| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sara Merlo, Simona Federica Spampinato, Martina Beneventano, Maria Angela Sortin. The contribution of microglia to early synaptic compensatory responses that precede β-amyloid-induced neuronal death. Scientific reports. vol 8. issue 1. 2019-10-14. PMID:29740062. |
conditioned media from resting (cmc) or aβ42-treated (cma) microglia were tested for their effects on synaptophysin expression in sh-sy5y neuronal-like cells during challenge with aβ42. |
2019-10-14 |
2023-08-13 |
rat |
| Xin Ge, Dong-Mei Zhang, Meng-Meng Li, Yi Zhang, Xiang-Yang Zhu, Yong Zhou, Xiao Peng, Ai-Guo She. Microglial LOX-1/MAPKs/NF-κB positive loop promotes the vicious cycle of neuroinflammation and neural injury. International immunopharmacology. vol 70. 2019-08-13. PMID:30807932. |
furthermore, utilizing the conditioned medium of activated microglia (mg-cm), we discovered microglial lox-1 aggravated the neuroinflammation-induced neuronal apoptosis. |
2019-08-13 |
2023-08-13 |
Not clear |
| Xiao-Hua Sun, Ming-Fen Song, Hai-Dong Song, Yu-Wen Wang, Ming-Jin Luo, Li-Ming Yi. miR‑155 mediates inflammatory injury of hippocampal neuronal cells via the activation of microglia. Molecular medicine reports. vol 19. issue 4. 2019-08-01. PMID:30720115. |
furthermore, conditioned medium from mir‑155‑treated microglia decreased the cell viability of ht22 hippocampal cells. |
2019-08-01 |
2023-08-13 |
Not clear |
| Dafina M Angelova, David R Brow. Model Senescent Microglia Induce Disease Related Changes in α-Synuclein Expression and Activity. Biomolecules. vol 8. issue 3. 2019-05-29. PMID:30071596. |
we have shown that conditioned medium from our model dystrophic microglia increases α-synuclein transcription and expression via tumor necrosis factor alpha (tnfα) and mediated through nuclear factor kappa-light-chain-enhancer of activated b cells (nf-κb). |
2019-05-29 |
2023-08-13 |
mouse |
| Marta Rodríguez-Arias, Sandra Montagud-Romero, Ana María Guardia Carrión, Carmen Ferrer-Pérez, Ana Pérez-Villalba, Eva Marco, Meritxell López Gallardo, María-Paz Viveros, José Miñarr. Social stress during adolescence activates long-term microglia inflammation insult in reward processing nuclei. PloS one. vol 13. issue 10. 2019-04-03. PMID:30365534. |
in addition to an increase in the conditioned rewarding effects of cocaine, our results showed that rsd in adolescence produced inflammatory reactivity in microglia that is prolonged into adulthood, affecting astrocytes and neurons of two reward-processing areas of the brain (the prelimbic cortex, and the nucleus accumbens core). |
2019-04-03 |
2023-08-13 |
Not clear |
| Takeshi K Matsui, Eiichiro Mor. Microglia support neural stem cell maintenance and growth. Biochemical and biophysical research communications. vol 503. issue 3. 2019-04-01. PMID:30098787. |
we cultured adult mouse-derived nspcs in a conditioned medium from bv2 immortalized microglia without growth factors and evaluated their differentiation. |
2019-04-01 |
2023-08-13 |
Not clear |
| Takeshi K Matsui, Eiichiro Mor. Microglia support neural stem cell maintenance and growth. Biochemical and biophysical research communications. vol 503. issue 3. 2019-04-01. PMID:30098787. |
moreover, conditioned media from m2-polarized primary microglia, stimulated by il-10/il-13, showed supportive effect on nspc proliferation. |
2019-04-01 |
2023-08-13 |
Not clear |
| Miriam Scheld, Athanassios Fragoulis, Stella Nyamoya, Adib Zendedel, Bernd Denecke, Barbara Krauspe, Nico Teske, Markus Kipp, Cordian Beyer, Tim Clarne. Mitochondrial Impairment in Oligodendroglial Cells Induces Cytokine Expression and Signaling. Journal of molecular neuroscience : MN. vol 67. issue 2. 2019-02-19. PMID:30547416. |
in vitro, conditioned medium of stressed oligodendroglial cells triggered the activation of microglia cells. |
2019-02-19 |
2023-08-13 |
mouse |
| Bin Hui, Liping Zhang, Qinhua Zhou, Ling Hu. Pristimerin Inhibits LPS-Triggered Neurotoxicity in BV-2 Microglia Cells Through Modulating IRAK1/TRAF6/TAK1-Mediated NF-κB and AP-1 Signaling Pathways In Vitro. Neurotoxicity research. vol 33. issue 2. 2019-01-31. PMID:29119451. |
pristimerin also significantly inhibited migration of bv-2 microglia and alleviated the death of neuron-like pc12 cell induced by the conditioned medium from lps-activated bv-2 microglial cells. |
2019-01-31 |
2023-08-13 |
Not clear |
| Bing Zhao, Hao Wang, Cai-Xia Li, Sheng-Wen Song, San-Hua Fang, Er-Qing Wei, Qiao-Juan Sh. GPR17 mediates ischemia-like neuronal injury via microglial activation. International journal of molecular medicine. vol 42. issue 5. 2019-01-21. PMID:30226562. |
finally, the results demonstrated that the conditioned medium of microglia pretreated with ogd/r induced neuronal death, and the neuronal injury was significantly inhibited by gpr17 knockdown. |
2019-01-21 |
2023-08-13 |
Not clear |
| H Wolfe, A M Minogue, S Rooney, M A Lync. Infiltrating macrophages contribute to age-related neuroinflammation in C57/BL6 mice. Mechanisms of ageing and development. vol 173. 2018-11-14. PMID:29758231. |
we sought to determine whether macrophages might trigger microglial activation and the evidence shows that conditioned medium obtained from interferon-γ (ifnγ)-stimulated macrophages potently activated microglia. |
2018-11-14 |
2023-08-13 |
mouse |
| Ziyun Jiang, Qin Song, Mingliang Tang, Lingyan Yang, Yilin Cheng, Min Zhang, Dongsheng Xu, Guosheng Chen. Enhanced Migration of Neural Stem Cells by Microglia Grown on a Three-Dimensional Graphene Scaffold. ACS applied materials & interfaces. vol 8. issue 38. 2018-10-23. PMID:27589088. |
in this study, we used a combination of immunofluorescence, western blotting, enzyme-linked immunosorbent assays, and scanning electron microscopy to investigate how conditioned medium (cm) produced from microglia grown on two-dimensional graphene (2d-g) films or three-dimensional graphene (3d-g) foams govern nsc migration. |
2018-10-23 |
2023-08-13 |
Not clear |
| Bingxu Huang, Dewei He, Guangxin Chen, Xin Ran, Wenjin Guo, Xingchi Kan, Wei Wang, Dianfeng Liu, Shoupeng Fu, Juxiong Li. α-Cyperone inhibits LPS-induced inflammation in BV-2 cells through activation of Akt/Nrf2/HO-1 and suppression of the NF-κB pathway. Food & function. vol 9. issue 5. 2018-10-03. PMID:29667667. |
moreover, the toxicities of conditioned medium from activated microglia toward dopaminergic neuronal sh-sy5y cells and hippocampal neuronal ht22 cells were significantly inhibited by pretreatment with α-cyperone. |
2018-10-03 |
2023-08-13 |
Not clear |
| Zhiqian Yu, Hotaka Fukushima, Chiaki Ono, Mai Sakai, Yoshiyuki Kasahara, Yoshie Kikuchi, Nicole Gunawansa, Yuta Takahashi, Hiroo Matsuoka, Satoshi Kida, Hiroaki Tomit. Microglial production of TNF-alpha is a key element of sustained fear memory. Brain, behavior, and immunity. vol 59. 2018-08-23. PMID:27562421. |
expression levels of m1- and m2-type microglial marker molecules in microglia isolated from each conditioned mice group were assessed by real-time pcr and immunohistochemistry. |
2018-08-23 |
2023-08-13 |
mouse |
| Ruinan Gu, Fali Zhang, Gang Chen, Chaojun Han, Jay Liu, Zhaoxiang Ren, Yi Zhu, John L Waddington, Long Tai Zheng, Xuechu Zhe. Clk1 deficiency promotes neuroinflammation and subsequent dopaminergic cell death through regulation of microglial metabolic reprogramming. Brain, behavior, and immunity. vol 60. 2018-08-16. PMID:27769915. |
the increase in neuronal cell death was observed following treatment with conditioned media from clk1 deficient microglia. |
2018-08-16 |
2023-08-13 |
Not clear |
| A R Jayakumar, M Taherian, K S Panickar, N Shamaladevi, M E Rodriguez, B G Price, M D Norenber. Differential Response of Neural Cells to Trauma-Induced Swelling In Vitro. Neurochemical research. vol 43. issue 2. 2018-08-16. PMID:29150743. |
conditioned medium (cm) from traumatized astrocytes had no effect on neuronal swelling post-trauma, while cm from traumatized neurons and microglia potentiated the effect of trauma on astrocyte swelling. |
2018-08-16 |
2023-08-13 |
Not clear |
| Xue Fang, Dingya Sun, Zhihong Wang, Zhongwang Yu, Weili Liu, Yingyan Pu, Dan Wang, Aijun Huang, Mingdong Liu, Zhenghua Xiang, Cheng He, Li Ca. MiR-30a Positively Regulates the Inflammatory Response of Microglia in Experimental Autoimmune Encephalomyelitis. Neuroscience bulletin. vol 33. issue 6. 2018-07-24. PMID:28717866. |
in vitro, the conditioned supernatant of mouse microglia overexpressing mir-30a promoted the apoptosis of oligodendrocyte precursor cells (opcs), and inhibited opc differentiation. |
2018-07-24 |
2023-08-13 |
mouse |
| Jie Yin, Wen-Qin Xu, Ming-Xiang Ye, Yong Zhang, Hai-Yan Wang, Jian Zhang, Yu Li, Yu-Sheng Wan. Up-regulated basigin-2 in microglia induced by hypoxia promotes retinal angiogenesis. Journal of cellular and molecular medicine. vol 21. issue 12. 2018-07-11. PMID:28661035. |
in vitro, conditioned media from microglia bv2 under hypoxia treatment increase migration and tube formation of retinal capillary endothelia cells, compared with media from normoxic condition. |
2018-07-11 |
2023-08-13 |
mouse |
| Yunhui Chen, Shuguang Yu, Qiaofeng Wu, Yong Tang, Cen Jiang, Zhiqi Zhuang, Na Zhao, Biao Huang, Lushuang Xi. [Effect of bone marrow mesenchymal stem cells conditioned medium on microglia and its secretion of arginase 1 in rats]. Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery. vol 31. issue 12. 2018-06-04. PMID:29806395. |
[effect of bone marrow mesenchymal stem cells conditioned medium on microglia and its secretion of arginase 1 in rats]. |
2018-06-04 |
2023-08-13 |
rat |
| Yunhui Chen, Shuguang Yu, Qiaofeng Wu, Yong Tang, Cen Jiang, Zhiqi Zhuang, Na Zhao, Biao Huang, Lushuang Xi. [Effect of bone marrow mesenchymal stem cells conditioned medium on microglia and its secretion of arginase 1 in rats]. Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery. vol 31. issue 12. 2018-06-04. PMID:29806395. |
to observe the effect of bone marrow mesenchymal stem cells (bmscs) conditioned medium on microglia (mgs) and its secretion of arginase 1 (arg1). |
2018-06-04 |
2023-08-13 |
rat |