All Relations between Neurodegenerative Diseases and cerebellum

Publication Sentence Publish Date Extraction Date Species
Jessica A Bernar. Cerebello-Hippocampal Interactions in the Human Brain: A New Pathway for Insights Into Aging. Cerebellum (London, England). 2024-03-04. PMID:38438826. given the role of both regions in cognition and aging, and emerging evidence indicating that the cerebellum is impacted in age-related neurodegenerative disease such as alzheimer's, i propose that further attention to this circuit is warranted. 2024-03-04 2024-03-07 human
David Bendetowicz, Margherita Fabbri, Federico Sirna, Pierre-Olivier Fernagut, Alexandra Foubert-Samier, Tiphaine Saulnier, Anne Pavy Le Traon, Cécile Proust-Lima, Olivier Rascol, Wassilios G Meissne. Recent Advances in Clinical Trials in Multiple System Atrophy. Current neurology and neuroscience reports. 2024-02-28. PMID:38416311. this review summarizes previous and ongoing neuroprotection trials in multiple system atrophy (msa), a rare and fatal neurodegenerative disease characterized by parkinsonism, cerebellar, and autonomic dysfunction. 2024-02-28 2024-03-01 Not clear
Shani Blumenreich, Doreen Padan Ben-Yashar, Tali Shalit, Meital Kupervaser, Ivan Milenkovic, Tammar Joseph, Anthony H Futerma. Proteomics analysis of the brain from a Gaucher disease mouse identifies pathological pathways including a possible role for transglutaminase 1. Journal of neurochemistry. 2023-12-10. PMID:38071490. one protein, transglutaminase 1 (tgm1), which is elevated in a number of neurodegenerative diseases, was absent from the control group but was found at high levels in cbe-injected mice, and located in the extracellular matrix (ecm) in layer v of the cortex and intracellularly in purkinje cells in the cerebellum. 2023-12-10 2023-12-17 mouse
Tomohiko Imai, Kenichi Sakamoto, Tatsuji Hasegawa, Yoko Shioda, Yoshiyuki Tsutsumi, Satoshi Sakaue, Toshihiko Imamura, Akira Morimoto, Tomoko Iehar. Cerebellar peduncle damage in Langerhans cell histiocytosis-associated neurodegenerative disease revealed by diffusion tensor imaging. Neuroradiology. 2023-11-20. PMID:37983002. cerebellar peduncle damage in langerhans cell histiocytosis-associated neurodegenerative disease revealed by diffusion tensor imaging. 2023-11-20 2023-11-29 Not clear
R G Harrell, A R Cassidy, B N Klatt, P Hovareshti, S L Whitne. Vestibular rehabilitation in cerebellar ataxia with neuropathy and vestibular areflexia syndrome (CANVAS)- A case report. Journal of otology. vol 18. issue 4. 2023-10-26. PMID:37877066. cerebellar ataxia, neuropathy, and vestibular areflexia syndrome (canvas) is a neurodegenerative disease of the cerebellum. 2023-10-26 2023-11-08 Not clear
Chao Li, Han Zhang, Kexin Tong, Menghua Cai, Fei Gao, Jia Yang, Yi Xu, Huaishan Wang, Hui Chen, Yu Hu, Wei He, Jianmin Zhan. Genetic Deletion of Thorase Causes Purkinje Cell Loss and Impaired Motor Coordination Behavior. Cells. vol 12. issue 16. 2023-08-26. PMID:37626842. our findings provide a better understanding of the role of thorase in the cerebellum, which is a theoretical basis for thorase as a therapeutic drug target for neurodegenerative diseases. 2023-08-26 2023-09-07 mouse
Abdoul Rachid, Bo Chen, Guangwen Zh. A preliminary study on the effect of renal function on the metabolism of Quantitative imaging in medicine and surgery. vol 13. issue 8. 2023-08-15. PMID:37581043. a preliminary study on the effect of renal function on the metabolism of the cerebellum is less affected by normal aging or neurodegenerative diseases, the aim of this paper is to investigate the effect of renal function status on uptake of 2-deoxy-2-[ 2023-08-15 2023-09-07 Not clear
Sara Bernardi, Federica Gemignani, Maria Marches. The involvement of Purkinje cells in progressive myoclonic epilepsy: Focus on neuronal ceroid lipofuscinosis. Neurobiology of disease. 2023-08-13. PMID:37573956. the progressive myoclonic epilepsies (pmes) are a group of rare neurodegenerative diseases characterized by myoclonus, epileptic seizures, and progressive neurological deterioration with cerebellar involvement. 2023-08-13 2023-08-16 Not clear
Martina Sucha, Simona Benediktova, Filip Tichanek, Jan Jedlicka, Stepan Kapl, Dana Jelinkova, Zdenka Purkartova, Jan Tuma, Jitka Kuncova, Jan Cendeli. Experimental Treatment with Edaravone in a Mouse Model of Spinocerebellar Ataxia 1. International journal of molecular sciences. vol 24. issue 13. 2023-07-14. PMID:37445867. nevertheless, edaravone has not been tested yet in the context of spinocerebellar ataxia 1 (sca1), an incurable neurodegenerative disease characterized mainly by cerebellar disorder, with a strong contribution of inflammation and mitochondrial dysfunction. 2023-07-14 2023-08-14 mouse
Naoum P Issa, Serdar Aydin, Shail Bhatnagar, Nicholas W Baumgartner, Jacquelyn Hill, Sravya Aluri, Chloe S Valentic, Eric Polley, Christopher M Gomez, Kourosh Rezani. Intermuscular Coherence in Spinocerebellar Ataxias 3 and 6: a Preliminary Study. Cerebellum (London, England). 2023-07-10. PMID:37428409. spinocerebellar ataxias (scas) are familial neurodegenerative diseases involving the cerebellum and spinocerebellar tracts. 2023-07-10 2023-08-14 human
Libera Siciliano, Giusy Olivito, Nicole Urbini, Maria Caterina Silveri, Maria Leggi. The rising role of cognitive reserve and associated compensatory brain networks in spinocerebellar ataxia type 2. Journal of neurology. 2023-07-08. PMID:37421466. the present study assessed cr and its impact on cognitive abilities in spinocerebellar ataxia type 2 (sca2), which is a rare cerebellar neurodegenerative disease. 2023-07-08 2023-08-14 Not clear
Sofia Toniolo, Iolanda Pisotta, Mario Mant. Editorial: The role of the cerebellum in dementia and neurodegenerative diseases. Frontiers in neuroscience. vol 17. 2023-07-03. PMID:37397444. editorial: the role of the cerebellum in dementia and neurodegenerative diseases. 2023-07-03 2023-08-14 Not clear
Kimberley Stee, Mario Van Poucke, Mark Lowrie, Luc Van Ham, Luc Peelman, Natasha Olby, Sofie F M Bhatt. Phenotypic and genetic aspects of hereditary ataxia in dogs. Journal of veterinary internal medicine. 2023-06-21. PMID:37341581. hereditary ataxias are a large group of neurodegenerative diseases that have cerebellar or spinocerebellar dysfunction as core feature, occurring as an isolated sign or as part of a syndrome. 2023-06-21 2023-08-14 Not clear
Shailendra Mohan Tripathi, Naif Ali Majrashi, Ali S Alyami, Wael A Ageeli, Turkey A Refae. A Systematic Review of PET Contrasted with MRI for Detecting Crossed Cerebellar Diaschisis in Patients with Neurodegenerative Diseases. Diagnostics (Basel, Switzerland). vol 13. issue 10. 2023-05-27. PMID:37238158. a systematic review of pet contrasted with mri for detecting crossed cerebellar diaschisis in patients with neurodegenerative diseases. 2023-05-27 2023-08-14 human
Shailendra Mohan Tripathi, Naif Ali Majrashi, Ali S Alyami, Wael A Ageeli, Turkey A Refae. A Systematic Review of PET Contrasted with MRI for Detecting Crossed Cerebellar Diaschisis in Patients with Neurodegenerative Diseases. Diagnostics (Basel, Switzerland). vol 13. issue 10. 2023-05-27. PMID:37238158. this study concludes that pet is a common, accurate, and sensitive technique for detecting both crossed cerebellar and uncrossed basal ganglia as well as thalamic diaschisis in neurodegenerative diseases, while mri is better for measuring brain volume. 2023-05-27 2023-08-14 human
Jessica Tiberi, Marco Segatto, Maria Teresa Fiorenza, Piergiorgio La Ros. Apparent Opportunities and Hidden Pitfalls: The Conflicting Results of Restoring NRF2-Regulated Redox Metabolism in Friedreich's Ataxia Pre-Clinical Models and Clinical Trials. Biomedicines. vol 11. issue 5. 2023-05-27. PMID:37238963. friedreich's ataxia (frda) is an autosomal, recessive, inherited neurodegenerative disease caused by the loss of activity of the mitochondrial protein frataxin (fxn), which primarily affects dorsal root ganglia, cerebellum, and spinal cord neurons. 2023-05-27 2023-08-14 Not clear
Karamazovova Simona, Matuskova Veronika, Ismail Zahinoor, Vyhnalek Marti. Neuropsychiatric symptoms in spinocerebellar ataxias and Friedreich ataxia. Neuroscience and biobehavioral reviews. 2023-05-03. PMID:37137435. spinocerebellar ataxias (sca) and friedreich ataxia (frda) are rare neurodegenerative diseases of the cerebellum presenting mainly with a progressive loss of gait and limb coordination, dysarthria, and other motor disturbances, but also a range of cognitive and neuropsychiatric symptoms. 2023-05-03 2023-08-14 Not clear
Sibtain Ahmed, Ayra Siddiqui, Ralph J DeBerardinis, Min Ni, Wen Gu Lai, Feng Cai, Hieu S Vu, Bushra Afroz. L-2-hydroxyglutaric aciduria - review of literature and case series. Annals of medicine and surgery (2012). vol 85. issue 4. 2023-04-28. PMID:37113859. l-2-hydroxyglutaric aciduria (l2hga) is an autosomal recessive, slowly progressive neurodegenerative disease characterized by psychomotor delay and cerebellar dysfunction. 2023-04-28 2023-08-14 Not clear
b' Cak Ciss\\xc3\\xa9, L Ciss\\xc3\\xa9, O Samass\\xc3\\xa9kou, H O Ba, T Coulibaly, S H Diallo, S Diallo, A Tam\\xc3\\xa9ga, S Diarra, A B Ma\\xc3\\xafga, F Kan\\xc3\\xa9, A Yalcouy\\xc3\\xa9, A Bocoum, M E Demb\\xc3\\xa9l\\xc3\\xa9, O Traor\\xc3\\xa9, A Simaga, S F Traor\\xc3\\xa9, M Keita, K Fischbeck, M Traor\\xc3\\xa9, C O Guinto, G Landour\\xc3\\xa. Clinical, paraclinical and genetic aspects of autosomal recessive cerebellar ataxias (ARCA) in Mali. Le Mali medical. vol 37. issue 4. 2023-03-15. PMID:36919030.' autosomal recessive cerebellar ataxias (arca) are a group of rare and heterogynous neurodegenerative diseases mainly characterized by unbalance and walking difficulty and movement incoordination. 2023-03-15 2023-08-14 Not clear
Miryam Carecchio, Michele Mainardi, Giulia Bonat. The clinical and genetic spectrum of primary familial brain calcification. Journal of neurology. 2023-03-02. PMID:36862146. primary familial brain calcification (pfbc), formerly known as fahr's disease, is a rare neurodegenerative disease characterized by bilateral progressive calcification of the microvessels of the basal ganglia and other cerebral and cerebellar structures. 2023-03-02 2023-08-14 human