| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sébastien Tilleux, Emmanuel Herman. Down-regulation of astrocytic GLAST by microglia-related inflammation is abrogated in dibutyryl cAMP-differentiated cultures. Journal of neurochemistry. vol 105. issue 6. 2010-08-13. PMID:18298666. |
the influence of neuroinflammation on glutamate uptake by glial cells was examined after exposing primary cultures of rat astrocytes to conditioned culture medium from lipopolysaccharide-activated microglia. |
2010-08-13 |
2023-08-12 |
rat |
| Sébastien Tilleux, Emmanuel Herman. Down-regulation of astrocytic GLAST by microglia-related inflammation is abrogated in dibutyryl cAMP-differentiated cultures. Journal of neurochemistry. vol 105. issue 6. 2010-08-13. PMID:18298666. |
in this model, the conditioned culture medium from activated microglia, as well as tnf-alpha, were found to increase glutamate uptake capacity. |
2010-08-13 |
2023-08-12 |
rat |
| May-Jywan Tsai, Yi-Ming Arthur Chen, Ching-Feng Weng, Dann-Ying Liou, Hsin-Chun Yang, Chien-Hung Chen, Roanna I-Hsin Liao, Fu-Shan Kuo, Chiuan-Wen Chiu, Huai-Sheng Kuo, Ming-Chao Huang, Yi-Lo Lin, Meng-Jen Lee, Wen-Chun Kuo, Wen-Cheng Huang, Henrich Chen. Enhanced expression of glycine N-methyltransferase by adenovirus-mediated gene transfer in CNS culture is neuroprotective. Annals of the New York Academy of Sciences. vol 1199. 2010-07-29. PMID:20633125. |
conditioned media from ad-gnmt-infected microglia also significantly enhance neuronal survival. |
2010-07-29 |
2023-08-12 |
Not clear |
| Honghong Yao, Yanjing Yang, Kee Jun Kim, Crystal Bethel-Brown, Nan Gong, Keiko Funa, Howard E Gendelman, Tsung-Ping Su, John Q Wang, Shilpa Buc. Molecular mechanisms involving sigma receptor-mediated induction of MCP-1: implication for increased monocyte transmigration. Blood. vol 115. issue 23. 2010-07-19. PMID:20354174. |
furthermore, conditioned media from cocaine-exposed microglia increased monocyte transmigration, and thus was blocked by antagonists for ccr2 or sigma receptor. |
2010-07-19 |
2023-08-12 |
mouse |
| Deanna L Taylor, Grisha Pirianov, Samantha Holland, Colm J McGinnity, Adele L Norman, Camilla Reali, Lara T Diemel, Djordje Gveric, Davy Yeung, Huseyin Mehme. Attenuation of proliferation in oligodendrocyte precursor cells by activated microglia. Journal of neuroscience research. vol 88. issue 8. 2010-07-12. PMID:20091773. |
microglial conditioned medium (mgcm) from lps-activated microglia attenuated primary opc proliferation without inducing cell death. |
2010-07-12 |
2023-08-12 |
rat |
| Claudia Röhl, Elisabeth Armbrust, Eva Herbst, Anne Jess, Michael Gülden, Edmund Maser, Gerald Rimbach, Christine Bösch-Saadatmand. Mechanisms involved in the modulation of astroglial resistance to oxidative stress induced by activated microglia: antioxidative systems, peroxide elimination, radical generation, lipid peroxidation. Neurotoxicity research. vol 17. issue 4. 2010-06-23. PMID:19763738. |
astrocytes were treated for 3 days with medium conditioned by purified quiescent (microglia-conditioned medium, mcm[-]) or lps-activated (mcm[+]) microglia. |
2010-06-23 |
2023-08-12 |
Not clear |
| Li-Fang Hu, Ming Lu, Chi Xin Tiong, Gavin S Dawe, Gang Hu, Jin-Song Bia. Neuroprotective effects of hydrogen sulfide on Parkinson's disease rat models. Aging cell. vol 9. issue 2. 2010-06-10. PMID:20041858. |
moreover, significantly less neurotoxicity was found in neurons treated with the conditioned medium from microglia incubated with both nahs and rotenone compared to that with rotenone only, suggesting that the therapeutic effect of nahs was, at least partially, secondary to its suppression of microglial activation. |
2010-06-10 |
2023-08-12 |
rat |
| Izumi Maezawa, Lee-Way Ji. Rett syndrome microglia damage dendrites and synapses by the elevated release of glutamate. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 15. 2010-05-14. PMID:20392956. |
here we report a potent neurotoxic activity in the conditioned medium (cm) obtained from mecp2-null microglia. |
2010-05-14 |
2023-08-12 |
Not clear |
| Jun-Li Liu, Dai-Shi Tian, Zai-Wang Li, Wen-Sheng Qu, Yan Zhan, Min-Jie Xie, Zhi-Yuan Yu, Wei Wang, Gang W. Tamoxifen alleviates irradiation-induced brain injury by attenuating microglial inflammatory response in vitro and in vivo. Brain research. vol 1316. 2010-05-06. PMID:20044983. |
irradiating bv-2 cells (a murine microglial cell line) with various radiation doses (2-10 gy) led to the increase in il-1 beta and tnf-alpha expression determined by elisa, and the conditioned culture medium of irradiated microglia with 10 gy radiation dose initiated astroglial activation and decreased the number of neuronal cells in vitro. |
2010-05-06 |
2023-08-12 |
Not clear |
| Y Pang, L Campbell, B Zheng, L Fan, Z Cai, P Rhode. Lipopolysaccharide-activated microglia induce death of oligodendrocyte progenitor cells and impede their development. Neuroscience. vol 166. issue 2. 2010-05-03. PMID:20035837. |
furthermore, microglia-derived insulin-like growth factor-1 (igf-1) and ciliary neurotrophic factor (cntf) were significantly suppressed by lps, and exogenous igf-1 and cntf synergistically protected ols from death induced by lps-treated microglia conditioned medium, indicating that a deficiency in trophic support may also be involved in ol death. |
2010-05-03 |
2023-08-12 |
Not clear |
| M Noda, T Seike, K Fujita, Y Yamakawa, M Kido, H Iguch. The role of immune cells in brain metastasis of lung cancer cells and neuron-tumor cell interaction. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. vol 95. issue 12. 2010-03-09. PMID:20141048. |
in vitro study, conditioned medium from primary cultured mouse microglia inhibited the proliferation of tumor cells, while tumor cell-conditioned medium inhibited the proliferation of primary cultured neurons from mouse cortex. |
2010-03-09 |
2023-08-12 |
mouse |
| Balini Balasubramaniam, Debra A Carter, Eric J Mayer, Andrew D Dic. Microglia derived IL-6 suppresses neurosphere generation from adult human retinal cell suspensions. Experimental eye research. vol 89. issue 5. 2010-02-04. PMID:19596318. |
following culture of retinal explants for 4 days, supernatant conditioned by resulting migrated microglia was collected after a further 3 days and fed to retinal cell suspensions (rcs). |
2010-02-04 |
2023-08-12 |
human |
| Lan-Feng Chu, Wei-Ti Wang, Vithal K Ghanta, Chi-Hsin Lin, Yung-Yen Chiang, Chi-Mei Hsue. Ischemic brain cell-derived conditioned medium protects astrocytes against ischemia through GDNF/ERK/NF-kB signaling pathway. Brain research. vol 1239. 2010-01-12. PMID:18804095. |
conditioned medium (cm) collected from cultures of ischemic microglia, astrocytes, and neurons were protective to astrocytes under the in vitro ischemic condition (deprivation of oxygen, glucose and serum). |
2010-01-12 |
2023-08-12 |
Not clear |
| So-Young Hwang, Byong-Chul Yoo, Jae-won Jung, Eok-Soo Oh, Ji-Sun Hwang, Jin-A Shin, Song-Yi Kim, Seok-Ho Cha, Inn-Oc Ha. Induction of glioma apoptosis by microglia-secreted molecules: The role of nitric oxide and cathepsin B. Biochimica et biophysica acta. vol 1793. issue 11. 2009-12-23. PMID:19748528. |
microglia conditioned culture medium (mcm) actively stimulated apoptotic death of glioma cells, and the effects of mcm prepared from lps- or ifn-gamma-activated microglia were more pronounced. |
2009-12-23 |
2023-08-12 |
rat |
| G Miller Jonakait, Li N. Prostaglandins compromise basal forebrain cholinergic neuron differentiation and survival: action at EP1/3 receptors results in AIF-induced death. Brain research. vol 1285. 2009-12-15. PMID:19555672. |
to determine whether microglial prostaglandins mediate this action, microglia were stimulated in the presence of the cyclooxygenase inhibitor ibuprofen, and microglial conditioned medium (cm) was used to culture rat bf precursors at embryonic day 15. |
2009-12-15 |
2023-08-12 |
rat |
| Van B Lu, James E Biggs, Martin J Stebbing, Sridhar Balasubramanyan, Kathryn G Todd, Aaron Y Lai, William F Colmers, David Dawbarn, Klaus Ballanyi, Peter A Smit. Brain-derived neurotrophic factor drives the changes in excitatory synaptic transmission in the rat superficial dorsal horn that follow sciatic nerve injury. The Journal of physiology. vol 587. issue Pt 5. 2009-12-07. PMID:19124536. |
in addition, defined-medium organotypic spinal cord slice cultures were exposed for 5-6 days to brain-derived neurotrophic factor (bdnf, 200 ng ml(-1)) or to medium conditioned with activated microglia (amcm). |
2009-12-07 |
2023-08-12 |
rat |
| Marcia Toguchi, Daniel Gonzalez, Sohei Furukawa, Shinobu Inagak. Involvement of Sema4D in the control of microglia activation. Neurochemistry international. vol 55. issue 7. 2009-11-17. PMID:19467284. |
microglia were cultured, activated by bacterial endotoxin lipopolysaccharide (lps) and then, exposed to sema4d/cd100 or conditioned medium. |
2009-11-17 |
2023-08-12 |
mouse |
| Chang Zhou, Chen Zhang, Song Chi, Yiongfeng Xu, Jijun Teng, Haiping Wang, Yuqiang Song, Renliang Zha. Effects of human marrow stromal cells on activation of microglial cells and production of inflammatory factors induced by lipopolysaccharide. Brain research. vol 1269. 2009-07-29. PMID:19269277. |
our results showed that the production of insulin-like growth factor-1 (igf-1), vascular endothelial growth factor (vegf), brain-derived neurotrophic factor (bdnf), and hepatocyte growth factor (hgf) was significantly increased by hmscs when cultured in the conditioned medium from activated microglia. |
2009-07-29 |
2023-08-12 |
human |
| Sébastien Tilleux, Stéphanie Goursaud, Emmanuel Herman. Selective up-regulation of GLT-1 in cultured astrocytes exposed to soluble mediators released by activated microglia. Neurochemistry international. vol 55. issue 1-3. 2009-07-15. PMID:19428805. |
the regulation of the expression and activity of type 1 glutamate transporter (glt-1) was examined after exposing cultures of rat astrocytes to conditioned medium from lipopolysaccharide-activated microglia cultures. |
2009-07-15 |
2023-08-12 |
rat |
| Koji Fukui, Shiro Urano, Tatsuro Koik. Releasing factors from mature neurons modulate microglial survival via purinergic receptor activation. Neuroscience letters. vol 456. issue 2. 2009-07-15. PMID:19429135. |
treatment with conditioned medium of mature cerebellar granule neurons (cgcs) and cortical neurons significantly induced the death of lipopolysaccharide (lps)-stimulated microglia. |
2009-07-15 |
2023-08-12 |
Not clear |