All Relations between Neurodegenerative Diseases and microtubule-associated protein tau

Publication Sentence Publish Date Extraction Date Species
Bastien Herli. Hippocampal sclerosis linked to epilepsy: clinical consequences, histopathology and evolution with aging Geriatrie et psychologie neuropsychiatrie du vieillissement. vol 20. issue 4. 2023-01-26. PMID:36700444. those deposits pattern is close to the one observed in patients with tau / amyloïd neurodegenerative diseases, which demonstrates a bilateral relationship between epilepsy, hippocampal sclerosis, and neurodegenerative diseases. 2023-01-26 2023-08-14 human
Aleksandra Parka, Caroline Degel, Jakob Dreyer, Ulrike Richter, Benjamin Hall, Jesper F Bastlund, Bettina Laursen, Maiken Nedergaard, Florence Sotty, Paolo Bott. Early impairments of visually-driven neuronal ensemble dynamics in the rTg4510 tauopathy mouse model. Neurobiology of disease. vol 178. 2023-01-25. PMID:36696792. tau protein pathology is a hallmark of many neurodegenerative diseases, including alzheimer's disease or frontotemporal dementia. 2023-01-25 2023-08-14 mouse
Rebeccah J Katzenberger, Barry Ganetzky, David A Wassarma. Lissencephaly-1 mutations enhance traumatic brain injury outcomes in Drosophila. Genetics. 2023-01-23. PMID:36683334. these data suggest that lis-1 activity is required in the brain to ameliorate tbi outcomes through effects on axonal transport, microtubule stability, and other microtubule proteins such as tau, implicated in chronic traumatic encephalopathy, a tbi-associated neurodegenerative disease in humans. 2023-01-23 2023-08-14 drosophila_melanogaster
Iftakher Hossain, Kaj Blennow, Jussi P Posti, Henrik Zetterber. Tau as a fluid biomarker of concussion and neurodegeneration. Concussion (London, England). vol 7. issue 2. 2023-01-23. PMID:36687115. here, we discuss the diagnostic dilemma and the relationship between concussion and neurodegenerative diseases and review the literature on tau as a promising biomarker for concussion. 2023-01-23 2023-08-14 Not clear
Jingxin Chen, Wanyao Ma, Jiangchuan Yu, Xi Wang, Hongling Qian, Ping Li, Haiqiong Ye, Yue Han, Zhengding Su, Meng Gao, Yongqi Huan. (-)-Epigallocatechin-3-gallate, a Polyphenol from Green Tea, Regulates the Liquid-Liquid Phase Separation of Alzheimer's-Related Protein Tau. Journal of agricultural and food chemistry. 2023-01-23. PMID:36688583. complementary to the inhibitory activity of egcg in tau fibrillization, our findings provide novel insights into the biological activity of egcg and offer new clues for future studies on the molecular mechanism by which egcg alleviates neurodegenerative diseases. 2023-01-23 2023-08-14 Not clear
Deonne Taylor, Andrew Kneynsberg, Marloes van Roijen, Jürgen Göt. Tyrosine phosphatase STEP Molecular brain. vol 16. issue 1. 2023-01-13. PMID:36639708. tyrosine phosphatase step synaptic degeneration is a precursor of synaptic and neuronal loss in neurodegenerative diseases such as alzheimer's disease (ad) and frontotemporal dementia with tau pathology (ftd-tau), a group of primary tauopathies. 2023-01-13 2023-08-14 Not clear
Jianing Jin, Dongning Su, Junjiao Zhang, Xiaohong Li, Tao Fen. Tau PET imaging in progressive supranuclear palsy: a systematic review and meta-analysis. Journal of neurology. 2023-01-12. PMID:36633672. to evaluate the difference of tau burden between patients with progressive supranuclear palsy (psp) and healthy controls (hcs) or other neurodegenerative diseases using tau-positron emission tomography (pet) imaging. 2023-01-12 2023-08-14 Not clear
Evan Lester, Meaghan Van Alstyne, Kathleen L McCann, Spoorthy Reddy, Li Yi Cheng, Jeff Kuo, James Pratt, Roy Parke. Cytosolic condensates rich in polyserine define subcellular sites of tau aggregation. Proceedings of the National Academy of Sciences of the United States of America. vol 120. issue 3. 2023-01-10. PMID:36626563. tau aggregates are a hallmark of multiple neurodegenerative diseases and can contain rnas and rna-binding proteins, including serine/arginine repetitive matrix protein 2 (srrm2) and pinin (pnn). 2023-01-10 2023-08-14 Not clear
Evan Lester, Meaghan Van Alstyne, Kathleen L McCann, Spoorthy Reddy, Li Yi Cheng, Jeff Kuo, James Pratt, Roy Parke. Cytosolic condensates rich in polyserine define subcellular sites of tau aggregation. Proceedings of the National Academy of Sciences of the United States of America. vol 120. issue 3. 2023-01-10. PMID:36626563. as css form in induced pluripotent stem cell (ipsc) derived neurons under inflammatory or hyperosmolar stress, they may affect tau aggregate propagation in neurodegenerative disease. 2023-01-10 2023-08-14 Not clear
Xin Liu, Weiyi She, Herman H-Y Sung, Ian D Williams, Peiyuan Qia. Tau-aggregation inhibitors derived from Streptomyces tendae MCCC 1A01534 protect HT22 cells against okadaic acid-induced damage. International journal of biological macromolecules. 2023-01-09. PMID:36621732. alzheimer's disease (ad) is an age-related neurodegenerative disease characterized by tau aggregating into neurofibrillary tangles. 2023-01-09 2023-08-14 Not clear
Natalia Pieńkowska, Margaret Fahnestock, Crystal Mahadeo, Izabela Zaborniak, Paweł Chmielarz, Grzegorz Bartosz, Izabela Sadowska-Bartos. Induction of Oxidative Stress in SH-SY5Y Cells by Overexpression of hTau40 and Its Mitigation by Redox-Active Nanoparticles. International journal of molecular sciences. vol 24. issue 1. 2023-01-08. PMID:36613801. abnormally phosphorylated tau protein is the principal component of neurofibrillary tangles, accumulating in the brain in many neurodegenerative diseases, including alzheimer's disease. 2023-01-08 2023-08-14 human
Young-Kook Kim, Yoon Seok Jung, Juhyun Son. Transcriptome Profile in the Mouse Brain of Hepatic Encephalopathy and Alzheimer's Disease. International journal of molecular sciences. vol 24. issue 1. 2023-01-08. PMID:36614117. alzheimer's disease (ad), the most common neurodegenerative disease, is characterized by tau hyperphosphorylation, excessive amyloid beta (aβ) accumulation, the formation of fibrillary tangles, hippocampus atrophy, and neuroinflammation. 2023-01-08 2023-08-14 mouse
Daniel Kirsch, Arsal Shah, Erin Dixon, Hunter Kelley, Jonathan D Cherry, Weiming Xia, Sarah Daley, Nurgul Aytan, Kerry Cormier, Carol Kubilus, Rebecca Mathias, Victor E Alvarez, Bertrand R Huber, Ann C McKee, Thor D Stei. Vascular injury is associated with repetitive head impacts and tau pathology in chronic traumatic encephalopathy. Journal of neuropathology and experimental neurology. 2023-01-08. PMID:36617181. chronic traumatic encephalopathy (cte) is a neurodegenerative disease linked to repetitive head impacts (rhi) and characterized by perivascular hyperphosphorylated tau (p-tau) deposits. 2023-01-08 2023-08-14 human
Jiyoen Kim, Maria de Haro, Ismael Al-Ramahi, Lorena Laura Garaicoechea, Hyun-Hwan Jeong, Jun Young Sonn, Bakhos Tadros, Zhandong Liu, Juan Botas, Huda Yahya Zoghb. Evolutionarily conserved regulators of tau identify targets for new therapies. Neuron. 2023-01-07. PMID:36610398. tauopathies are neurodegenerative diseases that involve the pathological accumulation of tau proteins; in this family are alzheimer disease, corticobasal degeneration, and chronic traumatic encephalopathy, among others. 2023-01-07 2023-08-14 mouse
b' \\xc5\\x9eenay G\\xc3\\xb6r\\xc3\\xbcc\\xc3\\xbc Y\\xc4\\xb1lmaz, Salam Almasri, Yasemin Yuyucu Karabulut, Murat Korkmaz, \\xc3\\x96znur Bucak, Sibel O\\xc4\\x9fuzkan Balc\\xc4\\xb. Okadaic Acid-Induced Alzheimer\'s in Rat Brain: Phytochemical Cucurbitacin E Contributes to Memory Gain by Reducing TAU Protein Accumulation. Omics : a journal of integrative biology. 2023-01-03. PMID:36594931.' alzheimer's disease (ad) is a neurodegenerative disease characterized by progressive memory loss and cognitive decline, with hallmark pathologies related to amyloid beta (aβ) and tau. 2023-01-03 2023-08-14 rat
Shannon Faris, Weihua Jin, James Gibson, Anqesha Murray, Nathan Smith, Peng He, Fuming Zhang, Robert Linhardt, Chunyu Wan. Small-molecule compound from AlphaScreen disrupts tau-glycan interface. Frontiers in molecular biosciences. vol 9. 2023-01-02. PMID:36589242. tauopathies are neurodegenerative diseases characterized by intracellular abnormal tau deposits in the brain. 2023-01-02 2023-08-14 Not clear
Louise Bryan, Saurabh Awasthi, Yuanjie Li, Peter Niraj Nirmalraj, Sandor Balog, Jerry Yang, Michael Maye. Site-Specific C-Terminal Fluorescent Labeling of Tau Protein. ACS omega. vol 7. issue 50. 2022-12-26. PMID:36570287. formation of tau protein aggregates in neurons is a pathological hallmark of several neurodegenerative diseases, including alzheimer's disease. 2022-12-26 2023-08-14 Not clear
Fernando Gonzalez-Ortiz, Michael Turton, Przemysław R Kac, Denis Smirnov, Enrico Premi, Roberta Ghidoni, Luisa Benussi, Valentina Cantoni, Claudia Saraceno, Jasmine Rivolta, Nicholas J Ashton, Barbara Borroni, Douglas Galasko, Peter Harrison, Henrik Zetterberg, Kaj Blennow, Thomas K Karikar. Brain-derived tau: a novel blood-based biomarker for Alzheimer's disease-type neurodegeneration. Brain : a journal of neurology. 2022-12-26. PMID:36572122. furthermore, plasma brain-derived tau accurately distinguished autopsy-confirmed alzheimer's disease from other neurodegenerative diseases (area under the curve = 86.4%) while neurofilament light did not (area under the curve = 54.3%). 2022-12-26 2023-08-14 human
Fernando Gonzalez-Ortiz, Michael Turton, Przemysław R Kac, Denis Smirnov, Enrico Premi, Roberta Ghidoni, Luisa Benussi, Valentina Cantoni, Claudia Saraceno, Jasmine Rivolta, Nicholas J Ashton, Barbara Borroni, Douglas Galasko, Peter Harrison, Henrik Zetterberg, Kaj Blennow, Thomas K Karikar. Brain-derived tau: a novel blood-based biomarker for Alzheimer's disease-type neurodegeneration. Brain : a journal of neurology. 2022-12-26. PMID:36572122. notably, plasma/serum brain-derived tau correlated with neurofilament light only in alzheimer's disease but not in the other neurodegenerative diseases. 2022-12-26 2023-08-14 human
Yanan Zhu, Lauren Gandy, Fuming Zhang, Jian Liu, Chunyu Wang, Laura J Blair, Robert J Linhardt, Lianchun Wan. Heparan Sulfate Proteoglycans in Tauopathy. Biomolecules. vol 12. issue 12. 2022-12-23. PMID:36551220. tauopathies are a class of neurodegenerative diseases, including alzheimer's disease, and are characterized by intraneuronal tau inclusion in the brain and the patient's cognitive decline with obscure pathogenesis. 2022-12-23 2023-08-14 Not clear