All Relations between Polyneuropathies and paracentral nucleus thalamus (gurdjian 1927)
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Joseph I Berger, Kasun Vernon, Farid Abdo, Sandeep Gulati, Radhika Harihara. Looks Like Neurosyphilis, Feels Like Guillain-Barre: At the Confluence of Infection and Immunology. Cureus. vol 14. issue 6. 2022-08-01. PMID:35911366. |
human immunodeficiency virus (hiv) testing was negative. lyme disease testing was negative. nerve conduction studies (ncs) and electromyography (emg) showed a sensorimotor polyneuropathy with mixed demyelinating and axonal features. ivig was continued for a total of five days, and antibiotics were changed to penicillin g (pcn g) for a total of 14 days for definitive treatment of early neurosyphilis (ns). while both clinical and laboratory findings confirm a positive diagnosis of ns, the patient's csf composition showed very elevated total protein levels and pleocytosis. additionally, his early peripheral neuropathy and emg findings are not characteristics of a single disease and, instead, suggested a mixed pathology. we postulate that this patient had confirmed secondary syphilis with early ns associated with, and possibly correlated with, a simultaneous episode of acute inflammatory demyelinating polyneuropathy (aidp) and/or a vaccine-related phenomenon. |
2022-08-01 |
2023-08-14 |
human |
H Driedger, W Pruzansk. Plasma cell neoplasia with peripheral polyneuropathy. A study of five cases and a review of the literature. Medicine. vol 59. issue 4. 1980-09-28. PMID:6248719. |
peripheral polyneuropathy (ppn) is a rare complication of plasma cell neoplasia (pcn), occurring in less than one percent of the patients. |
1980-09-28 |
2023-08-12 |
Not clear |