Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Koji Fukui, Shiro Urano, Tatsuro Koik. Releasing factors from mature neurons modulate microglial survival via purinergic receptor activation. Neuroscience letters. vol 456. issue 2. 2009-07-15. PMID:19429135. |
on the other hand, treatment with conditioned medium of mature superior ganglion neurons induced microglial cell death in neither the presence nor absence of lps. |
2009-07-15 |
2023-08-12 |
Not clear |
Koji Fukui, Shiro Urano, Tatsuro Koik. Releasing factors from mature neurons modulate microglial survival via purinergic receptor activation. Neuroscience letters. vol 456. issue 2. 2009-07-15. PMID:19429135. |
in contrast, treatment with heat-treated conditioned medium or low-calcium ion medium prevented the death of lps-stimulated microglia. |
2009-07-15 |
2023-08-12 |
Not clear |
Dan Zhang, Xiaoming Hu, Li Qian, Belinda Wilson, Christopher Lee, Patrick Flood, Robert Langenbach, Jau-Shyong Hon. Prostaglandin E2 released from activated microglia enhances astrocyte proliferation in vitro. Toxicology and applied pharmacology. vol 238. issue 1. 2009-06-22. PMID:19397918. |
furthermore, increased proliferation of astrocytes was observed in the presence of conditioned media from lps-treated microglia. |
2009-06-22 |
2023-08-12 |
Not clear |
Claudie Hooper, Fleur Pinteaux-Jones, Victoria A H Fry, Ioanna G Sevastou, David Baker, Simon J Heales, Jennifer M Pococ. Differential effects of albumin on microglia and macrophages; implications for neurodegeneration following blood-brain barrier damage. Journal of neurochemistry. vol 109. issue 3. 2009-06-09. PMID:19187440. |
conditioned medium from microglia exposed to albumin or fraction v was neurotoxic. |
2009-06-09 |
2023-08-12 |
rat |
Huaqi Xiong, Debbie Callaghan, Aimee Jones, Jianying Bai, Ingrid Rasquinha, Catherine Smith, Ke Pei, Douglas Walker, Lih-Fen Lue, Danica Stanimirovic, Wandong Zhan. ABCG2 is upregulated in Alzheimer's brain with cerebral amyloid angiopathy and may act as a gatekeeper at the blood-brain barrier for Abeta(1-40) peptides. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 17. 2009-06-03. PMID:19403814. |
abeta alone or in combination with hypoxia/ischemia failed to stimulate abcg2 expression in bbb endothelial cells; however, conditioned media from abeta-activated microglia strongly induced abcg2 expression. |
2009-06-03 |
2023-08-12 |
mouse |
Kyungmi Koh, Youngnam Cha, Sunyoung Kim, Jiyoung Ki. tBHQ inhibits LPS-induced microglial activation via Nrf2-mediated suppression of p38 phosphorylation. Biochemical and biophysical research communications. vol 380. issue 3. 2009-04-20. PMID:19174151. |
conditioned culture media taken from lps-stimulated microglia cause neuronal death. |
2009-04-20 |
2023-08-12 |
Not clear |
Kyungmi Koh, Youngnam Cha, Sunyoung Kim, Jiyoung Ki. tBHQ inhibits LPS-induced microglial activation via Nrf2-mediated suppression of p38 phosphorylation. Biochemical and biophysical research communications. vol 380. issue 3. 2009-04-20. PMID:19174151. |
however, the conditioned media taken from tbhq-pretreated and lps-stimulated microglia did not cause death of primary neurons. |
2009-04-20 |
2023-08-12 |
Not clear |
Penglian Wang, Nancy J Rothwell, Emmanuel Pinteaux, David Broug. Neuronal injury induces the release of pro-interleukin-1beta from activated microglia in vitro. Brain research. vol 1236. 2009-04-16. PMID:18722361. |
in addition, we show that pro-il-1beta release from lps-treated mixed glia or lps-treated microglia is significantly reduced in the presence of conditioned medium from healthy co-cultures or neuronal cultures respectively. |
2009-04-16 |
2023-08-12 |
rat |
Simona Eleuteri, Elisabetta Polazzi, Antonio Contestabil. Neuroprotection of microglia conditioned media from apoptotic death induced by staurosporine and glutamate in cultures of rat cerebellar granule cells. Neuroscience letters. vol 448. issue 1. 2009-04-16. PMID:18950681. |
neuroprotection of microglia conditioned media from apoptotic death induced by staurosporine and glutamate in cultures of rat cerebellar granule cells. |
2009-04-16 |
2023-08-12 |
rat |
Simona Eleuteri, Elisabetta Polazzi, Antonio Contestabil. Neuroprotection of microglia conditioned media from apoptotic death induced by staurosporine and glutamate in cultures of rat cerebellar granule cells. Neuroscience letters. vol 448. issue 1. 2009-04-16. PMID:18950681. |
we have tested the efficacy of media directly conditioned by microglia or conditioned by microglia after having been exposed to apoptotic neurons, towards neuroprotection of rat cerebellar granule cells (cgcs) challenged with staurosporine or glutamate. |
2009-04-16 |
2023-08-12 |
rat |
Simona Eleuteri, Elisabetta Polazzi, Antonio Contestabil. Neuroprotection of microglia conditioned media from apoptotic death induced by staurosporine and glutamate in cultures of rat cerebellar granule cells. Neuroscience letters. vol 448. issue 1. 2009-04-16. PMID:18950681. |
apoptotic death of cgc caused by staurosporine, as well as by a mild excitotoxic stimulus delivered through sub-chronic glutamate treatment, was significantly counteracted by microglia conditioned media. |
2009-04-16 |
2023-08-12 |
rat |
Simona Eleuteri, Elisabetta Polazzi, Antonio Contestabil. Neuroprotection of microglia conditioned media from apoptotic death induced by staurosporine and glutamate in cultures of rat cerebellar granule cells. Neuroscience letters. vol 448. issue 1. 2009-04-16. PMID:18950681. |
on the other hand, an acute excitotoxic insult delivered through a short pulse of glutamate exposure in the absence of magnesium and resulting in a mix of apoptotic and necrotic death was only marginally counteracted by microglia conditioned media. |
2009-04-16 |
2023-08-12 |
rat |
Claudia Röhl, Elisabeth Armbrust, Karola Kolbe, Ralph Lucius, Edmund Maser, Simone Venz, Michael Gülde. Activated microglia modulate astroglial enzymes involved in oxidative and inflammatory stress and increase the resistance of astrocytes to oxidative stress in vitro. Glia. vol 56. issue 10. 2008-11-10. PMID:18442093. |
to examine the effects of activated microglia on astrocytes purified rat astroglial cell cultures were treated with medium conditioned by purified quiescent (mcm[-]) or lipopolysaccharide (lps)-activated rat microglia (mcm[+]) and subjected to a comparative proteome analysis based on two-dimensional gel electrophoresis. |
2008-11-10 |
2023-08-12 |
rat |
Stefanie Ebert, Tobias Schoeberl, Yana Walczak, Katharina Stoecker, Thomas Stempfl, Christoph Moehle, Bernhard H F Weber, Thomas Langman. Chondroitin sulfate disaccharide stimulates microglia to adopt a novel regulatory phenotype. Journal of leukocyte biology. vol 84. issue 3. 2008-10-28. PMID:18550791. |
furthermore, conditioned media from cspg-ds-treated microglia did not diminish the viability or cause apoptosis of cultured photoreceptor cells and partially rescued these cells from ifn-gamma-induced apoptosis. |
2008-10-28 |
2023-08-12 |
Not clear |
Se Hoon Choi, Karthikeyan Veeraraghavalu, Orly Lazarov, Seoan Marler, Richard M Ransohoff, Jan Marino Ramirez, Sangram S Sisodi. Non-cell-autonomous effects of presenilin 1 variants on enrichment-mediated hippocampal progenitor cell proliferation and differentiation. Neuron. vol 59. issue 4. 2008-09-29. PMID:18760694. |
on the other hand, wild-type npcs cocultured with primary microglia from mice expressing ps1 variants exhibit impaired proliferation and neuronal lineage commitment, phenotypes that are recapitulated with mutant microglia conditioned media in which we detect altered levels of selected soluble signaling factors. |
2008-09-29 |
2023-08-12 |
mouse |
Katharine Striedinger, Eliana Sceme. Interleukin-1beta affects calcium signaling and in vitro cell migration of astrocyte progenitors. Journal of neuroimmunology. vol 196. issue 1-2. 2008-09-24. PMID:18462808. |
here we provide evidence that conditioned medium from activated microglia and interleukin-1beta, but not tumor necrosis factor-alpha, decrease the frequency of calcium oscillations and reduce the rate of in vitro migration of astrocyte progenitors. |
2008-09-24 |
2023-08-12 |
Not clear |
E Armbrust, C Röh. Time- and activation-dependency of the protective effect of microglia on astrocytes exposed to peroxide-induced oxidative stress. Toxicology in vitro : an international journal published in association with BIBRA. vol 22. issue 5. 2008-08-29. PMID:18367369. |
astrocytes were pre-treated with conditioned medium from lipopolysaccharides (lps)-activated microglia and then exposed to oxidative stress induced by h2o2 under varying conditions. |
2008-08-29 |
2023-08-12 |
rat |
E Armbrust, C Röh. Time- and activation-dependency of the protective effect of microglia on astrocytes exposed to peroxide-induced oxidative stress. Toxicology in vitro : an international journal published in association with BIBRA. vol 22. issue 5. 2008-08-29. PMID:18367369. |
as well in the indirect co-culture model using conditioned medium of microglia as in a direct co-culture model with different portions of microglial cells on the astroglial monolayer the astroprotective effect clearly correlated with the degree of microglial activation. |
2008-08-29 |
2023-08-12 |
rat |
Kazuyuki Nakajima, Shinichi Yamamoto, Shinichi Kohsaka, Tadashi Kurihar. Neuronal stimulation leading to upregulation of glutamate transporter-1 (GLT-1) in rat microglia in vitro. Neuroscience letters. vol 436. issue 3. 2008-08-25. PMID:18406522. |
a 14c-glu uptake experiment revealed that microglia enhance uptake of glu by stimulation with neuronal conditioned medium (ncm). |
2008-08-25 |
2023-08-12 |
rat |
Yuichi Matsushita, Kazuyuki Nakajima, Yoko Tohyama, Tadashi Kurihara, Shinichi Kohsak. Activation of microglia by endotoxin suppresses the secretion of glial cell line-derived neurotrophic factor (GDNF) through the action of protein kinase C alpha (PKCalpha) and mitogen-activated protein kinases (MAPKS). Journal of neuroscience research. vol 86. issue 9. 2008-08-20. PMID:18438912. |
comparison of the amounts of gdnf in the cells and the conditioned medium between the nonstimulated microglia and lps-stimulated microglia clarified that the secretion of gdnf, but not its production, is strongly suppressed when the microglia are activated with lps. |
2008-08-20 |
2023-08-12 |
Not clear |