All Relations between conditioned response and microglial cell

Publication Sentence Publish Date Extraction Date Species
R S Nicholas, M G Wing, A Compsto. Nonactivated microglia promote oligodendrocyte precursor survival and maturation through the transcription factor NF-kappa B. The European journal of neuroscience. vol 13. issue 5. 2001-07-12. PMID:11264668. conditioned medium from nonactivated microglia is associated with upregulation in opcs of nuclear factor of kappa binding (nf-kappa b) p65 subunit. 2001-07-12 2023-08-12 rat
R S Nicholas, M G Wing, A Compsto. Nonactivated microglia promote oligodendrocyte precursor survival and maturation through the transcription factor NF-kappa B. The European journal of neuroscience. vol 13. issue 5. 2001-07-12. PMID:11264668. the use of antisense to the inhibitor of kappa binding (i kappa b) induces p65 subunit activation in opcs and, in common with medium conditioned by nonactivated microglia, also inhibits opc apoptosis and promotes cell maturation. 2001-07-12 2023-08-12 rat
R S Nicholas, M G Wing, A Compsto. Nonactivated microglia promote oligodendrocyte precursor survival and maturation through the transcription factor NF-kappa B. The European journal of neuroscience. vol 13. issue 5. 2001-07-12. PMID:11264668. anti-platelet-derived growth factor (pdgf) antibody abolishes this effect even though pdgf-a chain is expressed at similar levels within both nonactivated and ifn-gamma-activated microglia and both conditioned media have similar levels of pdgf-a chain bioactivity. 2001-07-12 2023-08-12 rat
R S Nicholas, M G Wing, A Compsto. Nonactivated microglia promote oligodendrocyte precursor survival and maturation through the transcription factor NF-kappa B. The European journal of neuroscience. vol 13. issue 5. 2001-07-12. PMID:11264668. however, only conditioned medium from nonactivated microglia recruit phosphatidyl-3-inositol (pi-3) kinase to the pdgf-alpha receptor and synergise with endogenous pdgf-a chain to increase nf-kappa b activation. 2001-07-12 2023-08-12 rat
R S Nicholas, A Compston, D R Brow. Inhibition of tumour necrosis factor-alpha (TNFalpha)-induced NF-kappaB p52 converts the metabolic effects of microglial-derived TNFalpha on mouse cerebellar neurones to neurotoxicity. Journal of neurochemistry. vol 76. issue 5. 2001-04-05. PMID:11238728. here, we demonstrate that media conditioned by interferon-gamma treated microglia initially impair the metabolism of mouse cerebellar neurones grown in serum-free conditions without inducing cell death. 2001-04-05 2023-08-12 mouse
R S Nicholas, A Compston, D R Brow. Inhibition of tumour necrosis factor-alpha (TNFalpha)-induced NF-kappaB p52 converts the metabolic effects of microglial-derived TNFalpha on mouse cerebellar neurones to neurotoxicity. Journal of neurochemistry. vol 76. issue 5. 2001-04-05. PMID:11238728. these effects are blocked by antibodies to tumour necrosis factor-alpha (tnfalpha), a cytokine produced by microglial activation, and they are not reproduced by media conditioned by resting microglia. 2001-04-05 2023-08-12 mouse
R S Nicholas, A Compston, D R Brow. Inhibition of tumour necrosis factor-alpha (TNFalpha)-induced NF-kappaB p52 converts the metabolic effects of microglial-derived TNFalpha on mouse cerebellar neurones to neurotoxicity. Journal of neurochemistry. vol 76. issue 5. 2001-04-05. PMID:11238728. between 2 and 48 h tnfalpha present in media conditioned by interferon-gamma treated but not resting microglia is associated with nuclear factor kappa b (nf-kappab) consensus sequence binding in paired mouse cerebellar neuronal cultures without affecting activation of the signal transducer and activator of transcription (stat) transcription factor. 2001-04-05 2023-08-12 mouse
P J Kingham, J M Pococ. Microglial secreted cathepsin B induces neuronal apoptosis. Journal of neurochemistry. vol 76. issue 5. 2001-04-05. PMID:11238732. conditioned medium from cga exposed microglia was neurotoxic to the ht22 hippocampal cell line and to primary cultures of cerebellar granule neurones. 2001-04-05 2023-08-12 Not clear
P J Kingham, J M Pococ. Microglial secreted cathepsin B induces neuronal apoptosis. Journal of neurochemistry. vol 76. issue 5. 2001-04-05. PMID:11238732. conditioned medium from activated microglia or cathepsin b alone induced neuronal apoptosis and caspase 3 activation. 2001-04-05 2023-08-12 Not clear
S W Barger, A S Basil. Activation of microglia by secreted amyloid precursor protein evokes release of glutamate by cystine exchange and attenuates synaptic function. Journal of neurochemistry. vol 76. issue 3. 2001-03-15. PMID:11158256. conditioned medium from primary rat microglia activated by sapp caused a calcium elevation in hippocampal neurons, whereas medium from untreated microglia did not. 2001-03-15 2023-08-12 rat
Y Pang, Z Cai, P G Rhode. Effects of lipopolysaccharide on oligodendrocyte progenitor cells are mediated by astrocytes and microglia. Journal of neuroscience research. vol 62. issue 4. 2000-12-14. PMID:11070494. when o-2a progenitor cells were cultured in the conditioned medium obtained from either astrocyte or microglial cell cultures for 48 hr, survival rate and differentiation of o-2a cells into mature oligodendrocytes were greatly enhanced as measured by the mtt assay and immunocytochemistry. 2000-12-14 2023-08-12 rat
Y Pang, Z Cai, P G Rhode. Effects of lipopolysaccharide on oligodendrocyte progenitor cells are mediated by astrocytes and microglia. Journal of neuroscience research. vol 62. issue 4. 2000-12-14. PMID:11070494. the conditioned medium obtained from astrocytes or microglia treated with lps for 48 hr, however, failed to show such a promotional effect on viability and differentiation of o-2a cells. 2000-12-14 2023-08-12 rat
Y Pang, Z Cai, P G Rhode. Effects of lipopolysaccharide on oligodendrocyte progenitor cells are mediated by astrocytes and microglia. Journal of neuroscience research. vol 62. issue 4. 2000-12-14. PMID:11070494. when 5 microg/ml lps was used to stimulate astrocytes or microglia, the conditioned medium from these glial cell cultures caused o-2a cell injury. 2000-12-14 2023-08-12 rat
M P Flavin, G Zhao, L T H. Microglial tissue plasminogen activator (tPA) triggers neuronal apoptosis in vitro. Glia. vol 29. issue 4. 2000-04-11. PMID:10652444. we previously showed that conditioned medium (cm) harvested from peritoneal macrophages or from activated microglia triggered apoptosis in rat hippocampal neurons in culture. 2000-04-11 2023-08-12 human
G M Jonakait, Y Wen, Y Wan, L N. Macrophage cell-conditioned medium promotes cholinergic differentiation of undifferentiated progenitors and synergizes with nerve growth factor action in the developing basal forebrain. Experimental neurology. vol 161. issue 1. 2000-03-23. PMID:10683294. conditioned medium from stimulated microglia and from the monocyte/macrophage cell line (raw 264.7; mc-cm) promotes the differentiation of cholinergic neurons from undifferentiated progenitors in the septal nuclei and adjacent basal forebrain (bf). 2000-03-23 2023-08-12 rat
M E Smith, M T Hoerne. Astrocytes modulate macrophage phagocytosis of myelin in vitro. Journal of neuroimmunology. vol 102. issue 2. 2000-01-27. PMID:10636484. while microglia were also stimulated by conditioned medium, adhesion to astrocytes or matrigel induced a downregulation in phagocytic activity. 2000-01-27 2023-08-12 Not clear
S A South, G E Deibler, S F Tzeng, A Badache, M G Kirchner, N Muja, G H De Vrie. Myelin basic protein (MBP) and MBP peptides are mitogens for cultured astrocytes. Glia. vol 29. issue 1. 2000-01-18. PMID:10594925. the mitogenic effect of these individual peptides was potentiated by simultaneous treatment with microglia conditioned media (cm). 2000-01-18 2023-08-12 Not clear
R B Meeker, Y Azuma, D C Bragg, R V English, M Tompkin. Microglial proliferation in cortical neural cultures exposed to feline immunodeficiency virus. Journal of neuroimmunology. vol 101. issue 1. 1999-12-09. PMID:10580809. conditioned medium from astrocytes or mixed neural cultures treated with feline immunodeficiency virus stimulated the proliferation of purified microglia. 1999-12-09 2023-08-12 human
Y Persidsky, A Ghorpade, J Rasmussen, J Limoges, X J Liu, M Stins, M Fiala, D Way, K S Kim, M H Witte, M Weinand, L Carhart, H E Gendelma. Microglial and astrocyte chemokines regulate monocyte migration through the blood-brain barrier in human immunodeficiency virus-1 encephalitis. The American journal of pathology. vol 155. issue 5. 1999-11-30. PMID:10550317. pure cultures of virus-infected and activated microglia or astrocytes exposed to microglial conditioned media produced significant quantities of beta-chemokines. 1999-11-30 2023-08-12 mouse
K A Young, W D Hirst, E Solito, G P Wilki. De novo expression of lipocortin-1 in reactive microglia and astrocytes in kainic acid lesioned rat cerebellum. Glia. vol 26. issue 4. 1999-09-09. PMID:10383052. lc-1 was detected in microglial but not astrocytic, conditioned media, confirming the in vivo observations that activated microglia may secrete lc-1. 1999-09-09 2023-08-12 rat