All Relations between conditioned response and microglial cell

Publication Sentence Publish Date Extraction Date Species
Yunn Me Me Paing, Yunkyung Eom, Gyeong Bae Song, Bokyung Kim, Myung Gil Choi, Sungguan Hong, Sung Hoon Le. Neurotoxic effects of polystyrene nanoplastics on memory and microglial activation: Insights from in vivo and in vitro studies. The Science of the total environment. 2024-03-15. PMID:38490422. the application of conditioned media from microglia exposed to psnps suppressed neuronal activity, which was reversed by inhibitors of microglial activation. 2024-03-15 2024-03-18 mouse
Cristiana Alberghina, Filippo Torrisi, Simona D'Aprile, Lucia Longhitano, Sebastiano Giallongo, Grazia Scandura, Giuliana Mannino, Stefania Mele, Maria Gabriella Sabini, Francesco P Cammarata, Giorgio Russo, Ali S Abdelhameed, Agata Zappalà, Debora Lo Furno, Rosario Giuffrida, Giovanni Li Volti, Daniele Tibullo, Nunzio Vicario, Rosalba Parent. Microglia and glioblastoma heterocellular interplay sustains tumour growth and proliferation as an off-target effect of radiotherapy. Cell proliferation. 2024-03-08. PMID:38454614. tumour cells were treated with conditioned media (cm) derived from 0, 2 or 15 gy irradiated gbm cells or 0, 2 or 15 gy irradiated human microglia. 2024-03-08 2024-03-10 human
Azize Yasemin Goksu, Fatma Gonca Kocanci, Ersin Akinci, Devrim Demir-Dora, Fulya Erendor, Salih Sanlioglu, Hilmi Uysa. Microglia cells treated with synthetic vasoactive intestinal peptide or transduced with LentiVIP protect neuronal cells against degeneration. The European journal of neuroscience. 2024-02-21. PMID:38382910. vip secretion in microglial conditioned media (mg cm) for lentivip-infected hmc3 microglia cells was confirmed. 2024-02-21 2024-02-24 human
Kumari Preeti, Anika Sood, Valencia Fernandes, Islauddin Khan, Dharmendra Kumar Khatri, Shashi Bala Sing. Experimental Type 2 diabetes and lipotoxicity-associated neuroinflammation involve mitochondrial DNA-mediated cGAS/STING axis: implication of Type-1 interferon response in cognitive impairment. Molecular neurobiology. 2024-01-29. PMID:38285288. the ifn-β/p-stat1-mediated microglia activation was executed employing a conditioned media approach. 2024-01-29 2024-01-31 mouse
Roberta S Dos Reis, Marc C E Wagner, Savannah McKenna, Velpandi Ayyavo. Neuroinflammation driven by Human Immunodeficiency Virus-1 (HIV-1) directs the expression of long noncoding RNA RP11-677M14.2 resulting in dysregulation of Neurogranin in vivo and in vitro. Research square. 2024-01-23. PMID:38260270. additionally, the nrgn-lncrna axis is dysregulated in neurons exposed to hiv-1 infected microglia conditioned medium enriched with il-1b. 2024-01-23 2024-01-25 human
Irlã Santos Lima, Érica Novaes Soares, Carolina Kymie Vasques Nonaka, Bruno Solano de Freitas Souza, Balbino Lino Dos Santos, Silvia Lima Cost. Flavonoid Rutin Presented Anti-Glioblastoma Activity Related to the Modulation of Onco miRNA-125b Expression and STAT3 Signaling and Impact on Microglia Inflammatory Profile. Brain sciences. vol 14. issue 1. 2024-01-22. PMID:38248305. microglia submitted to the conditioned medium from gbm cells treated with rutin showed reactive morphology associated with reduced expression of il-6, tnf, and stat3. 2024-01-22 2024-01-24 human
Fengchun Wu, Yu Lin, Lili Xiao, Qiyong Chen, Fengfei Lin, Renbin L. Administration with curcumin alleviates spinal cord ischemia-reperfusion injury by regulating anti-oxidative stress and microglia activation-mediated neuroinflammation via Nrf2/NF-κB axis. In vitro cellular & developmental biology. Animal. 2024-01-16. PMID:38228998. importantly, neuronal cells incubated with a conditioned medium from ogd/r-treated microglia exhibited lower cell viability and higher apoptotic ratio, which were overturned when microglia were treated with curcumin. 2024-01-16 2024-01-19 rat
Gabriela Agustina Bulacios, Pablo Gabriel Cataldo, Johana Romina Naja, Elena Posse de Chaves, María Pía Taranto, Carlos Javier Minahk, Elvira María Hebert, María Lucila Saavedr. Improvement of Key Molecular Events Linked to Alzheimer's Disease Pathology Using Postbiotics. ACS omega. vol 8. issue 50. 2023-12-25. PMID:38144080. here, we tested the ability of bacterial conditioned media (bcm) derived from selected lactic acid bacteria (lab) strains to regulate core mechanisms relevant to ad pathophysiology in the microglia cell line bv-2. 2023-12-25 2023-12-27 Not clear
Dan-Jie Wang, Xiao Wang, Shu-le Li, Tong-Tong Zhang, Ya-Chen Yang, Yu-Meng Wang, Xiao-Qiang Zhao, Kun-Yu Li, Yan-Qing Wang, Yan Li, Ke-Ying Zhu, Jun Wan. Sanguinarine modulates microglial function via PPARγ activation and protects against CNS demyelination. International immunopharmacology. vol 127. 2023-12-21. PMID:38128309. this creates a favorable milieu for the differentiation of oligodendrocyte progenitor cells (opcs) when opcs are incubated with conditioned medium from san-treated microglia. 2023-12-21 2023-12-24 mouse
Ingrid Reverte, Claudia Marchetti, Sara Pezza, Soami F Zenoni, Giorgia Scaringi, Laura Ferrucci, Ginevra D'Ottavio, Annabella Pignataro, Diego Andolina, Marcello Raspa, Ferdinando Scavizzi, Marco Venniro, Leslie A Ramsey, Cornelius Gross, Daniele Caprioli, Davide Ragozzin. Microglia-mediated calcium-permeable AMPAR accumulation in the nucleus accumbens drives hyperlocomotion during cocaine withdrawal. Brain, behavior, and immunity. 2023-11-15. PMID:37967660. here, we investigated the role of microglia in nac neuroadaptations after withdrawal from cocaine-induced conditioned place preference (cpp). 2023-11-15 2023-11-20 Not clear
Ingrid Reverte, Claudia Marchetti, Sara Pezza, Soami F Zenoni, Giorgia Scaringi, Laura Ferrucci, Ginevra D'Ottavio, Annabella Pignataro, Diego Andolina, Marcello Raspa, Ferdinando Scavizzi, Marco Venniro, Leslie A Ramsey, Cornelius Gross, Daniele Caprioli, Davide Ragozzin. Microglia-mediated calcium-permeable AMPAR accumulation in the nucleus accumbens drives hyperlocomotion during cocaine withdrawal. Brain, behavior, and immunity. 2023-11-15. PMID:37967660. furthermore, microglia depletion prevented conditioned hyperlocomotion without affecting drug-context associative memory. 2023-11-15 2023-11-20 Not clear
Ning Huang, Jun Tang, Xiaoyao Yi, Maoxin Zhang, Bin Li, Yuan Cheng, Jin Che. Glioma-derived S100A9 polarizes M2 microglia to inhibit CD8+T lymphocytes for immunosuppression via αvβ3 integrin/AKT1/TGFβ1. Biochimica et biophysica acta. Molecular cell research. 2023-10-31. PMID:37907196. then, the medium was collected and considered as conditioned medium (cm), which was incubated with microglia. 2023-10-31 2023-11-08 mouse
Tao Liu, Ziqian Ma, Liang Liu, Yilun Pei, Qichao Wu, Songjie Xu, Yadong Liu, Nan Ding, Yun Guan, Yan Zhang, Xueming Che. Conditioned medium from human dental pulp stem cells treats spinal cord injury by inhibiting microglial pyroptosis. Neural regeneration research. vol 19. issue 5. 2023-10-20. PMID:37862215. in addition, in a lipopolysaccharide-induced bv2 microglia model, conditioned medium from human dental pulp stem cells protected cells from pyroptosis by inhibiting the nlrp3/caspase-1/interleukin-1β pathway. 2023-10-20 2023-11-08 human
Yang-Yang Chen, Wen-Yuan Ju, Guo-Guo Chu, Xiao-Hui Li, Ru-Heng Wei, Qing Wang, Bao-Guo Xiao, Cun-Gen M. [Mechanism of bilobalide promoting neuroprotection of macrophages]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 48. issue 15. 2023-10-06. PMID:37802788. in addition, pc12 cells were incubated with the conditioned medium for eliciting inflammation in bmdms and primary microglia and the count and morphology of cells were observed. 2023-10-06 2023-10-15 mouse
Wei Quan, Cheng-Shi Xu, Xiao-Chong Li, Chao Yang, Tian Lan, Meng-Yue Wang, Dong-Hu Yu, Feng Tang, Ze-Fen Wang, Zhi-Qiang L. Telmisartan inhibits microglia-induced neurotoxic A1 astrocyte conversion via PPARγ-mediated NF-κB/p65 degradation. International immunopharmacology. vol 123. 2023-08-06. PMID:37544025. astrocytes were activated by culturing with the conditioned medium derived from lipopolysaccharide-stimulated microglia. 2023-08-06 2023-08-14 Not clear
Henriette Haukedal, Signe Syshøj Lorenzen, Emil Winther Westi, Giulia I Corsi, Veerendra P Gadekar, Amanda McQuade, Hayk Davtyan, Nadezhda T Doncheva, Benjamin Schmidt, Abinaya Chandrasekaran, Stefan E Seemann, Susanna Cirera, Mathew Blurton-Jones, Morten Meyer, Jan Gorodkin, Blanca I Aldana, Kristine Freud. Alteration of microglial metabolism and inflammatory profile contributes to neurotoxicity in a hiPSC-derived microglia model of frontotemporal dementia 3. Brain, behavior, and immunity. 2023-08-05. PMID:37543250. moreover, hipsc-derived neurons were cultured with conditioned microglia media to investigate disease specific interactions between the two cell populations. 2023-08-05 2023-08-14 human
Henriette Haukedal, Signe Syshøj Lorenzen, Emil Winther Westi, Giulia I Corsi, Veerendra P Gadekar, Amanda McQuade, Hayk Davtyan, Nadezhda T Doncheva, Benjamin Schmidt, Abinaya Chandrasekaran, Stefan E Seemann, Susanna Cirera, Mathew Blurton-Jones, Morten Meyer, Jan Gorodkin, Blanca I Aldana, Kristine Freud. Alteration of microglial metabolism and inflammatory profile contributes to neurotoxicity in a hiPSC-derived microglia model of frontotemporal dementia 3. Brain, behavior, and immunity. 2023-08-05. PMID:37543250. intriguingly, conditioned chmp2b homozygous ftd3 microglia media caused neurotoxic effects, which was not evident for the heterozygous microglia. 2023-08-05 2023-08-14 human
Henriette Haukedal, Signe Syshøj Lorenzen, Emil Winther Westi, Giulia I Corsi, Veerendra P Gadekar, Amanda McQuade, Hayk Davtyan, Nadezhda T Doncheva, Benjamin Schmidt, Abinaya Chandrasekaran, Stefan E Seemann, Susanna Cirera, Mathew Blurton-Jones, Morten Meyer, Jan Gorodkin, Blanca I Aldana, Kristine Freud. Alteration of microglial metabolism and inflammatory profile contributes to neurotoxicity in a hiPSC-derived microglia model of frontotemporal dementia 3. Brain, behavior, and immunity. 2023-08-05. PMID:37543250. strikingly, ifn-γ treatment initiated an immune boost of the chmp2b heterozygous ftd3 microglia, and conditioned microglia media exposure promoted neural outgrowth. 2023-08-05 2023-08-14 human
Huan Yu, Huimin Zhong, Jun Sun, Na Li, Junjue Chen, Bingqiao Shen, Ping Huang, Xi Shen, Shouyue Huang, Yisheng Zhon. Molecular signaling from microglia impacts macroglia autophagy and neurons survival in glaucoma. iScience. vol 26. issue 6. 2023-05-30. PMID:37250793. animals were differently treated with anti-opn, suppressors of opn receptors (itgαvβ3/cd44) or microglia inhibitor minocycline, while isolated retinal müller cells were accordingly treated with conditioned media from microglia culture pretreated with pressuring, overexpression-opn, sir-opn, or minocycline. 2023-05-30 2023-08-14 rat
Zhengjun Zhou, You Zhou, Zhengxuan Huang, Ming Wang, Jie Jiang, Min Yan, Wei Xiang, Shenjie Li, Yang Yu, Ligang Chen, Jie Zhou, Wei Don. Notopterol improves cognitive dysfunction and depression-like behavior via inhibiting STAT3/NF-ĸB pathway mediated inflammation in glioma-bearing mice. International immunopharmacology. vol 118. 2023-04-02. PMID:37004346. notopterol significantly reduced the levels of cytokines (inos, tnf-α, il-6, and il-β) and the activity of stat3/nf-kb signalling pathway in peritumoural brain tissues and gl261 conditioned medium (gcm) treated microglial cell line (bv2 cells). 2023-04-02 2023-08-14 mouse