All Relations between conditioned response and microglial cell

Publication Sentence Publish Date Extraction Date Species
Weihua Zhao, David R Beers, Bing Liao, Jenny S Henkel, Stanley H Appe. Regulatory T lymphocytes from ALS mice suppress microglia and effector T lymphocytes through different cytokine-mediated mechanisms. Neurobiology of disease. vol 48. issue 3. 2013-04-30. PMID:22820142. when co-cultured with msod1 adult microglia, msod1 tregs suppressed the cytotoxic microglial factors nox2 and inos through an il-4-mediated mechanism, whereas teffs were only minimally effective; il-4 inhibitory antibodies blocked the suppressive function of msod1 tregs, and conditioned media from msod1 tregs or the addition of il-4 reduced microglial nox2 expression. 2013-04-30 2023-08-12 mouse
Bart R Tambuyzer, Christophe Casteleyn, Hans Vergauwen, Steven Van Cruchten, Chris Van Ginneke. Osteopontin alters the functional profile of porcine microglia in vitro. Cell biology international. vol 36. issue 12. 2013-04-23. PMID:22974008. moreover, conditioned medium of llc-pk1 cells, a pig renal epithelial cell line and a known source of secreted opn, more than doubled the rate of proliferation of microglia. 2013-04-23 2023-08-12 Not clear
Hyemin Kim, June-Hee Park, Kyungjin Ki. Lipid-like components released from degenerating dopaminergic neurons trigger the dynamic migration of microglia. Biochemical and biophysical research communications. vol 426. issue 1. 2013-01-31. PMID:22898047. transmigration assay showed that the conditioned medium (cm) from mesencephalic cultures treated with mpp(+) was enough to trigger the attraction of microglia at an early as well as a late phase of neuronal damage. 2013-01-31 2023-08-12 Not clear
Lauren Herl Martens, Jiasheng Zhang, Sami J Barmada, Ping Zhou, Sherry Kamiya, Binggui Sun, Sang-Won Min, Li Gan, Steven Finkbeiner, Eric J Huang, Robert V Fares. Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury. The Journal of clinical investigation. vol 122. issue 11. 2013-01-15. PMID:23041626. furthermore, grn⁻/⁻ microglia treated with lps/ifn-γ exhibited an amplified inflammatory response, and conditioned media from these microglia promoted death of cultured neurons. 2013-01-15 2023-08-12 mouse
Sandra L Silva, Ana R Vaz, Maria J Diógenes, Nico van Rooijen, Ana M Sebastião, Adelaide Fernandes, Rui F M Silva, Dora Brite. Neuritic growth impairment and cell death by unconjugated bilirubin is mediated by NO and glutamate, modulated by microglia, and prevented by glycoursodeoxycholic acid and interleukin-10. Neuropharmacology. vol 62. issue 7. 2012-12-20. PMID:22361233. our studies demonstrated that neurite outgrowth deficits are produced in neurons exposed to ucb and that conditioned media from these ucb-treated neurons further stimulate no production by microglia. 2012-12-20 2023-08-12 Not clear
Yanji Cui, Jinji Wu, Sung-Cherl Jung, Gi-Ok Kim, Ryeo Kyeong Ko, Hye-Ja Lee, Eun-Sook Yoo, Hee-Kyoung Kang, Kyoungho Suk, Su-Yong Eu. Neuroprotective effect of methyl lucidone against microglia-mediated neurotoxicity. European journal of pharmacology. vol 690. issue 1-3. 2012-12-17. PMID:22683871. the cell viabilities of ht-22 neurons were significantly attenuated by treatment of the conditioned media containing neurotoxic secretary molecules from lps-stimulated microglia. 2012-12-17 2023-08-12 Not clear
Sandra Moreira Rocha, Ana Clara Cristovão, Filipa Lopes Campos, Carla Pais Fonseca, Graça Baltaza. Astrocyte-derived GDNF is a potent inhibitor of microglial activation. Neurobiology of disease. vol 47. issue 3. 2012-11-29. PMID:22579772. in the present study, using zymosan a-stimulated midbrain microglia cultures, we showed that astrocytes secrete factors capable of modulating microglial activation, namely its phagocytic activity and the production of reactive oxygen species since both parameters were highly diminished in cells incubated with astrocytes conditioned media (acm). 2012-11-29 2023-08-12 Not clear
Sandra Moreira Rocha, Ana Clara Cristovão, Filipa Lopes Campos, Carla Pais Fonseca, Graça Baltaza. Astrocyte-derived GDNF is a potent inhibitor of microglial activation. Neurobiology of disease. vol 47. issue 3. 2012-11-29. PMID:22579772. in addition, media conditioned by astrocytes silenced for gdnf were not able to prevent microglial activation, whereas supplementation of non-conditioned media with gdnf prevented the activation of microglia evoked by zymosan a. 2012-11-29 2023-08-12 Not clear
Samar Etemad, Rasheeda Mohd Zamin, Marc J Ruitenberg, Luis Filgueir. A novel in vitro human microglia model: characterization of human monocyte-derived microglia. Journal of neuroscience methods. vol 209. issue 1. 2012-11-23. PMID:22659341. the described protocol for the generation of human monocyte-derived microglia is feasible, well standardized and reliable, as it uses well defined culture medium and recombinant cytokines, but no serum or conditioned medium. 2012-11-23 2023-08-12 human
Bart R Tambuyzer, Christophe Casteleyn, Steven Van Cruchten, Peter Ponsaerts, Chris Van Ginneke. Interferon-γ modulates the functional profile of in-vitro-cultured porcine microglia. Neuroreport. vol 23. issue 9. 2012-10-17. PMID:22581042. the effect of several exogenous stimuli [phorbol myristate acetate, conditioned medium, interferon γ (ifn-γ)] on the in-vitro functional properties of porcine microglia is investigated using this test. 2012-10-17 2023-08-12 Not clear
G Miller Jonakait, Lorelei Pratt, Giselles Acevedo, Li N. Microglial regulation of cholinergic differentiation in the basal forebrain. Developmental neurobiology. vol 72. issue 6. 2012-09-28. PMID:21898853. conditioned medium (cm) taken from microglia stimulated variously (microglial cm; mcm) increased activity of choline acetyltransferase (chat), the enzyme responsible for acetylcholine biosynthesis and a phenotypic hallmark of the cholinergic neuron. 2012-09-28 2023-08-12 rat
Ashley S Harms, Jae-Kyung Lee, Thi A Nguyen, Jianjun Chang, Kelly M Ruhn, Isaac Treviño, Malú G Tanse. Regulation of microglia effector functions by tumor necrosis factor signaling. Glia. vol 60. issue 2. 2012-08-24. PMID:21989628. functionally, conditioned media from lps-stimulated tnf-null microglia was found to have significantly reduced levels of il-10, il-6, il-1β, il-12, and cxcl1 relative to wild-type microglia and exerted no cytotoxic effects on neurally differentiated dopaminergic (da) mn9d cells. 2012-08-24 2023-08-12 mouse
Sadayuki Hashioka, James G McLarnon, Jae K Ryu, Amal M Youssef, Alaa S Abd-El-Aziz, Edward G Neeland, Andis Klegeri. Pyrazole compound 2-MBAPA as a novel inhibitor of microglial activation and neurotoxicity in vitro and in vivo. Journal of Alzheimer's disease : JAD. vol 27. issue 3. 2012-08-20. PMID:21841251. the compound at a non-toxic concentration inhibited secretion of tumor necrosis factor (tnf)-α by activated human microglia and attenuated toxicity of conditioned medium from activated human microglia towards human sh-sy5y neuroblastoma cells in vitro. 2012-08-20 2023-08-12 human
F Gillardon, R Schmid, H Drahei. Parkinson's disease-linked leucine-rich repeat kinase 2(R1441G) mutation increases proinflammatory cytokine release from activated primary microglial cells and resultant neurotoxicity. Neuroscience. vol 208. 2012-07-20. PMID:22342962. consistently, conditioned medium from lps-stimulated lrrk2(r1441g) transgenic microglia induced significant cell death when added to neuronal cultures. 2012-07-20 2023-08-12 mouse
Maria Antonietta Ajmone-Cat, Maria Lavinia Salvatori, Roberta De Simone, Melissa Mancini, Stefano Biagioni, Antonietta Bernardo, Emanuele Cacci, Luisa Minghett. Docosahexaenoic acid modulates inflammatory and antineurogenic functions of activated microglial cells. Journal of neuroscience research. vol 90. issue 3. 2012-07-19. PMID:22057807. acutely activated microglia ortheir conditioned media (cm) reduce neural stem progenitor cell (npc) survival and prevent npc differentiation into neurons. 2012-07-19 2023-08-12 Not clear
Maria Antonietta Ajmone-Cat, Maria Lavinia Salvatori, Roberta De Simone, Melissa Mancini, Stefano Biagioni, Antonietta Bernardo, Emanuele Cacci, Luisa Minghett. Docosahexaenoic acid modulates inflammatory and antineurogenic functions of activated microglial cells. Journal of neuroscience research. vol 90. issue 3. 2012-07-19. PMID:22057807. the attenuation of m1 proinflammatory phenotype has relevant consequences for the survival and differentiation of npc, because dha reverses the antineurogenic activities of conditioned media from lps-activated microglia. 2012-07-19 2023-08-12 Not clear
Moonhee Lee, Byoung-Mog Kwon, Byoung-Mok Kwon, Kyoungho Suk, Edith McGeer, Patrick L McGee. Effects of obovatol on GSH depleted glia-mediated neurotoxicity and oxidative damage. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. vol 7. issue 1. 2012-06-12. PMID:21796424. prior treatment with obo potentiated survival of sh-sy5y cells exposed to conditioned medium from bso-treated thp-1, u373 cells, microglia and astrocytes. 2012-06-12 2023-08-12 human
Xue-Qin Zhang, Yu Cui, Yue Cui, Yu Chen, Xiao-Dong Na, Feng-Ying Chen, Xu-Hong Wei, Yong-Yong Li, Xian-Guo Liu, Wen-Jun Xi. Activation of p38 signaling in the microglia in the nucleus accumbens contributes to the acquisition and maintenance of morphine-induced conditioned place preference. Brain, behavior, and immunity. vol 26. issue 2. 2012-05-17. PMID:22004988. activation of p38 signaling in the microglia in the nucleus accumbens contributes to the acquisition and maintenance of morphine-induced conditioned place preference. 2012-05-17 2023-08-12 rat
A C C da Fonseca, L Romão, R F Amaral, S Assad Kahn, D Lobo, S Martins, J Marcondes de Souza, V Moura-Neto, F R S Lim. Microglial stress inducible protein 1 promotes proliferation and migration in human glioblastoma cells. Neuroscience. vol 200. 2012-05-07. PMID:22062133. we demonstrated that soluble factors secreted by microglia into the culture medium (microglia conditioned medium; mg cm) caused a two-fold increase in the proliferation of gbm95 cells. 2012-05-07 2023-08-12 human
Jun Wang, Peng-Tao Li, Huan Du, Jin-Cai Hou, Wei-Hong Li, Yan-Shu Pan, Qian Hua, Hui-Cong Che. Impact of paracrine signals from brain microvascular endothelial cells on microglial proliferation and migration. Brain research bulletin. vol 86. issue 1-2. 2012-04-04. PMID:21756984. therefore, we examined the effects of normal bmecs conditioned medium (bmecs-cm) on activated microglia induced by pro-inflammatory cytokine macrophage inflammatory protein-1beta (mip-1β), a chemokine that released from ischemic bmecs and has been proved to stimulate microglial proliferation. 2012-04-04 2023-08-12 Not clear