All Relations between aversion and 5-ht receptor 1a

Publication Sentence Publish Date Extraction Date Species
Adriana Jesus Souza, Francisco S Guimarães, Felipe V Gome. Cannabidiol attenuates the expression of conditioned place aversion induced by naloxone-precipitated morphine withdrawal through the activation of 5-HT1A receptors. Behavioural brain research. 2023-05-20. PMID:37209879. cannabidiol attenuates the expression of conditioned place aversion induced by naloxone-precipitated morphine withdrawal through the activation of 5-ht1a receptors. 2023-05-20 2023-08-14 mouse
Adriana Jesus Souza, Francisco S Guimarães, Felipe V Gome. Cannabidiol attenuates the expression of conditioned place aversion induced by naloxone-precipitated morphine withdrawal through the activation of 5-HT1A receptors. Behavioural brain research. 2023-05-20. PMID:37209879. our findings suggest that cbd may reduce the expression of a previously established conditioned aversion induced by morphine withdrawal by a mechanism involving the activation of 5-ht1a receptors. 2023-05-20 2023-08-14 mouse
Majid Jafari-Sabet, Shiva Amiri, Helia Aghamiri, Navid Fatah. Cross state-dependent memory retrieval between cannabinoid CB1 and serotonergic 5-HT1A receptor agonists in the mouse dorsal hippocampus. Neurobiology of learning and memory. 2022-05-20. PMID:35595026. the present paper investigates the phenomenon called state-dependent memory (sdm) induced by acpa (a selective cannabinoid cb1 receptor agonist) and 8-oh-dpat (a nonselective 5-ht1a receptor agonist) with special focus on the role of the 5-ht1a receptor in the effects of both acpa and 8-oh-dpat sdm and cross state-dependent memory retrieval between acpa and 8-oh-dpat in a step-down inhibitory avoidance task. 2022-05-20 2023-08-13 mouse
Chloe U Wallis, Gemma J Cockcroft, Rudolf N Cardinal, Angela C Roberts, Hannah F Clark. Hippocampal Interaction With Area 25, but not Area 32, Regulates Marmoset Approach-Avoidance Behavior. Cerebral cortex (New York, N.Y. : 1991). vol 29. issue 11. 2020-10-20. PMID:30796800. simultaneous inactivation or 5-ht1a antagonism within area 25, but not area 32, abolished the reduced punishment avoidance seen after increasing ahipp glutamate. 2020-10-20 2023-08-13 monkey
Annina Huser, Melanie Eschment, Nazli Güllü, Katharina A N Collins, Kathrin Böpple, Lyubov Pankevych, Emilia Rolsing, Andreas S Thu. Anatomy and behavioral function of serotonin receptors in Drosophila melanogaster larvae. PloS one. vol 12. issue 8. 2017-10-10. PMID:28777821. our data suggest that 5-ht1a, 5-ht1b, and 5-ht7 are dispensable for larval naïve olfactory and gustatory choice behaviors as well as for appetitive and aversive associative olfactory learning and memory. 2017-10-10 2023-08-13 drosophila_melanogaster
Ailton Spiacci, Roger Luis Henschel Pobbe, Melina Matthiesen, Helio Zangross. 5-HT1A receptors of the rat dorsal raphe lateral wings and dorsomedial subnuclei differentially control anxiety- and panic-related defensive responses. Neuropharmacology. vol 107. 2017-06-19. PMID:26145183. intra-dmdr injection of either the excitatory amino acid kainic acid or the 5-ht1a receptor antagonist way-100635 facilitated inhibitory avoidance acquisition, suggesting an anxiogenic effect, and inhibited escape expression, a panicolytic-like effect. 2017-06-19 2023-08-13 rat
Sudhakar Selvaraj, Elias Mouchlianitis, Paul Faulkner, Federico Turkheimer, Philip J Cowen, Jonathan P Roiser, Oliver Howe. Presynaptic Serotoninergic Regulation of Emotional Processing: A Multimodal Brain Imaging Study. Biological psychiatry. vol 78. issue 8. 2016-06-09. PMID:24882568. however, it is unknown whether 5-ht1a receptor availability is linked specifically to the processing of aversive emotions in humans or whether it modulates connectivity in brain networks involved in emotion processing. 2016-06-09 2023-08-13 Not clear
Sudhakar Selvaraj, Elias Mouchlianitis, Paul Faulkner, Federico Turkheimer, Philip J Cowen, Jonathan P Roiser, Oliver Howe. Presynaptic Serotoninergic Regulation of Emotional Processing: A Multimodal Brain Imaging Study. Biological psychiatry. vol 78. issue 8. 2016-06-09. PMID:24882568. to answer this question, we investigated the relationship between drn 5-ht1a receptor availability and amygdala reactivity to aversive emotion and functional connectivity within the amygdala-cortical network. 2016-06-09 2023-08-13 Not clear
Valeria Pittalà, Maria A Siracusa, Loredana Salerno, Giuseppe Romeo, Maria N Modica, Nather Madjid, Sven Ove Ogre. Analysis of mechanisms for memory enhancement using novel and potent 5-HT1A receptor ligands. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 25. issue 8. 2016-05-06. PMID:25963581. in light of the involvement of serotonergic 5-ht1a receptors in the mediation of the memory of aversive events, the potent and selective 5-ht1a receptor antagonists, mc18 fumarate and vp08/34 fumarate, were tested in the passive avoidance task (pa), a rodent model of instrumental conditioning. 2016-05-06 2023-08-13 Not clear
Marcel P Rangel, Hélio Zangrossi, Camila M Roncon, Frederico G Graeff, Elisabeth A Aud. Interaction between μ-opioid and 5-HT1A receptors in the regulation of panic-related defensive responses in the rat dorsal periaqueductal grey. Journal of psychopharmacology (Oxford, England). vol 28. issue 12. 2015-12-23. PMID:25315826. therefore, regardless of the aversive nature of the stimulus, μ-opioid and 5-ht1a receptors cooperatively act to regulate escape behaviour. 2015-12-23 2023-08-13 rat
Hélio Zangrossi, Frederico G Graef. Serotonin in anxiety and panic: contributions of the elevated T-maze. Neuroscience and biobehavioral reviews. vol 46 Pt 3. 2015-07-17. PMID:24657635. the evidence so far reported with the etm supports the above hypothesis and indicates that: (1) whereas 5-ht neurons located at the dorsal raphe nucleus are involved in the regulation of both inhibitory avoidance and escape, those of the median raphe nucleus are primarily implicated in the former task; (2) facilitation of 5-ht1a- and 5-ht2a-mediated neurotransmission in the dorsal periaqueductal gray (dpag) is likely to mediate the panicolytic drug action; (3) stimulation of 5-ht2c receptors in the basolateral amygdala increases anxiety and is implicated in the anxiogenesis caused by short-term administration of antidepressant drugs, and (4) 5-ht1a and the μ-opioid receptors work together in the dpag to modulate escape or panic attacks. 2015-07-17 2023-08-12 rat
Juliana O G Nascimento, Letícia Sumiko Kikuchi, Valquíria Camin de Bortoli, Hélio Zangrossi, Milena B Vian. Dorsomedial hypothalamus serotonin 1A receptors mediate a panic-related response in the elevated T-maze. Brain research bulletin. vol 109. 2015-07-10. PMID:25290207. in this study we further explore the relationship of the dmh with defense by investigating the effects of 5-ht1a activation on escape behavior generated in male wistar rats by an ethologically based aversive stimuli, exposure to one of the open arms of the elevated t-maze (etm). 2015-07-10 2023-08-13 rat
Lauren R Bader, Joseph D Carboni, Cody A Burleson, Matthew A Coope. 5-HT1A receptor activation reduces fear-related behavior following social defeat in Syrian hamsters. Pharmacology, biochemistry, and behavior. vol 122. 2015-01-26. PMID:24726709. we hypothesized that pharmacological activation of 5-ht1a receptors prior to social defeat would reduce avoidance of familiar opponents and impair arc expression in the basolateral amygdala (bla), but not alter anxiety-like behavior. 2015-01-26 2023-08-13 Not clear
M Joelle Dill, Janice Shaw, Jeff Cramer, Dana K Sindela. 5-HT1A receptor antagonists reduce food intake and body weight by reducing total meals with no conditioned taste aversion. Pharmacology, biochemistry, and behavior. vol 112. 2014-07-16. PMID:24064183. 5-ht1a receptor antagonists reduce food intake and body weight by reducing total meals with no conditioned taste aversion. 2014-07-16 2023-08-12 mouse
M Joelle Dill, Janice Shaw, Jeff Cramer, Dana K Sindela. 5-HT1A receptor antagonists reduce food intake and body weight by reducing total meals with no conditioned taste aversion. Pharmacology, biochemistry, and behavior. vol 112. 2014-07-16. PMID:24064183. these results indicate that 5-ht1a receptor antagonist suppresses feeding, specifically by decreasing the number of meals, and induce weight loss without an aversive side effect. 2014-07-16 2023-08-12 mouse
Taku Yamaguchi, Aki Tsujimatsu, Haruko Kumamoto, Takeshi Izumi, Yu Ohmura, Takayuki Yoshida, Mitsuhiro Yoshiok. Anxiolytic effects of yokukansan, a traditional Japanese medicine, via serotonin 5-HT1A receptors on anxiety-related behaviors in rats experienced aversive stress. Journal of ethnopharmacology. vol 143. issue 2. 2013-01-29. PMID:22819689. anxiolytic effects of yokukansan, a traditional japanese medicine, via serotonin 5-ht1a receptors on anxiety-related behaviors in rats experienced aversive stress. 2013-01-29 2023-08-12 rat
Tomoko Horisawa, Tadashi Ishibashi, Hiroyuki Nishikawa, Takeshi Enomoto, Satoko Toma, Takeo Ishiyama, Mutsuo Taij. The effects of selective antagonists of serotonin 5-HT7 and 5-HT1A receptors on MK-801-induced impairment of learning and memory in the passive avoidance and Morris water maze tests in rats: mechanistic implications for the beneficial effects of the novel atypical antipsychotic lurasidone. Behavioural brain research. vol 220. issue 1. 2011-07-15. PMID:21277905. the effects of selective antagonists of serotonin 5-ht7 and 5-ht1a receptors on mk-801-induced impairment of learning and memory in the passive avoidance and morris water maze tests in rats: mechanistic implications for the beneficial effects of the novel atypical antipsychotic lurasidone. 2011-07-15 2023-08-12 rat
M Marziniak, R Mössner, C Kienzler, P Riederer, K-P Lesch, C Somme. Functional polymorphisms of the 5-HT1A and 5-HT1B receptor are associated with clinical symptoms in migraineurs. Journal of neural transmission (Vienna, Austria : 1996). vol 114. issue 9. 2009-11-27. PMID:17417740. we report a positive association of the gg genotype of the 5-ht1a promoter polymorphism with avoidance of physical activity during a migraine attack in comparison to the cc genotype (p = 0.008). 2009-11-27 2023-08-12 human
Vanessa de Paula Soares, Hélio Zangross. Stimulation of 5-HT1A or 5-HT2A receptors in the ventrolateral periaqueductal gray causes anxiolytic-, but not panicolytic-like effect in rats. Behavioural brain research. vol 197. issue 1. 2009-04-10. PMID:18801389. in the present study we evaluated whether the activation of 5-ht1a and 5-ht2a/2c receptors in the ventrolateral column of the periaqueductal gray (vlpag) causes differential effects on an anxiety- and a panic-related defensive behavior, respectively, inhibitory avoidance and escape, in male wistar rats submitted to the elevated t-maze. 2009-04-10 2023-08-12 rat
Milena de Barros Viana, Hélio Zangrossi, Gustavo Massaro Onusi. 5-HT1A receptors of the lateral septum regulate inhibitory avoidance but not escape behavior in rats. Pharmacology, biochemistry, and behavior. vol 89. issue 3. 2008-05-20. PMID:18282594. 5-ht1a receptors of the lateral septum regulate inhibitory avoidance but not escape behavior in rats. 2008-05-20 2023-08-12 rat