All Relations between Spinocerebellar Ataxias and cerebellum

Publication Sentence Publish Date Extraction Date Species
Satsuki Noma, Wakana Ohya-Shimada, Masaaki Kanai, Keiji Ueda, Toshikazu Nakamura, Hiroshi Funakosh. Overexpression of HGF attenuates the degeneration of Purkinje cells and Bergmann glia in a knockin mouse model of spinocerebellar ataxia type 7. Neuroscience research. vol 73. issue 2. 2013-02-19. PMID:22426494. spinocerebellar ataxia type 7 (sca7) is an autosomal dominant disorder associated with cerebellar neurodegeneration caused by expansion of a cag repeat in the ataxin-7 gene. 2013-02-19 2023-08-12 mouse
Koen L I van Gassen, Charlotte D C C van der Heijden, Susanne T de Bot, Wilfred F A den Dunnen, Leonard H van den Berg, Corien C Verschuuren-Bemelmans, H P H Kremer, Jan H Veldink, Erik-Jan Kamsteeg, Hans Scheffer, Bart P van de Warrenbur. Genotype-phenotype correlations in spastic paraplegia type 7: a study in a large Dutch cohort. Brain : a journal of neurology. vol 135. issue Pt 10. 2013-01-15. PMID:22964162. an overlapping phenotypic presentation with its biological counterpart afg3l2, which when mutated causes spinocerebellar ataxia type 28, is apparent and possibly suggests that abnormal levels of the spg7 protein impact the function of the mitochondrial atpases associated with diverse cellular activities-protease complex (formed by spg7 and afg3l2) in the cerebellum. 2013-01-15 2023-08-12 Not clear
Alexis Trott, Lucien J Houeno. Mini-review: spinocerebellar ataxias: an update of SCA genes. Recent patents on DNA & gene sequences. vol 6. issue 2. 2013-01-09. PMID:22670601. autosomal dominant spinocerebellar ataxias (scas) are a complex group of debilitating and neurodegenerative diseases that affect the cerebellum and its main connections and characterized by a generalized incoordination of gait, speech, and limb movements. 2013-01-09 2023-08-12 Not clear
W Scherzed, E R Brunt, H Heinsen, R A de Vos, K Seidel, K Bürk, L Schöls, G Auburger, D Del Turco, T Deller, H W Korf, W F den Dunnen, U Rü. Pathoanatomy of cerebellar degeneration in spinocerebellar ataxia type 2 (SCA2) and type 3 (SCA3). Cerebellum (London, England). vol 11. issue 3. 2012-12-11. PMID:22198871. pathoanatomy of cerebellar degeneration in spinocerebellar ataxia type 2 (sca2) and type 3 (sca3). 2012-12-11 2023-08-12 Not clear
W Scherzed, E R Brunt, H Heinsen, R A de Vos, K Seidel, K Bürk, L Schöls, G Auburger, D Del Turco, T Deller, H W Korf, W F den Dunnen, U Rü. Pathoanatomy of cerebellar degeneration in spinocerebellar ataxia type 2 (SCA2) and type 3 (SCA3). Cerebellum (London, England). vol 11. issue 3. 2012-12-11. PMID:22198871. the cerebellum is one of the well-known targets of the pathological processes underlying spinocerebellar ataxia type 2 (sca2) and type 3 (sca3). 2012-12-11 2023-08-12 Not clear
Kathrin Reetz, Imis Dogan, Arndt Rolfs, Ferdinand Binkofski, Jörg B Schulz, Angela R Laird, Peter T Fox, Simon B Eickhof. Investigating function and connectivity of morphometric findings--exemplified on cerebellar atrophy in spinocerebellar ataxia 17 (SCA17). NeuroImage. vol 62. issue 3. 2012-12-10. PMID:22659444. investigating function and connectivity of morphometric findings--exemplified on cerebellar atrophy in spinocerebellar ataxia 17 (sca17). 2012-12-10 2023-08-12 human
Heike Jacobi, Till-Karsten Hauser, Paola Giunti, Christoph Globas, Peter Bauer, Tanja Schmitz-Hübsch, László Baliko, Alessandro Filla, Caterina Mariotti, Maria Rakowicz, Perine Charles, Pascale Ribai, Sandra Szymanski, Jon Infante, Bart P C van de Warrenburg, Alexandra Dürr, Dagmar Timmann, Sylvia Boesch, Roberto Fancellu, Rafal Rola, Chantal Depondt, Ludger Schöls, Elzbieta Zdzienicka, Jun-Suk Kang, Susanne Ratzka, Berry Kremer, Dennis A Stephenson, Béla Melegh, Massimo Pandolfo, Sophie Tezenas du Montcel, Johannes Borkert, Jörg B Schulz, Thomas Klockgethe. Spinocerebellar ataxia types 1, 2, 3 and 6: the clinical spectrum of ataxia and morphometric brainstem and cerebellar findings. Cerebellum (London, England). vol 11. issue 1. 2012-12-04. PMID:21701895. spinocerebellar ataxia types 1, 2, 3 and 6: the clinical spectrum of ataxia and morphometric brainstem and cerebellar findings. 2012-12-04 2023-08-12 Not clear
Heike Jacobi, Till-Karsten Hauser, Paola Giunti, Christoph Globas, Peter Bauer, Tanja Schmitz-Hübsch, László Baliko, Alessandro Filla, Caterina Mariotti, Maria Rakowicz, Perine Charles, Pascale Ribai, Sandra Szymanski, Jon Infante, Bart P C van de Warrenburg, Alexandra Dürr, Dagmar Timmann, Sylvia Boesch, Roberto Fancellu, Rafal Rola, Chantal Depondt, Ludger Schöls, Elzbieta Zdzienicka, Jun-Suk Kang, Susanne Ratzka, Berry Kremer, Dennis A Stephenson, Béla Melegh, Massimo Pandolfo, Sophie Tezenas du Montcel, Johannes Borkert, Jörg B Schulz, Thomas Klockgethe. Spinocerebellar ataxia types 1, 2, 3 and 6: the clinical spectrum of ataxia and morphometric brainstem and cerebellar findings. Cerebellum (London, England). vol 11. issue 1. 2012-12-04. PMID:21701895. to assess the clinical spectrum of ataxia and cerebellar oculomotor deficits in the most common spinocerebellar ataxias (scas), we analysed the baseline data of the eurosca natural history study, a multicentric cohort study of 526 patients with either spinocerebellar ataxia type 1, 2, 3 or 6. 2012-12-04 2023-08-12 Not clear
Brian C Jung, Soo I Choi, Annie X Du, Jennifer L Cuzzocreo, Howard S Ying, Bennett A Landman, Susan L Perlman, Robert W Baloh, David S Zee, Arthur W Toga, Jerry L Prince, Sarah H Yin. MRI shows a region-specific pattern of atrophy in spinocerebellar ataxia type 2. Cerebellum (London, England). vol 11. issue 1. 2012-12-04. PMID:21850525. in this study, we used manual delineation of high-resolution magnetic resonance imaging (mri) to determine the spatial and temporal characteristics of the cerebellar atrophy in spinocerebellar ataxia type 2 (sca2). 2012-12-04 2023-08-12 human
Mariana Moscovich, Renato Puppi Munhoz, Helio A Teive, Salmo Raskin, Margarete de J Carvalho, Egberto R Barbosa, Ronald Ranvaud, Jilin Liu, Karen McFarland, Tetsuo Ashizawa, Andrew J Lees, Laura Silveira-Moriyam. Olfactory impairment in familial ataxias. Journal of neurology, neurosurgery, and psychiatry. vol 83. issue 10. 2012-11-27. PMID:22791905. the main clinical manifestations of the spinocerebellar ataxias (scas) result from the involvement of the cerebellum and its connections. 2012-11-27 2023-08-12 Not clear
Zhao Chen, Xiaohui Li, Beisha Tang, Junling Wang, Yuting Shi, Zhanfang Sun, Li Zhang, Qian Pan, Kun Xia, Hong Jian. Spinocerebellar ataxia type 27 (SCA27) is an uncommon cause of dominant ataxia among Chinese Han population. Neuroscience letters. vol 520. issue 1. 2012-10-04. PMID:22579694. autosomal dominant cerebellar ataxias (adcas), genetically classified into spinocerebellar ataxias (scas), are a highly heterogeneous group of neurodegenerative disorders. 2012-10-04 2023-08-12 Not clear
S Furtado, S Das, O Suchowersk. A review of the inherited ataxias: recent advances in genetic, clinical and neuropathologic aspects. Parkinsonism & related disorders. vol 4. issue 4. 2012-10-02. PMID:18591106. autosomal dominant cerebellar ataxias (adcas) include spinocerebellar ataxias (scas) and dentatorubral-pallidoluysian atrophy (drpla); six of these have been found to be trinucleotide repeat disorders. 2012-10-02 2023-08-12 Not clear
Ashok K Kayal, Munindra Goswami, Marami Das, Hussain Masara. A case of Spinocerebellar Ataxia from ethnic tribe of Assam. Annals of Indian Academy of Neurology. vol 14. issue 2. 2012-10-02. PMID:21808476. here we present the case of a 17-year-old girl belonging to an ethnic tribe (bodo tribe) of assam, presenting with bilateral cerebellar signs and with history suggestive of an autosomal dominant pattern of inheritance, who was found to have spinocerebellar ataxia 7 on genetic testing. 2012-10-02 2023-08-12 Not clear
Hirokazu Hira. Basic research on cerebellar gene therapy using lentiviral vectors. Cerebellum (London, England). vol 11. issue 2. 2012-09-19. PMID:22120847. using our method, various experiments were carried out to study the pathophysiology of the cerebellum, including the investigation of a cerebellum-specific gene of unknown function, the generation and analysis of a mouse model of the spinocerebellar ataxia, and the rescue of an ataxic phenotype in mutant mice by introducing a defective gene or a therapeutic gene into the purkinje cells. 2012-09-19 2023-08-12 mouse
Lifang Lei, Yunjie Liao, Weihua Liao, Jie Zhou, Yi Yuan, Junling Wang, Hong Jiang, Lu Shen, Beisha Tan. Magnetic resonance spectroscopy of the cerebellum in patients with spinocerebellar ataxia type 3/Machado-Joseph disease. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences. vol 36. issue 6. 2012-09-06. PMID:21743142. magnetic resonance spectroscopy of the cerebellum in patients with spinocerebellar ataxia type 3/machado-joseph disease. 2012-09-06 2023-08-12 Not clear
Lifang Lei, Yunjie Liao, Weihua Liao, Jie Zhou, Yi Yuan, Junling Wang, Hong Jiang, Lu Shen, Beisha Tan. Magnetic resonance spectroscopy of the cerebellum in patients with spinocerebellar ataxia type 3/Machado-Joseph disease. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences. vol 36. issue 6. 2012-09-06. PMID:21743142. to evaluate the metabolite pattern and the severity in patients with spinocerebellar ataxia type 3/ machado-joseph disease (sca3/mjd) by (1)h magnetic resonance spectroscopy ((1)h-mrs) on different cerebellar regions, including cerebellar vermis, cerebellar peduncles, cerebellar cortex, and dentatum. 2012-09-06 2023-08-12 Not clear
Mariela Guevara-García, Lizette Gil-del Valle, Luis Velásquez-Pérez, Julio César García-Rodrígue. Oxidative stress as a cofactor in spinocerebellar ataxia type 2. Redox report : communications in free radical research. vol 17. issue 2. 2012-09-06. PMID:22564351. spinocerebellar ataxia type 2 (sca2) is a redox-sensitive neurodegenerative disease affecting the cerebellum, fibre connections in the cerebellum, the peripheral nervous system, and extracerebellar central pathways. 2012-09-06 2023-08-12 Not clear
A Castrioto, P Prontera, E Di Gregorio, V Rossi, L Parnetti, A Rossi, E Donti, A Brusco, P Calabresi, N Tambasc. A novel spinocerebellar ataxia type 15 family with involuntary movements and cognitive decline. European journal of neurology. vol 18. issue 10. 2012-06-19. PMID:21382133. sca15 is a recently identified spinocerebellar ataxia with pure cerebellar involvement. 2012-06-19 2023-08-12 Not clear
M Traoré, T Coulibaly, K G Meilleur, A La Pean, M Sangaré, G Landouré, F Mochel, M Karambé, C O Guinto, K H Fischbec. Clinical and genetic analysis of spinocerebellar ataxia in Mali. European journal of neurology. vol 18. issue 10. 2012-06-19. PMID:21418439. autosomal dominant cerebellar ataxia, currently denominated spinocerebellar ataxia (scas), represents a heterogeneous group of neurodegenerative disorders affecting the cerebellum and its connections. 2012-06-19 2023-08-12 Not clear
Keiko Shimojima, Akihisa Okumura, Jun Natsume, Kaori Aiba, Hirokazu Kurahashi, Tetsuo Kubota, Kenji Yokochi, Toshiyuki Yamamot. Spinocerebellar ataxias type 27 derived from a disruption of the fibroblast growth factor 14 gene with mimicking phenotype of paroxysmal non-kinesigenic dyskinesia. Brain & development. vol 34. issue 3. 2012-06-04. PMID:21600715. many types of spinocerebellar ataxias (scas) manifest as progressive disorders with cerebellar involvement. 2012-06-04 2023-08-12 Not clear