gabaergic defect in an otherwise normal brain can initiate cryptogenic temporal lobe epilepsy with hippocampal sclerosis. |
2020-04-27 |
2023-08-13 |
rat |
| Eugene Chun, Argyle V Bumanglag, Sara N Burke, Robert S Slovite. Targeted hippocampal GABA neuron ablation by Stable Substance P-saporin causes hippocampal sclerosis and chronic epilepsy in rats. Epilepsia. vol 60. issue 5. 2020-04-27. PMID:30963545. |
these data suggest that hippocampal gabaergic dysfunction is epileptogenic and can produce the defining features of cryptogenic temporal lobe epilepsy. |
2020-04-27 |
2023-08-13 |
rat |
| Jana Desloovere, Paul Boon, Lars E Larsen, Caroline Merckx, Marie-Gabrielle Goossens, Chris Van den Haute, Veerle Baekelandt, Dimitri De Bundel, Evelien Carrette, Jean Delbeke, Alfred Meurs, Kristl Vonck, Wytse Wadman, Robrecht Raed. Long-term chemogenetic suppression of spontaneous seizures in a mouse model for temporal lobe epilepsy. Epilepsia. vol 60. issue 11. 2020-04-15. PMID:31608439. |
in this study, we evaluated the effect of chemogenetic suppression of excitatory pyramidal and granule cell neurons of the sclerotic hippocampus in the intrahippocampal mouse model (ihka) for temporal lobe epilepsy. |
2020-04-15 |
2023-08-13 |
mouse |
| Wendy Klement, Marine Blaquiere, Emma Zub, Frederic deBock, Fabien Boux, Emmanuel Barbier, Etienne Audinat, Mireille Lerner-Natoli, Nicola March. A pericyte-glia scarring develops at the leaky capillaries in the hippocampus during seizure activity. Epilepsia. vol 60. issue 7. 2020-04-14. PMID:31135065. |
here, we tested the hypothesis that a pericyte-glia scar forms around the outer wall of hippocampal capillaries in a model of temporal lobe epilepsy associated with hippocampal sclerosis. |
2020-04-14 |
2023-08-13 |
Not clear |
| Elisabeth Roggenhofer, Emiliano Santarnecchi, Sandrine Muller, Ferath Kherif, Roland Wiest, Margitta Seeck, Bogdan Dragansk. Trajectories of brain remodeling in temporal lobe epilepsy. Journal of neurology. vol 266. issue 12. 2020-04-14. PMID:31549200. |
we acquired mris from a large cohort of mesial temporal lobe epilepsy patients with or without hippocampus sclerosis on radiological examination. |
2020-04-14 |
2023-08-13 |
Not clear |
| Elisabeth Roggenhofer, Emiliano Santarnecchi, Sandrine Muller, Ferath Kherif, Roland Wiest, Margitta Seeck, Bogdan Dragansk. Trajectories of brain remodeling in temporal lobe epilepsy. Journal of neurology. vol 266. issue 12. 2020-04-14. PMID:31549200. |
the main effect of disease was associated with continuous hippocampus volume loss ipsilateral to the seizure onset zone in both temporal lobe epilepsy cohorts. |
2020-04-14 |
2023-08-13 |
Not clear |
| Preya Shah, Danielle S Bassett, Laura E M Wisse, John A Detre, Joel M Stein, Paul A Yushkevich, Russell T Shinohara, Mark A Elliott, Sandhitsu R Das, Kathryn A Davi. Structural and functional asymmetry of medial temporal subregions in unilateral temporal lobe epilepsy: A 7T MRI study. Human brain mapping. vol 40. issue 8. 2020-04-13. PMID:30666753. |
mesial temporal lobe epilepsy (tle) is a common neurological disorder affecting the hippocampus and surrounding medial temporal lobe (mtl). |
2020-04-13 |
2023-08-13 |
human |
| Tátila Martins Lopes, Brunno Machado de Campos, Tamires Araújo Zanão, Marcio L F Balthazar, Clarissa Lin Yasuda, Fernando Cende. Hippocampal atrophy disrupts the language network but not hemispheric language lateralization. Epilepsia. vol 60. issue 4. 2020-04-13. PMID:30875437. |
it is still unclear how temporal lobe epilepsy (tle) with and without hippocampal atrophy (ha) affects cortical language distribution. |
2020-04-13 |
2023-08-13 |
Not clear |
| Luana Grupioni Lourenço Antônio, Priscila Freitas-Lima, Gabriela Pereira-da-Silva, João Alberto Assirati, Caio Marconato Matias, Mucio Luiz Assis Cirino, Luis Fernando Tirapelli, Tonicarlo Rodrigues Velasco, Americo Ceiki Sakamoto, Carlos Gilberto Carlotti, Daniela Pretti da Cunha Tirapell. Expression of MicroRNAs miR-145, miR-181c, miR-199a and miR-1183 in the Blood and Hippocampus of Patients with Mesial Temporal Lobe Epilepsy. Journal of molecular neuroscience : MN. vol 69. issue 4. 2020-04-13. PMID:31368064. |
expression of micrornas mir-145, mir-181c, mir-199a and mir-1183 in the blood and hippocampus of patients with mesial temporal lobe epilepsy. |
2020-04-13 |
2023-08-13 |
Not clear |
| Luana Grupioni Lourenço Antônio, Priscila Freitas-Lima, Gabriela Pereira-da-Silva, João Alberto Assirati, Caio Marconato Matias, Mucio Luiz Assis Cirino, Luis Fernando Tirapelli, Tonicarlo Rodrigues Velasco, Americo Ceiki Sakamoto, Carlos Gilberto Carlotti, Daniela Pretti da Cunha Tirapell. Expression of MicroRNAs miR-145, miR-181c, miR-199a and miR-1183 in the Blood and Hippocampus of Patients with Mesial Temporal Lobe Epilepsy. Journal of molecular neuroscience : MN. vol 69. issue 4. 2020-04-13. PMID:31368064. |
the aim of this study was to analyze the expression profiles of the micrornas (mirnas) mir-145, mir-181c, mir-199a and mir-1183 in the hippocampus and blood of patients with mesial temporal lobe epilepsy with hippocampal sclerosis (mtle-hs) and to investigate whether these can be used as diagnosis and prognosis biomarkers for epilepsy. |
2020-04-13 |
2023-08-13 |
Not clear |
| Susanne Tulke, Carola A Haas, Ute Häussle. Expression of brain-derived neurotrophic factor and structural plasticity in the dentate gyrus and CA2 region correlate with epileptiform activity. Epilepsia. vol 60. issue 6. 2020-04-10. PMID:31121074. |
hippocampal sclerosis is a hallmark of mesial temporal lobe epilepsy (mtle), comprising gliosis and neuronal loss in the hippocampus. |
2020-04-10 |
2023-08-13 |
Not clear |
| William A Schraegle, Nancy L Nussbaum, Jeffrey B Titu. Executive Dysfunction and Depression in Pediatric Temporal Lobe Epilepsy: The Contribution of Hippocampal Sclerosis and Psychosocial Factors. Journal of the International Neuropsychological Society : JINS. vol 24. issue 6. 2020-04-09. PMID:29573759. |
executive dysfunction and depression in pediatric temporal lobe epilepsy: the contribution of hippocampal sclerosis and psychosocial factors. |
2020-04-09 |
2023-08-13 |
Not clear |
| Siti Nurbaya Yaakub, Gareth J Barker, Sarah J Carr, Eugenio Abela, Michalis Koutroumanidis, Robert D C Elwes, Mark P Richardso. Abnormal temporal lobe morphology in asymptomatic relatives of patients with hippocampal sclerosis: A replication study. Epilepsia. vol 60. issue 1. 2020-04-09. PMID:30324623. |
we investigated gray and white matter morphology in patients with mesial temporal lobe epilepsy with hippocampal sclerosis (mtle+hs) and first-degree asymptomatic relatives of patients with mtle+hs. |
2020-04-09 |
2023-08-13 |
human |
| Xin Tong, Dongmei An, Fenglai Xiao, Du Lei, Running Niu, Wei Li, Jiechuan Ren, Wenyu Liu, Yingying Tang, Le Zhang, Baiwan Zhou, Qiyong Gong, Dong Zho. Real-time effects of interictal spikes on hippocampus and amygdala functional connectivity in unilateral temporal lobe epilepsy: An EEG-fMRI study. Epilepsia. vol 60. issue 2. 2020-04-08. PMID:30653664. |
real-time effects of interictal spikes on hippocampus and amygdala functional connectivity in unilateral temporal lobe epilepsy: an eeg-fmri study. |
2020-04-08 |
2023-08-13 |
Not clear |
| Xin Tong, Dongmei An, Fenglai Xiao, Du Lei, Running Niu, Wei Li, Jiechuan Ren, Wenyu Liu, Yingying Tang, Le Zhang, Baiwan Zhou, Qiyong Gong, Dong Zho. Real-time effects of interictal spikes on hippocampus and amygdala functional connectivity in unilateral temporal lobe epilepsy: An EEG-fMRI study. Epilepsia. vol 60. issue 2. 2020-04-08. PMID:30653664. |
to explore the real-time effects of interictal epileptiform discharges (ieds) on hippocampus and amygdala functional connectivity (fc) in unilateral temporal lobe epilepsy (tle). |
2020-04-08 |
2023-08-13 |
Not clear |
| William D Hendricks, Gary L Westbrook, Eric Schnel. Early detonation by sprouted mossy fibers enables aberrant dentate network activity. Proceedings of the National Academy of Sciences of the United States of America. vol 116. issue 22. 2020-04-06. PMID:31085654. |
in temporal lobe epilepsy, sprouting of hippocampal mossy fiber axons onto dentate granule cell dendrites creates a recurrent excitatory network. |
2020-04-06 |
2023-08-13 |
Not clear |
| Fernando Cende. Evidence for a genetic effect in altered cortical surface area but not in cortical thinning in siblings of patients with mesial temporal lobe epilepsy: Commentary on: "Abnormal temporal lobe morphology in asymptomatic relatives of patients with hippocampal sclerosis: A replication study". Epilepsia. vol 60. issue 1. 2020-04-02. PMID:30592033. |
evidence for a genetic effect in altered cortical surface area but not in cortical thinning in siblings of patients with mesial temporal lobe epilepsy: commentary on: "abnormal temporal lobe morphology in asymptomatic relatives of patients with hippocampal sclerosis: a replication study". |
2020-04-02 |
2023-08-13 |
Not clear |
| Benoit Girard, Pola Tuduri, Maria Paula Moreno, Sophie Sakkaki, Cedric Barboux, Tristan Bouschet, Annie Varrault, Jihane Vitre, Isabelle McCort-Tranchepain, Julien Dairou, Francine Acher, Laurent Fagni, Nicola Marchi, Julie Perroy, Federica Bertas. The mGlu7 receptor provides protective effects against epileptogenesis and epileptic seizures. Neurobiology of disease. vol 129. 2020-03-24. PMID:31051234. |
in the intra-hippocampal injection of kainic acid mouse model that mimics the human mesial temporal lobe epilepsy, we found that lsp2-9166 reduces seizure frequency and hippocampal sclerosis. |
2020-03-24 |
2023-08-13 |
mouse |
| Pavel Řehulka, Jan Cimbálník, Martin Pail, Jan Chrastina, Markéta Hermanová, Milan Brázdi. Hippocampal high frequency oscillations in unilateral and bilateral mesial temporal lobe epilepsy. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. vol 130. issue 7. 2020-03-18. PMID:31100580. |
hippocampal high frequency oscillations in unilateral and bilateral mesial temporal lobe epilepsy. |
2020-03-18 |
2023-08-13 |
Not clear |
| Priscila S R Simões, Alexia O Zanelatto, Mirian C Assis, Pedro Paulo V Varella, Elza Marcia Yacubian, Henrique Carrete, Ricardo Centeno, Mariana S Araujo, Esper A Cavalheiro, Ivarne Luis S Tersariol, Guacyara Motta, Maria da Graça Naffah-Mazzacoratt. Plasma kallikrein-kinin system contributes to peripheral inflammation in temporal lobe epilepsy. Journal of neurochemistry. vol 150. issue 3. 2020-03-18. PMID:31206169. |
temporal lobe epilepsy (tle) is a chronic disease, characterized by severe and refractory seizures, triggered in the hippocampus and/or amygdala, disrupting the blood-brain barrier. |
2020-03-18 |
2023-08-13 |
human |