All Relations between conditioned response and microglial cell

Reference Sentence Publish Date Extraction Date Species
Rachel E James Bates, Eleanor Browne, Renee Schalks, Heather Jacobs, Li Tan, Puja Parekh, Roberta Magliozzi, Massimiliano Calabrese, Nicholas D Mazarakis, Richard Reynold. Lymphotoxin-alpha expression in the meninges causes lymphoid tissue formation and neurodegeneration. Brain : a journal of neurology vol issue 2022 35776111 conditioned medium from lt\xce\xb1 treated microglia was able to induce a reactive phenotype in astrocytes. 2022-07-01 2022-07-04 Not clear
Sara Merlo, Grazia Ilaria Caruso, Laura Bonfili, Simona Federica Spampinato, Giuseppe Costantino, Anna Maria Eleuteri, Maria Angela Sortin. Microglial polarization differentially affects neuronal vulnerability to the \\xce\\xb2-amyloid protein: modulation by melatonin. Biochemical pharmacology vol issue 2022 35750198 differentiated neuronal-like sh-sy5y cells were exposed to a\xce\xb242 (200 nm for 24 h) in basal medium or in the presence of conditioned medium (cm) collected from microglia exposed for different times to a\xce\xb242 alone or in combination with melco or melpost. 2022-06-24 2022-06-27 Not clear
Yuka Okusha, Benjamin J Lang, Ayesha Murshid, Thiago J Borges, Kristina M Holton, Joanne Clark-Matott, Sachin Doshi, Tsuneya Ikezu, Stuart K Calderwoo. Extracellular Hsp90\\xce\\xb1 stimulates a unique innate gene profile in microglial cells with simultaneous activation of Nrf2 and protection from oxidative stress. Cell stress & chaperones vol issue 2022 35689138 additionally, the toxicity of conditioned media obtained from microglia treated with fa\xce\xb2 was attenuated by addition of ehsp90\xce\xb1. 2022-06-10 2022-06-13 Not clear
Yuka Okusha, Benjamin J Lang, Ayesha Murshid, Thiago J Borges, Kristina M Holton, Joanne Clark-Matott, Sachin Doshi, Tsuneya Ikezu, Stuart K Calderwoo. Extracellular Hsp90\\xce\\xb1 stimulates a unique innate gene profile in microglial cells with simultaneous activation of Nrf2 and protection from oxidative stress. Cell stress & chaperones vol issue 2022 35689138 using a co-culture system of microglia and hippocampal neuronal cell line ht22 cells separated by a chamber insert, the neurotoxicity of medium conditioned by microglia treated with fa\xce\xb2 was reduced when ehsp90\xce\xb1 was also added. 2022-06-10 2022-06-13 Not clear
Angela Maria Casaril, Athanasios Katsalifis, Rolf M Schmidt, Carlos Bas-Ort. Activated glia cells cause bioenergetic impairment of neurons that can be rescued by knock-down of the mitochondrial calcium uniporter. Biochemical and biophysical research communications vol 608 issue 2022 35390671 rat primary cortical neurons were challenged with conditioned medium from mixed primary cultures of rat microglia and astrocytes that had been activated with lipopolysaccharide and atp. 2022-04-07 2022-04-14 Not clear
Guzal Khayrullina, Zaida A Alipio-Gloria, Marc-Olivier Deguise, Sabrina Gagnon, Lucia Chehade, Matthew Stinson, Natalya Belous, Elizabeth M Bergman, Fritz W Lischka, Jeremy Rotty, Clifton L Dalgard, Rashmi Kothary, Kristen A Johnson, Barrington G Burnet. Survival motor neuron protein deficiency alters microglia reactivity. Glia vol issue 2022 35373853 importantly, cell morphology and electrophysiological properties of motor neurons were altered when they were incubated with conditioned media from sma microglia. 2022-04-04 2022-04-14 Not clear
Ana Isabel S\\xc3\\xa1nchez-Castillo, M Rosario Sep\\xc3\\xbalveda, Jos\\xc3\\xa9 Luis Mar\\xc3\\xadn-Teva, Miguel A Cuadros, David Mart\\xc3\\xadn-Oliva, Elena Gonz\\xc3\\xa1lez-Rey, Mario Delgado, Veronika E Neubran. Switching Roles: Beneficial Effects of Adipose Tissue-Derived Mesenchymal Stem Cells on Microglia and Their Implication in Neurodegenerative Diseases. Biomolecules vol 12 issue 2 2022 35204722 in this review, we will discuss the application of adipose tissue-derived msc and their conditioned medium, including extracellular vesicles, in neurological disorders, their beneficial effect on microglia and the signaling pathways involved. 2022-03-30 2022-02-27 Not clear
Natalia Salvadores, Ines Moreno-Gonzalez, Nazaret Gamez, Gabriel Quiroz, Laura Vegas-Gomez, Marcela Escand\\xc3\\xb3n, Sebastian Jimenez, Javier Vitorica, Antonia Gutierrez, Claudio Soto, Felipe A Cour. A\\xce\\xb2 oligomers trigger necroptosis-mediated neurodegeneration via microglia activation in Alzheimer's disease. Acta neuropathologica communications vol 10 issue 1 2022 35264247 using an in vitro model, we show that conditioned medium from a\xce\xb2o-stimulated microglia elicited necroptosis in neurons through activation of tnf-\xce\xb1 signaling, triggering extensive neurodegeneration. 2022-03-10 2022-04-14 Not clear
Ana Isabel S\\xc3\\xa1nchez-Castillo, M Rosario Sep\\xc3\\xbalveda, Jos\\xc3\\xa9 Luis Mar\\xc3\\xadn-Teva, Miguel A Cuadros, David Mart\\xc3\\xadn-Oliva, Elena Gonz\\xc3\\xa1lez-Rey, Mario Delgado, Veronika E Neubran. Switching Roles: Beneficial Effects of Adipose Tissue-Derived Mesenchymal Stem Cells on Microglia and Their Implication in Neurodegenerative Diseases. Biomolecules vol 12 issue 2 2022 35204722 in this review, we will discuss the application of adipose tissue-derived msc and their conditioned medium, including extracellular vesicles, in neurological disorders, their beneficial effect on microglia and the signaling pathways involved. 2022-02-25 2022-02-27 Not clear
Bernarda Majc, Anamarija Habi\\xc4\\x8d, Metka Novak, Ana Rotter, Andrej Por\\xc4\\x8dnik, Jernej Mlakar, Vera \\xc5\\xbdupunski, Ur\\xc5\\xa1a Pe\\xc4\\x8dar Fonovi\\xc4\\x87, Damijan Knez, Nace Zidar, Stanislav Gobec, Janko Kos, Tamara Lah Turn\\xc5\\xa1ek, Anja Pi\\xc5\\xa1lar, Barbara Brezni. Upregulation of Cathepsin X in Glioblastoma: Interplay with \\xce\\xb3-Enolase and the Effects of Selective Cathepsin X Inhibitors. International journal of molecular sciences vol 23 issue 3 2022 35163706 selective cathepsin x inhibitors decreased the viability of patient-derived gbm cells as well as macrophages and microglia that were cultured in conditioned media of gbm cells. 2022-02-15 2022-02-17 Not clear
Sumana Ramarao, Yi Pang, Kathleen Carter, Abhay Bhat. Azithromycin Protects Oligodendrocyte Progenitor Cells against Lipopolysaccharide-Activated Microglia-Induced Damage. Developmental neuroscience vol 44 issue 1 2022 34571509 microglia conditioned medium (mcm) was used to determine inflammatory cytokines by enzyme-linked immunosorbent assay or subsequent treatment of opcs. 2022-02-11 2022-02-13 Not clear
Xiao-Dong Chen, Jin Zhao, Xiao Yang, Bo-Wei Zhou, Zhengzheng Yan, Wei-Feng Liu, Cai Li, Ke-Xuan Li. Gut-Derived Exosomes Mediate Memory Impairment After Intestinal Ischemia/Reperfusion via Activating Microglia. Molecular neurobiology vol 58 issue 10 2021 34189701 primary microglia were cocultured with intestinal exosomes; ht-22 cells were treated with intestinal exosomes or microglia conditioned media. 2022-02-03 2022-01-13 Not clear
Salvatore J Coniglio, Jeffrey E Segal. Microglial-stimulation of glioma invasion involves the EGFR ligand amphiregulin. PloS one vol 16 issue 11 2021 34843542 we assayed cdna and protein from microglia treated with conditioned media from the murine glioma cell line gl261, and discovered that several egfr ligands including amphiregulin (areg) are strongly upregulated. 2021-12-03 2022-01-13 Not clear
Ke-Bing Chen, Min-Min Chang, Sheng-Li Wang, Yong-Xin Li, Yi-Xi Wang, Zhi-Guang Xu, Hong Wang, Bing-Cheng Zhao, Wei-Ying M. High mobility group box-1 serves a pathogenic role in spinal cord injury via the promotion of pro-inflammatory cytokines. Journal of leukocyte biology vol 110 issue 6 2021 34402106 in addition, the injured neuron-derived conditioned medium increased tnf-\xce\xb1 secretion and the nf-\xce\xbab pathway in the bv2 microglia cell line via hmgb1. 2021-11-30 2022-01-13 Not clear
Saumya Mishra, Charul Rajput, Mahendra Pratap Sing. Cypermethrin Induces the Activation of Rat Primary Microglia and Expression of Inflammatory Proteins. Journal of molecular neuroscience : MN vol 71 issue 6 2021 33230707 cypermethrin-treated microglia conditioned media and cells were collected to measure the expression and release of inflammatory proteins. 2021-11-23 2022-01-13 Not clear
Saumya Mishra, Charul Rajput, Mahendra Pratap Sing. Cypermethrin Induces the Activation of Rat Primary Microglia and Expression of Inflammatory Proteins. Journal of molecular neuroscience : MN vol 71 issue 6 2021 33230707 cypermethrin augmented the protein kinase c-\xce\xb4 (pkc-\xce\xb4), inducible nitric oxide synthase (inos), phosphorylated mitogen-activated protein kinase (mapk) p38 and p42/44, matrix metalloproteinase (mmp)-3, and mmp-9 levels in the cell lysate and tumour necrosis factor-\xce\xb1 (tnf-\xce\xb1) and interleukin-1\xce\xb2 (il-1\xce\xb2) levels in the microglia conditioned media. 2021-11-23 2022-01-13 Not clear
Saumya Mishra, Charul Rajput, Mahendra Pratap Sing. Cypermethrin Induces the Activation of Rat Primary Microglia and Expression of Inflammatory Proteins. Journal of molecular neuroscience : MN vol 71 issue 6 2021 33230707 pre-treatment with minocycline, a microglial activation inhibitor or rottlerin, a pkc-\xce\xb4 inhibitor, notably reduced the release of tnf-\xce\xb1 in the conditioned media and expression of inos protein in the microglia. 2021-11-23 2022-01-13 Not clear
Saumya Mishra, Charul Rajput, Mahendra Pratap Sing. Cypermethrin Induces the Activation of Rat Primary Microglia and Expression of Inflammatory Proteins. Journal of molecular neuroscience : MN vol 71 issue 6 2021 33230707 while cypermethrin-treated conditioned media induced the toxicity in the rat primary neurons, minocycline or rottlerin reduced the cypermethrin treated microglia conditioned media-induced toxicity. 2021-11-23 2022-01-13 Not clear
Zhi-Bin Ding, Qing-Xian Han, Qing Wang, Li-Juan Song, Guo-Guo Chu, Min-Fang Guo, Zhi Chai, Jie-Zhong Yu, Bao-Guo Xiao, Xin-Yi Li, Cun-Gen M. Fasudil enhances the phagocytosis of myelin debris and the expression of neurotrophic factors in cuprizone-induced demyelinating mice. Neuroscience letters vol 753 issue 2021 33838256 in vitro, microglia with phagocytic debris exhibited enhanced expression of brain-derived neurotrophic factor (bdnf) and glial cell-derived neurotrophic factor (gdnf), and the conditioned medium promoted the maturation of oligodendrocyte precursor cells (opcs). 2021-11-22 2022-01-14 Not clear
Nuno L Soares, In\\xc3\\xaas Paiva, Joana Bravo, Cl\\xc3\\xa1udia S F Queiroga, Bernadete F Melo, S\\xc3\\xadlvia V Conde, Carlos C Rom\\xc3\\xa3o, Teresa Summavielle, Helena L A Vieir. Carbon Monoxide Modulation of Microglia-Neuron Communication: Anti-Neuroinflammatory and Neurotrophic Role. Molecular neurobiology vol issue 2021 34796462 in contrast, in the absence of inflammatory stimulus, conditioned media from co-treated microglia improved neuronal morphological complexity, which is an indirect manner of assessing neuronal function. 2021-11-19 2022-01-13 Not clear
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