| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiao-dong Pan, Xiao-chun Chen, Yuan-gui Zhu, Jing Zhang, Tian-wen Huang, Li-min Chen, Qin-yong Ye, Hua-pin Huan. Neuroprotective role of tripchlorolide on inflammatory neurotoxicity induced by lipopolysaccharide-activated microglia. Biochemical pharmacology. vol 76. issue 3. 2008-08-04. PMID:18602088. |
moreover, tripchlorolide protected primary cortical neurons and neuro-2a cells from neuroinflammatory toxicity induced by the conditioned media from lipopolysaccharide (lps)-stimulated microglia, which resulted in a significant decrease in their cell survival. |
2008-08-04 |
2023-08-12 |
Not clear |
| Clotilde Lauro, Silvia Di Angelantonio, Raffaela Cipriani, Fabrizia Sobrero, Letizia Antonilli, Valentina Brusadin, Davide Ragozzino, Cristina Limatol. Activity of adenosine receptors type 1 Is required for CX3CL1-mediated neuroprotection and neuromodulation in hippocampal neurons. Journal of immunology (Baltimore, Md. : 1950). vol 180. issue 11. 2008-07-18. PMID:18490761. |
using cultured hippocampal neuronal cell preparations, obtained from cx(3)cr1(-/-) (cx(3)cr1(gfp/gfp)) mice, we report that these same effects are mimicked by exposing neurons to a medium conditioned with cx(3)cl1-treated mouse microglial cell line bv2 (bv2-st medium). |
2008-07-18 |
2023-08-12 |
mouse |
| J Kyle Krady, Hsiao-Wen Lin, Christina M Liberto, Anirban Basu, Sergey G Kremlev, Steven W Leviso. Ciliary neurotrophic factor and interleukin-6 differentially activate microglia. Journal of neuroscience research. vol 86. issue 7. 2008-07-08. PMID:18214991. |
correspondingly, conditioned media from cntf-stimulated microglia promote motor neuron survival threefold beyond controls, whereas il-6-stimulated microglia decrease neuronal survival twofold. |
2008-07-08 |
2023-08-12 |
rat |
| Emanuele Cacci, Maria Antonietta Ajmone-Cat, Tonino Anelli, Stefano Biagioni, Luisa Minghett. In vitro neuronal and glial differentiation from embryonic or adult neural precursor cells are differently affected by chronic or acute activation of microglia. Glia. vol 56. issue 4. 2008-05-30. PMID:18186084. |
acutely activated microglia, or their conditioned medium, reduced npc survival, prevented neuronal differentiation and strongly increased glial differentiation, likely through the release of proinflammatory cytokines, whereas chronically activated microglia were permissive to neuronal differentiation and cell survival, and still supported glial differentiation. |
2008-05-30 |
2023-08-12 |
Not clear |
| Mauricio A Retamal, Nicolas Froger, Nicolas Palacios-Prado, Pascal Ezan, Pablo J Sáez, Juan C Sáez, Christian Giaum. Cx43 hemichannels and gap junction channels in astrocytes are regulated oppositely by proinflammatory cytokines released from activated microglia. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 50. 2008-01-22. PMID:18077690. |
now, we demonstrate that either conditioned medium harvested from activated microglia or a mixture of these two cytokines enhances the cellular exchange with the extracellular milieu via cx43 hemichannels. |
2008-01-22 |
2023-08-12 |
mouse |
| Mauricio A Retamal, Nicolas Froger, Nicolas Palacios-Prado, Pascal Ezan, Pablo J Sáez, Juan C Sáez, Christian Giaum. Cx43 hemichannels and gap junction channels in astrocytes are regulated oppositely by proinflammatory cytokines released from activated microglia. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 50. 2008-01-22. PMID:18077690. |
indeed, unitary events of approximately 220 ps corresponding to cx43 hemichannels were much more frequent in astrocytes treated with microglia conditioned medium than under control conditions. |
2008-01-22 |
2023-08-12 |
mouse |
| Sébastien Tilleux, Julie Berger, Emmanuel Herman. Induction of astrogliosis by activated microglia is associated with a down-regulation of metabotropic glutamate receptor 5. Journal of neuroimmunology. vol 189. issue 1-2. 2007-11-28. PMID:17628702. |
to explore the impact of neuroinflammation on the control of glutamate transmission, we studied the metabotropic glutamate receptor 5 (mglur5) expression in cultured astrocytes exposed to conditioned medium from lipopolysaccharide-activated microglia. |
2007-11-28 |
2023-08-12 |
Not clear |
| Andis Klegeris, Hyun B Choi, James G McLarnon, Patrick L McGee. Functional ryanodine receptors are expressed by human microglia and THP-1 cells: Their possible involvement in modulation of neurotoxicity. Journal of neuroscience research. vol 85. issue 10. 2007-11-01. PMID:17526017. |
neurotoxicity of conditioned medium from human microglia and thp-1 monocytic cells stimulated with a combination of interferon-gamma (ifn-gamma) with either lipopolysaccharide (lps) or alpha-synuclein was diminished by dhbp. |
2007-11-01 |
2023-08-12 |
human |
| Shengzhou Wu, Anthony S Basile, Steven W Barge. Induction of serine racemase expression and D-serine release from microglia by secreted amyloid precursor protein (sAPP). Current Alzheimer research. vol 4. issue 3. 2007-10-02. PMID:17627481. |
similarly, we report here that conditioned medium from microglia treated with secreted amyloid precursor protein (sapp) contained elevated levels of d-serine. |
2007-10-02 |
2023-08-12 |
Not clear |
| Kazuyuki Nakajima, Yoko Tohyama, Shyuichi Maeda, Shinichi Kohsaka, Tadashi Kurihar. Neuronal regulation by which microglia enhance the production of neurotrophic factors for GABAergic, catecholaminergic, and cholinergic neurons. Neurochemistry international. vol 50. issue 6. 2007-07-26. PMID:17459525. |
to evaluate the neurotrophic effects of microglia stimulated with neurons, the effects of conditioned medium (cm) of microglia stimulated with neuronal cm (ncm) were assessed in neuronal cultures. |
2007-07-26 |
2023-08-12 |
rat |
| Francis C Lau, Donna F Bielinski, James A Josep. Inhibitory effects of blueberry extract on the production of inflammatory mediators in lipopolysaccharide-activated BV2 microglia. Journal of neuroscience research. vol 85. issue 5. 2007-07-18. PMID:17265471. |
results indicated that treatments with blueberry extract inhibited the production of the inflammatory mediator nitric oxide (no) as well as the cytokines interleukin-1beta and tumor necrosis factor-alpha, in cell conditioned media from lipopolysaccharide (lps)-activated bv2 microglia. |
2007-07-18 |
2023-08-12 |
Not clear |
| Asgar Zaheer, Smita Zaheer, Shailendra K Sahu, Scott Knight, Houdy Khosravi, Satya N Mathur, Ramon Li. A novel role of glia maturation factor: induction of granulocyte-macrophage colony-stimulating factor and pro-inflammatory cytokines. Journal of neurochemistry. vol 101. issue 2. 2007-06-01. PMID:17250654. |
the cell-free conditioned medium from overexpressing gmf astrocytes contained 320 +/- 33 pg/ml of gm-csf, which was responsible for enhanced production and secretion of tnf-alpha, il-1beta, il-6, and ip-10 by microglia. |
2007-06-01 |
2023-08-12 |
Not clear |
| Asgar Zaheer, Smita Zaheer, Shailendra K Sahu, Scott Knight, Houdy Khosravi, Satya N Mathur, Ramon Li. A novel role of glia maturation factor: induction of granulocyte-macrophage colony-stimulating factor and pro-inflammatory cytokines. Journal of neurochemistry. vol 101. issue 2. 2007-06-01. PMID:17250654. |
presence of these inflammatory cytokines in the conditioned medium from microglia efficiently destroyed oligodendrocytes in culture. |
2007-06-01 |
2023-08-12 |
Not clear |
| Bart R Tambuyzer, Ivo Lambrichts, Marc Lenjou, Etienne J Nouwe. Effects of the pig renal epithelial cell line LLC-PK1 and its conditioned medium on the phenotype of porcine microglia in vitro. European journal of cell biology. vol 86. issue 4. 2007-05-17. PMID:17337088. |
effects of the pig renal epithelial cell line llc-pk1 and its conditioned medium on the phenotype of porcine microglia in vitro. |
2007-05-17 |
2023-08-12 |
Not clear |
| Bart R Tambuyzer, Ivo Lambrichts, Marc Lenjou, Etienne J Nouwe. Effects of the pig renal epithelial cell line LLC-PK1 and its conditioned medium on the phenotype of porcine microglia in vitro. European journal of cell biology. vol 86. issue 4. 2007-05-17. PMID:17337088. |
moreover, the conditioned medium of the renal cells promoted proliferation of microglia, inhibited giant cell formation and stimulated microglia to retain their capability to generate superoxide and to perform phagocytosis. |
2007-05-17 |
2023-08-12 |
Not clear |
| Masaya Nakanishi, Tetsuhiro Niidome, Satoru Matsuda, Akinori Akaike, Takeshi Kihara, Hachiro Sugimot. Microglia-derived interleukin-6 and leukaemia inhibitory factor promote astrocytic differentiation of neural stem/progenitor cells. The European journal of neuroscience. vol 25. issue 3. 2007-05-02. PMID:17328769. |
to this end, nspcs and microglial cultures were obtained from rat embryonic day 16 subventricular zone (svz) and rat postnatal 1 day cortex, respectively, and the conditioned medium from microglia was prepared. |
2007-05-02 |
2023-08-12 |
rat |
| Jose L M Madrigal, Cinzia Dello Russo, Vitaliy Gavrilyuk, Douglas L Feinstei. Effects of noradrenaline on neuronal NOS2 expression and viability. Antioxidants & redox signaling. vol 8. issue 5-6. 2007-03-27. PMID:16771678. |
the authors previously showed that conditioned media (cm) from activated microglia increased inducible nitric oxide synthase (nos2) in cortical neurons. |
2007-03-27 |
2023-08-12 |
mouse |
| Claudia Röhl, Ralph Lucius, Jobst Siever. The effect of activated microglia on astrogliosis parameters in astrocyte cultures. Brain research. vol 1129. issue 1. 2007-03-22. PMID:17169340. |
to examine the involvement of activated microglia in the onset and maintenance of astrogliosis, we used an in vitro model of purified cultures of astrocytes and assessed as parameters for astrogliosis gfap, vimentin, astroglial hypertrophy and cell growth after treatment with medium conditioned by lps (lipopolysaccarides)-stimulated microglia. |
2007-03-22 |
2023-08-12 |
Not clear |
| Robert K Nuttall, Claudia Silva, Walter Hader, Amit Bar-Or, Kamala D Patel, Dylan R Edwards, V Wee Yon. Metalloproteinases are enriched in microglia compared with leukocytes and they regulate cytokine levels in activated microglia. Glia. vol 55. issue 5. 2007-03-20. PMID:17216595. |
activation of microglia also resulted in increased levels of tumor necrosis factor (tnf)-alpha, interleukin (il)-1beta, and il-10 protein in the conditioned media of cells. |
2007-03-20 |
2023-08-12 |
human |
| Li Ni, Giselles Acevedo, Bhargavi Muralidharan, Nischal Padala, Jennifer To, G Miller Jonakai. Toll-like receptor ligands and CD154 stimulate microglia to produce a factor(s) that promotes excess cholinergic differentiation in the developing rat basal forebrain: implications for neurodevelopmental disorders. Pediatric research. vol 61. issue 1. 2007-02-07. PMID:17211134. |
microglia stimulated with lipopolysaccharide (lps), peptidoglycan, poly i:c and cd154 produce conditioned media (cm) that promotes excessive numbers of cholinergic neurons and levels of choline acetyltransferase (chat) activity 6-8 times that of untreated cultures. |
2007-02-07 |
2023-08-12 |
rat |