All Relations between aversion and 5-ht receptor 1a

Reference Sentence Publish Date Extraction Date Species
I Misane, S O Ogre. Multiple 5-HT receptors in passive avoidance: comparative studies of p-chloroamphetamine and 8-OH-DPAT. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology vol 22 issue 2 2000 10649830 The aim of this study was to examine the involvement of multiple 5-HT receptors in passive avoidance (PA) with a focus on 5-HT1A, 5-HT2A, and 5-HT2C receptors. 2000-02-14 2022-01-08 Not clear
K C Lian. Pre- or post-training injection of buspirone impaired retention in the inhibitory avoidance task: involvement of amygdala 5-HT1A receptors. The European journal of neuroscience vol 11 issue 5 1999 10215901 Pre- or post-training injection of buspirone impaired retention in the inhibitory avoidance task: involvement of amygdala 5-HT1A receptors. 1999-05-26 2022-01-08 rat
K C Lian. Pre- or post-training injection of buspirone impaired retention in the inhibitory avoidance task: involvement of amygdala 5-HT1A receptors. The European journal of neuroscience vol 11 issue 5 1999 10215901 These findings suggest that buspirone may modulate memory storage processes in the inhibitory avoidance task through an action on amygdaloid 5-HT1A receptors. 1999-05-26 2022-01-08 rat
F G Graeff, C F Netto, H Zangross. The elevated T-maze as an experimental model of anxiety. Neuroscience and biobehavioral reviews vol 23 issue 2 1999 9884116 The anxiolytic agents diazepam (benzodiazepine), buspirone and ipsapirone (5-HT1A agonists) as well as ritanserin (5-HT2 antagonist) selectively impaired inhibitory avoidance while leaving one-way escape unchanged. 1999-03-29 2022-01-08 rat
S O Ogren, I Misan. Animal models for studying serotonin (5-HT) receptor subtypes: relationship to 5-HT system pathologies. Nuclear medicine and biology vol 25 issue 8 1999 9863561 The present study focused on the particular role of 5-HT1A receptor subtype in aversive learning, i.e., the passive avoidance (PA) task in the rat. 1999-03-23 2022-01-08 Not clear
A Menese. Physiological, pathophysiological and therapeutic roles of 5-HT systems in learning and memory. Reviews in the neurosciences vol 9 issue 4 1999 9886142 For instance, when pre- vs post-training administration of 5-HT1A agonist, 5-HT2 antagonists and 5-HT4 agonists have been compared contrasting findings were reported in aversive and appetitive learning tasks. 1999-03-23 2022-01-08 Not clear
I Misane, C Johansson, S O Ogre. Analysis of the 5-HT1A receptor involvement in passive avoidance in the rat. British journal of pharmacology vol 125 issue 3 1999 9806333 .7 These findings indicate that the deficit of passive avoidance retention induced by the 5-HT1A agonists is mainly a result of stimulation of postsynaptic 5-HT1A receptors but not 5-HT2A receptors. 1999-03-04 2022-01-08 Not clear
I Misane, C Johansson, S O Ogre. Analysis of the 5-HT1A receptor involvement in passive avoidance in the rat. British journal of pharmacology vol 125 issue 3 1999 9806333 Analysis of the 5-HT1A receptor involvement in passive avoidance in the rat. 1999-03-04 2022-01-08 Not clear
I Misane, C Johansson, S O Ogre. Analysis of the 5-HT1A receptor involvement in passive avoidance in the rat. British journal of pharmacology vol 125 issue 3 1999 9806333 The effects of the 5-HT2A/2C agonist DOB, the selective 5-HT1A agonist NDO 008 (3-dipropylamino-5-hydroxychroman), and the two enantiomers of the selective 5-HT1A agonist 8-OH-DPAT (R(+)-8-OH-DPAT and S(-)-8-OH-DPAT) were studied in a step-through passive avoidance (PA) test in the male rat. 1999-03-04 2022-01-08 Not clear
S Ramboz, R Oosting, D A Amara, H F Kung, P Blier, M Mendelsohn, J J Mann, D Brunner, R He. Serotonin receptor 1A knockout: an animal model of anxiety-related disorder. Proceedings of the National Academy of Sciences of the United States of America vol 95 issue 24 1998 9826725 In the present report, we demonstrate that mice without 5-HT1A receptors display decreased exploratory activity and increased fear of aversive environments (open or elevated spaces). 1998-12-28 2022-01-08 mouse
I Misane, H Razani, F H Wang, A Jansson, K Fuxe, S O Ogre. Intraventricular galanin modulates a 5-HT1A receptor-mediated behavioural response in the rat. The European journal of neuroscience vol 10 issue 4 1998 9749777 8-OH-DPAT given at a low dose 0.03 mg/kg, which presumably stimulates somatodendritic 5-HT1A autoreceptors in vivo, did not alter passive avoidance retention or induce any visually detectable signs of the 5-HT syndrome. 1998-10-22 2022-01-08 Not clear
I Misane, H Razani, F H Wang, A Jansson, K Fuxe, S O Ogre. Intraventricular galanin modulates a 5-HT1A receptor-mediated behavioural response in the rat. The European journal of neuroscience vol 10 issue 4 1998 9749777 to modify the impairment of passive avoidance retention induced by the selective 5-HT1A agonist 8-hydroxy-2-(di-n-propyloamino)tetralin (8-OH-DPAT) when injected prior to training. 1998-10-22 2022-01-08 Not clear
I Misane, H Razani, F H Wang, A Jansson, K Fuxe, S O Ogre. Intraventricular galanin modulates a 5-HT1A receptor-mediated behavioural response in the rat. The European journal of neuroscience vol 10 issue 4 1998 9749777 Furthermore, both the impairment of passive avoidance and the 5-HT syndrome were completely blocked by the 5-HT1A receptor antagonist WAY 100635 (0.1 mg/kg). 1998-10-22 2022-01-08 Not clear
M T Hsieh, C R Wu, C C Hsie. Ameliorating effect of p-hydroxybenzyl alcohol on cycloheximide-induced impairment of passive avoidance response in rats: interactions with compounds acting at 5-HT1A and 5-HT2 receptors. Pharmacology, biochemistry, and behavior vol 60 issue 2 1998 9632215 Ameliorating effect of p-hydroxybenzyl alcohol on cycloheximide-induced impairment of passive avoidance response in rats: interactions with compounds acting at 5-HT1A and 5-HT2 receptors. 1998-08-17 2022-01-08 rat
E P Prinssen, M S Kleven, W Koe. Effects of dopamine antagonists in a two-way active avoidance procedure in rats: interactions with 8-OH-DPAT, ritanserin, and prazosin. Psychopharmacology vol 128 issue 2 1997 8956380 The 5-HT1A agonist 8-OH-DPAT (0.16 mg/kg) significantly enhanced the inhibitory effects of both raclopride and haloperidol on the conditioned avoidance response and produced a small enhancement of the effects of haloperidol on escape failures. 1997-04-10 2022-01-07 rat
C L\\xc3\\xb3pez-Rubalcav. Pre- or postsynaptic activity of 5-HT1A compounds in mice depends on the anxiety paradigm. Pharmacology, biochemistry, and behavior vol 54 issue 4 1997 8853189 To this aim, the 5-HT1A ligands buspirone, ipsapirone, indorenate, and 8-OH-DPAT were tested in the burying behavior test and the avoidance exploratory behavior paradigm in control, pCPA-treated, and 5,7-DHT-lesioned mice, p-CPA and 5,7-DHT treatments did not modify the burying behavior per se, while 5-HT1A agonists produced a significant reduction in this behavior in both p-CPA- and 5,7,-DHT-lesioned animals. 1997-01-06 2022-01-07 mouse
C L\\xc3\\xb3pez-Rubalcav. Pre- or postsynaptic activity of 5-HT1A compounds in mice depends on the anxiety paradigm. Pharmacology, biochemistry, and behavior vol 54 issue 4 1997 8853189 The ICV injection of 5,7-DHT blocked such effect of the 5-HT1A compounds in the avoidance exploratory behavior test. 1997-01-06 2022-01-07 mouse
C L\\xc3\\xb3pez-Rubalcav. Pre- or postsynaptic activity of 5-HT1A compounds in mice depends on the anxiety paradigm. Pharmacology, biochemistry, and behavior vol 54 issue 4 1997 8853189 Data suggest that the effect of 5-HT1A compounds in the burying behavior test is mediated via the stimulation of postsynaptic receptors, while in the avoidance exploratory behavior paradigm these compounds act through the stimulation of the presynaptic site. 1997-01-06 2022-01-07 mouse
T Oyama, M Ueda, Y Kuraishi, A Akaike, M Sato. Dual effect of serotonin on formalin-induced nociception in the rat spinal cord. Neuroscience research vol 25 issue 2 1996 8829149 In the 5,7-DHT-treated rats, intrathecal administration of 1-(m-chlorophenyl)-biguanide, a selective 5-HT3 receptor agonist, facilitated the aversive responses in the second phase whereas that of 8-OH-DPAT, a selective 5-HT1A receptor agonist, suppressed them. 1996-12-13 2022-01-07 rat
S Hog. A review of the validity and variability of the elevated plus-maze as an animal model of anxiety. Pharmacology, biochemistry, and behavior vol 54 issue 1 1996 8728535 Animals that are habituated to gentle handling or tested in less aversive conditions (e.g., EPM with ledges) show reduced likelihood of anxiolytic responses with administration of 5-HT3 antagonists, 5-HT1A agonists, and benzodiazepines. 1996-10-23 2022-01-07 rat
C Torres, A Morales, A C\\xc3\\xa1ndido, A Maldonad. Differential effect of buspirone and diazepam on negative contrast in one-way avoidance learning. European journal of pharmacology vol 280 issue 3 1996 8566095 The main aim of the present work was to investigate the effect of buspirone, a 5-HT1A receptor agonist, on successive negative contrast in one-way avoidance learning. 1996-03-07 2022-01-07 rat
R L Nogueira, F G Graef. Role of 5-HT receptor subtypes in the modulation of dorsal periaqueductal gray generated aversion. Pharmacology, biochemistry, and behavior vol 52 issue 1 1996 7501649 To explore the role of 5-HT receptor subtypes in controlling aversion, we measured the effect of 5-HT1A and 5-HT2A/2C receptor agonists microinjected into the dorsal periaqueductal gray (DPAG) of rats on aversive behavior induced by electrical stimulation of the same brain area. 1996-01-16 2022-01-07 rat
R L Nogueira, F G Graef. Role of 5-HT receptor subtypes in the modulation of dorsal periaqueductal gray generated aversion. Pharmacology, biochemistry, and behavior vol 52 issue 1 1996 7501649 The 5-HT1A agonists 8-OH-DPAT (4-16 nmol) and BAY-R-1531 (4-16 nmol) raised the threshold of aversive electrical stimulation in a dose-dependent way. 1996-01-16 2022-01-07 rat
Y Maeda, K Yamada, T Hasegawa, T Nabeshim. Neuronal mechanism of the inhibitory effect of calcitonin on N-methyl-D-aspartate-induced aversive behavior. European journal of pharmacology vol 275 issue 2 1995 7796851 These results suggest that beta-adrenoceptor, 5-HT1A, 5-HT3, GABAA and GABAB receptors, but not alpha-adrenoceptor, opioid nor 5-HT2A receptors, are involved in the inhibitory effect of calcitonin on intrathecally injected N-methyl-D-aspartate-induced aversive behavior in mice. 1995-08-03 2022-01-07 mouse
K Ensler, C N Ryan, J L Evende. Effects of repeated treatment with 5-HT1A agonists on active avoidance responding in the rat. Psychopharmacology vol 112 issue 1 1995 7871009 Buspirone, the 5-HT1A partial agonist/dopamine D2 antagonist, markedly decreased activity, and thus avoidance of the shocks, in a manner similar to the antipsychotic drug, haloperidol. 1995-03-29 2022-01-07 rat
K Ensler, C N Ryan, J L Evende. Effects of repeated treatment with 5-HT1A agonists on active avoidance responding in the rat. Psychopharmacology vol 112 issue 1 1995 7871009 Effects of repeated treatment with 5-HT1A agonists on active avoidance responding in the rat. 1995-03-29 2022-01-07 rat
K Ensler, C N Ryan, J L Evende. Effects of repeated treatment with 5-HT1A agonists on active avoidance responding in the rat. Psychopharmacology vol 112 issue 1 1995 7871009 Previously it has been found that the prototypical 5-HT1A receptor agonist, 8-OH-DPAT, increases avoidance, apparently by increasing general activity, after repeated administration but not on acute administration. 1995-03-29 2022-01-07 rat
D M Jackson, A Bengtsson, C Johansson, L Cortizo, S B Ros. Development of tolerance to 8-OH-DPAT induced blockade of acquisition of a passive avoidance response. Neuropharmacology vol 33 issue 8 1995 7845547 We examined the effects of manipulating 5-HT1A receptors on the performance of a passive avoidance task in rats. 1995-03-06 2022-01-07 rat
D M Jackson, A Bengtsson, C Johansson, L Cortizo, S B Ros. Development of tolerance to 8-OH-DPAT induced blockade of acquisition of a passive avoidance response. Neuropharmacology vol 33 issue 8 1995 7845547 The 5-HT1A antagonist (S)-UH-301 [(S)-5-fluoro-8-hydroxy-2-(dipropylamino)tetralin] was without effect on avoidance performance but antagonized the effect of 8-OH-DPAT. 1995-03-06 2022-01-07 rat
J L Evende. Effects of 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) after repeated administration on a conditioned avoidance response (CAR) in the rat. Psychopharmacology vol 109 issue 1-2 1995 1365647 8-OH-DPAT, a selective 5-HT1A agonist, has variously been found to impair, have no effect on or enhance the conditioned avoidance response (CAR). 1995-02-23 2022-01-07 human
A A Alhaider, A M Ageel, O T Ginaw. The quipazine- and TFMPP-increased conditioned avoidance response in rats: role of 5HT1C/5-HT2 receptors. Neuropharmacology vol 32 issue 12 1994 8152532 The 5-HT1A agonist, buspirone, significantly decreased acquisition of conditioned avoidance. 1994-05-10 2022-01-07 rat
F S Guimar\\xc3\\xa3es, E A Del Bel, C M Padovan, S M Netto, R T de Almeid. Hippocampal 5-HT receptors and consolidation of stressful memories. Behavioural brain research vol 58 issue 1-2 1994 8136041 These results are compatible with the idea that postsynaptic 5-HT1A receptors located in the hippocampus participate in the development of tolerance to aversive events. 1994-04-25 2022-01-07 rat
F S Guimar\\xc3\\xa3es, E A Del Bel, C M Padovan, S M Netto, R T de Almeid. Hippocampal 5-HT receptors and consolidation of stressful memories. Behavioural brain research vol 58 issue 1-2 1994 8136041 It has been suggested that postsynaptic 5-HT1A receptors in the hippocampus, innervated by 5-HT neurons localized in the median raphe nucleus, mediate adaptive or coping responses to aversive events and that dysfunction of this system is related to symptoms of depression. 1994-04-25 2022-01-07 rat
C M Padovan, F S Guimar\\xc3\\xa3e. Attenuation of behavioral consequences of immobilization stress by intra-hippocampal microinjection of zimelidine. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas vol 26 issue 10 1994 8312840 These results are compatible with the view that post-synaptic 5-HT1a receptors in the hippocampus mediate adaptive or coping responses to aversive events. 1994-03-24 2022-01-07 rat
S D Mendelson, D Quartermain, T Francisco, A Sheme. 5-HT1A receptor agonists induce anterograde amnesia in mice through a postsynaptic mechanism. European journal of pharmacology vol 236 issue 2 1993 8319749 The effect of the 5-HT1A receptor partial agonist tandospirone on memory was investigated in mice using a single trial, step-through passive avoidance task. 1993-08-05 2022-01-07 mouse
M Carli, E Tatarczynska, L Cervo, R Samani. Stimulation of hippocampal 5-HT1A receptors causes amnesia and anxiolytic-like but not antidepressant-like effects in the rat. European journal of pharmacology vol 234 issue 2-3 1993 8097721 The results suggest that stimulation of 5-HT1A receptors in the dorsal hippocampus impairs rats' performance in a passive avoidance task by interfering with memory processes or by attenuating the emotional impact of the shock through an anxiolytic action. 1993-06-03 2022-01-07 rat
N M Barnes, C H Cheng, B Costall, J Ge, M E Kelly, R J Naylo. Profiles of interaction of R(+)/S(-)-zacopride and anxiolytic agents in a mouse model. European journal of pharmacology vol 218 issue 1 1992 1356807 It is concluded that the reduction in aversive responding caused by pharmacological manipulation at the benzodiazepine, 5-HT receptor subtypes 5-HT1A, 5-HT1C/5-HT2 and 5-HT3 (but not at the cholecystokin CCKA or angiotensin receptors or inhibition of angiotensin converting enzyme) can be inhibited by R(+) and S(-)-zacopride. 1992-11-20 2022-01-07 Not clear
M Carli, S Tranchina, R Samani. 8-Hydroxy-2-(di-n-propylamino)tetralin, a 5-HT1A receptor agonist, impairs performance in a passive avoidance task. European journal of pharmacology vol 211 issue 2 1992 1535320 8-Hydroxy-2-(di-n-propylamino)tetralin, a 5-HT1A receptor agonist, impairs performance in a passive avoidance task. 1992-07-28 2022-01-09 rat
J F Deaki. Depression and 5HT. International clinical psychopharmacology vol 6 Suppl 3 issue 1992 1806632 Projections of the median raphe nucleus and associated 5HT1A receptors appear to mediate resilience to aversive events once they have occurred or if they persist. 1992-05-11 2022-01-07 Not clear
M L Wadenberg, S Ahleniu. Antipsychotic-like profile of combined treatment with raclopride and 8-OH-DPAT in the rat: enhancement of antipsychotic-like effects without catalepsy. Journal of neural transmission. General section vol 83 issue 1-2 1991 1673344 The administration of the 5-HT1A agonist 8-OH-DPAT, 0.1 mg kg-1 sc-20 min, produced a moderate suppression of conditioned avoidance behavior (60% of controls) in the rat. 1991-05-28 2022-01-07 rat
D Treit, K C Berridg. A comparison of benzodiazepine, serotonin, and dopamine agents in the taste-reactivity paradigm. Pharmacology, biochemistry, and behavior vol 37 issue 3 1991 1982355 The putative 5-HT1A agonists, buspirone and gepirone, had a general inhibitory action on both positive and aversive palatability reactions. 1991-05-23 2022-01-07 rat
F Jenck, C L Broekkamp, A M Van Delf. Opposite control mediated by central 5-HT1A and non-5-HT1A (5-HT1B or 5-HT1C) receptors on periaqueductal gray aversion. European journal of pharmacology vol 161 issue 2-3 1989 2524392 8-OH-DPAT, a selective 5-HT1A agonist, and mCPP, which has preferential affinity for 5-HT1B and 5-HT1C receptors, were studied for their effects on aversive brain stimulation in rats. 1989-07-07 2022-01-07 rat
M Abou-Gharbia, U R Patel, M B Webb, J A Moyer, T H Andree, E A Mut. Polycyclic aryl- and heteroarylpiperazinyl imides as 5-HT1A receptor ligands and potential anxiolytic agents: synthesis and structure-activity relationship studies. Journal of medicinal chemistry vol 31 issue 7 1988 2898533 Parameters measured included in vitro inhibition of D2 and 5-HT1A receptor binding, inhibition of apomorphine (APO) induced stereotyped and climbing behavior, and activity in blocking conditioned avoidance responding (CAR). 1988-08-05 2022-01-07 rat
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