| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Davide Caron, Stefano Buccelli, Angel Canal-Alonso, Javad A Farsani, Giacomo Pruzzo, Bernabe Linares-Barranco, Juan Manuel Corchado, Michela Chiappalone, Gabriella Panucci. Biohybrid restoration of the hippocampal loop re-establishes the non-seizing state in an in vitro model of limbic seizures. Journal of neural engineering. 2023-07-20. PMID:37473748. |
the compromise of the hippocampal loop is a hallmark of mesial temporal lobe epilepsy (mtle), the most frequent epileptic syndrome in the adult population and the most often refractory to medical therapy. |
2023-07-20 |
2023-08-14 |
mouse |
| Madhamanchi Kishore, Madhamanchi Pradeep, Parimala Narne, Sita Jayalakshmi, Manas Panigrahi, Anuja Patil, Phanithi Prakash Bab. Regulation of Keap-Nrf2 axis in temporal lobe epilepsy-hippocampal sclerosis patients may limit the seizure outcomes. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. 2023-07-11. PMID:37432566. |
our study focused on finding the factors influencing keap1-nrf2 axis regulation in temporal lobe epilepsy (tle) associated with hippocampal sclerosis (hs) patients. |
2023-07-11 |
2023-08-14 |
Not clear |
| Maureen Cassady, Gaston Basle. Dissociation in patients with epilepsy and functional seizures: A narrative review of the literature. Seizure. vol 110. 2023-07-11. PMID:37433243. |
ictal symptoms, especially in focal epilepsy of temporal lobe origin, may include dissociative-like experiences such as déjà vu/jamais vu, depersonalization, derealization and what has been described as a "dreamy state". these descriptions are common in the setting of seizures that originate from mesial temporal lobe epilepsy and may involve the amygdala and hippocampus. |
2023-07-11 |
2023-08-14 |
Not clear |
| Alice Ballerini, Francesca Talami, Maria Angela Molinari, Elisa Micalizzi, Simona Scolastico, Niccolò Biagioli, Niccolò Orlandi, Matteo Pugnaghi, Giada Giovannini, Stefano Meletti, Anna Elisabetta Vaudan. Exploring the relationship between amygdala subnuclei volumes and cognitive performance in left-lateralized temporal lobe epilepsy with and without hippocampal sclerosis. Epilepsy & behavior : E&B. vol 145. 2023-07-09. PMID:37422935. |
exploring the relationship between amygdala subnuclei volumes and cognitive performance in left-lateralized temporal lobe epilepsy with and without hippocampal sclerosis. |
2023-07-09 |
2023-08-14 |
Not clear |
| Chong Liu, Xue-Min Zhao, Qiao Wang, Ting-Ting Du, Mo-Xuan Zhang, Hui-Zhi Wang, Ren-Peng Li, Kun Liang, Yuan Gao, Si-Yu Zhou, Tao Xue, Jian-Guo Zhang, Chun-Lei Han, Lin Shi, Liang-Wen Zhang, Fan-Gang Men. Astrocyte-derived SerpinA3N promotes neuroinflammation and epileptic seizures by activating the NF-κB signaling pathway in mice with temporal lobe epilepsy. Journal of neuroinflammation. vol 20. issue 1. 2023-07-08. PMID:37422673. |
in our current study, transcriptomics analysis, proteomics analysis, and western blotting showed that the expression level of serpin clade a member 3n (serpina3n) is significantly increased in the hippocampus of mice with kainic acid (ka)-induced temporal lobe epilepsy, and this molecule is mainly expressed in astrocytes. |
2023-07-08 |
2023-08-14 |
mouse |
| Walter F De La Cruz Ramirez, Denisse E Chacón Zuñiga, Sofía S Sánchez Boluarte, Carlos M Vasquez Perez, Liza Núñez Del Prado Murillo, Jose C Delgado Rio. Postsurgical outcomes in a cohort of patients with hippocampal sclerosis. Initial experience in a referral epilepsy center in Peru. Epilepsia open. 2023-07-03. PMID:37394997. |
we performed a retrospective observational study included 91 patients with mesial temporal lobe epilepsy and hippocampal sclerosis who had undergone anterior temporal lobectomy between 2012 and 2020 at a surgical epilepsy center located in lima, peru. |
2023-07-03 |
2023-08-14 |
human |
| Ya He, Hongxia Zhang, Limin Ma, Jingang Li, Fei Wang, Hui Zhou, Guangliang Zhang, Yuetao We. Identification of TIMP1 as an inflammatory biomarker associated with temporal lobe epilepsy based on integrated bioinformatics and experimental analyses. Journal of neuroinflammation. vol 20. issue 1. 2023-06-26. PMID:37365625. |
temporal lobe epilepsy (tle) is the most common epilepsy subtype, and previous studies have reported that hippocampal inflammation is an important mechanism associated with the occurrence and development of tle. |
2023-06-26 |
2023-08-14 |
Not clear |
| Laura Fischbach, Tobias Bauer, Kersten Diers, Juri-Alexander Witt, Mar Brugues, Valeri Borger, Martin Schidlowski, Attila Rácz, Tobias Baumgartner, Randi von Wrede, Daniel Paech, Bernd Weber, Alexander Radbruch, Hartmut Vatter, Albert J Becker, Hans-Jürgen Huppertz, Christoph Helmstaedter, Rainer Surges, Martin Reuter, Theodor Rübe. A novel geometry-based analysis of hippocampal morphometry in mesial temporal lobe epilepsy. Human brain mapping. 2023-06-22. PMID:37347650. |
a novel geometry-based analysis of hippocampal morphometry in mesial temporal lobe epilepsy. |
2023-06-22 |
2023-08-14 |
human |
| Laura Fischbach, Tobias Bauer, Kersten Diers, Juri-Alexander Witt, Mar Brugues, Valeri Borger, Martin Schidlowski, Attila Rácz, Tobias Baumgartner, Randi von Wrede, Daniel Paech, Bernd Weber, Alexander Radbruch, Hartmut Vatter, Albert J Becker, Hans-Jürgen Huppertz, Christoph Helmstaedter, Rainer Surges, Martin Reuter, Theodor Rübe. A novel geometry-based analysis of hippocampal morphometry in mesial temporal lobe epilepsy. Human brain mapping. 2023-06-22. PMID:37347650. |
hippocampal volumetry is an essential tool in researching and diagnosing mesial temporal lobe epilepsy (mtle). |
2023-06-22 |
2023-08-14 |
human |
| Céline Boileau, Severine Deforges, Angélique Peret, Didier Scavarda, Fabrice Bartolomei, April Giles, Nicolas Partouche, Justine Gautron, Julio Viotti, Haley Janowitz, Guillaume Penchet, Cécile Marchal, Stanislas Lagarde, Agnès Trebuchon, Nathalie Villeneuve, Julie Rumi, Thomas Marissal, Roustem Khazipov, Ilgam Khalilov, Fanny Martineau, Marine Maréchal, Anne Lepine, Mathieu Milh, Dominique Figarella-Branger, Etienne Dougy, Soutsakhone Tong, Romain Appay, Stéphane Baudouin, Andrew Mercer, Jared B Smith, Olivier Danos, Richard Porter, Christophe Mulle, Valérie Crépe. GluK2 is a target for gene therapy in drug-resistant Temporal Lobe Epilepsy. Annals of neurology. 2023-06-21. PMID:37341588. |
temporal lobe epilepsy (tle) is characterized by recurrent seizures generated in the limbic system, particularly in the hippocampus. |
2023-06-21 |
2023-08-14 |
mouse |
| Arichena Manmatharayan, Michael Kogan, Caio Matias, Mashaal Syed, India Shelley, Amar Chinni, Kichang Kang, Kiran Talekar, Scott H Faro, Feroze B Mohamed, Ashwini Sharan, Chengyuan Wu, Mahdi Alizade. Automated subfield volumetric analysis of amygdala, hippocampus, and thalamic nuclei in mesial temporal lobe epilepsy. World neurosurgery: X. vol 19. 2023-06-12. PMID:37304157. |
automated subfield volumetric analysis of amygdala, hippocampus, and thalamic nuclei in mesial temporal lobe epilepsy. |
2023-06-12 |
2023-08-14 |
Not clear |
| Junzi Chen, Yu Wang, Cong Chen, Qingyang Zhang, Shuang Wang, Yi Wang, Jiajia Fang, Ying Wan. Activation of medial septum cholinergic neurons restores cognitive function in temporal lobe epilepsy. Neural regeneration research. vol 18. issue 11. 2023-06-07. PMID:37282477. |
cognitive impairment is the most common complication in patients with temporal lobe epilepsy with hippocampal sclerosis. |
2023-06-07 |
2023-08-14 |
mouse |
| Junzi Chen, Yu Wang, Cong Chen, Qingyang Zhang, Shuang Wang, Yi Wang, Jiajia Fang, Ying Wan. Activation of medial septum cholinergic neurons restores cognitive function in temporal lobe epilepsy. Neural regeneration research. vol 18. issue 11. 2023-06-07. PMID:37282477. |
in this study, we found that patients with temporal lobe epilepsy with hippocampal sclerosis had a low memory quotient and severe impairment in verbal memory, but had no impairment in nonverbal memory. |
2023-06-07 |
2023-08-14 |
mouse |
| Junzi Chen, Yu Wang, Cong Chen, Qingyang Zhang, Shuang Wang, Yi Wang, Jiajia Fang, Ying Wan. Activation of medial septum cholinergic neurons restores cognitive function in temporal lobe epilepsy. Neural regeneration research. vol 18. issue 11. 2023-06-07. PMID:37282477. |
in a mouse model of chronic temporal lobe epilepsy induced by kainic acid, the number of medial septum cholinergic neurons was reduced and acetylcholine release was reduced in the hippocampus. |
2023-06-07 |
2023-08-14 |
mouse |
| Junzi Chen, Yu Wang, Cong Chen, Qingyang Zhang, Shuang Wang, Yi Wang, Jiajia Fang, Ying Wan. Activation of medial septum cholinergic neurons restores cognitive function in temporal lobe epilepsy. Neural regeneration research. vol 18. issue 11. 2023-06-07. PMID:37282477. |
these results suggest that activation of medial septum cholinergic neurons reduces cognitive deficits in temporal lobe epilepsy by increasing acetylcholine release via projections to the hippocampus. |
2023-06-07 |
2023-08-14 |
mouse |
| Keran Ma, Xiaonan Zhang, Chengru Song, Shaoqiang Han, Wenbin Li, Kefan Wang, Xinyue Mao, Yong Zhang, Jingliang Chen. Altered topological properties and their relationship to cognitive functions in unilateral temporal lobe epilepsy. Epilepsy & behavior : E&B. vol 144. 2023-06-02. PMID:37267843. |
to investigate abnormalities in topological properties in unilateral temporal lobe epilepsy (tle) with hippocampal sclerosis and their correlations with cognitive functions. |
2023-06-02 |
2023-08-14 |
Not clear |
| Jingwen Jiang, Jiajun Qiu, Jin Yin, Junren Wang, Xinyue Jiang, Zuo Yi, Yang Chen, Xiaobo Zhou, Xiutian Sim. Automated detection of hippocampal sclerosis using real-world clinical MRI images. Frontiers in neuroscience. vol 17. 2023-05-31. PMID:37255750. |
hippocampal sclerosis (hs) is the most common pathological type of temporal lobe epilepsy (tle) and one of the important surgical markers. |
2023-05-31 |
2023-08-14 |
Not clear |
| Cathryn A Cutia, Leanna K Leverton, Catherine A Christian-Hinma. Sex and estrous cycle stage shape left-right asymmetry in chronic hippocampal seizures in mice. eNeuro. 2023-05-29. PMID:37248046. |
lateralization of hippocampal function is indicated by varied outcomes of patients with neurological disorders that selectively affect one hemisphere of this structure, such as temporal lobe epilepsy (tle). |
2023-05-29 |
2023-08-14 |
mouse |
| Kishore Madhamanchi, Pradeep Madhamanchi, Sita Jayalakshmi, Manas Panigrahi, Anuja Patil, Prakash Babu Phanith. Dopamine and Glutamate Crosstalk Worsen the Seizure Outcome in TLE-HS Patients. Molecular neurobiology. 2023-05-20. PMID:37209264. |
temporal lobe epilepsy (tle), accompanied by hippocampal sclerosis (hs), is the most common form of drug-resistant epilepsy (dre). |
2023-05-20 |
2023-08-14 |
Not clear |
| Ricardo Insausti, Monica Muñoz-López, Ana Maria Insaust. The CA2 hippocampal subfield in humans: A review. Hippocampus. 2023-05-19. PMID:37204159. |
human ca2 is subject of neuropathological studies, and we chose to present alzheimer's disease, schizophrenia, and mesial temporal lobe epilepsy with hippocampal sclerosis in those aspects that impinge directly into ca2. |
2023-05-19 |
2023-08-14 |
human |