All Relations between Neurodegenerative Diseases and cerebellum

Publication Sentence Publish Date Extraction Date Species
Arnulf H Koeppe. The neuropathology of the adult cerebellum. Handbook of clinical neurology. vol 154. 2018-09-28. PMID:29903436. the cerebellum is a prominent target of several sporadic and hereditary neurodegenerative diseases, including multiple system atrophy, spinocerebellar ataxia, and friedreich ataxia. 2018-09-28 2023-08-13 Not clear
G Olivito, M Lupo, C Iacobacci, S Clausi, S Romano, M Masciullo, M Molinari, M Cercignani, M Bozzali, M Leggi. Structural cerebellar correlates of cognitive functions in spinocerebellar ataxia type 2. Journal of neurology. vol 265. issue 3. 2018-08-23. PMID:29356974. spinocerebellar ataxia type 2 (sca2) is an autosomal dominant neurodegenerative disease involving the cerebellum and characterized by a typical motor syndrome. 2018-08-23 2023-08-13 Not clear
Jeanne Hsieh, Jen-Wei Liu, Horng-Jyh Harn, Kuo-Wei Hsueh, Karthyayani Rajamani, Yu-Chen Deng, Chih-Min Chia, Woei-Cheang Shyu, Shinn-Zong Lin, Tzyy-Wen Chio. Human Olfactory Ensheathing Cell Transplantation Improves Motor Function in a Mouse Model of Type 3 Spinocerebellar Ataxia. Cell transplantation. vol 26. issue 10. 2018-07-19. PMID:29251109. spinocerebellar ataxia (sca) is a progressive neurodegenerative disease that affects the cerebellum and spinal cord. 2018-07-19 2023-08-13 mouse
E Y Scott, K D Woolard, C J Finno, M C T Penedo, J D Murra. Variation in MUTYH expression in Arabian horses with Cerebellar Abiotrophy. Brain research. vol 1678. 2018-07-16. PMID:29103988. cerebellar abiotrophy (ca) is a neurodegenerative disease in arabian horses affecting the cerebellum, more specifically the purkinje neurons. 2018-07-16 2023-08-13 Not clear
G Olivito, M Lupo, C Iacobacci, S Clausi, S Romano, M Masciullo, M Molinari, M Cercignani, M Bozzali, M Leggi. Microstructural MRI Basis of the Cognitive Functions in Patients with Spinocerebellar Ataxia Type 2. Neuroscience. vol 366. 2018-06-29. PMID:29031602. spinocerebellar ataxia type 2 (sca2) is an autosomal dominant neurodegenerative disease involving the cerebellum. 2018-06-29 2023-08-13 Not clear
Junping Xu, Chengliang Hu, Shuangxi Chen, Huifan Shen, Qiong Jiang, Peizhi Huang, Weijiang Zha. Neuregulin-1 protects mouse cerebellum against oxidative stress and neuroinflammation. Brain research. vol 1670. 2018-04-26. PMID:28623147. cerebellum undergoes degenerative changes in neurodegenerative diseases. 2018-04-26 2023-08-13 mouse
Lucía Rivas, Óscar Blanco, Cristina Torreira, Alfredo Repáraz, Cristina Melcón, Alfonso Amad. [Pontocerebellar hypoplasia secondary to CASK gene deletion: Case report]. Revista chilena de pediatria. vol 88. issue 4. 2018-04-23. PMID:28898323. pontocerebellar hypoplasia (pch) is a reduction of the size of the cerebellum and pons secondary to an alteration in its development, and can be caused by neurodegenerative diseases of genetic origin, of which there are known 10 subtypes (pch 1-10), cortical malformations, metabolic and genetic diseases. 2018-04-23 2023-08-13 Not clear
Wenhui Qu, Andrea Johnson, Joo Hyun Kim, Abigail Lukowicz, Daniel Svedberg, Marija Cvetanovi. Inhibition of colony-stimulating factor 1 receptor early in disease ameliorates motor deficits in SCA1 mice. Journal of neuroinflammation. vol 14. issue 1. 2018-03-26. PMID:28545543. polyglutamine (polyq) expansion in the protein ataxin-1 (atxn1) causes spinocerebellar ataxia type 1 (sca1), a fatal dominantly inherited neurodegenerative disease characterized by motor deficits, cerebellar neurodegeneration, and gliosis. 2018-03-26 2023-08-13 mouse
Georg Auburger, Nesli-Ece Sen, David Meierhofer, Ayşe-Nazlı Başak, Aaron D Gitle. Efficient Prevention of Neurodegenerative Diseases by Depletion of Starvation Response Factor Ataxin-2. Trends in neurosciences. vol 40. issue 8. 2018-02-26. PMID:28684172. these physiological actions were now revealed to be crucial for human neurodegenerative diseases, given that atxn2 depletion is surprisingly efficient in preventing motor neuron and cerebellar atrophy, as demonstrated in mouse models, flies, and yeast. 2018-02-26 2023-08-13 mouse
Michael Lattke, Stephanie N Reichel, Alexander Magnutzki, Alireza Abaei, Volker Rasche, Paul Walther, Dinis P Calado, Boris Ferger, Thomas Wirth, Bernd Bauman. Transient IKK2 activation in astrocytes initiates selective non-cell-autonomous neurodegeneration. Molecular neurodegeneration. vol 12. issue 1. 2018-02-22. PMID:28193238. inflammatory cerebellar ataxias are neurodegenerative diseases occurring in various autoimmune/inflammatory conditions, e.g. 2018-02-22 2023-08-13 Not clear
Austin Ferro, Emily Carbone, Evan Marzouk, Asher Siegel, Donna Nguyen, Kailen Polley, Jessilyn Hartman, Kimberley Frederick, Stephen Ives, Sarita Lagalwa. Treating SCA1 Mice with Water-Soluble Compounds to Non-Specifically Boost Mitochondrial Function. Journal of visualized experiments : JoVE. issue 119. 2018-01-29. PMID:28190022. mitochondrial dysfunction plays a significant role in the aging process and in neurodegenerative diseases including several hereditary spinocerebellar ataxias and other movement disorders marked by progressive degeneration of the cerebellum. 2018-01-29 2023-08-13 mouse
Austin Ferro, Emily Carbone, Evan Marzouk, Asher Siegel, Donna Nguyen, Kailen Polley, Jessilyn Hartman, Kimberley Frederick, Stephen Ives, Sarita Lagalwa. Treating SCA1 Mice with Water-Soluble Compounds to Non-Specifically Boost Mitochondrial Function. Journal of visualized experiments : JoVE. issue 119. 2018-01-29. PMID:28190022. these methods are robust techniques for determining mitochondrial dysfunction and the efficacy of treatment with water-soluble compounds in cerebellar neurodegenerative disease. 2018-01-29 2023-08-13 mouse
Austin Ferro, Emily Carbone, Jenny Zhang, Evan Marzouk, Monica Villegas, Asher Siegel, Donna Nguyen, Thomas Possidente, Jessilyn Hartman, Kailen Polley, Melissa A Ingram, Georgia Berry, Thomas H Reynolds, Bernard Possidente, Kimberley Frederick, Stephen Ives, Sarita Lagalwa. Short-term succinic acid treatment mitigates cerebellar mitochondrial OXPHOS dysfunction, neurodegeneration and ataxia in a Purkinje-specific spinocerebellar ataxia type 1 (SCA1) mouse model. PloS one. vol 12. issue 12. 2017-12-29. PMID:29211771. mitochondrial dysfunction plays a significant role in neurodegenerative disease including ataxias and other movement disorders, particularly those marked by progressive degeneration in the cerebellum. 2017-12-29 2023-08-13 mouse
Mariana Eiras Borges, Alessandra Mussi Ribeiro, José Rodrigo Pauli, Luciana Mendonça Arantes, Eliete Luciano, Leandro Pereira de Moura, José Alexandre Curiacos de Almeida Leme, Alessandra Medeiros, Natália Oliveira Bertolini, Clarice Yoshiko Sibuya, Ricardo José Gome. Cerebellar Insulin/IGF-1 signaling in diabetic rats: Effects of exercise training. Neuroscience letters. vol 639. 2017-12-19. PMID:28034783. the diabetes mellitus (dm) is a chronic disease associated with loss of brain regions such as the cerebellum, increasing the risk of developing neurodegenerative diseases such as parkinson's disease (pd). 2017-12-19 2023-08-13 rat
Yoshihito Ishida, Hideshi Kawakami, Hiroyuki Kitajima, Ayaka Nishiyama, Yoshiki Sasai, Haruhisa Inoue, Keiko Mugurum. Vulnerability of Purkinje Cells Generated from Spinocerebellar Ataxia Type 6 Patient-Derived iPSCs. Cell reports. vol 17. issue 6. 2017-11-20. PMID:27806289. spinocerebellar ataxia type 6 (sca6) is a dominantly inherited neurodegenerative disease characterized by loss of purkinje cells in the cerebellum. 2017-11-20 2023-08-13 Not clear
G Olivito, M Cercignani, M Lupo, C Iacobacci, S Clausi, S Romano, M Masciullo, M Molinari, M Bozzali, M Leggi. Neural substrates of motor and cognitive dysfunctions in SCA2 patients: A network based statistics analysis. NeuroImage. Clinical. vol 14. 2017-11-07. PMID:28393013. spinocerebellar ataxia type 2 (sca2) is an autosomal dominant neurodegenerative disease characterized by a progressive cerebellar syndrome, which can be isolated or associated with extracerebellar signs. 2017-11-07 2023-08-13 Not clear
Md Nabiul Islam, Yukio Takeshita, Akie Yanai, Amami Imagawa, Mir Rubayet Jahan, Greggory Wroblewski, Joe Nemoto, Ryutaro Fujinaga, Koh Shinod. Immunohistochemical analysis of huntingtin-associated protein 1 in adult rat spinal cord and its regional relationship with androgen receptor. Neuroscience. vol 340. 2017-11-06. PMID:27984179. in normal brains, it is abundantly expressed particularly in the limbic-hypothalamic regions that tend to be spared from neurodegeneration, whereas the areas with little hap1 expression, including the striatum, thalamus, cerebral neocortex and cerebellum, are targets in several neurodegenerative diseases. 2017-11-06 2023-08-13 rat
Christian Wächter, Lee E Eiden, Nedye Naumann, Candan Depboylu, Eberhard Weih. Loss of cerebellar neurons in the progression of lentiviral disease: effects of CNS-permeant antiretroviral therapy. Journal of neuroinflammation. vol 13. issue 1. 2017-10-05. PMID:27737697. the majority of investigations on hiv-associated neurocognitive disorders (hand) neglect the cerebellum in spite of emerging evidence for its role in higher cognitive functions and dysfunctions in common neurodegenerative diseases. 2017-10-05 2023-08-13 Not clear
E Y Scott, M C T Penedo, J D Murray, C J Finn. Defining Trends in Global Gene Expression in Arabian Horses with Cerebellar Abiotrophy. Cerebellum (London, England). vol 16. issue 2. 2017-09-22. PMID:27709457. equine cerebellar abiotrophy (ca) is a hereditary neurodegenerative disease that affects the purkinje neurons of the cerebellum and causes ataxia in arabian foals. 2017-09-22 2023-08-13 Not clear
Alberto Cacciola, Demetrio Milardi, Alessandro Calamuneri, Lilla Bonanno, Silvia Marino, Pietro Ciolli, Margherita Russo, Daniele Bruschetta, Antonio Duca, Fabio Trimarchi, Angelo Quartarone, Giuseppe Anastas. Constrained Spherical Deconvolution Tractography Reveals Cerebello-Mammillary Connections in Humans. Cerebellum (London, England). vol 16. issue 2. 2017-09-22. PMID:27774574. these pathways could improve our understanding of cerebellar role in several autonomic functions, visuospatial orientation, and memory and may shed new light on neurodegenerative diseases in which clinically relevant impairments in navigational skills or memory may become manifest at early stages. 2017-09-22 2023-08-13 human