All Relations between Neurodegenerative Diseases and microtubule-associated protein tau

Reference Sentence Publish Date Extraction Date Species
Helen C Murray, Chelsie Osterman, Paige Bell, Luca Vinnell, Maurice A Curti. Neuropathology in chronic traumatic encephalopathy: a systematic review of comparative post-mortem histology literature. Acta neuropathologica communications vol 10 issue 1 2022 35933388 chronic traumatic encephalopathy (cte) is a neurodegenerative disease associated with repetitive head trauma and is characterised by the perivascular accumulation of hyperphosphorylated tau (p-tau) in the depths of cortical sulci. 2022-08-06 2022-08-08 Not clear
Alexandria B Marciante, John Howard, Mia N Kelly, Juan Santiago Moreno, Latoya L Allen, Elisa J Gonzalez-Rothi, Gordon S Mitchel. Dose-dependent Phosphorylation of Endogenous Tau by Intermittent Hypoxia in Rat Brain. Journal of applied physiology (Bethesda, Md. : 1985) vol issue 2022 35861520 sleep apnea is comorbid in >50% of patients with alzheimer's disease-a progressive, neurodegenerative disease associated with brain amyloid and chronic tau dysregulation (pathology). 2022-07-21 2022-07-25 Not clear
Cong Li. The Role of Mesenchymal Stem Cells in Regulating Astrocytes-Related Synapse Dysfunction in Early Alzheimer's Disease. Frontiers in neuroscience vol 16 issue 2022 35801178 alzheimer's disease (ad), a neurodegenerative disease, is characterized by the presence of extracellular amyloid-\xce\xb2 (a\xce\xb2) aggregates and intracellular neurofibrillary tangles formed by hyperphosphorylated tau as pathological features and the cognitive decline as main clinical features. 2022-07-08 2022-07-11 Not clear
Erpan Ahat, Sarah Bui, Jianchao Zhang, Felipe da Veiga Leprevost, Lisa Sharkey, Whitney Reid, Alexey I Nesvizhskii, Henry L Paulson, Yanzhuang Wan. GRASP55 regulates the unconventional secretion and aggregation of mutant huntingtin. The Journal of biological chemistry vol issue 2022 35780830 here, we surveyed several neurodegenerative disease related proteins, including mutant huntingtin (htt-q74), sod1, tau, and tdp43, for unconventional secretion; our results show that htt-q74 is most robustly secreted in a grasp55-dependent manner. 2022-07-05 2022-07-07 Not clear
Lara Bl\\xc3\\xb6meke, Marlene Pils, Victoria Kraemer-Schulien, Alexandra Dybala, Anja Schaffrath, Andreas Kulawik, Fabian Rehn, Anneliese Cousin, Volker Nischwitz, Johannes Willbold, Rebecca Zack, Thomas F Tropea, Tuyen Bujnicki, G\\xc3\\xbcltekin Tamg\\xc3\\xbcney, Daniel Weintraub, David Irwin, Murray Grossman, David A Wolk, John Q Trojanowski, Oliver Bannach, Alice Chen-Plotkin, Dieter Willbol. Quantitative detection of \\xce\\xb1-Synuclein and Tau oligomers and other aggregates by digital single particle counting. NPJ Parkinson's disease vol 8 issue 1 2022 35655068 our results demonstrate that asyn and tau aggregate concentrations measured by sfida differentiate neurodegenerative disease diagnostic groups. 2022-06-02 2022-06-13 Not clear
Vera I Wiersma, Ruben Rigort, Magdalini Polymenido. Tau: a phase in the crowd. The EMBO journal vol issue 2022 35578810 from the management of microtubules to the production of pathological species: liquid-liquid phase separation may tune the behavior of the protein tau in health and neurodegenerative disease. 2022-05-17 2022-06-13 Not clear
S Tok, H Maurin, C Delay, D Crauwels, N V Manyakov, W Van Der Elst, D Moechars, W H I M Drinkenbur. Neurophysiological effects of human-derived pathological tau conformers in the APPKM670/671NL.PS1/L166P amyloid mouse model of Alzheimer's disease. Scientific reports vol 12 issue 1 2022 35546164 alzheimer's disease (ad) is a neurodegenerative disease characterized by two main pathological hallmarks: amyloid plaques and intracellular tau neurofibrillary tangles. 2022-05-13 2022-06-13 Not clear
Ishani Pidara, Koyuki Yamad. The Structure of Tau Proteins and Its Role in Neurodegenerative Disease. FASEB journal : official publication of the Federation of American Societies for Experimental Biology vol 36 Suppl 1 issue 2022 35553522 the structure of tau proteins and its role in neurodegenerative disease. 2022-05-13 2022-06-13 Not clear
Yongle Cai, Jingliu Liu, Bin Wang, Miao Sun, Hao Yan. Microglia in the Neuroinflammatory Pathogenesis of Alzheimer's Disease and Related Therapeutic Targets. Frontiers in immunology vol 13 issue 2022 35558075 alzheimer's disease (ad) is the most prevalent neurodegenerative disease worldwide, characterized by progressive neuron degeneration or loss due to excessive accumulation of \xce\xb2-amyloid (a\xce\xb2) peptides, formation of neurofibrillary tangles (nfts), and hyperphosphorylated tau. 2022-05-13 2022-06-13 Not clear
Filipa Gouveia, Antoni Camins, Miren Ettcheto, Joana Bicker, Am\\xc3\\xadlcar Falc\\xc3\\xa3o, M Teresa Cruz, Ana Fortun. Targeting Brain Renin-Angiotensin System for the prevention and treatment of Alzheimer's disease: past, present and future. Ageing research reviews vol issue 2022 35346852 alzheimer's disease (ad) is a well-known neurodegenerative disease characterized by the presence of two main hallmarks - tau hyperphosphorylation and a\xce\xb2 deposits. 2022-03-29 2022-04-14 Not clear
Haiqiong Ye, Yue Han, Ping Li, Zhengding Su, Yongqi Huan. The Role of Post-Translational Modifications on the Structure and Function of Tau Protein. Journal of molecular neuroscience : MN vol issue 2022 35325356 accumulated evidence shows that these ptms play a critical role in regulating tau-microtubule interaction, tau localization, tau degradation and aggregation, and reinforces the correlation between tau ptms and pathogenesis of neurodegenerative disease. 2022-03-24 2022-04-14 Not clear
Thibaut Gauvrit, Hamza Benderradji, Luc Bu\\xc3\\xa9e, David Blum, Didier Viea. Early-Life Environment Influence on Late-Onset Alzheimer's Disease. Frontiers in cell and developmental biology vol 10 issue 2022 35252195 alzheimer disease (ad) which is the most prevalent neurodegenerative disease is mostly sporadic and primarily characterized by cognitive deficits and neuropathological lesions such as amyloid -\xce\xb2 (a\xce\xb2) plaques and neurofibrillary tangles composed of hyper- and/or abnormally phosphorylated tau protein. 2022-03-08 2022-03-09 Not clear
Thibaut Gauvrit, Hamza Benderradji, Luc Bu\\xc3\\xa9e, David Blum, Didier Viea. Early-Life Environment Influence on Late-Onset Alzheimer's Disease. Frontiers in cell and developmental biology vol 10 issue 2022 35252195 alzheimer disease (ad) which is the most prevalent neurodegenerative disease is mostly sporadic and primarily characterized by cognitive deficits and neuropathological lesions such as amyloid -\xce\xb2 (a\xce\xb2) plaques and neurofibrillary tangles composed of hyper- and/or abnormally phosphorylated tau protein. 2022-03-07 2022-03-09 Not clear
Solomiia Boyko, Witold K Surewic. Tau liquid-liquid phase separation in neurodegenerative diseases. Trends in cell biology vol issue 2022 35181198 an exciting recent development is the finding that, akin to some other proteins associated with neurodegenerative disease, tau has a high propensity to condensate via the mechanism of liquid-liquid phase separation (llps). 2022-02-19 2022-02-23 Not clear
Baofeng Gong, Wenbo Ji, Xiaohan Chen, Peng Li, Wenbin Cheng, Yuchen Zhao, Bin He, Jianhua Zhuang, Jie Gao, You Yi. Recent Advancements in Strategies for Abnormal Protein Clearance in Alzheimer's Disease. Mini reviews in medicinal chemistry vol issue 2022 35156576 alzheimer's disease (ad) is a intricate neurodegenerative disease with chronic and progressive development whose typical neuropathological features encompasses senile plaques and neurofibrillary tangles respectively formed by the extracellular deposition of amyloid-beta (a\xce\xb2) and the intracellular accumulation of hyperphosphorylated tau protein in the brain, particularly in limbic and cortical regions. 2022-02-14 2022-02-17 Not clear
Kemeng Pan, Song Chen, Yue Wang, Wenbing Yao, Xiangdong Ga. MicroRNA-23b attenuates tau pathology and inhibits oxidative stress by targeting GnT-III in Alzheimer's disease. Neuropharmacology vol 196 issue 2021 34153312 alzheimer's disease (ad) is a neurodegenerative disease, the main pathological features include deposition of neurofibrillary tangles composed of the abnormally hyperphosphorylated tau protein and plaques deposition composed of \xce\xb2-amyloid (a\xce\xb2) peptide. 2022-02-02 2022-01-13 Not clear
Kaoru Yagita, Hiroyuki Honda, Tomoyuki Ohara, Hideomi Hamasaki, Sachiko Koyama, Hideko Noguchi, Akane Mihara, Taro Nakazawa, Jun Hata, Toshiharu Ninomiya, Toru Iwak. A Comparative Study of Site-Specific Distribution of Aging-Related Tau Astrogliopathy and Its Risk Factors Between Alzheimer Disease and Cognitive Healthy Brains: The Hisayama Study. Journal of neuropathology and experimental neurology vol issue 2021 34875089 knowledge of aging-related tau astrogliopathy (artag) in healthy elderly individuals remains incomplete and studies to date have not focused on the olfactory nerve, which is a vulnerable site of various neurodegenerative disease pathologies. 2022-01-31 2022-01-13 Not clear
Bin Tang, Wu Zeng, Lin Lin Song, Hui Miao Wang, Li Qun Qu, Hang Hong Lo, Lu Yu, An Guo Wu, Vincent Kam Wai Wong, Betty Yuen Kwan La. Extracellular Vesicle Delivery of Neferine for the Attenuation of Neurodegenerative Disease Proteins and Motor Deficit in an Alzheimer's Disease Mouse Model. Pharmaceuticals (Basel, Switzerland) vol 15 issue 1 2022 35056140 in vitro cellular models confirmed that three of the selected exosome-encapsulated natural compounds-baicalin, hederagenin and neferine-could reduce the level of neurodegenerative disease mutant proteins-including huntingtin 74 (htt74), p301l tau and a53t \xce\xb1-synuclein (a53t \xce\xb1-syn)-more effectively than the compounds alone. 2022-01-28 2022-01-27 Not clear
Bin Tang, Wu Zeng, Lin Lin Song, Hui Miao Wang, Li Qun Qu, Hang Hong Lo, Lu Yu, An Guo Wu, Vincent Kam Wai Wong, Betty Yuen Kwan La. Extracellular Vesicle Delivery of Neferine for the Attenuation of Neurodegenerative Disease Proteins and Motor Deficit in an Alzheimer's Disease Mouse Model. Pharmaceuticals (Basel, Switzerland) vol 15 issue 1 2022 35056140 in vitro cellular models confirmed that three of the selected exosome-encapsulated natural compounds-baicalin, hederagenin and neferine-could reduce the level of neurodegenerative disease mutant proteins-including huntingtin 74 (htt74), p301l tau and a53t \xce\xb1-synuclein (a53t \xce\xb1-syn)-more effectively than the compounds alone. 2022-01-21 2022-01-27 Not clear
Martin J Dahl, Mara Mather, Markus Werkle-Bergner, Briana L Kennedy, Samuel Guzman, Kyle Hurth, Carol A Miller, Yuchuan Qiao, Yonggang Shi, Helena C Chui, John M Ringma. Locus coeruleus integrity is related to tau burden and memory loss in autosomal-dominant Alzheimer's disease. Neurobiology of aging vol 112 issue 2022 35045380 our findings link lc degeneration to tau burden and memory in alzheimer's, and highlight a role of the noradrenergic system in this neurodegenerative disease. 2022-01-19 2022-01-27 Not clear
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