| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tahmineh Mokhtari, Elnaz Irandoost, Fatemeh Sheikhbahae. Stress, pain, anxiety, and depression in endometriosis-Targeting glial activation and inflammation. International immunopharmacology. vol 132. 2024-04-02. PMID:38565045. |
this review aims to discuss the relationship between systemic and local inflammatory responses in the central nervous system (cns), focusing on glial dysfunctions (astrocytes and microglia) as in critical brain regions involved in emotion, cognition, pain processing, anxiety, and depression. |
2024-04-02 |
2024-04-05 |
Not clear |
| Meishan Lu, Jiachen Shi, Xue Li, Yanjun Liu, Yuanfa Li. Long-term intake of thermo-induced oxidized oil results in anxiety-like and depression-like behaviors: involvement of microglia and astrocytes. Food & function. 2024-03-27. PMID:38533894. |
tioo primarily induced these two emotional disorders by affecting the differentiation of microglia, the level of inflammatory factors, the activation of astrocytes, and glutamate circulation in brain tissue. |
2024-03-27 |
2024-03-29 |
mouse |
| Daniela Laricchiuta, Martina Papi, Davide Decandia, Anna Panuccio, Debora Cutuli, Maurizio Peciccia, Claudia Mazzeschi, Laura Petrosin. The role of glial cells in mental illness: a systematic review on astroglia and microglia as potential players in schizophrenia and its cognitive and emotional aspects. Frontiers in cellular neuroscience. vol 18. 2024-02-29. PMID:38419655. |
the role of glial cells in mental illness: a systematic review on astroglia and microglia as potential players in schizophrenia and its cognitive and emotional aspects. |
2024-02-29 |
2024-03-02 |
Not clear |
| Daniela Laricchiuta, Martina Papi, Davide Decandia, Anna Panuccio, Debora Cutuli, Maurizio Peciccia, Claudia Mazzeschi, Laura Petrosin. The role of glial cells in mental illness: a systematic review on astroglia and microglia as potential players in schizophrenia and its cognitive and emotional aspects. Frontiers in cellular neuroscience. vol 18. 2024-02-29. PMID:38419655. |
the aim of this systematic review is to summarize the glial hallmarks of schizophrenia, choosing as cellular candidate the astroglia and microglia, and focusing also on disease-associated psychological (cognitive and emotional) changes. |
2024-02-29 |
2024-03-02 |
Not clear |
| Hongrui Zhu, Ao Guan, Jiayuan Liu, Li Peng, Zhi Zhang, Sheng Wan. Noteworthy perspectives on microglia in neuropsychiatric disorders. Journal of neuroinflammation. vol 20. issue 1. 2023-10-04. PMID:37794488. |
microglia are so versatile that they not only provide immune surveillance for central nervous system, but participate in neural circuitry development, brain blood vessels formation, blood-brain barrier architecture, and intriguingly, the regulation of emotions and behaviors. |
2023-10-04 |
2023-10-07 |
human |
| Pamela M Maras, Elaine K Hebda-Bauer, Megan H Hagenauer, Kathryn L Hilde, Peter Blandino, Stanley J Watson, Huda Aki. Differences in microglia morphological profiles reflect divergent emotional temperaments: insights from a selective breeding model. Translational psychiatry. vol 12. issue 1. 2022-03-16. PMID:35292624. |
differences in microglia morphological profiles reflect divergent emotional temperaments: insights from a selective breeding model. |
2022-03-16 |
2023-08-13 |
rat |
| Pamela M Maras, Elaine K Hebda-Bauer, Megan H Hagenauer, Kathryn L Hilde, Peter Blandino, Stanley J Watson, Huda Aki. Differences in microglia morphological profiles reflect divergent emotional temperaments: insights from a selective breeding model. Translational psychiatry. vol 12. issue 1. 2022-03-16. PMID:35292624. |
taken together, our results provide novel evidence linking variation in inborn temperament with differences in the baseline status of microglia and implicate a role for microglia in shaping enduring emotional characteristics. |
2022-03-16 |
2023-08-13 |
rat |
| Michaela R Breach, Courtney N Dye, Aarohi Joshi, Steven Platko, Rachel A Gilfarb, Annemarie R Krug, Dominic V Franceschelli, Anabel Galan, Claire M Dodson, Kathryn M Len. Maternal allergic inflammation in rats impacts the offspring perinatal neuroimmune milieu and the development of social play, locomotor behavior, and cognitive flexibility. Brain, behavior, and immunity. vol 95. 2021-06-23. PMID:33798637. |
here, we employed an allergen-induced model of maternal inflammation in rats to characterize levels of mast cells and microglia in the perinatal period in male and female offspring, as well as social, emotional, and cognitive behaviors throughout the lifespan. |
2021-06-23 |
2023-08-13 |
rat |
| Xiaoyun Guo, Ruizhi Mao, Lvchun Cui, Fan Wang, Rubai Zhou, Yun Wang, Jia Huang, Yuncheng Zhu, Yamin Yao, Guoqing Zhao, Zezhi Li, Jun Chen, Jinhui Wang, Yiru Fan. PAID study design on the role of PKC activation in immune/inflammation-related depression: a randomised placebo-controlled trial protocol. General psychiatry. vol 34. issue 2. 2021-04-30. PMID:33912799. |
we assume that the abnormality in pkc might result in abnormal microglia activation, neuronal apoptosis, significant changes in emotional and cognitive neural circuits, and trd. |
2021-04-30 |
2023-08-13 |
Not clear |
| Sung Ja Rhie, Eun-Yee Jung, Insop Shi. The role of neuroinflammation on pathogenesis of affective disorders. Journal of exercise rehabilitation. vol 16. issue 1. 2020-09-28. PMID:32161729. |
neuronflammation involves a combination of psychological, neuroendocrine, and nervous systems resulting in changes of neurotransmitter metabolism, dysregulation of the hypothalamuspituitary-adrenal axis, pathologic microglial cell activation, impaired neuroplasticity, and structural and functional brain changes affecting cognition and emotional behavior. |
2020-09-28 |
2023-08-13 |
Not clear |
| Xuerui Wang, Xiaolong Xu, Yuhong Guo, Po Huang, Yanxiang Ha, Rui Zhang, Yunjing Bai, Xuran Cui, Shasha He, Qingquan Li. Qiang Xin 1 Formula Suppresses Excessive Pro-Inflammatory Cytokine Responses and Microglia Activation to Prevent Cognitive Impairment and Emotional Dysfunctions in Experimental Sepsis. Frontiers in pharmacology. vol 11. 2020-09-28. PMID:32457609. |
qiang xin 1 formula suppresses excessive pro-inflammatory cytokine responses and microglia activation to prevent cognitive impairment and emotional dysfunctions in experimental sepsis. |
2020-09-28 |
2023-08-13 |
mouse |
| Yasuhisa Ano, Masahiro Kita, Shiho Kitaoka, Tomoyuki Furuyashik. Leucine-Histidine Dipeptide Attenuates Microglial Activation and Emotional Disturbances Induced by Brain Inflammation and Repeated Social Defeat Stress. Nutrients. vol 11. issue 9. 2020-03-03. PMID:31505850. |
these results indicate that lh dipeptide suppressed the activation of microglia and ameliorated depression-associated emotional disturbances. |
2020-03-03 |
2023-08-13 |
mouse |
| Kazuhide Inoue, Makoto Tsud. Microglia in neuropathic pain: cellular and molecular mechanisms and therapeutic potential. Nature reviews. Neuroscience. vol 19. issue 3. 2019-08-27. PMID:29416128. |
it is also becoming clear that microglia have active roles in brain regions important for the emotional and memory-related aspects of chronic pain. |
2019-08-27 |
2023-08-13 |
human |
| Makoto Tsud. Microglia in the CNS and Neuropathic Pain. Advances in experimental medicine and biology. vol 1099. 2019-07-26. PMID:30306516. |
recent studies have also revealed active roles for microglia in brain regions important for emotion and memory. |
2019-07-26 |
2023-08-13 |
Not clear |
| Andrew E Arrant, Anthony J Filiano, Daniel E Unger, Allen H Young, Erik D Roberso. Restoring neuronal progranulin reverses deficits in a mouse model of frontotemporal dementia. Brain : a journal of neurology. vol 140. issue 5. 2017-10-30. PMID:28379303. |
loss-of-function mutations in progranulin (grn), a secreted glycoprotein expressed by neurons and microglia, are a common autosomal dominant cause of frontotemporal dementia, a neurodegenerative disease commonly characterized by disrupted social and emotional behaviour. |
2017-10-30 |
2023-08-13 |
mouse |
| b' Jean-Christophe Delpech, Charlotte Madore, Agnes Nadjar, Corinne Joffre, Eric S Wohleb, Sophie Lay\\xc3\\xa. Microglia in neuronal plasticity: Influence of stress. Neuropharmacology. vol 96. issue Pt A. 2016-03-16. PMID:25582288.' |
interestingly, psychological stress can perturb the function of microglia in association with an impaired neuronal plasticity and the development of emotional behavior alterations. |
2016-03-16 |
2023-08-13 |
Not clear |
| Xudong Feng, Yu-Lung Lin, Li-Na We. Behavioral stress reduces RIP140 expression in astrocyte and increases brain lipid accumulation. Brain, behavior, and immunity. vol 46. 2016-02-04. PMID:25697398. |
receptor-interacting protein 140 (rip140) is highly expressed in the brain, and acts in neurons and microglia to affect emotional responses. |
2016-02-04 |
2023-08-13 |
Not clear |
| Tomoyuki Furuyashik. Roles of dopamine and inflammation-related molecules in behavioral alterations caused by repeated stress. Journal of pharmacological sciences. vol 120. issue 2. 2013-03-12. PMID:22986366. |
several findings suggest that microglia activated by repeated stress are involved in emotional and cognitive changes as a source of inflammation-related molecules such as pge(2) and il-1β. |
2013-03-12 |
2023-08-12 |
Not clear |
| T Panigada, R-D Gosseli. Behavioural alteration in chronic pain: are brain glia involved? Medical hypotheses. vol 77. issue 4. 2011-12-29. PMID:21741179. |
the theory developed in the present article posits that alterations in glial cells (astrocytes and microglia) in cortical and limbic brain regions might be the origin of such emotional and cognitive chronic pain-associated impairments. |
2011-12-29 |
2023-08-12 |
Not clear |