All Relations between conditioned response and microglial cell

Reference Sentence Publish Date Extraction Date Species
Chao Gu, Fen Wang, Yu-Ting Zhang, Shi-Zhuang Wei, Jun-Yi Liu, Hong-Yang Sun, Guang-Hui Wang, Chun-Feng Li. Microglial MT1 activation inhibits LPS-induced neuroinflammation via regulation of metabolic reprogramming. Aging cell vol 20 issue 6 2021 33964119 Furthermore, in LPS-treated microglia, MT1 activation decreased the toxicity of conditioned media to the dopaminergic (DA) cell line MES23.5. 2021-12-28 2022-01-08 Not clear
Salvatore J Coniglio, Jeffrey E Segal. Microglial-stimulation of glioma invasion involves the EGFR ligand amphiregulin. PloS one vol 16 issue 11 2021 34843542 We assayed cDNA and protein from microglia treated with conditioned media from the murine glioma cell line GL261, and discovered that several EGFR ligands including amphiregulin (AREG) are strongly upregulated. 2021-12-21 2022-01-08 Not clear
Ke-Bing Chen, Min-Min Chang, Sheng-Li Wang, Yong-Xin Li, Yi-Xi Wang, Zhi-Guang Xu, Hong Wang, Bing-Cheng Zhao, Wei-Ying M. High mobility group box-1 serves a pathogenic role in spinal cord injury via the promotion of pro-inflammatory cytokines. Journal of leukocyte biology vol 110 issue 6 2021 34402106 In addition, the injured neuron-derived conditioned medium increased TNF-\xce\xb1 secretion and the NF-\xce\xbaB pathway in the BV2 microglia cell line via HMGB1. 2021-12-03 2022-01-08 Not clear
M P Flavin, G Zhao, L T H. Microglial tissue plasminogen activator (tPA) triggers neuronal apoptosis in vitro. Glia vol 29 issue 4 2000 10652444 We previously showed that conditioned medium (CM) harvested from peritoneal macrophages or from activated microglia triggered apoptosis in rat hippocampal neurons in culture. 2000-04-11 2022-01-08 Not clear
G M Jonakait, Y Wen, Y Wan, L N. Macrophage cell-conditioned medium promotes cholinergic differentiation of undifferentiated progenitors and synergizes with nerve growth factor action in the developing basal forebrain. Experimental neurology vol 161 issue 1 2000 10683294 Conditioned medium from stimulated microglia and from the monocyte/macrophage cell line (RAW 264.7; MC-CM) promotes the differentiation of cholinergic neurons from undifferentiated progenitors in the septal nuclei and adjacent basal forebrain (BF). 2000-03-23 2022-01-08 Not clear
M E Smith, M T Hoerne. Astrocytes modulate macrophage phagocytosis of myelin in vitro. Journal of neuroimmunology vol 102 issue 2 2000 10636484 While microglia were also stimulated by conditioned medium, adhesion to astrocytes or Matrigel induced a downregulation in phagocytic activity. 2000-01-27 2022-01-08 Not clear
S A South, G E Deibler, S F Tzeng, A Badache, M G Kirchner, N Muja, G H De Vrie. Myelin basic protein (MBP) and MBP peptides are mitogens for cultured astrocytes. Glia vol 29 issue 1 2000 10594925 The mitogenic effect of these individual peptides was potentiated by simultaneous treatment with microglia conditioned media (CM). 2000-01-18 2022-01-08 Not clear
R B Meeker, Y Azuma, D C Bragg, R V English, M Tompkin. Microglial proliferation in cortical neural cultures exposed to feline immunodeficiency virus. Journal of neuroimmunology vol 101 issue 1 1999 10580809 Conditioned medium from astrocytes or mixed neural cultures treated with feline immunodeficiency virus stimulated the proliferation of purified microglia. 1999-12-09 2022-01-08 Not clear
Y Persidsky, A Ghorpade, J Rasmussen, J Limoges, X J Liu, M Stins, M Fiala, D Way, K S Kim, M H Witte, M Weinand, L Carhart, H E Gendelma. Microglial and astrocyte chemokines regulate monocyte migration through the blood-brain barrier in human immunodeficiency virus-1 encephalitis. The American journal of pathology vol 155 issue 5 1999 10550317 Pure cultures of virus-infected and activated microglia or astrocytes exposed to microglial conditioned media produced significant quantities of beta-chemokines. 1999-11-30 2022-01-08 mouse
K A Young, W D Hirst, E Solito, G P Wilki. De novo expression of lipocortin-1 in reactive microglia and astrocytes in kainic acid lesioned rat cerebellum. Glia vol 26 issue 4 1999 10383052 LC-1 was detected in microglial but not astrocytic, conditioned media, confirming the in vivo observations that activated microglia may secrete LC-1. 1999-09-09 2022-01-08 Not clear
P J Kingham, M L Cuzner, J M Pococ. Apoptotic pathways mobilized in microglia and neurones as a consequence of chromogranin A-induced microglial activation. Journal of neurochemistry vol 73 issue 2 1999 10428049 Conditioned medium from activated microglia kills cerebellar granule cells by inducing caspase-3-dependent neuronal apoptosis. 1999-08-13 2022-01-08 Not clear
M P Flavin, L T H. Propentofylline protects neurons in culture from death triggered by macrophage or microglial secretory products. Journal of neuroscience research vol 56 issue 1 1999 10213475 We recently demonstrated that conditioned medium (CM) from peritoneal macrophages or activated microglia triggers a predominantly apoptotic death in hippocampal neurons in culture. 1999-06-07 2022-01-08 Not clear
R Zietlow, S B Dunnett, J W Fawcet. The effect of microglia on embryonic dopaminergic neuronal survival in vitro: diffusible signals from neurons and glia change microglia from neurotoxic to neuroprotective. The European journal of neuroscience vol 11 issue 5 1999 10215919 Conditioned medium from 7-day-old microglia was found to decrease the number of dopamine neurons surviving in primary culture, but activation of the microglia with N-formyl-methionyl-leucyl-phenylalanine (FMLP) or Zymosan A did not increase the toxicity of the conditioned medium. 1999-05-26 2022-01-08 Not clear
R Zietlow, S B Dunnett, J W Fawcet. The effect of microglia on embryonic dopaminergic neuronal survival in vitro: diffusible signals from neurons and glia change microglia from neurotoxic to neuroprotective. The European journal of neuroscience vol 11 issue 5 1999 10215919 The change in microglial effect from toxic to protective was caused by soluble molecules secreted by cells in the neuronal cultures, as conditioned medium derived from microglia-neuronal cocultures also had a dopaminergic neuron survival effect, indicating that microglia in cocultures behave differently from microglia removed from neuronal and glial influence. 1999-05-26 2022-01-08 Not clear
S Kyrkanides, J A Olschowka, J P Williams, J T Hansen, M K O'Banio. TNF alpha and IL-1beta mediate intercellular adhesion molecule-1 induction via microglia-astrocyte interaction in CNS radiation injury. Journal of neuroimmunology vol 95 issue 1-2 1999 10229119 However, exposure of astrocytes to conditioned medium collected from irradiated microglia resulted in ICAM-1 induction, which was abrogated when the conditioned medium was pre-incubated with neutralizing antibodies raised against murine TNF alpha and IL-1beta. 1999-05-17 2022-01-08 Not clear
C K Combs, D E Johnson, S B Cannady, T M Lehman, G E Landret. Identification of microglial signal transduction pathways mediating a neurotoxic response to amyloidogenic fragments of beta-amyloid and prion proteins. The Journal of neuroscience : the official journal of the Society for Neuroscience vol 19 issue 3 1999 9920656 We have demonstrated in a tissue culture model that conditioned media from beta-amyloid- and prion-stimulated microglia or from THP-1 monocytes are neurotoxic to mouse cortical neurons. 1999-02-25 2022-01-08 Not clear
S Sudo, J Tanaka, K Toku, J Desaki, S Matsuda, T Arai, M Sakanaka, N Maed. Neurons induce the activation of microglial cells in vitro. Experimental neurology vol 154 issue 2 1999 9878185 Medium conditioned by neurons significantly enhanced O2- generation by microglia, but microglial cells in contact with or in close apposition to cocultured neurons were much more intensely activated than those remote from the neurons. 1999-02-04 2022-01-08 Not clear
L Yang, J Tanaka, B Zhang, M Sakanaka, N Maed. Astrocytes modulate nitric oxide production by microglial cells through secretion of serine and glycine. Biochemical and biophysical research communications vol 251 issue 1 1998 9790946 Conditioned media obtained from microglia culture and neuron-microglia coculture contained less than 10 microM of Ser and Gly, while media from astrocyte culture and astrocyte-microglia coculture contained 33-41 microM Ser and 20-26 microM Gly. 1998-11-23 2022-01-08 Not clear
D R Brown, B Schmidt, H A Kretzschma. A prion protein fragment primes type 1 astrocytes to proliferation signals from microglia. Neurobiology of disease vol 4 issue 6 1998 9666480 Using conditioned medium from microglia we have shown that PrPc-expressing astrocytes proliferate in response to factors released by microglia stimulated by granulocyte/macrophage colony-stimulating factor. 1998-09-21 2022-01-08 Not clear
G W Perry, R W Kean. Modulation of microglial form and immune function by factors released from goldfish optic nerves. The International journal of neuroscience vol 91 issue 1-2 1997 9394221 To begin to investigate their role, microglia purified from mouse brain were grown in media conditioned (CM) by goldfish optic nerve (GFON), optic tectum (GFOT), vagal lobe, telencephalon and cerebellum, and medium conditioned by rat optic nerves (RON). 1997-12-29 2022-01-08 Not clear
G W Perry, R W Kean. Modulation of microglial form and immune function by factors released from goldfish optic nerves. The International journal of neuroscience vol 91 issue 1-2 1997 9394221 Microglia maintained in GFON- or GFOT-CM assumed an ameboid morphology, whereas microglia grown in media conditioned by the other neural tissues produced long, crenellated processes that resembled the ramified microglial form. 1997-12-29 2022-01-08 Not clear
Y Sugita, S P Becerra, G J Chader, J P Schwart. Pigment epithelium-derived factor (PEDF) has direct effects on the metabolism and proliferation of microglia and indirect effects on astrocytes. Journal of neuroscience research vol 49 issue 6 1997 9335258 Proliferation of isolated astrocytes was also blocked by conditioned medium from microglia treated with PEDF (PMCM). 1997-11-05 2022-01-08 Not clear
M P Flavin, K Coughlin, L T H. Soluble macrophage factors trigger apoptosis in cultured hippocampal neurons. Neuroscience vol 80 issue 2 1997 9284347 Conditioned medium from stimulated microglia showed a similar pattern of injury. 1997-10-17 2022-01-08 Not clear
J Frackowiak, B Mazur-Kolecka, R T Carroll, A Chauhan, H M Wisniewsk. Factors secreted by activated microglia and monocytes reduce amyloidogenesis in vascular smooth muscle cells. Neuroreport vol 8 issue 9-10 1997 9243622 We now show that accumulation of "A beta" deposits in this model can be significantly reduced by culture in conditioned media from microglia and monocytes. 1997-10-07 2022-01-08 Not clear
H Wilms, D Hartmann, J Siever. Ramification of microglia, monocytes and macrophages in vitro: influences of various epithelial and mesenchymal cells and their conditioned media. Cell and tissue research vol 287 issue 3 1997 9023076 Ramification of microglia, monocytes and macrophages in vitro: influences of various epithelial and mesenchymal cells and their conditioned media. 1997-04-10 2022-01-07 Not clear
G M Jonakait, M B Luskin, R Wei, X F Tian, L N. Conditioned medium from activated microglia promotes cholinergic differentiation in the basal forebrain in vitro. Developmental biology vol 177 issue 1 1996 8660879 Conditioned medium from activated microglia promotes cholinergic differentiation in the basal forebrain in vitro. 1996-08-27 2022-01-07 Not clear
G M Jonakait, M B Luskin, R Wei, X F Tian, L N. Conditioned medium from activated microglia promotes cholinergic differentiation in the basal forebrain in vitro. Developmental biology vol 177 issue 1 1996 8660879 Consistent with this hypothesis, conditioned media from cultures of enriched, activated microglia also increased ChAT activity in a dose-dependent fashion. 1996-08-27 2022-01-07 Not clear
G M Jonakait, M B Luskin, R Wei, X F Tian, L N. Conditioned medium from activated microglia promotes cholinergic differentiation in the basal forebrain in vitro. Developmental biology vol 177 issue 1 1996 8660879 In addition, conditioned media from both activated microglia and RAW 264.7 cells increased the proportion of ChAT-positive cells in retrovirally labeled clones to the same extent as IFN itself, suggesting the possibility that they contain the molecule(s) that mediates the action of IFN. 1996-08-27 2022-01-07 Not clear
P E Gottschall, X Yu, B Bin. Increased production of gelatinase B (matrix metalloproteinase-9) and interleukin-6 by activated rat microglia in culture. Journal of neuroscience research vol 42 issue 3 1996 8583501 Conditioned media samples obtained from cultured microglia that were stimulated with various activating agents were subjected to gelatin-substrate zymography. 1996-03-20 2022-01-07 Not clear
S G Wilt, E Milward, J M Zhou, K Nagasato, H Patton, R Rusten, D E Griffin, M O'Connor, M Dubois-Dalc. In vitro evidence for a dual role of tumor necrosis factor-alpha in human immunodeficiency virus type 1 encephalopathy. Annals of neurology vol 37 issue 3 1995 7695238 Addition of live microglia or medium conditioned by these cells also resulted in 30 to 40% oligodendrocyte death, which was largely prevented by TNF-alpha inhibitors. 1995-04-26 2022-01-07 Not clear
J Sievers, R Parwaresch, H U Wottg. Blood monocytes and spleen macrophages differentiate into microglia-like cells on monolayers of astrocytes: morphology. Glia vol 12 issue 4 1995 7890329 When microglia, macrophages, or monocytes are cultured on coverslips on top of astrocytic monolayers, i.e., physically separated from the astroglia, but exposed to the medium conditioned by astrocytes, a significant proportion of them also develop the ramified shape. 1995-04-17 2022-01-07 Not clear
J Schmidtmayer, C Jacobsen, G Miksch, J Siever. Blood monocytes and spleen macrophages differentiate into microglia-like cells on monolayers of astrocytes: membrane currents. Glia vol 12 issue 4 1995 7890330 The expression of the microglia-like membrane currents in the mononuclear phagocytes is induced by a diffusible factor released from the astrocytes into the culture medium, since monocytes and microglia develop the mature microglial current profile, when cultured in astrocyte conditioned medium. 1995-04-17 2022-01-07 Not clear
S P Hamilton, L H Rom. Stimulation of in vitro myelin synthesis by microglia. Glia vol 11 issue 4 1994 7960036 Conditioned medium from cultured microglia provided a similar stimulatory activity, suggesting that the increase in myelin synthesis does not require contact between oligodendrocytes and microglia. 1994-12-27 2022-01-07 Not clear
P J Gebicke-Haerter, K Appel, G D Taylor, A Schobert, I N Rich, H Northoff, M Berge. Rat microglial interleukin-3. Journal of neuroimmunology vol 50 issue 2 1994 8120142 Culture media conditioned by isolated microglia enhanced microglial proliferation above fresh media controls. 1994-04-01 2022-01-07 Not clear
Y Hirose, Y Imai, K Nakajima, N Takemoto, S Toya, S Kohsak. Glial conditioned medium alters the expression of amyloid precursor protein in SH-SY5Y neuroblastoma cells. Biochemical and biophysical research communications vol 198 issue 2 1994 8297361 The effect of conditioned medium from astroglia or microglia cultures on the mRNA expression of amyloid precursor protein (APP) in SH-SY5Y human neuroblastoma cells was examined. 1994-03-01 2022-01-07 Not clear
K Nakajima, N Tsuzaki, K Nagata, N Takemoto, S Kohsak. Production and secretion of plasminogen in cultured rat brain microglia. FEBS letters vol 308 issue 2 1992 1499728 Immunoprecipitation with plasminogen antiserum following [35S]methionine labelling revealed that the plasminogen detected in microglial conditioned medium is synthesized in microglia. 1992-09-16 2022-01-07 Not clear
K Nakajima, N Tsuzaki, M Shimojo, M Hamanoue, S Kohsak. Microglia isolated from rat brain secrete a urokinase-type plasminogen activator. Brain research vol 577 issue 2 1992 1376634 In a previous study, we found particular proteases which degrade myelin basic protein (MBP) in a conditioned medium of cultured rat brain microglia. 1992-07-23 2022-01-07 Not clear
K Nakajima, M Shimojo, M Hamanoue, S Ishiura, H Sugita, S Kohsak. Identification of elastase as a secretory protease from cultured rat microglia. Journal of neurochemistry vol 58 issue 4 1992 1548474 In the course of studying the secretory products of microglia, we detected protease activity in the conditioned medium. 1992-04-17 2022-01-09 Not clear
K Imamura, A Suzumura, M Sawada, T Marunouchi, A Takahash. [Functional and immunohistochemical studies of cultured rat microglia]. Rinsho shinkeigaku = Clinical neurology vol 31 issue 2 1991 2060234 Microglia stimulated with LCM (L929 conditioned medium: colony stimulating factor-1) had proliferative activity and increased acid phosphatase activity. 1991-08-05 2022-01-07 Not clear
C A Colton, J B Yao, D Gilbert, M L Oster-Granit. Enhanced production of superoxide anion by microglia from trisomy 16 mice. Brain research vol 519 issue 1-2 1990 2168783 Superoxide production in the Ts16 media treated rat microglia was significantly higher than in those treated with littermate conditioned media. 1990-10-16 2022-01-07 mouse
M Sawada, A Suzumura, H Yamamoto, T Marunouch. Activation and proliferation of the isolated microglia by colony stimulating factor-1 and possible involvement of protein kinase C. Brain research vol 509 issue 1 1990 2306629 When treated with the conditioned medium of L929 mouse fibroblast cells as a crude CSF-1 (mouse macrophage-colony stimulating factor) or purified CSF-1, microglia showed morphological changes and increased in both cell number and [3H]thymidine uptake. 1990-04-09 2022-01-07 mouse
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