| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Isabel Lastres-Becker, Francisco Molina-Holgado, José A Ramos, Raphael Mechoulam, Javier Fernández-Rui. Cannabinoids provide neuroprotection against 6-hydroxydopamine toxicity in vivo and in vitro: relevance to Parkinson's disease. Neurobiology of disease. vol 19. issue 1-2. 2005-07-12. PMID:15837565. |
however, this effect was significantly lesser when the cannabinoid was directly added to neuronal cultures than when these cultures were exposed to conditioned medium obtained from mixed glial cell cultures treated with hu-210, suggesting that the cannabinoid exerted its major protective effect by regulating glial influence to neurons. |
2005-07-12 |
2023-08-12 |
mouse |
| Alastair Wilkins, Alastair Compsto. Trophic factors attenuate nitric oxide mediated neuronal and axonal injury in vitro: roles and interactions of mitogen-activated protein kinase signalling pathways. Journal of neurochemistry. vol 92. issue 6. 2005-04-22. PMID:15748166. |
oligodendrocyte conditioned medium (ocm) and insulin-like growth factor type-1 (igf-1), but not glial cell line-derived neurotrophic factor (gdnf), improved survival of neurones exposed to no donors. |
2005-04-22 |
2023-08-12 |
rat |
| Clovis Rakotoarivelo, Didier Petite, Sophie Lambard, Christine Fabre, Caroline Rouleau, Serge Lumbroso, Jan de Weille, Alain Privat, Serge Carreau, Marcel Merse. Receptors to steroid hormones and aromatase are expressed by cultured motoneurons but not by glial cells derived from rat embryo spinal cord. Neuroendocrinology. vol 80. issue 5. 2005-04-01. PMID:15677879. |
we optimized the culture parameters and found that simple addition of rat muscle extract (me) and conditioned culture medium (cm) from glial cell lines (gcl) derived from spinal cord were sufficient to obtain almost pure mn cultures. |
2005-04-01 |
2023-08-12 |
rat |
| Yumi Kaneko, Masaki Ichikawa, Yasuo Kurimoto, Kouichi Ohta, Nagahisa Yoshimur. Neuronal differentiation of hippocampus-derived neural stem cells cultured in conditioned medium of embryonic rat retina. Ophthalmic research. vol 35. issue 5. 2003-11-03. PMID:12920340. |
to investigate whether conditioned medium from embryonic rat retinas can induce differentiation of adult rat hippocampus-derived neural stem cells (ahscs) into neurons and glia in vitro. |
2003-11-03 |
2023-08-12 |
rat |
| Hugo F Carrer, María J Cambiass. Sexual differentiation of the brain: genes, estrogen, and neurotrophic factors. Cellular and molecular neurobiology. vol 22. issue 5-6. 2003-08-13. PMID:12585676. |
estrogen added to media conditioned by target glia modified the number of primary neurites and the growth of axons of hypothalamic neurons of males but not of females. |
2003-08-13 |
2023-08-12 |
Not clear |
| Marcin Gierdalski, Sharon L Julian. Influence of radial glia and Cajal-Retzius cells in neuronal migration. Results and problems in cell differentiation. vol 39. 2003-04-07. PMID:12353469. |
recently, we found that conditioned medium obtained from normal organotypic cultures returned radial glia toward their normal morphology only in a fraction of 30-50 kda molecular weight (mw). |
2003-04-07 |
2023-08-12 |
Not clear |
| Hong Guo, Zhongshu Tang, Yi Yu, Lei Xu, Guozhang Jin, Jiawei Zho. Apomorphine induces trophic factors that support fetal rat mesencephalic dopaminergic neurons in cultures. The European journal of neuroscience. vol 16. issue 10. 2003-03-05. PMID:12453049. |
increased mrna expression levels of brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor were also found in the apomorphine-treated mesencephalic cells along with concomitant protein expression increases in the conditioned medium. |
2003-03-05 |
2023-08-12 |
rat |
| A Rojo, M A Mena-Gómez, A Blázquez, M J Casarejos, A Fontán-Barreiro, J G de Yébene. [Glia conditioned medium offers protection against the toxicity induced by 6-OH-dopamine in vivo]. Revista de neurologia. vol 34. issue 12. 2003-01-16. PMID:12134273. |
[glia conditioned medium offers protection against the toxicity induced by 6-oh-dopamine in vivo]. |
2003-01-16 |
2023-08-12 |
Not clear |
| A Rojo, M A Mena-Gómez, A Blázquez, M J Casarejos, A Fontán-Barreiro, J G de Yébene. [Glia conditioned medium offers protection against the toxicity induced by 6-OH-dopamine in vivo]. Revista de neurologia. vol 34. issue 12. 2003-01-16. PMID:12134273. |
glia conditioned medium (gcm) is neurotrophic for dopaminergic (da) neurons and protects against mpp+ toxicity in vitro. |
2003-01-16 |
2023-08-12 |
Not clear |
| E Willbold, A Rothermel, J Huhn, M Reinicke, P G Laye. Cerebellar glia cells induce a correct laminar organization in chicken retinal reaggregates. Cells, tissues, organs. vol 169. issue 2. 2001-08-09. PMID:11399850. |
however, when these spheres are cultured in the presence of conditioned media derived from monolayers of cerebellar glia cells, the reassembling retinal cells behave totally differently. |
2001-08-09 |
2023-08-12 |
chicken |
| E Willbold, A Rothermel, J Huhn, M Reinicke, P G Laye. Cerebellar glia cells induce a correct laminar organization in chicken retinal reaggregates. Cells, tissues, organs. vol 169. issue 2. 2001-08-09. PMID:11399850. |
conditioned media from fibroblasts, other glia cells (except müller cells) or a set of already characterized retinogenetic factors are not able to produce this dramatic transformation. |
2001-08-09 |
2023-08-12 |
chicken |
| E Willbold, A Rothermel, J Huhn, M Reinicke, P G Laye. Cerebellar glia cells induce a correct laminar organization in chicken retinal reaggregates. Cells, tissues, organs. vol 169. issue 2. 2001-08-09. PMID:11399850. |
reaggregating cells from the chick cerebellum also form spheroids; however, neither in the presence of cerebellar glia cell-derived conditioned medium nor their control counterparts are they able to reassemble histotypically. |
2001-08-09 |
2023-08-12 |
chicken |
| K E Belmonte, L A McKinnon, N M Nathanso. Developmental expression of muscarinic acetylcholine receptors in chick retina: selective induction of M2 muscarinic receptor expression in ovo by a factor secreted by muller glial cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 22. 2001-02-22. PMID:11069949. |
we show that the m(2)-inducing activity, which we tentatively have called maria (muscarinic acetylcholine receptor-inducing activity) is produced by müller glial cells in culture, because significant activity can be found in media conditioned by essentially neuron-free cultures of müller glia, as well as by a müller glial cell line but not several neuroblastoma cell lines. |
2001-02-22 |
2023-08-12 |
chicken |
| Y Pang, Z Cai, P G Rhode. Effects of lipopolysaccharide on oligodendrocyte progenitor cells are mediated by astrocytes and microglia. Journal of neuroscience research. vol 62. issue 4. 2000-12-14. PMID:11070494. |
when 5 microg/ml lps was used to stimulate astrocytes or microglia, the conditioned medium from these glial cell cultures caused o-2a cell injury. |
2000-12-14 |
2023-08-12 |
rat |
| F Gallo, M C Morale, V Spina-Purrello, C Tirolo, N Testa, Z Farinella, R Avola, A Beaudet, B Marchett. Basic fibroblast growth factor (bFGF) acts on both neurons and glia to mediate the neurotrophic effects of astrocytes on LHRH neurons in culture. Synapse (New York, N.Y.). vol 36. issue 4. 2000-06-06. PMID:10819902. |
conditioned medium of young glia (acm-y) induced significant neurotrophic and functional effects on gt(1-1) cells, but these effects were 50% less potent than the coculture itself. |
2000-06-06 |
2023-08-12 |
Not clear |
| M M Daadi, S Weis. Generation of tyrosine hydroxylase-producing neurons from precursors of the embryonic and adult forebrain. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 11. 1999-06-16. PMID:10341249. |
th was successfully induced in all of these cell types by 24 hr exposure to basic fibroblast growth factor (fgf2) and glial cell conditioned media (cm). |
1999-06-16 |
2023-08-12 |
Not clear |
| E Iwata-Ichikawa, Y Kondo, I Miyazaki, M Asanuma, N Ogaw. Glial cells protect neurons against oxidative stress via transcriptional up-regulation of the glutathione synthesis. Journal of neurochemistry. vol 72. issue 6. 1999-06-14. PMID:10349842. |
we also examined the mechanisms of the neuroprotective effects of glial cells using a glia conditioned medium. |
1999-06-14 |
2023-08-12 |
rat |
| E Iwata-Ichikawa, Y Kondo, I Miyazaki, M Asanuma, N Ogaw. Glial cells protect neurons against oxidative stress via transcriptional up-regulation of the glutathione synthesis. Journal of neurochemistry. vol 72. issue 6. 1999-06-14. PMID:10349842. |
neurons maintained in glia conditioned medium up-regulated the level of tre-binding activity, gamma-glutamylcysteine synthetase mrna expression, and total glutathione content in response to 6-ohda or h2o2, and became more resistant to both agents than cells maintained in a normal medium. |
1999-06-14 |
2023-08-12 |
rat |
| F Féron, A Mackay-Sim, J L Andrieu, K I Matthaei, A Holley, G Sicar. Stress induces neurogenesis in non-neuronal cell cultures of adult olfactory epithelium. Neuroscience. vol 88. issue 2. 1999-06-01. PMID:10197776. |
we show here that differentiated olfactory sensory neurons arise after biochemical or mechanical stress of rat and mouse olfactory epithelial cell cultures in the absence of growth factors, complex media (e.g., serum, conditioned media, pituitary and hypothalamic extracts), or other cells (e.g., explants, feeder layers of glia, or other non-epithelial cells). |
1999-06-01 |
2023-08-12 |
mouse |
| J Engel. Spatial and temporal growth factor influences on developing midbrain dopaminergic neurons. Journal of neuroscience research. vol 53. issue 4. 1998-10-28. PMID:9710260. |
in e15 mesencephalic cultures, the number of surviving tyrosine hydroxylase-immunoreactive dopaminergic neurons maximally increased 2.6-fold with medium conditioned by glia of the e15-e20 mesencephalon, the e17-e20 striatum, or the e20 cortex. |
1998-10-28 |
2023-08-12 |
rat |