| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| David D Bushart, Vikram G Shakkotta. Vulnerability of Human Cerebellar Neurons to Degeneration in Ataxia-Causing Channelopathies. Frontiers in systems neuroscience. vol 16. 2022-06-27. PMID:35757096. |
we also speculate on the vulnerability of cerebellar neurons to degeneration in mouse models of spinocerebellar ataxia (sca) where ion channel transcript dysregulation has recently been implicated in disease pathogenesis. |
2022-06-27 |
2023-08-14 |
mouse |
| Hung-Chieh Chen, Li-Hua Lee, Jiing-Feng Lirng, Bing-Wen Soon. Radiological hints for differentiation of cerebellar multiple system atrophy from spinocerebellar ataxia. Scientific reports. vol 12. issue 1. 2022-06-22. PMID:35732792. |
radiological hints for differentiation of cerebellar multiple system atrophy from spinocerebellar ataxia. |
2022-06-22 |
2023-08-14 |
Not clear |
| Hung-Chieh Chen, Li-Hua Lee, Jiing-Feng Lirng, Bing-Wen Soon. Radiological hints for differentiation of cerebellar multiple system atrophy from spinocerebellar ataxia. Scientific reports. vol 12. issue 1. 2022-06-22. PMID:35732792. |
differentiation cerebellar multiple systemic atrophy (msa-c) from spinocerebellar ataxia (sca) is important. |
2022-06-22 |
2023-08-14 |
Not clear |
| Pauline Bohne, Max Rybarski, Damian Boden-El Mourabit, Felix Krause, Melanie D Mar. Cerebellar contribution to threat probability in a SCA6 mouse model. Human molecular genetics. 2022-06-16. PMID:35708512. |
in this study we investigated the cerebellar contribution in evoking appropriate defensive escape behavior using a purely cerebellar, neurodegenerative mouse model for spinocerebellar ataxia type 6 (sca6) which is caused by an expanded cag repeat in exon 47 of the p/q type calcium channel α1a subunit. |
2022-06-16 |
2023-08-14 |
mouse |
| Kristin Mayoral-Palarz, Andreia Neves-Carvalho, Sara Duarte-Silva, Daniela Monteiro-Fernandes, Patrícia Maciel, Kamran Khodakha. Cerebellar neuronal dysfunction accompanies early motor symptoms in spinocerebellar ataxia type 3. Disease models & mechanisms. 2022-06-06. PMID:35660856. |
cerebellar neuronal dysfunction accompanies early motor symptoms in spinocerebellar ataxia type 3. |
2022-06-06 |
2023-08-14 |
mouse |
| Francesco Gentile, Alessandro Bertini, Alberto Priori, Tommaso Bocc. Movement disorders and neuropathies: overlaps and mimics in clinical practice. Journal of neurology. 2022-06-03. PMID:35657406. |
finally, genetic causes should be pursued in case of positive family history, young onset or multisystemic involvement, and examined for neuroacanthocytosis, spinocerebellar ataxias, mitochondrial disorders and less common causes of adult-onset cerebellar ataxias and spastic paraparesis. |
2022-06-03 |
2023-08-14 |
Not clear |
| Xin-Yuan Chen, Yan-Hua Lian, Xia-Hua Liu, Arif Sikandar, Meng-Cheng Li, Hao-Ling Xu, Jian-Ping Hu, Qun-Lin Chen, Shi-Rui Ga. Effects of Repetitive Transcranial Magnetic Stimulation on Cerebellar Metabolism in Patients With Spinocerebellar Ataxia Type 3. Frontiers in aging neuroscience. vol 14. 2022-05-13. PMID:35547622. |
effects of repetitive transcranial magnetic stimulation on cerebellar metabolism in patients with spinocerebellar ataxia type 3. |
2022-05-13 |
2023-08-13 |
Not clear |
| Roderick P P W M Maas, Steven Teerenstra, Ivan Toni, Thomas Klockgether, Dennis J L G Schutter, Bart P C van de Warrenbur. Cerebellar Transcranial Direct Current Stimulation in Spinocerebellar Ataxia Type 3: a Randomized, Double-Blind, Sham-Controlled Trial. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. 2022-05-02. PMID:35501469. |
cerebellar transcranial direct current stimulation in spinocerebellar ataxia type 3: a randomized, double-blind, sham-controlled trial. |
2022-05-02 |
2023-08-13 |
Not clear |
| Roderick P P W M Maas, Steven Teerenstra, Ivan Toni, Thomas Klockgether, Dennis J L G Schutter, Bart P C van de Warrenbur. Cerebellar Transcranial Direct Current Stimulation in Spinocerebellar Ataxia Type 3: a Randomized, Double-Blind, Sham-Controlled Trial. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. 2022-05-02. PMID:35501469. |
the objective of this study was to investigate if a two-week regimen of daily cerebellar tdcs sessions diminishes ataxia and non-motor symptom severity and alters cerebellar-m1 connectivity in individuals with spinocerebellar ataxia type 3 (sca3). |
2022-05-02 |
2023-08-13 |
Not clear |
| Hui Chen, Limeng Dai, Yuhan Zhang, Liu Feng, Zhenzhen Jiang, Xingang Wang, Dongjing Xie, Jing Guo, Huafu Chen, Jian Wang, Chen Li. Network Reconfiguration Among Cerebellar Visual, Frontiers in aging neuroscience. vol 14. 2022-04-28. PMID:35478700. |
network reconfiguration among cerebellar visual, spinocerebellar ataxia type 3 (sca3) is a rare movement disorder characterized with ataxia. |
2022-04-28 |
2023-08-13 |
Not clear |
| Anton N Shuvaev, Olga S Belozor, Oleg I Mozhei, Aleksandra G Mileiko, Ludmila D Mosina, Irina V Laletina, Ilia G Mikhailov, Yana V Fritsler, Andrey N Shuvaev, Anja G Teschemacher, Sergey Kasparo. Memantine Disrupts Motor Coordination through Anxiety-like Behavior in CD1 Mice. Brain sciences. vol 12. issue 4. 2022-04-21. PMID:35448027. |
we previously used memantine to prevent functional damage and to retain morphology of cerebellar neurons and bergmann glia in an optogenetic mouse model of spinocerebellar ataxia type-1 (sca1). |
2022-04-21 |
2023-08-13 |
mouse |
| Jiaqi Wang, Atsuhiko Sugiyama, Hajime Yokota, Shigeki Hirano, Graham Cooper, Hiroki Mukai, Kenji Ohira, Kyosuke Koide, Shoichi Ito, Carsten Finke, Alexander U Brandt, Friedemann Paul, Satoshi Kuwabar. Diagnostic efficacy of the magnetic resonance T1w/T2w ratio for the middle cerebellar peduncle in multiple system atrophy and spinocerebellar ataxia: A preliminary study. PloS one. vol 17. issue 4. 2022-04-15. PMID:35427382. |
diagnostic efficacy of the magnetic resonance t1w/t2w ratio for the middle cerebellar peduncle in multiple system atrophy and spinocerebellar ataxia: a preliminary study. |
2022-04-15 |
2023-08-13 |
Not clear |
| A Umano, K Fang, Z Qu, J B Scaglione, S Altinok, C J Treadway, E T Wick, E Paulakonis, C Karunanayake, S Chou, T M Bardakjian, P Gonzalez-Alegre, R C Page, J C Schisler, N G Brown, D Yan, K M Scaglion. The molecular basis of spinocerebellar ataxia type 48 caused by a de novo mutation in the ubiquitin ligase CHIP. The Journal of biological chemistry. 2022-04-10. PMID:35398354. |
the spinocerebellar ataxias (scas) are a class of incurable diseases characterized by degeneration of the cerebellum that results in movement disorder. |
2022-04-10 |
2023-08-13 |
Not clear |
| Hiroshi Mitoma, Kazuhiko Yamaguchi, Jerome Honnorat, Mario Mant. The Clinical Concept of LTDpathy: Is Dysregulated LTD Responsible for Prodromal Cerebellar Symptoms? Brain sciences. vol 12. issue 3. 2022-03-25. PMID:35326260. |
on the other hand, in some types of spinocerebellar ataxia (sca), dysfunction in pf-pc ltd, and impairments of pf-pc ltd-related adaptive behaviors (including vestibulo-ocular reflex (vor) and prism adaptation) appear during the prodromal stage, well before the manifestations of obvious cas and cerebellar atrophy. |
2022-03-25 |
2023-08-13 |
Not clear |
| Marc Corral-Juan, Pilar Casquero, Natalia Giraldo-Restrepo, Steve Laurie, Alicia Martinez-Piñeiro, Raidili Cristina Mateo-Montero, Lourdes Ispierto, Dolores Vilas, Eduardo Tolosa, Victor Volpini, Ramiro Alvarez-Ramo, Ivelisse Sánchez, Antoni Matilla-Dueña. New spinocerebellar ataxia subtype caused by Brain communications. vol 4. issue 2. 2022-03-21. PMID:35310830. |
in this study, we describe a new spinocerebellar ataxia subtype in nine members of a spanish five-generation family from menorca with affected individuals variably presenting with ataxia, nystagmus, dysarthria, polyneuropathy, pyramidal signs, cerebellar atrophy and distinctive cerebral demyelination. |
2022-03-21 |
2023-08-13 |
Not clear |
| Andreas Deistung, Dominik Jäschke, Rossitza Draganova, Viktor Pfaffenrot, Thomas Hulst, Katharina M Steiner, Andreas Thieme, Ilaria A Giordano, Thomas Klockgether, Sinem Tunc, Alexander Münchau, Martina Minnerop, Sophia L Göricke, Jürgen R Reichenbach, Dagmar Timman. Quantitative susceptibility mapping reveals alterations of dentate nuclei in common types of degenerative cerebellar ataxias. Brain communications. vol 4. issue 1. 2022-03-16. PMID:35291442. |
seventy-nine patients with spinocerebellar ataxias of types 1, 2, 3 and 6; 15 patients with friedreich's ataxia; 18 patients with multiple system atrophy, cerebellar type and 111 healthy controls were also included. |
2022-03-16 |
2023-08-13 |
Not clear |
| Andreas Deistung, Dominik Jäschke, Rossitza Draganova, Viktor Pfaffenrot, Thomas Hulst, Katharina M Steiner, Andreas Thieme, Ilaria A Giordano, Thomas Klockgether, Sinem Tunc, Alexander Münchau, Martina Minnerop, Sophia L Göricke, Jürgen R Reichenbach, Dagmar Timman. Quantitative susceptibility mapping reveals alterations of dentate nuclei in common types of degenerative cerebellar ataxias. Brain communications. vol 4. issue 1. 2022-03-16. PMID:35291442. |
spinocerebellar ataxia of type 1 and multiple system atrophy, cerebellar type patients showed higher susceptibilities in large parts of the dentate nucleus but unaltered susceptibility masses compared with controls. |
2022-03-16 |
2023-08-13 |
Not clear |
| Andreas Deistung, Dominik Jäschke, Rossitza Draganova, Viktor Pfaffenrot, Thomas Hulst, Katharina M Steiner, Andreas Thieme, Ilaria A Giordano, Thomas Klockgether, Sinem Tunc, Alexander Münchau, Martina Minnerop, Sophia L Göricke, Jürgen R Reichenbach, Dagmar Timman. Quantitative susceptibility mapping reveals alterations of dentate nuclei in common types of degenerative cerebellar ataxias. Brain communications. vol 4. issue 1. 2022-03-16. PMID:35291442. |
the most striking changes in susceptibility were found in spinocerebellar ataxia of type 1, multiple system atrophy, cerebellar type and spinocerebellar ataxia of type 6. |
2022-03-16 |
2023-08-13 |
Not clear |
| Andreas Deistung, Dominik Jäschke, Rossitza Draganova, Viktor Pfaffenrot, Thomas Hulst, Katharina M Steiner, Andreas Thieme, Ilaria A Giordano, Thomas Klockgether, Sinem Tunc, Alexander Münchau, Martina Minnerop, Sophia L Göricke, Jürgen R Reichenbach, Dagmar Timman. Quantitative susceptibility mapping reveals alterations of dentate nuclei in common types of degenerative cerebellar ataxias. Brain communications. vol 4. issue 1. 2022-03-16. PMID:35291442. |
because iron content is known to be high in glial cells but not in neurons of the cerebellar nuclei, the higher susceptibility in spinocerebellar ataxia of type 1 and multiple system atrophy, cerebellar type may be explained by a reduction of neurons (increase in iron concentration) and/or an increase in iron-rich glial cells, e.g. |
2022-03-16 |
2023-08-13 |
Not clear |
| Hsin Fen Chien, Marise Bueno Zonta, Janini Chen, Giovana Diaferia, Celiana Figueiredo Viana, Hélio Afonso Ghizoni Teive, José Luiz Pedroso, Orlando Graziani Povoas Barsottin. Rehabilitation in patients with cerebellar ataxias. Arquivos de neuro-psiquiatria. 2022-03-03. PMID:35239817. |
cerebellar ataxias comprise a heterogeneous group of diseases characterized by motor and non-motor symptoms, which can be acquired, degenerative, or have a genetic cause, such as spinocerebellar ataxias (sca). |
2022-03-03 |
2023-08-13 |
Not clear |