| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lijun Zhou, Meng Xie, Xinxin Wang, Renshi X. The usage and advantages of several common amyotrophic lateral sclerosis animal models. Frontiers in neuroscience. vol 18. 2024-04-10. PMID:38595972. |
amyotrophic lateral sclerosis is a fatal, multigenic, multifactorial neurodegenerative disease characterized by upper and lower motor neuron loss. |
2024-04-10 |
2024-04-12 |
mouse |
| Nasser AlMadan, Ali AlMajed, Mohammed AlAbbad, Fadhel AlNashmi, Abdulmohsen Aleiss. Dental Management of Patients With Amyotrophic Lateral Sclerosis. Cureus. vol 15. issue 12. 2024-01-16. PMID:38226086. |
amyotrophic lateral sclerosis (als) is a neurodegenerative disease that affects the upper and lower motor neurons with upper and lower motor neuron manifestations. |
2024-01-16 |
2024-01-18 |
Not clear |
| Mary-Louise Rogers, David W Schultz, Vassilios Karnaros, Stephanie R Shephear. Urinary biomarkers for amyotrophic lateral sclerosis: candidates, opportunities and considerations. Brain communications. vol 5. issue 6. 2023-11-10. PMID:37946793. |
amyotrophic lateral sclerosis is a relentless neurodegenerative disease that is mostly fatal within 3-5 years and is diagnosed on evidence of progressive upper and lower motor neuron degeneration. |
2023-11-10 |
2023-11-20 |
Not clear |
| Xin Xiao, Min Li, Zhi Ye, Xiaoyan He, Jun Wei, Yunhong Zh. Amyotrophic lateral sclerosis & frontotemporal degeneration. 2023-11-05. PMID:37926865. |
amyotrophic lateral sclerosis (als) is a fatal neurodegenerative disease associated with upper and lower motor neuron degeneration and necrosis, characterized by progressive muscle weakness, atrophy, and paralysis. |
2023-11-05 |
2023-11-08 |
Not clear |
| Pranvera Hoxhaj, Natasha Hastings, Meet Popatbhai Kachhadia, Riya Gupta, Udeept Sindhu, Shreya A Durve, Areeba Azam, María J Auz Vinueza, Bhuvan, Shwe H Win, Deepak C Rathod, Aiman P Afsa. Exploring Advancements in the Treatment of Amyotrophic Lateral Sclerosis: A Comprehensive Review of Current Modalities and Future Prospects. Cureus. vol 15. issue 9. 2023-10-24. PMID:37868386. |
a combination of both upper and lower motor neuron degeneration ultimately leads to respiratory failure, similar to other dementia-type neurodegenerative diseases. |
2023-10-24 |
2023-11-08 |
Not clear |
| Soledad Marton, Ernesto Miquel, Joaquín Acosta-Rodríguez, Santiago Fontenla, Gabriela Libisch, Patricia Cassin. SOD1 ASN neuro. vol 15. 2023-08-30. PMID:37644868. |
sod1 amyotrophic lateral sclerosis (als) is a fatal neurodegenerative disease characterized by upper and lower motor neuron (mn) degeneration. |
2023-08-30 |
2023-09-07 |
Not clear |
| Venkateswaran Rajagopalan, Krishna G Chaitanya, Erik P Pior. Quantitative Brain MRI Metrics Distinguish Four Different ALS Phenotypes: A Machine Learning Based Study. Diagnostics (Basel, Switzerland). vol 13. issue 9. 2023-05-14. PMID:37174914. |
amyotrophic lateral sclerosis (als) is a fatal neurodegenerative disease whose diagnosis depends on the presence of combined lower motor neuron (lmn) and upper motor neuron (umn) degeneration. |
2023-05-14 |
2023-08-14 |
Not clear |
| Kelly A Rich, Megan G Pino, Mehmet E Yalvac, Ashley Fox, Hallie Harris, Maria H H Balch, W David Arnold, Stephen J Kol. Impaired motor unit recovery and maintenance in a knock-in mouse model of ALS-associated Kif5a variant. Neurobiology of disease. 2023-05-10. PMID:37164288. |
contrastingly, gain of function splice-site variants in the c-terminal, cargo-binding domain of kif5a are associated with amyotrophic lateral sclerosis (als), a neurodegenerative disease involving death of upper and lower motor neurons, ultimately leading to degradation of the motor unit (mu; an alpha motor neuron and all the myofibers it innervates) and death. |
2023-05-10 |
2023-08-14 |
mouse |
| André D J Mckenzie, Taylor R Garrett, Eryn L Werry, Michael Kassio. Purinergic P2X ACS chemical neuroscience. 2022-05-05. PMID:35512313. |
purinergic p2x amyotrophic lateral sclerosis (als) is a progressive neurodegenerative disease characterized by upper and lower motor neuron loss. |
2022-05-05 |
2023-08-13 |
Not clear |
| Ting-Jung Lin, Guang-Chao Cheng, Luo-Yun Wu, Wei-Yu Lai, Thai-Yen Ling, Yung-Che Kuo, Yen-Hua Huan. Potential of Cellular Therapy for ALS: Current Strategies and Future Prospects. Frontiers in cell and developmental biology. vol 10. 2022-04-04. PMID:35372346. |
amyotrophic lateral sclerosis (als) is a fatal neurodegenerative disease characterized by progressive upper and lower motor neuron (mn) degeneration with unclear pathology. |
2022-04-04 |
2023-08-13 |
Not clear |
| Reilly L Allison, Jacob W Adelman, Jenica Abrudan, Raul A Urrutia, Michael T Zimmermann, Angela J Mathison, Allison D Eber. Microglia Influence Neurofilament Deposition in ALS iPSC-Derived Motor Neurons. Genes. vol 13. issue 2. 2022-02-25. PMID:35205286. |
amyotrophic lateral sclerosis (als) is a fatal neurodegenerative disease in which upper and lower motor neuron loss is the primary phenotype, leading to muscle weakness and wasting, respiratory failure, and death. |
2022-02-25 |
2023-08-13 |
Not clear |
| Tiziana Bonifacino, Roberta Arianna Zerbo, Matilde Balbi, Carola Torazza, Giulia Frumento, Ernesto Fedele, Giambattista Bonanno, Marco Milanes. Nearly 30 Years of Animal Models to Study Amyotrophic Lateral Sclerosis: A Historical Overview and Future Perspectives. International journal of molecular sciences. vol 22. issue 22. 2021-11-30. PMID:34830115. |
amyotrophic lateral sclerosis (als) is a fatal, multigenic, multifactorial, and non-cell autonomous neurodegenerative disease characterized by upper and lower motor neuron loss. |
2021-11-30 |
2023-08-13 |
mouse |
| Paulo Victor Sgobbi de Souza, Wladimir Bocca Vieira de Rezende Pinto, Igor Braga Farias, Bruno de Mattos Lombardi Badia, Icaro França Navarro Pinto, Gustavo Carvalho Costa, Carolina Maria Marin, Ana Carolina Dos Santos Jorge, Emília Correia Souto, Paulo de Lima Serrano, Roberta Ismael Lacerda Machado, Marco Antônio Troccoli Chieia, Enrico Bertini, Acary Souza Bulle Oliveir. Progressive spastic tetraplegia and axial hypotonia (STAHP) due to SOD1 deficiency: is it really a new entity? Orphanet journal of rare diseases. vol 16. issue 1. 2021-10-06. PMID:34380534. |
amyotrophic lateral sclerosis (als) is a rare, progressive, and fatal neurodegenerative disease due to upper and lower motor neuron involvement with symptoms classically occurring in adulthood with an increasing recognition of juvenile presentations and childhood neurodegenerative disorders caused by genetic variants in genes related to amyotrophic lateral sclerosis. |
2021-10-06 |
2023-08-13 |
Not clear |
| Ilaria Giovannelli, Nadhim Bayatti, Abigail Brown, Dennis Wang, Marius Mickunas, William Camu, Jean-Luc Veyrune, Christine Payan, Cecilia Garlanda, Massimo Locati, Raul Juntas-Morales, Nicolas Pageot, Andrea Malaspina, Ulf Andreasson, Carey Suehs, Safa Saker, Christophe Masseguin, John de Vos, Henrik Zetterberg, Ammar Al-Chalabi, P Nigel Leigh, Timothy Tree, Gilbert Bensimon, Paul R Heath, Pamela J Shaw, Janine Kirb. Amyotrophic lateral sclerosis transcriptomics reveals immunological effects of low-dose interleukin-2. Brain communications. vol 3. issue 3. 2021-08-20. PMID:34409288. |
amyotrophic lateral sclerosis is a fatal neurodegenerative disease causing upper and lower motor neuron loss and currently no effective disease-modifying treatment is available. |
2021-08-20 |
2023-08-13 |
human |
| J Saul, E Hutchins, R Reiman, M Saul, L W Ostrow, B T Harris, K Van Keuren-Jensen, R Bowser, N Bakka. Global alterations to the choroid plexus blood-CSF barrier in amyotrophic lateral sclerosis. Acta neuropathologica communications. vol 8. issue 1. 2021-05-31. PMID:32586411. |
amyotrophic lateral sclerosis (als) is a neurodegenerative disease associated with both upper and lower motor neuron loss, as well as altered proteomic and metabolomic signatures in the csf. |
2021-05-31 |
2023-08-13 |
human |
| Christine Marques, Thibaut Burg, Jelena Scekic-Zahirovic, Mathieu Fischer, Caroline Rouau. Upper and Lower Motor Neuron Degenerations Are Somatotopically Related and Temporally Ordered in the Brain sciences. vol 11. issue 3. 2021-04-13. PMID:33805792. |
upper and lower motor neuron degenerations are somatotopically related and temporally ordered in the amyotrophic lateral sclerosis (als) is a devastating and fatal neurodegenerative disease arising from the combined degeneration of upper motor neurons (umn) in the motor cortex, and lower motor neurons (lmn) in the brainstem and spinal cord. |
2021-04-13 |
2023-08-13 |
Not clear |
| Melania Filareti, Silvia Luotti, Laura Pasetto, Mauro Pignataro, Katia Paolella, Paolo Messina, Elisabetta Pupillo, Massimiliano Filosto, Christian Lunetta, Jessica Mandrioli, Giuseppe Fuda, Andrea Calvo, Adriano Chiò, Massimo Corbo, Caterina Bendotti, Ettore Beghi, Valentina Bonett. Decreased Levels of Foldase and Chaperone Proteins Are Associated with an Early-Onset Amyotrophic Lateral Sclerosis. Frontiers in molecular neuroscience. vol 10. 2020-10-01. PMID:28428745. |
amyotrophic lateral sclerosis (als) is a fatal neurodegenerative disease characterized by a progressive upper and lower motor neuron degeneration. |
2020-10-01 |
2023-08-13 |
Not clear |
| Raffaella Adami, Daniele Botta. Spinal Muscular Atrophy Modeling and Treatment Advances by Induced Pluripotent Stem Cells Studies. Stem cell reviews and reports. vol 15. issue 6. 2020-08-04. PMID:31863335. |
spinal muscular atrophy (sma) is a neurodegenerative disease characterized by specific and predominantly lower motor neuron (mn) loss. |
2020-08-04 |
2023-08-13 |
mouse |
| Ali Amin Lari, Amer A Ghavanini, Hamid Reza Bokae. A review of electrophysiological studies of lower motor neuron involvement in amyotrophic lateral sclerosis. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. vol 40. issue 6. 2019-12-02. PMID:30877611. |
amyotrophic lateral sclerosis (als) is a neurodegenerative disease involving both the upper and lower motor neuron diseases. |
2019-12-02 |
2023-08-13 |
Not clear |
| S Brah, K Assogba, E Adehossi, S Kevi, K Apetse, D Kombate, B Barque, A K Ballougou, E K Grunitzk. [Amyotrophic Lateral Sclerosis (ALS) in the 10 last years in CHU Campus of Lomé (TOGO)]. Le Mali medical. vol 29. issue 2. 2019-11-20. PMID:30049125. |
amyotrophic lateral sclerosis (als) is a neurodegenerative disease that causes damage of upper motor neuron and lower motor neuron. |
2019-11-20 |
2023-08-13 |
Not clear |