All Relations between conditioned response and microglial cell

Publication Sentence Publish Date Extraction Date Species
Hyo Won Kim, Jiyoung Kim, Jaekyoon Kim, Siyoung Lee, Bo-Ryoung Choi, Jung-Soo Han, Ki Won Lee, Hyong Joo Le. 3,3'-Diindolylmethane inhibits lipopolysaccharide-induced microglial hyperactivation and attenuates brain inflammation. Toxicological sciences : an official journal of the Society of Toxicology. vol 137. issue 1. 2014-08-28. PMID:24162184. in addition, dim, but not i3c, protected primary cortical neurons from inflammatory toxicity induced by the conditioned media from lps-stimulated bv-2 microglia, indicating that dim might attenuate microglial hyperactivation-mediated neuronal death. 2014-08-28 2023-08-12 mouse
Jaekyoon Kim, Jiyoung Kim, Jaesung Shim, Siyoung Lee, Jisung Kim, Soon Sung Lim, Ki Won Lee, Hyong Joo Le. Licorice-derived dehydroglyasperin C increases MKP-1 expression and suppresses inflammation-mediated neurodegeneration. Neurochemistry international. vol 63. issue 8. 2014-07-22. PMID:24083986. the addition of conditioned media (cm) from dgc- and lps-treated microglia to neurons helped maintain healthy cell body and neurite morphology and increased the number of microtubule-associated protein 2-positive cells and the level of synaptophysin compared to treatment with cm from lps-treated microglia. 2014-07-22 2023-08-12 Not clear
Inelia Morales, José M Jiménez, Marcela Mancilla, Ricardo B Maccion. Tau oligomers and fibrils induce activation of microglial cells. Journal of Alzheimer's disease : JAD. vol 37. issue 4. 2014-07-13. PMID:23948931. furthermore, conditioned media of stimulated microglia cells were exposed to hippocampal neurons generating altered patterns in these cells, including shortening of neuritic processes and cytoskeleton reorganization. 2014-07-13 2023-08-12 Not clear
Hui Sun, Karelle Bénardais, Nancy Stanslowsky, Nadine Thau-Habermann, Niko Hensel, Dongya Huang, Peter Claus, Reinhard Dengler, Martin Stangel, Susanne Petr. Therapeutic potential of mesenchymal stromal cells and MSC conditioned medium in Amyotrophic Lateral Sclerosis (ALS)--in vitro evidence from primary motor neuron cultures, NSC-34 cells, astrocytes and microglia. PloS one. vol 8. issue 9. 2014-04-28. PMID:24069165. therapeutic potential of mesenchymal stromal cells and msc conditioned medium in amyotrophic lateral sclerosis (als)--in vitro evidence from primary motor neuron cultures, nsc-34 cells, astrocytes and microglia. 2014-04-28 2023-08-12 mouse
E P Azevedo, J H Ledo, G Barbosa, M Sobrinho, L Diniz, A C C Fonseca, F Gomes, L Romão, F R S Lima, F L Palhano, S T Ferreira, D Fogue. Activated microglia mediate synapse loss and short-term memory deficits in a mouse model of transthyretin-related oculoleptomeningeal amyloidosis. Cell death & disease. vol 4. 2014-03-12. PMID:24008733. while a25t fibrils were not directly toxic to neurons, the exposure of neuronal cultures to media conditioned by fibril-activated microglia caused synapse loss that culminated in extensive neuronal death via apoptosis. 2014-03-12 2023-08-12 mouse
Rui Ji, Shifu Tian, Helen J Lu, Qingjun Lu, Yan Zheng, Xiaomin Wang, Jixiang Ding, Qiutang Li, Qingxian L. TAM receptors affect adult brain neurogenesis by negative regulation of microglial cell activation. Journal of immunology (Baltimore, Md. : 1950). vol 191. issue 12. 2014-02-18. PMID:24244024. conditioned medium from tko microglia cultures inhibits neuron stem cell proliferation and neuronal differentiation. 2014-02-18 2023-08-12 mouse
Aleksandra Ellert-Miklaszewska, Michal Dabrowski, Maciej Lipko, Marcin Sliwa, Marta Maleszewska, Bozena Kaminsk. Molecular definition of the pro-tumorigenic phenotype of glioma-activated microglia. Glia. vol 61. issue 7. 2014-02-10. PMID:23650109. using primary rat microglial cultures exposed to glioma conditioned medium or lipopolysaccharide (lps), we demonstrate that microglia adapt different fates and polarize into pro-inflammatory or alternatively activated cells. 2014-02-10 2023-08-12 rat
Livio Luongo, Francesca Guida, Serena Boccella, Giulia Bellini, Luisa Gatta, Francesca Rossi, Vito de Novellis, Sabatino Maion. Palmitoylethanolamide reduces formalin-induced neuropathic-like behaviour through spinal glial/microglial phenotypical changes in mice. CNS & neurological disorders drug targets. vol 12. issue 1. 2013-12-23. PMID:23394524. finally, primary microglial cell cultures, conditioned with pea or vehicle, where transplanted in naive and formalin-treated mice, and nociceptive neurons were recorded. 2013-12-23 2023-08-12 mouse
Kakulavarapu V Rama Rao, Monica Brahmbhatt, Michael D Norenber. Microglia contribute to ammonia-induced astrocyte swelling in culture. Metabolic brain disease. vol 28. issue 2. 2013-12-16. PMID:23065046. conditioned media (cm) derived from ammonia-treated cultured microglia when added to cultured astrocytes resulted in significant cell swelling. 2013-12-16 2023-08-12 Not clear
Juan Xiong, Tammy Kielia. Microglia in juvenile neuronal ceroid lipofuscinosis are primed toward a pro-inflammatory phenotype. Journal of neurochemistry. vol 127. issue 2. 2013-12-02. PMID:23919525. conditioned medium from activated cln3(Δex7/8) or wt microglia induced significant cell death in cln3(Δex7/8) but not wt neurons, demonstrating that intrinsically diseased cln3(Δex7/8) neurons are less equipped to withstand cytotoxic insults generated by activated microglia. 2013-12-02 2023-08-12 mouse
Yuanye Li, Gang Chen, Jianya Zhao, Xiaoke Nie, Chunhua Wan, Jiao Liu, Zhiqing Duan, Guangfei X. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) induces microglial nitric oxide production and subsequent rat primary cortical neuron apoptosis through p38/JNK MAPK pathway. Toxicology. vol 312. 2013-11-19. PMID:23969120. in addition, it was demonstrated through treating rat primary cortical neurons with media conditioned with tcdd treated microglia that microglial inos activation mediates neuronal apoptosis. 2013-11-19 2023-08-12 rat
Xia-Yan Zhang, Xiao-Rong Wang, Dong-Min Xu, Shu-Ying Yu, Qiao-Juan Shi, Li-Hui Zhang, Lu Chen, San-Hua Fang, Yun-Bi Lu, Wei-Ping Zhang, Er-Qing We. HAMI 3379, a CysLT2 receptor antagonist, attenuates ischemia-like neuronal injury by inhibiting microglial activation. The Journal of pharmacology and experimental therapeutics. vol 346. issue 2. 2013-09-25. PMID:23750020. moreover, they induced phagocytosis and cytokine release (interleukin-1β and tumor necrosis factor-α) from primary microglia, and conditioned medium from the treated microglia induced neuronal necrosis. 2013-09-25 2023-08-12 Not clear
Yan-Yin Zhao, Jie-Zhong Yu, Qin-Ying Li, Cun-Gen Ma, Chuan-Zhen Lu, Bao-Guo Xia. TSPO-specific ligand vinpocetine exerts a neuroprotective effect by suppressing microglial inflammation. Neuron glia biology. vol 7. issue 2-4. 2013-09-23. PMID:22874716. next, conditioned medium from vinpocetine-treated microglia protected from primary neurons. 2013-09-23 2023-08-12 mouse
N Bali, J M Arimoto, T E Morgan, C E Finc. Progesterone antagonism of neurite outgrowth depends on microglial activation via Pgrmc1/S2R. Endocrinology. vol 154. issue 7. 2013-08-28. PMID:23653459. conditioned media from microglia restored the p4-e2 activity, but only if microglia were activated by lipopolysaccharide or by wounding. 2013-08-28 2023-08-12 rat
J Guadagno, X Xu, M Karajgikar, A Brown, S P Crega. Microglia-derived TNFα induces apoptosis in neural precursor cells via transcriptional activation of the Bcl-2 family member Puma. Cell death & disease. vol 4. 2013-08-23. PMID:23492769. specifically, we show that nf-κb is activated in npcs treated with conditioned media from activated microglia and that puma induction and npc apoptosis is blocked by the nf-κb inhibitor bay-117082. 2013-08-23 2023-08-12 mouse
Xuqing Liu, Huanxing Su, Tak-Ho Chu, Anchen Guo, Wutian W. Minocycline inhibited the pro-apoptotic effect of microglia on neural progenitor cells and protected their neuronal differentiation in vitro. Neuroscience letters. vol 542. 2013-08-15. PMID:23518153. then microglia were activated with lipopolysaccharide (lps) or treated with lps plus minocycline (lpsmc), and the effects of conditioned media on npc apoptosis and differentiation were studied. 2013-08-15 2023-08-12 Not clear
Xuqing Liu, Huanxing Su, Tak-Ho Chu, Anchen Guo, Wutian W. Minocycline inhibited the pro-apoptotic effect of microglia on neural progenitor cells and protected their neuronal differentiation in vitro. Neuroscience letters. vol 542. 2013-08-15. PMID:23518153. the results showed that, compared with lps treatment group, the microglia conditioned media of lpsmc treatment group resulted in a significantly lower apoptotic rate of npcs, and increased the neuronal differentiation of npcs. 2013-08-15 2023-08-12 Not clear
Shankar J Chinta, Abirami Ganesan, Pedro Reis-Rodrigues, Gordon J Lithgow, Julie K Anderse. Anti-inflammatory role of the isoflavone diadzein in lipopolysaccharide-stimulated microglia: implications for Parkinson's disease. Neurotoxicity research. vol 23. issue 2. 2013-06-14. PMID:22573480. furthermore, transfer of conditioned media (cm) from bv-2 cells pretreated with diadzein resulted in a significantly reduction in dopaminergic neurotoxicity compared with cm from microglia stimulated with lps alone. 2013-06-14 2023-08-12 Not clear
Dongmei Zhang, Linlin Sun, Haiyan Zhu, Lan Wang, Weicheng Wu, Jianhui Xie, Jianxin G. Microglial LOX-1 reacts with extracellular HSP60 to bridge neuroinflammation and neurotoxicity. Neurochemistry international. vol 61. issue 7. 2013-06-05. PMID:22847064. in this study, we used medium conditioned by necrotic differentiated-pc12 cells to confirm that damaged neurons can release soluble injury signals, including heat shock protein 60 (hsp60), to efficiently promote the neurotoxic cycle involving microglia. 2013-06-05 2023-08-12 Not clear
Dongmei Zhang, Linlin Sun, Haiyan Zhu, Lan Wang, Weicheng Wu, Jianhui Xie, Jianxin G. Microglial LOX-1 reacts with extracellular HSP60 to bridge neuroinflammation and neurotoxicity. Neurochemistry international. vol 61. issue 7. 2013-06-05. PMID:22847064. in this study, we observed that lox-1 expression is induced upon toxic microglial activation, and discovered that lox-1 is necessary in microglia for sensing soluble neuronal injury signal(s) in the conditioned medium to induce generation of pro-inflammatory mediators (il-1β, tnf-α, no and ros) that promote neurotoxicity. 2013-06-05 2023-08-12 Not clear