All Relations between Neurodegenerative Diseases and cerebellum

Publication Sentence Publish Date Extraction Date Species
Hiroyoshi Arig. Common mechanisms of onset of cancer and neurodegenerative diseases. Biological & pharmaceutical bulletin. vol 38. issue 6. 2016-02-21. PMID:26027820. among these proteins, some proteins have been found to be also responsible for the onset of neurodegenerative diseases, including parkinson's disease, retinitis pigmentosa and cerebellar atrophy. 2016-02-21 2023-08-13 Not clear
Xuejing Wang, Hui Wang, Yujun Xia, Hong Jiang, Lu Shen, Shoubiao Wang, Ruowu Shen, Qian Xu, Xuegang Luo, Beisha Tan. Spinocerebellar ataxia type 6: Systematic patho-anatomical study reveals different phylogenetically defined regions of the cerebellum and neural pathways undergo different evolutions of the degenerative process. Neuropathology : official journal of the Japanese Society of Neuropathology. vol 30. issue 5. 2016-02-17. PMID:20113406. our detailed postmortem findings confirmed that sca6 was not a simple "pure" cerebellar disease, but a complex neurodegenerative disease in which the three cerebellar regions underwent different evolutions of neurodegeneration process, and the corresponding precerebellar nuclei and the neural pathway were all involved. 2016-02-17 2023-08-12 Not clear
Jose-Alberto Palma, Horacio Kaufman. Novel therapeutic approaches in multiple system atrophy. Clinical autonomic research : official journal of the Clinical Autonomic Research Society. vol 25. issue 1. 2016-02-11. PMID:24928797. multiple system atrophy (msa) is a sporadic, adult onset, relentlessly progressive neurodegenerative disease characterized by autonomic abnormalities associated with parkinsonism, cerebellar dysfunction, pyramidal signs, or combinations thereof. 2016-02-11 2023-08-13 mouse
Sara Capoccia, Federica Maccarinelli, Barbara Buffoli, Luigi F Rodella, Ottavio Cremona, Paolo Arosio, Francesca Cirull. Behavioral characterization of mouse models of neuroferritinopathy. PloS one. vol 10. issue 2. 2016-01-08. PMID:25689865. nucleotide insertions in the last exon of the ferritin light chain cause a neurodegenerative disease known as neuroferritinopathy, characterized by iron deposition in the brain, particularly in the cerebellum, basal ganglia and motor cortex. 2016-01-08 2023-08-13 mouse
M Cvetanovic, M Ingram, H Orr, P Opa. Early activation of microglia and astrocytes in mouse models of spinocerebellar ataxia type 1. Neuroscience. vol 289. 2015-12-01. PMID:25595967. spinocerebellar ataxia type 1 (sca1) is an incurable, dominantly inherited neurodegenerative disease of the cerebellum caused by a polyglutamine-repeat expansion in the protein ataxin-1 (atxn1). 2015-12-01 2023-08-13 mouse
Marija Cvetanovi. Decreased expression of glutamate transporter GLAST in Bergmann glia is associated with the loss of Purkinje neurons in the spinocerebellar ataxia type 1. Cerebellum (London, England). vol 14. issue 1. 2015-10-23. PMID:25255716. spinocerebellar ataxia type 1 (sca1) is a dominantly inherited neurodegenerative disease of the cerebellum caused by a polyglutamine-repeat expansion in the protein atxn1. 2015-10-23 2023-08-13 mouse
Soon-Tae Lee, Kon Chu, Keun-Hwa Jung, Jae-Jun Ban, Woo-Seok Im, Hee-Yeon Jo, Ji-Hyun Park, Ji-Yeon Lim, Jung-Won Shin, Jangsup Moon, Sang Kun Lee, Manho Kim, Jae-Kyu Ro. Altered expression of miR-202 in cerebellum of multiple-system atrophy. Molecular neurobiology. vol 51. issue 1. 2015-10-20. PMID:24981430. cerebellar degeneration is a devastating manifestation of cerebellar-type multiple-system atrophy (msa), a rapidly progressive neurodegenerative disease, and the exact pathogenesis is unknown. 2015-10-20 2023-08-13 human
Monica Gagliardi, Maurizio Morelli, Grazia Annesi, Giuseppe Nicoletti, Paolo Perrotta, Giuseppe Pustorino, Grazia Iannello, Patrizia Tarantino, Antonio Gambardella, Aldo Quattron. A new SLC20A2 mutation identified in southern Italy family with primary familial brain calcification. Gene. vol 568. issue 1. 2015-08-19. PMID:25958344. primary familial brain calcification (pfbc) is a rare neurodegenerative disease characterized by bilateral calcifications mostly located in the basal ganglia and in the thalami, cerebellum and subcortical white matter. 2015-08-19 2023-08-13 Not clear
Lucía Calatrava-Ferreras, Rafael Gonzalo-Gobernado, Diana Reimers, Antonio S Herranz, Adriano Jiménez-Escrig, Juan José Díaz-Gil, María José Casarejos, María Teresa Montero-Vega, Eulalia Bazá. Neuroprotective role of liver growth factor "LGF" in an experimental model of cerebellar ataxia. International journal of molecular sciences. vol 15. issue 10. 2015-06-19. PMID:25338046. cerebellar ataxias (ca) comprise a heterogeneous group of neurodegenerative diseases characterized by a lack of motor coordination. 2015-06-19 2023-08-13 rat
M Strupp, O Kremmyda, C Adamczyk, N Böttcher, C Muth, C W Yip, T Bremov. Central ocular motor disorders, including gaze palsy and nystagmus. Journal of neurology. vol 261 Suppl 2. 2015-04-20. PMID:25145891. dbn is generally due to cerebellar dysfunction affecting the flocculus bilaterally (e.g., due to a neurodegenerative disease). 2015-04-20 2023-08-13 Not clear
Yvonne L Clarkson, Emma M Perkins, Callum J Cairncross, Alastair R Lyndon, Paul A Skehel, Mandy Jackso. β-III spectrin underpins ankyrin R function in Purkinje cell dendritic trees: protein complex critical for sodium channel activity is impaired by SCA5-associated mutations. Human molecular genetics. vol 23. issue 14. 2015-02-09. PMID:24603075. spinocerebellar ataxia type 5 (sca5) and spectrin associated autosomal recessive cerebellar ataxia type 1 are human neurodegenerative diseases involving progressive gait ataxia and cerebellar atrophy. 2015-02-09 2023-08-12 human
Victor Galvez, Rosalinda Diaz, Carlos Roberto Hernandez-Castillo, Aurelio Campos-Romo, Juan Fernandez-Rui. Olfactory performance in spinocerebellar ataxia type 7 patients. Parkinsonism & related disorders. vol 20. issue 5. 2015-01-07. PMID:24629799. based on the olfactory dysfunction found in different neurodegenerative diseases and functional neuroimaging data showing cerebellar activation during olfaction, we hypothesized that sca7 patients would show an olfactory impairment. 2015-01-07 2023-08-12 Not clear
Yasmine T Asi, Julie E Simpson, Paul R Heath, Stephen B Wharton, Andrew J Lees, Tamas Revesz, Henry Houlden, Janice L Holto. Alpha-synuclein mRNA expression in oligodendrocytes in MSA. Glia. vol 62. issue 6. 2014-12-15. PMID:24590631. multiple system atrophy (msa) is a progressive neurodegenerative disease presenting clinically with parkinsonian, cerebellar, and autonomic features. 2014-12-15 2023-08-12 human
Dusan Roncevic, Jose-Alberto Palma, Jose Martinez, Niamh Goulding, Lucy Norcliffe-Kaufmann, Horacio Kaufman. Cerebellar and parkinsonian phenotypes in multiple system atrophy: similarities, differences and survival. Journal of neural transmission (Vienna, Austria : 1996). vol 121. issue 5. 2014-12-12. PMID:24337696. multiple system atrophy (msa) is a neurodegenerative disease with two motor phenotypes: parkinsonian (msa-p) and cerebellar (msa-c). 2014-12-12 2023-08-12 Not clear
Scoty M Hearst, Qingmei Shao, Mariper Lopez, Drazen Raucher, Parminder J S Vi. The design and delivery of a PKA inhibitory polypeptide to treat SCA1. Journal of neurochemistry. vol 131. issue 1. 2014-11-21. PMID:24903464. spinocerebellar ataxia-1 (sca1) is a neurodegenerative disease that primarily targets purkinje cells (pcs) of the cerebellum. 2014-11-21 2023-08-13 Not clear
Carmen Rodríguez-Cueto, Cristina Benito, Javier Fernández-Ruiz, Julián Romero, Mariluz Hernández-Gálvez, María Gómez-Rui. Changes in CB(1) and CB(2) receptors in the post-mortem cerebellum of humans affected by spinocerebellar ataxias. British journal of pharmacology. vol 171. issue 6. 2014-11-05. PMID:23808969. spinocerebellar ataxias (scas) are a family of chronic progressive neurodegenerative diseases, clinically and genetically heterogeneous, characterized by loss of balance and motor coordination due to degeneration of the cerebellum and its afferent and efferent connections. 2014-11-05 2023-08-12 Not clear
M Dhruba Singh, Kritika Raj, Surajit Sarka. Drosophila Myc, a novel modifier suppresses the poly(Q) toxicity by modulating the level of CREB binding protein and histone acetylation. Neurobiology of disease. vol 63. 2014-09-19. PMID:24291519. polyglutamine or poly(q) disorders are dominantly inherited neurodegenerative diseases characterised by progressive loss of neurons in cerebellum, basal ganglia and cortex in adult human brain. 2014-09-19 2023-08-12 human
Tania F Gendron, Kevin F Bieniek, Yong-Jie Zhang, Karen Jansen-West, Peter E A Ash, Thomas Caulfield, Lillian Daughrity, Judith H Dunmore, Monica Castanedes-Casey, Jeannie Chew, Danielle M Cosio, Marka van Blitterswijk, Wing C Lee, Rosa Rademakers, Kevin B Boylan, Dennis W Dickson, Leonard Petrucell. Antisense transcripts of the expanded C9ORF72 hexanucleotide repeat form nuclear RNA foci and undergo repeat-associated non-ATG translation in c9FTD/ALS. Acta neuropathologica. vol 126. issue 6. 2014-07-10. PMID:24129584. of importance, foci composed of antisense transcripts are observed in the frontal cortex, spinal cord and cerebellum of c9ftd/als cases, and neuronal inclusions of poly(pr), poly(gp) and poly(pa) are present in various brain tissues in c9ftd/als, but not in other neurodegenerative diseases, including cag repeat disorders. 2014-07-10 2023-08-12 human
Giovanna Calandra-Buonaura, Pietro Guaraldi, Luisa Sambati, Giovanna Lopane, Annagrazia Cecere, Giorgio Barletta, Federica Provini, Manuela Contin, Paolo Martinelli, Pietro Cortell. Multiple system atrophy with prolonged survival: is late onset of dysautonomia the clue? Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. vol 34. issue 10. 2014-06-02. PMID:23728718. multiple system atrophy (msa) is a neurodegenerative disease characterised by cardiovascular autonomic failure and/or urinary dysfunctions, associated with parkinsonism, cerebellar and/or corticospinal signs, usually leading to death after an average of 7 years. 2014-06-02 2023-08-12 Not clear
Matthis Synofzik, Michael A Gonzalez, Charles Marques Lourenco, Marie Coutelier, Tobias B Haack, Adriana Rebelo, Didier Hannequin, Tim M Strom, Holger Prokisch, Christoph Kernstock, Alexandra Durr, Ludger Schöls, Marcos M Lima-Martínez, Amjad Farooq, Rebecca Schüle, Giovanni Stevanin, Wilson Marques, Stephan Züchne. PNPLA6 mutations cause Boucher-Neuhauser and Gordon Holmes syndromes as part of a broad neurodegenerative spectrum. Brain : a journal of neurology. vol 137. issue Pt 1. 2014-03-11. PMID:24355708. our findings show that pnpla6 influences a manifold of neuronal systems, from the retina to the cerebellum, upper and lower motor neurons and the neuroendocrine system, with damage of this protein causing an extraordinarily broad continuous spectrum of associated neurodegenerative disease. 2014-03-11 2023-08-12 Not clear