| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alberto Cacciola, Demetrio Milardi, Alessandro Calamuneri, Lilla Bonanno, Silvia Marino, Pietro Ciolli, Margherita Russo, Daniele Bruschetta, Antonio Duca, Fabio Trimarchi, Angelo Quartarone, Giuseppe Anastas. Constrained Spherical Deconvolution Tractography Reveals Cerebello-Mammillary Connections in Humans. Cerebellum (London, England). vol 16. issue 2. 2017-09-22. PMID:27774574. |
these pathways could improve our understanding of cerebellar role in several autonomic functions, visuospatial orientation, and memory and may shed new light on neurodegenerative diseases in which clinically relevant impairments in navigational skills or memory may become manifest at early stages. |
2017-09-22 |
2023-08-13 |
human |
| Sriram Jayabal, Lovisa Ljungberg, Alanna J Wat. Transient cerebellar alterations during development prior to obvious motor phenotype in a mouse model of spinocerebellar ataxia type 6. The Journal of physiology. vol 595. issue 3. 2017-09-21. PMID:27531396. |
spinocerebellar ataxia type 6 (sca6) is a midlife-onset neurodegenerative disease caused by a cacna1a mutation; cacna1a is also implicated in cerebellar development. |
2017-09-21 |
2023-08-13 |
mouse |
| Joe Fenn, Mike Boursnell, Rebekkah J Hitti, Christopher A Jenkins, Rebecca L Terry, Simon L Priestnall, Patrick J Kenny, Cathryn S Mellersh, Oliver P Forma. Genome sequencing reveals a splice donor site mutation in the SNX14 gene associated with a novel cerebellar cortical degeneration in the Hungarian Vizsla dog breed. BMC genetics. vol 17. issue 1. 2017-09-13. PMID:27566131. |
cerebellar cortical degeneration (ccd) is an increasingly recognised neurodegenerative disease process affecting many dog breeds. |
2017-09-13 |
2023-08-13 |
dog |
| H Khonsari, M Schneider, S Al-Mahdawi, Y G Chianea, M Themis, C Parris, M A Pook, M Themi. Lentivirus-meditated frataxin gene delivery reverses genome instability in Friedreich ataxia patient and mouse model fibroblasts. Gene therapy. vol 23. issue 12. 2017-08-07. PMID:27518705. |
friedreich ataxia (frda) is a progressive neurodegenerative disease caused by deficiency of frataxin protein, with the primary sites of pathology being the large sensory neurons of the dorsal root ganglia and the cerebellum. |
2017-08-07 |
2023-08-13 |
mouse |
| Christine C Guo, Rachel Tan, John R Hodges, Xintao Hu, Saber Sami, Michael Hornberge. Network-selective vulnerability of the human cerebellum to Alzheimer's disease and frontotemporal dementia. Brain : a journal of neurology. vol 139. issue Pt 5. 2017-05-08. PMID:26912642. |
an intriguing yet untested possibility is that the cerebellar circuits, which share extensive connections with the cerebral cortex, could be selectively targeted by major neurodegenerative diseases. |
2017-05-08 |
2023-08-13 |
human |
| Christine C Guo, Rachel Tan, John R Hodges, Xintao Hu, Saber Sami, Michael Hornberge. Network-selective vulnerability of the human cerebellum to Alzheimer's disease and frontotemporal dementia. Brain : a journal of neurology. vol 139. issue Pt 5. 2017-05-08. PMID:26912642. |
here we examined the structural atrophy in the cerebellum across common types of neurodegenerative diseases, and characterized the functional connectivity patterns of these cerebellar atrophy regions. |
2017-05-08 |
2023-08-13 |
human |
| Christine C Guo, Rachel Tan, John R Hodges, Xintao Hu, Saber Sami, Michael Hornberge. Network-selective vulnerability of the human cerebellum to Alzheimer's disease and frontotemporal dementia. Brain : a journal of neurology. vol 139. issue Pt 5. 2017-05-08. PMID:26912642. |
these findings for the first time demonstrated the selective vulnerability of the cerebellum to common neurodegenerative disease, extending the network-based degeneration framework to the cerebellum. |
2017-05-08 |
2023-08-13 |
human |
| Julián Benito-León, Elan D Louis, Virginia Mato-Abad, Ulrike Dydak, Juan Álvarez-Linera, Juan Antonio Hernández-Tamames, José Antonio Molina-Arjona, Norberto Malpica, Michele Matarazzo, Juan Pablo Romero, Álvaro Sánchez-Ferr. In vivo neurometabolic profiling in orthostatic tremor. Medicine. vol 95. issue 37. 2017-02-10. PMID:27631243. |
reductions in both cerebral cortical and cerebellar naa suggest that there is neuronal damage or loss in ot, raising the intriguing question as to whether ot is a neurodegenerative disease. |
2017-02-10 |
2023-08-13 |
Not clear |
| Lipin Liang, Tao Chen, Yan W. The electrophysiology of spinocerebellar ataxias. Neurophysiologie clinique = Clinical neurophysiology. vol 46. issue 1. 2016-12-13. PMID:26947625. |
spinocerebellar ataxias (scas) are a group of autosomal dominantly inherited neurodegenerative diseases, involving the cerebellum and the brainstem. |
2016-12-13 |
2023-08-13 |
Not clear |
| Adele G Marthaler, Alisa Tubsuwan, Benjamin Schmid, Ulla B Poulsen, Poul Hyttel, Jørgen E Nielsen, Troels T Nielsen, Bjørn Hols. Generation of spinocerebellar ataxia type 2 patient-derived iPSC line H271. Stem cell research. vol 16. issue 1. 2016-12-13. PMID:27345803. |
spinocerebellar ataxia type 2 (sca2) is a neurodegenerative disease primarily affecting the cerebellum. |
2016-12-13 |
2023-08-13 |
Not clear |
| Adele G Marthaler, Benjamin Schmid, Alisa Tubsuwan, Ulla B Poulsen, Alexander F Engelbrecht, Ulrike A Mau-Holzmann, Poul Hyttel, Jørgen E Nielsen, Troels T Nielsen, Bjørn Hols. Generation of an isogenic, gene-corrected control cell line of the spinocerebellar ataxia type 2 patient-derived iPSC line H196. Stem cell research. vol 16. issue 1. 2016-12-13. PMID:27345804. |
spinocerebellar ataxia type 2 (sca2) is a neurodegenerative disease primarily affecting the cerebellum. |
2016-12-13 |
2023-08-13 |
Not clear |
| Adele G Marthaler, Benjamin Schmid, Alisa Tubsuwan, Ulla B Poulsen, Poul Hyttel, Troels T Nielsen, Jørgen E Nielsen, Bjørn Hols. Generation of spinocerebellar ataxia type 2 patient-derived iPSC line H266. Stem cell research. vol 16. issue 1. 2016-12-13. PMID:27345805. |
spinocerebellar ataxia type 2 (sca2) is a neurodegenerative disease primarily affecting the cerebellum. |
2016-12-13 |
2023-08-13 |
Not clear |
| Adele G Marthaler, Benjamin Schmid, Alisa Tubsuwan, Ulla B Poulsen, Alexander F Engelbrecht, Ulrike A Mau-Holzmann, Poul Hyttel, Jørgen E Nielsen, Troels T Nielsen, Bjørn Hols. Generation of an isogenic, gene-corrected control cell line of the spinocerebellar ataxia type 2 patient-derived iPSC line H271. Stem cell research. vol 16. issue 1. 2016-12-13. PMID:27345809. |
spinocerebellar ataxia type 2 (sca2) is a neurodegenerative disease primarily affecting the cerebellum. |
2016-12-13 |
2023-08-13 |
Not clear |
| Adele G Marthaler, Benjamin Schmid, Alisa Tubsuwan, Ulla B Poulsen, Poul Hyttel, Troels T Nielsen, Jørgen E Nielsen, Bjørn Hols. Generation of spinocerebellar ataxia type 2 patient-derived iPSC line H196. Stem cell research. vol 16. issue 1. 2016-12-13. PMID:27345814. |
spinocerebellar ataxia type 2 (sca2) is a neurodegenerative disease primarily affecting the cerebellum. |
2016-12-13 |
2023-08-13 |
Not clear |
| Adele G Marthaler, Alisa Tubsuwan, Benjamin Schmid, Ulla B Poulsen, Alexander F Engelbrecht, Ulrike A Mau-Holzmann, Poul Hyttel, Troels T Nielsen, Jørgen E Nielsen, Bjørn Hols. Generation of an isogenic, gene-corrected control cell line of the spinocerebellar ataxia type 2 patient-derived iPSC line H266. Stem cell research. vol 16. issue 1. 2016-12-13. PMID:27345815. |
spinocerebellar ataxia type 2 (sca2) is a neurodegenerative disease primarily affecting the cerebellum. |
2016-12-13 |
2023-08-13 |
Not clear |
| Jan Cendeli. Transplantation and Stem Cell Therapy for Cerebellar Degenerations. Cerebellum (London, England). vol 15. issue 1. 2016-10-21. PMID:26155762. |
stem cell-based and regenerative therapy may become a hopeful treatment for neurodegenerative diseases including hereditary cerebellar degenerations. |
2016-10-21 |
2023-08-13 |
mouse |
| Rosanna Beraldi, Chun-Hung Chan, Christopher S Rogers, Attila D Kovács, David K Meyerholz, Constantin Trantzas, Allyn M Lambertz, Benjamin W Darbro, Krystal L Weber, Katherine A M White, Richard V Rheeden, Michael C Kruer, Brian A Dacken, Xiao-Jun Wang, Bryan T Davis, Judy A Rohret, Jason T Struzynski, Frank A Rohret, Jill M Weimer, David A Pearc. A novel porcine model of ataxia telangiectasia reproduces neurological features and motor deficits of human disease. Human molecular genetics. vol 24. issue 22. 2016-09-12. PMID:26374845. |
at is a neurodegenerative disease primarily characterized by cerebellar degeneration in children leading to motor impairment. |
2016-09-12 |
2023-08-13 |
human |
| Sarah Doss, Jan Leo Rinnenthal, Tanja Schmitz-Hübsch, Alexander U Brandt, Sebastian Papazoglou, Silke Lux, Stephan Maul, Jens Würfel, Matthias Endres, Thomas Klockgether, Martina Minnerop, Friedemann Pau. Cerebellar neurochemical alterations in spinocerebellar ataxia type 14 appear to include glutathione deficiency. Journal of neurology. vol 262. issue 8. 2016-06-22. PMID:26041613. |
in the cerebellum, we found in addition to signs of neurodegeneration a glutathione reduction, which has been associated with cellular damage by oxidative stress in other neurodegenerative diseases such as parkinson's disease and friedreich's ataxia. |
2016-06-22 |
2023-08-13 |
Not clear |
| Xinlu Li, Marie Ménade, Guennadi Kozlov, Zheping Hu, Zheng Dai, Peter S McPherson, Bernard Brais, Kalle Gehrin. High-Throughput Screening for Ligands of the HEPN Domain of Sacsin. PloS one. vol 10. issue 9. 2016-06-17. PMID:26366743. |
sacsin is a large protein implicated in the neurodevelopmental and neurodegenerative disease autosomal recessive spastic ataxia of charlevoix-saguenay (arsacs), which features the loss of purkinje neurons in the cerebellum. |
2016-06-17 |
2023-08-13 |
Not clear |
| Susanne A Schneide. Neurodegeneration with Brain Iron Accumulation. Current neurology and neuroscience reports. vol 16. issue 1. 2016-05-12. PMID:26739693. |
they clinically present as neurodegenerative diseases with progressive hypo- and/or hyperkinetic movement disorders and a variable degree of pyramidal, cerebellar, peripheral nerve, autonomic, cognitive and psychiatric involvement, and visual dysfunction. |
2016-05-12 |
2023-08-13 |
Not clear |