| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shiva Keihaninejad, Rolf A Heckemann, Ioannis S Gousias, Joseph V Hajnal, John S Duncan, Paul Aljabar, Daniel Rueckert, Alexander Hammer. Classification and lateralization of temporal lobe epilepsies with and without hippocampal atrophy based on whole-brain automatic MRI segmentation. PloS one. vol 7. issue 4. 2012-08-03. PMID:22523539. |
we sought to identify morphometric criteria for distinguishing controls (n = 28) from patients with unilateral temporal lobe epilepsy (tle), 60 with and 20 without hippocampal atrophy (tle-ha and tle-n, respectively), and for determining the presumed side of seizure onset. |
2012-08-03 |
2023-08-12 |
human |
| Xiao-Liang Xing, Long-Ze Sha, Yuan Yao, Yan Shen, Li-Wen Wu, Qi X. Spatio-temporal expression study of phosphorylated 70-kDa ribosomal S6 kinase (p70S6k) in mesial temporal lobe epilepsy. Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih. vol 27. issue 1. 2012-07-24. PMID:22734207. |
to determine the spatio-temporal expression of p70s6k activation in hippocampus in mesial temporal lobe epilepsy. |
2012-07-24 |
2023-08-12 |
Not clear |
| Masae Ryufuku, Yasuko Toyoshima, Hiroki Kitaura, Yingjun Zheng, Yong-Juan Fu, Hiroaki Miyahara, Hiroatsu Murakami, Hiroshi Masuda, Shigeki Kameyama, Hitoshi Takahashi, Akiyoshi Kakit. Hypertrophy of hippocampal end folium neurons in patients with mesial temporal lobe epilepsy. Neuropathology : official journal of the Japanese Society of Neuropathology. vol 31. issue 5. 2012-07-23. PMID:21276083. |
hypertrophy of hippocampal end folium neurons in patients with mesial temporal lobe epilepsy. |
2012-07-23 |
2023-08-12 |
Not clear |
| Masae Ryufuku, Yasuko Toyoshima, Hiroki Kitaura, Yingjun Zheng, Yong-Juan Fu, Hiroaki Miyahara, Hiroatsu Murakami, Hiroshi Masuda, Shigeki Kameyama, Hitoshi Takahashi, Akiyoshi Kakit. Hypertrophy of hippocampal end folium neurons in patients with mesial temporal lobe epilepsy. Neuropathology : official journal of the Japanese Society of Neuropathology. vol 31. issue 5. 2012-07-23. PMID:21276083. |
hypertrophic and dysmorphic neurons have been identified in the hippocampal end folium of patients with mesial temporal lobe epilepsy (mtle). |
2012-07-23 |
2023-08-12 |
Not clear |
| Masae Ryufuku, Yasuko Toyoshima, Hiroki Kitaura, Yingjun Zheng, Yong-Juan Fu, Hiroaki Miyahara, Hiroatsu Murakami, Hiroshi Masuda, Shigeki Kameyama, Hitoshi Takahashi, Akiyoshi Kakit. Hypertrophy of hippocampal end folium neurons in patients with mesial temporal lobe epilepsy. Neuropathology : official journal of the Japanese Society of Neuropathology. vol 31. issue 5. 2012-07-23. PMID:21276083. |
we evaluated both the perikaryon and nuclear areas of residual neurons in the hippocampal end folium of 47 patients with mtle, seven with lesional neocortical temporal lobe epilepsy (ltle), and 10 controls without seizure episodes. |
2012-07-23 |
2023-08-12 |
Not clear |
| Günther Sperk, Anna Wieselthaler-Hölzl, Susanne Pirker, Ramon Tasan, Sarah S Strasser, Meinrad Drexel, Christian Pifl, Julian Marschalek, Martin Ortler, Eugen Trinka, Katja Heitmair-Wietzorrek, Philippe Ciofi, Martha Feucht, Christoph Baumgartner, Thomas Czec. Glutamate decarboxylase 67 is expressed in hippocampal mossy fibers of temporal lobe epilepsy patients. Hippocampus. vol 22. issue 3. 2012-07-23. PMID:21509853. |
glutamate decarboxylase 67 is expressed in hippocampal mossy fibers of temporal lobe epilepsy patients. |
2012-07-23 |
2023-08-12 |
rat |
| Günther Sperk, Anna Wieselthaler-Hölzl, Susanne Pirker, Ramon Tasan, Sarah S Strasser, Meinrad Drexel, Christian Pifl, Julian Marschalek, Martin Ortler, Eugen Trinka, Katja Heitmair-Wietzorrek, Philippe Ciofi, Martha Feucht, Christoph Baumgartner, Thomas Czec. Glutamate decarboxylase 67 is expressed in hippocampal mossy fibers of temporal lobe epilepsy patients. Hippocampus. vol 22. issue 3. 2012-07-23. PMID:21509853. |
here, we investigated the expression of gad67 protein and mrna in 44 hippocampal specimens from patients with mesial temporal lobe epilepsy (tle) using double immunofluorescence histochemistry, immunoblotting, and in situ hybridization. |
2012-07-23 |
2023-08-12 |
rat |
| P Elyse Schauwecke. Strain differences in seizure-induced cell death following pilocarpine-induced status epilepticus. Neurobiology of disease. vol 45. issue 1. 2012-07-23. PMID:21878392. |
in rodents, the cholinomimetic convulsant pilocarpine is widely used to induce status epilepticus (se), followed by hippocampal damage and spontaneous recurrent seizures, resembling temporal lobe epilepsy. |
2012-07-23 |
2023-08-12 |
mouse |
| L Martinian, C B Catarino, P Thompson, S M Sisodiya, M Tho. Calbindin D28K expression in relation to granule cell dispersion, mossy fibre sprouting and memory impairment in hippocampal sclerosis: a surgical and post mortem series. Epilepsy research. vol 98. issue 1. 2012-07-19. PMID:21920703. |
reorganisation of the dentate gyrus, including granule cell dispersion (gcd) and mossy fibre sprouting, typically accompany hippocampal sclerosis (hs) in temporal lobe epilepsy. |
2012-07-19 |
2023-08-12 |
Not clear |
| Shanting Zhao, Daniel Studer, Werner Graber, Sigrun Nestel, Michael Frotsche. Fine structure of hippocampal mossy fiber synapses following rapid high-pressure freezing. Epilepsia. vol 53 Suppl 1. 2012-07-16. PMID:22612803. |
synapses of hippocampal neurons play important roles in learning and memory processes and are involved in aberrant hippocampal function in temporal lobe epilepsy. |
2012-07-16 |
2023-08-12 |
Not clear |
| Patricia Szo. Common factors among Alzheimer's disease, Parkinson's disease, and epilepsy: possible role of the noradrenergic nervous system. Epilepsia. vol 53 Suppl 1. 2012-07-16. PMID:22612810. |
epilepsy is not considered a neurodegenerative disorder, but the hippocampus is severely affected in temporal lobe epilepsy. |
2012-07-16 |
2023-08-12 |
Not clear |
| Hosung Kim, Marie Chupin, Olivier Colliot, Boris C Bernhardt, Neda Bernasconi, Andrea Bernascon. Automatic hippocampal segmentation in temporal lobe epilepsy: impact of developmental abnormalities. NeuroImage. vol 59. issue 4. 2012-07-03. PMID:22155377. |
automatic hippocampal segmentation in temporal lobe epilepsy: impact of developmental abnormalities. |
2012-07-03 |
2023-08-12 |
human |
| Hosung Kim, Marie Chupin, Olivier Colliot, Boris C Bernhardt, Neda Bernasconi, Andrea Bernascon. Automatic hippocampal segmentation in temporal lobe epilepsy: impact of developmental abnormalities. NeuroImage. vol 59. issue 4. 2012-07-03. PMID:22155377. |
in drug-resistant temporal lobe epilepsy (tle), detecting hippocampal atrophy on mri is important as it allows defining the surgical target. |
2012-07-03 |
2023-08-12 |
human |
| Jason L Stein, Sarah E Medland, Alejandro Arias Vasquez, Derrek P Hibar, Rudy E Senstad, Anderson M Winkler, Roberto Toro, Katja Appel, Richard Bartecek, Ørjan Bergmann, Manon Bernard, Andrew A Brown, Dara M Cannon, M Mallar Chakravarty, Andrea Christoforou, Martin Domin, Oliver Grimm, Marisa Hollinshead, Avram J Holmes, Georg Homuth, Jouke-Jan Hottenga, Camilla Langan, Lorna M Lopez, Narelle K Hansell, Kristy S Hwang, Sungeun Kim, Gonzalo Laje, Phil H Lee, Xinmin Liu, Eva Loth, Anbarasu Lourdusamy, Morten Mattingsdal, Sebastian Mohnke, Susana Muñoz Maniega, Kwangsik Nho, Allison C Nugent, Carol O'Brien, Martina Papmeyer, Benno Pütz, Adaikalavan Ramasamy, Jerod Rasmussen, Mark Rijpkema, Shannon L Risacher, J Cooper Roddey, Emma J Rose, Mina Ryten, Li Shen, Emma Sprooten, Eric Strengman, Alexander Teumer, Daniah Trabzuni, Jessica Turner, Kristel van Eijk, Theo G M van Erp, Marie-Jose van Tol, Katharina Wittfeld, Christiane Wolf, Saskia Woudstra, Andre Aleman, Saud Alhusaini, Laura Almasy, Elisabeth B Binder, David G Brohawn, Rita M Cantor, Melanie A Carless, Aiden Corvin, Michael Czisch, Joanne E Curran, Gail Davies, Marcio A A de Almeida, Norman Delanty, Chantal Depondt, Ravi Duggirala, Thomas D Dyer, Susanne Erk, Jesen Fagerness, Peter T Fox, Nelson B Freimer, Michael Gill, Harald H H Göring, Donald J Hagler, David Hoehn, Florian Holsboer, Martine Hoogman, Norbert Hosten, Neda Jahanshad, Matthew P Johnson, Dalia Kasperaviciute, Jack W Kent, Peter Kochunov, Jack L Lancaster, Stephen M Lawrie, David C Liewald, René Mandl, Mar Matarin, Manuel Mattheisen, Eva Meisenzahl, Ingrid Melle, Eric K Moses, Thomas W Mühleisen, Matthias Nauck, Markus M Nöthen, Rene L Olvera, Massimo Pandolfo, G Bruce Pike, Ralf Puls, Ivar Reinvang, Miguel E Rentería, Marcella Rietschel, Joshua L Roffman, Natalie A Royle, Dan Rujescu, Jonathan Savitz, Hugo G Schnack, Knut Schnell, Nina Seiferth, Colin Smith, Vidar M Steen, Maria C Valdés Hernández, Martijn Van den Heuvel, Nic J van der Wee, Neeltje E M Van Haren, Joris A Veltman, Henry Völzke, Robert Walker, Lars T Westlye, Christopher D Whelan, Ingrid Agartz, Dorret I Boomsma, Gianpiero L Cavalleri, Anders M Dale, Srdjan Djurovic, Wayne C Drevets, Peter Hagoort, Jeremy Hall, Andreas Heinz, Clifford R Jack, Tatiana M Foroud, Stephanie Le Hellard, Fabio Macciardi, Grant W Montgomery, Jean Baptiste Poline, David J Porteous, Sanjay M Sisodiya, John M Starr, Jessika Sussmann, Arthur W Toga, Dick J Veltman, Henrik Walter, Michael W Weiner, Joshua C Bis, M Arfan Ikram, Albert V Smith, Vilmundur Gudnason, Christophe Tzourio, Meike W Vernooij, Lenore J Launer, Charles DeCarli, Sudha Seshadri, Ole A Andreassen, Liana G Apostolova, Mark E Bastin, John Blangero, Han G Brunner, Randy L Buckner, Sven Cichon, Giovanni Coppola, Greig I de Zubicaray, Ian J Deary, Gary Donohoe, Eco J C de Geus, Thomas Espeseth, Guillén Fernández, David C Glahn, Hans J Grabe, John Hardy, Hilleke E Hulshoff Pol, Mark Jenkinson, René S Kahn, Colm McDonald, Andrew M McIntosh, Francis J McMahon, Katie L McMahon, Andreas Meyer-Lindenberg, Derek W Morris, Bertram Müller-Myhsok, Thomas E Nichols, Roel A Ophoff, Tomas Paus, Zdenka Pausova, Brenda W Penninx, Steven G Potkin, Philipp G Sämann, Andrew J Saykin, Gunter Schumann, Jordan W Smoller, Joanna M Wardlaw, Michael E Weale, Nicholas G Martin, Barbara Franke, Margaret J Wright, Paul M Thompso. Identification of common variants associated with human hippocampal and intracranial volumes. Nature genetics. vol 44. issue 5. 2012-07-02. PMID:22504417. |
the volume of the hippocampus is a biomarker of incipient alzheimer's disease and is reduced in schizophrenia, major depression and mesial temporal lobe epilepsy. |
2012-07-02 |
2023-08-12 |
human |
| Nicola Berretta, Ada Ledonne, Dalila Mango, Giorgio Bernardi, Nicola B Mercur. Hippocampus versus entorhinal cortex decoupling by an NR2 subunit-specific block of NMDA receptors in a rat in vitro model of temporal lobe epilepsy. Epilepsia. vol 53. issue 5. 2012-06-18. PMID:22360154. |
hippocampus versus entorhinal cortex decoupling by an nr2 subunit-specific block of nmda receptors in a rat in vitro model of temporal lobe epilepsy. |
2012-06-18 |
2023-08-12 |
rat |
| Brian L Murphy, Rylon D Hofacer, Christian N Faulkner, Andreas W Loepke, Steve C Danze. Abnormalities of granule cell dendritic structure are a prominent feature of the intrahippocampal kainic acid model of epilepsy despite reduced postinjury neurogenesis. Epilepsia. vol 53. issue 5. 2012-06-18. PMID:22533643. |
aberrant plastic changes among adult-generated hippocampal dentate granule cells are hypothesized to contribute to the development of temporal lobe epilepsy. |
2012-06-18 |
2023-08-12 |
Not clear |
| Riitta Miettinen, Tibor Hajszan, Anett Riedel, Klara Szigeti-Buck, Csaba Lerant. Estimation of the total number of hippocampal CA1 pyramidal neurons: new methodology applied to helpless rats. Journal of neuroscience methods. vol 205. issue 1. 2012-06-15. PMID:22230770. |
our method provides an improved tool for studies aiming to evaluate hippocampal atrophy and cell loss, the most characteristic features in many neurodegenerative diseases, such as alzheimer's disease, temporal lobe epilepsy and ischemia, as well as in several psychiatric disorders. |
2012-06-15 |
2023-08-12 |
rat |
| Dong Wook Kim, Sang Kun Lee, Chun Kee Chung, Young-Cho Koh, Geeyoung Choe, So Dug Li. Clinical features and pathological characteristics of amygdala enlargement in mesial temporal lobe epilepsy. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. vol 19. issue 4. 2012-06-15. PMID:22321366. |
although the hippocampus is considered an important site of seizures in mesial temporal lobe epilepsy (mtle), the amygdala may also have a significant role. |
2012-06-15 |
2023-08-12 |
Not clear |
| Heather Wilkinson, Juliet S Holdstock, Gus Baker, Andrea Herbert, Fiona Clague, John J Downe. Long-term accelerated forgetting of verbal and non-verbal information in temporal lobe epilepsy. Cortex; a journal devoted to the study of the nervous system and behavior. vol 48. issue 3. 2012-05-25. PMID:21397222. |
we investigated whether pre-surgical patients with temporal lobe epilepsy (tle) forget verbal and non-verbal material faster than healthy controls over retention intervals of an hour and 6 weeks, and whether any observed memory loss was associated with structural changes to the hippocampus and/or seizure frequency. |
2012-05-25 |
2023-08-12 |
Not clear |
| R M Busch, T Frazier, J S Chapin, A H Hamrahian, B Diehl, A Alexopoulos, K Unnwongse, R I Naugle, C S Kubu, G E Tesar, I M Naj. Role of cortisol in mood and memory in patients with intractable temporal lobe epilepsy. Neurology. vol 78. issue 14. 2012-05-18. PMID:22442430. |
this study prospectively examined the relationships among late night salivary cortisol (nsc) levels and depressive symptoms, memory performance, and hippocampal volumes in patients with medically intractable temporal lobe epilepsy (tle) and the potential mediating effects of cortisol in the relationships between these variables. |
2012-05-18 |
2023-08-12 |
Not clear |