| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Amir, J Stewar. Induction of Fos expression in the circadian system by unsignaled light is attenuated as a result of previous experience with signaled light: a role for Pavlovian conditioning. Neuroscience. vol 83. issue 3. 1998-04-02. PMID:9483549. |
we suspected that once the mechanism mediating fos expression in the suprachiasmatic nucleus had become tuned to receiving light signaled by a conditioned stimulus, the response to presentation of light alone would be diminished. |
1998-04-02 |
2023-08-12 |
Not clear |
| L Cervo, R Samani. Effects of dopaminergic and glutamatergic receptor antagonists on the establishment and expression of conditioned locomotion to cocaine in rats. Brain research. vol 731. issue 1-2. 1997-03-25. PMID:8883851. |
the d1-receptor antagonist sch 23390 attenuated the expression of cocaine-induced conditioned locomotion whereas the lower dose (0.03 mg/kg i.p.) |
1997-03-25 |
2023-08-12 |
rat |
| R Ranaldi, R J Beninge. Bromocriptine enhancement of responding for conditioned reward depends on intact D1 receptor function. Psychopharmacology. vol 118. issue 4. 1995-10-23. PMID:7568630. |
the higher doses of sch 23390 (5.0 and 10.0 micrograms/kg) eliminated the bromocriptine effect and the conditioned reward effect itself, respectively. |
1995-10-23 |
2023-08-12 |
rat |
| R Ranaldi, R J Beninge. Dopamine D1 and D2 antagonists attenuate amphetamine-produced enhancement of responding for conditioned reward in rats. Psychopharmacology. vol 113. issue 1. 1995-03-20. PMID:7862816. |
this was done by examining the effects of the d1 antagonist sch 23390 and the d2 antagonists pimozide and metoclopramide on amphetamine-produced enhancement of responding for conditioned reward. |
1995-03-20 |
2023-08-12 |
rat |
| R Ranaldi, R J Beninge. Dopamine D1 and D2 antagonists attenuate amphetamine-produced enhancement of responding for conditioned reward in rats. Psychopharmacology. vol 113. issue 1. 1995-03-20. PMID:7862816. |
sch 23390 (5.0 and 10.0 micrograms/kg, sc, 2 h before test) and pimozide (0.1 and 0.2 mg/kg, ip, 4 h before test) dose-dependently shifted the peak in the amphetamine dose-response function to the right, indicating an attenuation of conditioned reward. |
1995-03-20 |
2023-08-12 |
rat |
| C E Tedford, V L Coffin, V Ruperto, M Cohen, R D McQuade, R Johnson, H K Kim, C C Li. Determination of plasma and brain concentrations of SCH 39166 and their correlation to conditioned avoidance behavior in rats. Psychopharmacology. vol 113. issue 2. 1995-03-16. PMID:7855181. |
determination of plasma and brain concentrations of sch 39166 and their correlation to conditioned avoidance behavior in rats. |
1995-03-16 |
2023-08-12 |
rat |
| C E Tedford, V L Coffin, V Ruperto, M Cohen, R D McQuade, R Johnson, H K Kim, C C Li. Determination of plasma and brain concentrations of SCH 39166 and their correlation to conditioned avoidance behavior in rats. Psychopharmacology. vol 113. issue 2. 1995-03-16. PMID:7855181. |
plasma and brain concentrations of the dopamine d1 receptor antagonist, sch 39166, were measured and compared to behavioral activity in the conditioned avoidance response paradigm (car). |
1995-03-16 |
2023-08-12 |
rat |
| G Wolterink, G Phillips, M Cador, I Donselaar-Wolterink, T W Robbins, B J Everit. Relative roles of ventral striatal D1 and D2 dopamine receptors in responding with conditioned reinforcement. Psychopharmacology. vol 110. issue 3. 1995-02-23. PMID:7831431. |
intra-accumbens infusion of either the d1 receptor antagonist, sch 23390, or the d2 receptor antagonist, raclopride, completely blocked the potentiative effects of intra-accumbens d-amphetamine on responding with conditioned reinforcement and reduced responding to control levels. |
1995-02-23 |
2023-08-12 |
human |
| A Barnett, R D McQuade, C Tedfor. Highlights of D1 dopamine receptor antagonist research. Neurochemistry international. vol 20 Suppl. 1995-01-30. PMID:1365409. |
it differs from sch 23390, the prototype d1 receptor antagonist, by having reduced affinity for serotonin receptors and a longer duration of action in primates, as measured in the squirrel monkey conditioned avoidance paradigm. |
1995-01-30 |
2023-08-11 |
rat |
| A Agmo, M Gomez, Y Irazaba. Enkephalinase inhibition facilitates sexual behavior in the male rat but does not produce conditioned place preference. Pharmacology, biochemistry, and behavior. vol 47. issue 4. 1994-08-08. PMID:8029244. |
the effects of two enkephalinase inhibitors, sch 34826 and phospho-leu-phe, on male rat sexual behavior and conditioned place preference were evaluated. |
1994-08-08 |
2023-08-12 |
rat |
| A Agmo, M Gomez, Y Irazaba. Enkephalinase inhibition facilitates sexual behavior in the male rat but does not produce conditioned place preference. Pharmacology, biochemistry, and behavior. vol 47. issue 4. 1994-08-08. PMID:8029244. |
sch 34826, 100 and 30 mg/kg, and phospho-leu-phe, 25 micrograms, had no effect in the conditioned place preference procedure. |
1994-08-08 |
2023-08-12 |
rat |
| A C McCreary, C A Marsde. Cocaine-induced behaviour: dopamine D1 receptor antagonism by SCH 23390 prevents expression of conditioned sensitisation following repeated administration of cocaine. Neuropharmacology. vol 32. issue 4. 1993-06-21. PMID:8497339. |
cocaine-induced behaviour: dopamine d1 receptor antagonism by sch 23390 prevents expression of conditioned sensitisation following repeated administration of cocaine. |
1993-06-21 |
2023-08-12 |
Not clear |
| M L Wadenber. Antagonism by 8-OH-DPAT, but not ritanserin, of catalepsy induced by SCH 23390 in the rat. Journal of neural transmission. General section. vol 89. issue 1-2. 1992-12-04. PMID:1418867. |
in contrast to the finding in our previous report that raclopride and 8-oh-dpat in a synergistic manner produce a suppression of conditioned avoidance behavior, no such interaction was found between 8-oh-dpat (0.1 mg kg-1 sc) and sch 23390 (6 micrograms kg-1 sc) in the present study. |
1992-12-04 |
2023-08-11 |
rat |
| R J Care. Pavlovian conditioning of L-dopa induced movement. Psychopharmacology. vol 107. issue 2-3. 1992-07-30. PMID:1615121. |
additionally, drug tests with the combined dopaminergic receptor antagonists, sch 23390 (0.1 mg/kg) and haloperidol (0.5 mg/kg), at doses sufficient to block spontaneous behavior and l-dopa (20 mg/kg)-induced rotation, revealed that the conditioned contralateral rotation response, unlike l-dopa-induced contralateral rotation, is not affected by d1/d2 receptor blockade. |
1992-07-30 |
2023-08-11 |
rat |
| E J Mazurski, R J Beninge. Effects of selective drugs for dopaminergic D1 and D2 receptors on conditioned locomotion in rats. Psychopharmacology. vol 105. issue 1. 1992-01-13. PMID:1684056. |
test revealed conditioned hyperactivity with each agonist and metoclopramide whereas conditioned hypoactivity was seen with sch 23390. |
1992-01-13 |
2023-08-11 |
rat |
| R D McQuade, R A Duffy, V L Coffin, R E Chipkin, A Barnet. In vivo binding of SCH 39166: a D-1 selective antagonist. The Journal of pharmacology and experimental therapeutics. vol 257. issue 1. 1991-05-24. PMID:1826927. |
these studies demonstrated that sch 39166 binds to the d-1 receptor in vitro and inhibits the rat conditioned avoidance response, a test predictive of antipsychotic activity. |
1991-05-24 |
2023-08-11 |
rat |
| T S Shippenberg, A Her. Motivational effects of opioids: influence of D-1 versus D-2 receptor antagonists. European journal of pharmacology. vol 151. issue 2. 1988-11-23. PMID:2844553. |
acute administration of the d-1 antagonist, sch 23390 (0.001-0.5 mg/kg), produced conditioned place aversions. |
1988-11-23 |
2023-08-11 |
Not clear |
| R D McQuade, R Chipkin, N Amlaiky, M Caron, L Iorio, A Barnet. Characterization of the radioiodinated analogue of SCH 23390: in vitro and in vivo D-1 dopamine receptor binding studies. Life sciences. vol 43. issue 14. 1988-11-16. PMID:3050344. |
behavioral studies demonstrated that sch 38840 (med = 1.0 mg/kg, s.c.) blocked conditioned avoidance responding in rats, a measurement considered predictive of anti-psychotic activity in man. |
1988-11-16 |
2023-08-11 |
rat |
| T S Shippenberg, A Her. Place preference conditioning reveals the involvement of D1-dopamine receptors in the motivational properties of mu- and kappa-opioid agonists. Brain research. vol 436. issue 1. 1988-02-16. PMID:2961413. |
administration of the d1 receptor antagonist sch 23390 (0.001-0.5 mg/kg) or the kappa-opioid receptor agonist u-69593 (0.16 mg/kg) produced conditioned place aversions. |
1988-02-16 |
2023-08-11 |
Not clear |
| L C Iorio, A Barnett, F H Leitz, V P Houser, C A Kordub. SCH 23390, a potential benzazepine antipsychotic with unique interactions on dopaminergic systems. The Journal of pharmacology and experimental therapeutics. vol 226. issue 2. 1983-09-20. PMID:6135795. |
sch 23390 [r-(+)-8-chloro-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1h-3-benzazepine-7-ol) possesses pharmacologic effects similar to standard antipsychotics, including selective supression of conditioned avoidance responding in rats and squirrel monkeys, blockade of apomorphine-induced stereotypy in rats and blockade of methamphetamine-induced lethality in aggregated mice. |
1983-09-20 |
2023-08-12 |
mouse |