| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Emanuele Cacci, Jan-Hendrik Claasen, Zaal Kokai. Microglia-derived tumor necrosis factor-alpha exaggerates death of newborn hippocampal progenitor cells in vitro. Journal of neuroscience research. vol 80. issue 6. 2005-08-09. PMID:15884015. |
conditioned medium from an activated microglial cell line (bv-2) had a similar effect, though conditioned medium from nonactivated microglia increased the survival of hpc. |
2005-08-09 |
2023-08-12 |
Not clear |
| Radmila Filipovic, Nada Zecevi. Lipopolysaccharide affects Golli expression and promotes proliferation of oligodendrocyte progenitors. Glia. vol 49. issue 4. 2005-05-11. PMID:15546149. |
second, golli proteins were demonstrated only in the conditioned medium from lps-treated microglial cell cultures (lps-mcm), and were absent in either the conditioned media from lps-treated astrocytes or the control media. |
2005-05-11 |
2023-08-12 |
mouse |
| Kazuyuki Nakajima, Yoko Tohyama, Tadashi Kurihara, Shinichi Kohsak. Enhancement of urokinase-type plasminogen activator (uPA) secretion, but not that of substrate plasminogen (PGn), by rat microglia stimulated with neuronal conditioned medium. Neuroscience letters. vol 378. issue 1. 2005-04-21. PMID:15763164. |
enhancement of urokinase-type plasminogen activator (upa) secretion, but not that of substrate plasminogen (pgn), by rat microglia stimulated with neuronal conditioned medium. |
2005-04-21 |
2023-08-12 |
rat |
| Kazuyuki Nakajima, Yoko Tohyama, Tadashi Kurihara, Shinichi Kohsak. Enhancement of urokinase-type plasminogen activator (uPA) secretion, but not that of substrate plasminogen (PGn), by rat microglia stimulated with neuronal conditioned medium. Neuroscience letters. vol 378. issue 1. 2005-04-21. PMID:15763164. |
assuming the presence of intercellular interactions between injured motoneurons and microglia in the axotomized facial nucleus, we investigated the effects of neuronal conditioned medium (ncm) on the release of urokinase-type plasminogen activator (upa) from microglia. |
2005-04-21 |
2023-08-12 |
rat |
| Hong Liao, Wen-yu Bu, Ting-Hua Wang, Sohail Ahmed, Zhi-Cheng Xia. Tenascin-R plays a role in neuroprotection via its distinct domains that coordinate to modulate the microglia function. The Journal of biological chemistry. vol 280. issue 9. 2005-04-07. PMID:15615725. |
interestingly, epidermal growth factor-like repeats and fibronectin 6-8 induced a dramatic up-regulation in the secretion of brain-derived neurotrophic factor/transforming growth factor-beta and nerve growth factor/transforming growth factor-beta, respectively, and conditioned medium from activated microglia was able to promote neurite outgrowth of n1e-115 cells and primary cortical neurons. |
2005-04-07 |
2023-08-12 |
Not clear |
| Kazuyuki Nakajima, Yoko Tohyama, Tadashi Kurihara, Shinichi Kohsak. Axotomy-dependent urokinase induction in the rat facial nucleus: possible stimulation of microglia by neurons. Neurochemistry international. vol 46. issue 2. 2005-03-09. PMID:15627511. |
the analysis of conditioned neuronal medium (cnm)-effects on microglia and conditioned microglial medium (cmm)-effects on neurons revealed that microglia enhance upa release in response to cnm, rather than vice versa. |
2005-03-09 |
2023-08-12 |
rat |
| Hakan Savli, M Dogan Gulkac, Nilufer Ese. The effect of stimulated microglia conditioned media on BDNF gene expression of striatal astrocytes: quantification by real-time PCR. The International journal of neuroscience. vol 114. issue 12. 2005-01-13. PMID:15512843. |
the effect of stimulated microglia conditioned media on bdnf gene expression of striatal astrocytes: quantification by real-time pcr. |
2005-01-13 |
2023-08-12 |
rat |
| Hakan Savli, M Dogan Gulkac, Nilufer Ese. The effect of stimulated microglia conditioned media on BDNF gene expression of striatal astrocytes: quantification by real-time PCR. The International journal of neuroscience. vol 114. issue 12. 2005-01-13. PMID:15512843. |
in the present study, the authors aimed to evaluate the effect of microglia conditioned medium (mcm) on brain derived neurotrophic factor (bdnf) gene expression of astrocytes by quantitative real-time polymerase chain reaction (pcr). |
2005-01-13 |
2023-08-12 |
rat |
| Hakan Savli, M Dogan Gulkac, Nilufer Ese. The effect of stimulated microglia conditioned media on BDNF gene expression of striatal astrocytes: quantification by real-time PCR. The International journal of neuroscience. vol 114. issue 12. 2005-01-13. PMID:15512843. |
astrocytes that cultured- from the striatum were incubated with conditioned medium of either zymosan a stiumulated or unstimulated microglia which were cultured from striatum and cortex of the rat pups. |
2005-01-13 |
2023-08-12 |
rat |
| Rommy von Bernhardi, Jaime Eugení. Microglial reactivity to beta-amyloid is modulated by astrocytes and proinflammatory factors. Brain research. vol 1025. issue 1-2. 2005-01-06. PMID:15464759. |
this pro-apoptotic effect was not observed in hippocampal cultures exposed to conditioned media obtained from mixed glial (astrocytes and microglia) cultures that had been exposed to abeta. |
2005-01-06 |
2023-08-12 |
Not clear |
| Bhooma Srinivasan, Criselda H Roque, Barbara L Hempstead, Muayyad R Al-Ubaidi, Rouel S Roqu. Microglia-derived pronerve growth factor promotes photoreceptor cell death via p75 neurotrophin receptor. The Journal of biological chemistry. vol 279. issue 40. 2004-11-15. PMID:15277529. |
conditioned media from cultured retinal microglia (mgcm) consistently yielded a approximately 32-kda ngf-reactive band when supplemented with bovine serum albumin (bsa) or protease inhibitors (pi); and promoted cell death that was suppressed by ngf immunodepletion in a mouse photoreceptor cell line (661w). |
2004-11-15 |
2023-08-12 |
mouse |
| Shuuitsu Tanaka, Tatsuro Koik. Selective inflammatory stimulations enhance release of microglial response factor (MRF)-1 from cultured microglia. Glia. vol 40. issue 3. 2003-08-01. PMID:12420315. |
we also showed that a conditioned medium from cerebellar granule neurons undergoing apoptosis markedly increased mrf-1 release from microglia; that effect was significantly inhibited by oatp. |
2003-08-01 |
2023-08-12 |
rat |
| Gerald Münch, Jovana Gasic-Milenkovic, Sladjana Dukic-Stefanovic, Björn Kuhla, Katrin Heinrich, Peter Riederer, Henri J Huttunen, Hank Founds, Gangadharan Sajithla. Microglial activation induces cell death, inhibits neurite outgrowth and causes neurite retraction of differentiated neuroblastoma cells. Experimental brain research. vol 150. issue 1. 2003-07-16. PMID:12698210. |
at high lps or age concentrations, conditioned medium from microglia caused neuronal cell death in a dose-dependent manner. |
2003-07-16 |
2023-08-12 |
Not clear |
| Claudia Rozenfeld, Rodrigo Martinez, Rodrigo T Figueiredo, Marcelo T Bozza, Flávia R S Lima, Ana Lúcia Pires, Patrícia M Silva, Adriana Bonomo, Joseli Lannes-Vieira, Wanderley De Souza, Vivaldo Moura-Net. Soluble factors released by Toxoplasma gondii-infected astrocytes down-modulate nitric oxide production by gamma interferon-activated microglia and prevent neuronal degeneration. Infection and immunity. vol 71. issue 4. 2003-05-12. PMID:12654825. |
in this work, we describe a significant down-modulation of no production by ifn-gamma-activated microglia in the presence of conditioned medium of t. gondii-infected astrocytes (cmi). |
2003-05-12 |
2023-08-12 |
Not clear |
| Deanna L Taylor, Lara T Diemel, Jennifer M Pococ. Activation of microglial group III metabotropic glutamate receptors protects neurons against microglial neurotoxicity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 6. 2003-04-17. PMID:12657674. |
similar results were obtained with microglial conditioned medium or in coculture, suggesting that the activation of microglial group iii mglu receptors may modulate the production of stable neurotoxins from the microglia. |
2003-04-17 |
2023-08-12 |
rat |
| Sheila M Brooke, Robert M Sapolsk. Glucocorticoid exacerbation of gp120 neurotoxicity: role of microglia. Experimental neurology. vol 177. issue 1. 2002-12-09. PMID:12429218. |
twenty-four-hour exposure of microglia to gcs decreased the toxicity of gp120-treated microglial conditioned media. |
2002-12-09 |
2023-08-12 |
Not clear |
| R S Nicholas, S Stevens, M G Wing, D A Compsto. Microglia-derived IGF-2 prevents TNFalpha induced death of mature oligodendrocytes in vitro. Journal of neuroimmunology. vol 124. issue 1-2. 2002-05-02. PMID:11958820. |
insulin-like growth factor-2 (igf-2) present in media conditioned by non-activated and interferon gamma (ifn gamma)-treated microglia reduces galactocerebroside(+) (galc) oligodendrocyte apoptosis in cultures derived both from the cg4 cell line and primary rat cortices. |
2002-05-02 |
2023-08-12 |
rat |
| K Nakajima, S Honda, Y Tohyama, Y Imai, S Kohsaka, T Kurihar. Neurotrophin secretion from cultured microglia. Journal of neuroscience research. vol 65. issue 4. 2001-09-13. PMID:11494368. |
rat primary microglia were found to constitutively secrete a limited amount of brain-derived neurotrophic factor (bdnf), but nerve growth factor (ngf) and neurotrophin-3 (nt-3) were undetectable in the conditioned medium. |
2001-09-13 |
2023-08-12 |
rat |
| R S Nicholas, M G Wing, A Compsto. Nonactivated microglia promote oligodendrocyte precursor survival and maturation through the transcription factor NF-kappa B. The European journal of neuroscience. vol 13. issue 5. 2001-07-12. PMID:11264668. |
media conditioned by nonactivated microglia increase the number of surviving galactocerebroside(+) (galc(+)) oligodendrocytes in vitro at 48 h by inhibiting the apoptosis of opcs and stimulating their maturation to galc+ oligodendrocytes. |
2001-07-12 |
2023-08-12 |
rat |
| R S Nicholas, M G Wing, A Compsto. Nonactivated microglia promote oligodendrocyte precursor survival and maturation through the transcription factor NF-kappa B. The European journal of neuroscience. vol 13. issue 5. 2001-07-12. PMID:11264668. |
these effects are not observed with medium conditioned by microglia activated with interferon-gamma (ifn-gamma). |
2001-07-12 |
2023-08-12 |
rat |