| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lisa R Taxier, Meghan E Flanigan, Harold L Haun, Thomas L Kas. Retrieval of an ethanol-conditioned taste aversion promotes GABAergic plasticity in the insular cortex. bioRxiv : the preprint server for biology. 2024-04-02. PMID:38562680. |
retrieval of an ethanol-conditioned taste aversion promotes gabaergic plasticity in the insular cortex. |
2024-04-02 |
2024-04-04 |
mouse |
| Lisa R Taxier, Meghan E Flanigan, Harold L Haun, Thomas L Kas. Retrieval of an ethanol-conditioned taste aversion promotes GABAergic plasticity in the insular cortex. bioRxiv : the preprint server for biology. 2024-04-02. PMID:38562680. |
plasticity in cells projecting from the insular cortex (ic) to the basolateral amygdala (bla) is critical for taste aversion learning and retrieval, suggesting this circuit's potential involvement in modulating the aversive properties of ethanol. |
2024-04-02 |
2024-04-04 |
mouse |
| Thang Le, Takeyuki Oba, Luke Couch, Lauren McInerney, Chiang-Shan L. Deficits in proactive avoidance and neural responses to drinking motives in problem drinkers. Research square. 2024-02-26. PMID:38405986. |
imaging findings in problem drinkers showed that negative emotions as a drinking motive predicted attenuated right insula activation during proactive avoidance. |
2024-02-26 |
2024-02-28 |
Not clear |
| María G Briones-Vidal, Salma E Reyes-García, Martha L Escoba. NEUROTROPHIN-3 INTO THE INSULAR CORTEX STRENGTHENS CONDITIONED TASTE AVERSION MEMORY. Behavioural brain research. 2024-01-11. PMID:38211776. |
neurotrophin-3 into the insular cortex strengthens conditioned taste aversion memory. |
2024-01-11 |
2024-01-14 |
rat |
| María G Briones-Vidal, Salma E Reyes-García, Martha L Escoba. NEUROTROPHIN-3 INTO THE INSULAR CORTEX STRENGTHENS CONDITIONED TASTE AVERSION MEMORY. Behavioural brain research. 2024-01-11. PMID:38211776. |
the neurotrophin 3 (nt-3), a member of the neurotrophin family, and its high affinity receptor trkc, are widely expressed in the insular cortex (ic), a region with a critical role in the consolidation of the conditioned taste aversion (cta) paradigm, in which an animal associates a novel taste with nausea. |
2024-01-11 |
2024-01-14 |
rat |
| Juliana Belo Diniz, Paulo Rodrigo Bazán, Carlos Alberto de Bragança Pereira, Erlandson Ferreira Saraiva, Paula Roberta Camargo Ramos, Amanda Ribeiro de Oliveira, Adriano Edgar Reimer, Marcelo Queiroz Hoexter, Euripedes Constantino Miguel, Roseli Gedanke Shavitt, Marcelo Camargo Batistuzz. Brain activation during fear extinction recall in unmedicated patients with obsessive-compulsive disorder. Psychiatry research. Neuroimaging. vol 336. 2023-11-01. PMID:37913655. |
during conditioning, groups differed regarding the skin conductance reactivity to the aversive stimulus (shock) and regarding the activation of the right opercular cortex, insular cortex, putamen, and lingual gyrus in response to conditioned stimuli. |
2023-11-01 |
2023-11-08 |
human |
| Beatriz Gutiérrez-Vera, Salma E Reyes-García, Martha L Escoba. Brief environmental enrichment elicits metaplasticity on the insular cortex in vivo and reduces the strength of conditioned taste aversion. Neurobiology of learning and memory. 2023-10-07. PMID:37805119. |
brief environmental enrichment elicits metaplasticity on the insular cortex in vivo and reduces the strength of conditioned taste aversion. |
2023-10-07 |
2023-10-15 |
rat |
| Beatriz Gutiérrez-Vera, Salma E Reyes-García, Martha L Escoba. Brief environmental enrichment elicits metaplasticity on the insular cortex in vivo and reduces the strength of conditioned taste aversion. Neurobiology of learning and memory. 2023-10-07. PMID:37805119. |
our previous studies have shown that prior training in conditioned taste aversion (cta) prevents the subsequent induction of ltp in the projection from the basolateral nucleus of the amygdala (bla) to the insular cortex (ic) in vivo. |
2023-10-07 |
2023-10-15 |
rat |
| Beatriz Gutiérrez-Vera, Salma E Reyes-García, Martha L Escoba. Brief environmental enrichment elicits metaplasticity on the insular cortex in vivo and reduces the strength of conditioned taste aversion. Neurobiology of learning and memory. 2023-10-07. PMID:37805119. |
our results demonstrate that a seven-day exposure to an enriched environment attenuates the aversive response to a strong cta and allows the induction but not the maintenance of ltp in the insular cortex. |
2023-10-07 |
2023-10-15 |
rat |
| Siqi Xiao, Haiju Sun, Yichen Zhu, Zui Shen, Xixiao Zhu, Ping-An Yao, Yifang Wang, Chi Zhang, Wei Yu, Zemin Wu, Jing Sun, Chi Xu, Junying Du, Xiaofen He, Jianqiao Fang, Xiaomei Sha. Electroacupuncture alleviates the relapse of pain-related aversive memory by activating KOR and inhibiting GABAergic neurons in the insular cortex. Cerebral cortex (New York, N.Y. : 1991). 2023-09-07. PMID:37679857. |
the insular cortex is a key region closely related to aversive behaviors. |
2023-09-07 |
2023-10-07 |
mouse |
| Yu Chen, Chiang-Shan R L. Appetitive and aversive cue reactivities differentiate neural subtypes of alcohol drinkers. Addiction neuroscience. vol 7. 2023-07-24. PMID:37483686. |
the appetitive circuit involved medial cortical regions and the ventral striatum, and the aversive circuit involved the insula, caudate and mid-cingulate cortex. |
2023-07-24 |
2023-08-14 |
Not clear |
| A Mukherjee, M S Paladino, S L McSain, E A Gilles-Thomas, D D Lichte, R D Camadine, S Willock, K V Sontate, S C Honeycutt, G C Lone. Escalation of alcohol intake is associated with regionally decreased insular cortex activity but not associated with changes in taste quality. Alcoholism, clinical and experimental research. 2023-03-21. PMID:36941800. |
intermittent etoh drinking may facilitate escalation in part by altering aversion-sensitive neural substrates, such as the insular cortex (ic), thus driving greater approach toward stimuli previously treated as aversive. |
2023-03-21 |
2023-08-14 |
Not clear |
| Han Li, Zheng Gan, Lirong Wang, Manfred Josef Oswald, Rohini Kune. Prolonged Suppression of Neuropathic Hypersensitivity upon Neurostimulation of the Posterior Insula in Mice. Cells. vol 11. issue 20. 2022-10-27. PMID:36291169. |
here, we developed an approach to perform repetitive transcranial direct current stimulation of the posterior insula (pi tdcs) and studied its impact on sensory and aversive components of neuropathic pain and pain-related anxiety and the underlying neural circuitry in mice using behavioral methods, pharmacological interventions and the expression of the activity-induced gene product, fos. |
2022-10-27 |
2023-08-14 |
mouse |
| Stephanie M Staszko, John D Boughter, Max L Fletche. The impact of familiarity on cortical taste coding. Current biology : CB. 2022-10-19. PMID:36261035. |
the role of the gustatory region of the insular cortex in mediating associative taste learning, such as conditioned taste aversion, has been well studied. |
2022-10-19 |
2023-08-14 |
mouse |
| Lindsey Marwood, Toby Wise, Jess Kerr-Gaffney, Rebecca Strawbridge, Steve C R Williams, Anthony J Cleare, Adam Perkin. Brain activity during pursuit and goal-conflict threat avoidance in major depressive disorder. Personality neuroscience. vol 5. 2022-09-15. PMID:36105154. |
anticipation of aversive stimuli was associated with significant activation in the dorsal anterior cingulate cortex, superior frontal gyrus, and striatum, while active avoidance of aversive stimuli was associated with activity in dorsal anterior cingulate cortex, insula, and prefrontal cortex. |
2022-09-15 |
2023-08-14 |
human |
| Ruth Steiger, Noora Tuovinen, Agne Adukauskaite, Thomas Senoner, Philipp Spitaler, Valentin Bilgeri, Agnieszka Dabkowska-Mika, Christian Siedentopf, Axel Bauer, Elke Ruth Gizewski, Alex Hofer, Fabian Barbieri, Wolfgang Dicht. Limbic Responses to Aversive Visual Stimuli during the Acute and Recovery Phase of Takotsubo Syndrome. Journal of clinical medicine. vol 11. issue 16. 2022-08-26. PMID:36013130. |
in the acute phase, takotsubo syndrome patients showed a lower response in regions involved in affective and cognitive emotional processes (e.g., insula, thalamus, frontal cortex, inferior frontal gyrus) while viewing aversive versus positive pictures compared to healthy controls and patients presenting with myocardial infarction. |
2022-08-26 |
2023-08-14 |
Not clear |
| Sugai Liang, Yue Wu, Li Hanxiaoran, Andrew J Greenshaw, Tao L. Anhedonia in Depression and Schizophrenia: Brain Reward and Aversion Circuits. Neuropsychiatric disease and treatment. vol 18. 2022-07-15. PMID:35836582. |
blunted aversion processing in depression and relatively strong aversion in schizophrenia are primarily attributed to the dysfunction of the habenula, insula, amygdala, and anterior cingulate cortex. |
2022-07-15 |
2023-08-14 |
Not clear |
| Ziyu Hao, Huanhuan Li, Lisheng Ouyang, Fang Sun, Xiaotong Wen, Xiang Wan. Pain avoidance and functional connectivity between insula and amygdala identifies suicidal attempters in patients with major depressive disorder using machine learning. Psychophysiology. 2022-06-29. PMID:35767231. |
pain avoidance and functional connectivity between insula and amygdala identifies suicidal attempters in patients with major depressive disorder using machine learning. |
2022-06-29 |
2023-08-14 |
human |
| Salma E Reyes-García, Beatriz Gutiérrez-Vera, Martha L Escoba. Calcineurin requirement for in vivo insular cortex LTD and CTA-extinction. Neurobiology of learning and memory. 2022-06-09. PMID:35679998. |
indeed, studies of our research group have demonstrated that induction of ltd in the basolateral nucleus of the amygdala (bla) to the insular cortex (ic) pathway facilitates the extinction of conditioned taste aversion (cta), while the induction of ltp in this pathway slows it down. |
2022-06-09 |
2023-08-14 |
rat |
| Beatriz Gutiérrez-Vera, Alejandro Rivera-Olvera, Martha L Escoba. ENVIRONMENTAL ENRICHMENT ATTENUATES CONDITIONED TASTE AVERSION THROUGH THE RESTORATION OF BDNF LEVELS IN THE INSULAR CORTEX. Behavioural brain research. 2022-06-01. PMID:35644274. |
environmental enrichment attenuates conditioned taste aversion through the restoration of bdnf levels in the insular cortex. |
2022-06-01 |
2023-08-13 |
rat |