| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mengshi Dong, Likun Xia, Min Lu, Chao Li, Ke Xu, Lina Zhan. A failed top-down control from the prefrontal cortex to the amygdala in generalized anxiety disorder: Evidence from resting-state fMRI with Granger causality analysis. Neuroscience letters. vol 707. 2020-03-11. PMID:31163226. |
in generalized anxiety disorder (gad), abnormal top-down control from the prefrontal cortex (pfc) to the amygdala is a widely accepted hypothesis through which an "emotional dysregulation model" may be explained. |
2020-03-11 |
2023-08-13 |
Not clear |
| Mengshi Dong, Likun Xia, Min Lu, Chao Li, Ke Xu, Lina Zhan. A failed top-down control from the prefrontal cortex to the amygdala in generalized anxiety disorder: Evidence from resting-state fMRI with Granger causality analysis. Neuroscience letters. vol 707. 2020-03-11. PMID:31163226. |
however, whether and how the pfc directly exerts abnormal top-down control on the amygdala remains largely unknown. |
2020-03-11 |
2023-08-13 |
Not clear |
| Mengshi Dong, Likun Xia, Min Lu, Chao Li, Ke Xu, Lina Zhan. A failed top-down control from the prefrontal cortex to the amygdala in generalized anxiety disorder: Evidence from resting-state fMRI with Granger causality analysis. Neuroscience letters. vol 707. 2020-03-11. PMID:31163226. |
our findings support and advance the "insufficient top-down control" hypothesis by identifying a failed top-down control from the prefrontal cortex to the amygdala in gad. |
2020-03-11 |
2023-08-13 |
Not clear |
| Evangelia G Chrysikou, Erik K Wing, Wessel O van Da. Transcranial Direct Current Stimulation Over the Prefrontal Cortex in Depression Modulates Cortical Excitability in Emotion Regulation Regions as Measured by Concurrent Functional Magnetic Resonance Imaging: An Exploratory Study. Biological psychiatry. Cognitive neuroscience and neuroimaging. 2020-02-29. PMID:32111579. |
a well-established impaired top-down network for effortful emotion regulation (er) in major depressive disorder (mdd) includes the dorsal and ventromedial prefrontal cortex (pfc) and the amygdala. |
2020-02-29 |
2023-08-13 |
Not clear |
| Pegah Sarkheil, Martin Klasen, Frank Schneider, Rainer Goebel, Klaus Mathia. Amygdala response and functional connectivity during cognitive emotion regulation of aversive image sequences. European archives of psychiatry and clinical neuroscience. vol 269. issue 7. 2020-02-10. PMID:30008118. |
the inverse relationship between pfc and amygdala was compromised during elongated blocks of reappraisal, reflecting a reduction in engagement of the top-down prefrontal regulatory circuitry upon repeated exposure to negative stimuli. |
2020-02-10 |
2023-08-13 |
human |
| Yury Koush, Swann Pichon, Simon B Eickhoff, Dimitri Van De Ville, Patrik Vuilleumier, Frank Scharnowsk. Brain networks for engaging oneself in positive-social emotion regulation. NeuroImage. vol 189. 2020-01-23. PMID:30594682. |
increased top-down connectivity from the superior frontal gyrus (sfg) controls affective valuation in the ventromedial and dorsomedial pfc, self-referential processes in the tpj, and modulate emotional responses in the amygdala via the ventromedial pfc. |
2020-01-23 |
2023-08-13 |
Not clear |
| Zhaowen Liu, Jie Zhang, Kai Zhang, Junying Zhang, Xiaojing Li, Wei Cheng, Mingli Li, Liansheng Zhao, Wei Deng, Wanjun Guo, Xiaohong Ma, Qiang Wang, Paul M Matthews, Jianfeng Feng, Tao L. Distinguishable brain networks relate disease susceptibility to symptom expression in schizophrenia. Human brain mapping. vol 39. issue 9. 2019-12-17. PMID:29691943. |
we hypothesize that top-down control from heteromodal prefrontal cortex to posterior transmodal cortex contributes to positive symptoms of schizophrenia. |
2019-12-17 |
2023-08-13 |
Not clear |
| Jahrane Dale, Haocheng Zhou, Qiaosheng Zhang, Erik Martinez, Sile Hu, Kevin Liu, Louise Urien, Zhe Chen, Jing Wan. Scaling Up Cortical Control Inhibits Pain. Cell reports. vol 23. issue 5. 2019-10-01. PMID:29719246. |
the prefrontal cortex (pfc) is known to exert top-down regulation of sensory inputs; unfortunately, how individual pfc neurons respond to an acute pain signal is not well characterized. |
2019-10-01 |
2023-08-13 |
rat |
| Margaret A Broadwater, Sung-Ho Lee, Yang Yu, Hongtu Zhu, Fulton T Crews, Donita L Robinson, Yen-Yu Ian Shi. Adolescent alcohol exposure decreases frontostriatal resting-state functional connectivity in adulthood. Addiction biology. vol 23. issue 2. 2019-09-17. PMID:28691248. |
connectivity of the prefrontal cortex (pfc) matures through adolescence, coinciding with emergence of adult executive function and top-down inhibitory control over behavior. |
2019-09-17 |
2023-08-13 |
rat |
| Wei Hung Chang, I Hui Lee, Mei Hung Chi, Shih-Hsien Lin, Kao Chin Chen, Po See Chen, Nan Tsing Chiu, Wei Jen Yao, Yen Kuang Yan. Prefrontal cortex modulates the correlations between brain-derived neurotrophic factor level, serotonin, and the autonomic nervous system. Scientific reports. vol 8. issue 1. 2019-08-16. PMID:29416077. |
top-down regulation in the human brain and anatomical connections between the prefrontal cortex (pfc) and specific catecholamine-related regions have been well-studied. |
2019-08-16 |
2023-08-13 |
human |
| Hamid Karimi-Rouzbahani, Nasour Bagheri, Reza Ebrahimpou. Invariant object recognition is a personalized selection of invariant features in humans, not simply explained by hierarchical feed-forward vision models. Scientific reports. vol 7. issue 1. 2019-08-12. PMID:29089520. |
this implies that, even in rapid object recognition, rather than a set of feed-forward mechanisms which extract diagnostic features from objects in a hard-wired fashion, the bottom-up visual pathways receive, through top-down connections, task-related information possibly processed in prefrontal cortex. |
2019-08-12 |
2023-08-13 |
human |
| Haocheng Zhou, Qiaosheng Zhang, Erik Martinez, Jahrane Dale, Eric Robinson, Dong Huang, Jing Wan. A novel neuromodulation strategy to enhance the prefrontal control to treat pain. Molecular pain. vol 15. 2019-08-12. PMID:31012383. |
the prefrontal cortex is known to provide top-down control of pain, and hence neuromodulation methods that selectively enhance the activities in this brain region during pain episodes have the potential to provide analgesia. |
2019-08-12 |
2023-08-13 |
rat |
| Andreas Wutz, Roman Loonis, Jefferson E Roy, Jacob A Donoghue, Earl K Mille. Different Levels of Category Abstraction by Different Dynamics in Different Prefrontal Areas. Neuron. vol 97. issue 3. 2019-07-22. PMID:29395915. |
bottom-up dynamics (stimulus-locked gamma power and spiking) in the ventral pfc processed more low-level abstractions, whereas top-down dynamics (beta power and beta spike-lfp coherence) in the dorsal pfc processed more high-level abstractions. |
2019-07-22 |
2023-08-13 |
monkey |
| Yu-Chin Chiu, Tobias Egne. Cortical and subcortical contributions to context-control learning. Neuroscience and biobehavioral reviews. vol 99. 2019-07-11. PMID:30685484. |
traditionally, research has focused on delineating the sources of top-down biasing, implicating the lateral prefrontal cortex. |
2019-07-11 |
2023-08-13 |
Not clear |
| Dennis Sasikumar, Erik Emeric, Veit Stuphorn, Charles E Conno. First-Pass Processing of Value Cues in the Ventral Visual Pathway. Current biology : CB. vol 28. issue 4. 2019-06-14. PMID:29429619. |
here, we used microelectrode recording in behaving monkeys to test two possible mechanisms for category-specific value-cue processing: (1) previous findings suggest that prefrontal cortex (pfc) identifies object categories, and based on category identity, pfc could use top-down attentional modulation to enhance visual processing of category-specific value cues, providing signals to pfc for calculating value, and (2) a faster mechanism would be first-pass visual processing of category-specific value cues, immediately providing the necessary visual information to pfc. |
2019-06-14 |
2023-08-13 |
monkey |
| Roger Marek, Yajie Sun, Pankaj Sa. Neural circuits for a top-down control of fear and extinction. Psychopharmacology. vol 236. issue 1. 2019-04-08. PMID:30215217. |
here, we highlight recent advances in our understanding of how the prefrontal cortex may mediate such a top-down regulation. |
2019-04-08 |
2023-08-13 |
Not clear |
| Qiaomu Miao, Gaoyan Zhang, Weiran Yan, Baolin Li. Investigating the Brain Neural Mechanism when Signature Objects were Masked during a Scene Categorization Task using Functional MRI. Neuroscience. vol 388. 2019-03-29. PMID:30056114. |
changes in top-down modulation effect were revealed in the fc from the dorsolateral prefrontal cortex (dlpfc) to loc and the extrastriate visual cortex, possibly participating in conscious object recognition. |
2019-03-29 |
2023-08-13 |
human |
| Miroslaw Wyczesany, Paolo Capotosto, Filippo Zappasodi, Giulia Pret. Hemispheric asymmetries and emotions: Evidence from effective connectivity. Neuropsychologia. vol 121. 2019-02-11. PMID:30352221. |
finally, the results suggest a crucial role of the right dorsolateral prefrontal cortex in a top-down regulation toward different areas involved in emotional processing. |
2019-02-11 |
2023-08-13 |
Not clear |
| Lars Meyer, Anne Elsner, Sabrina Turker, Philipp Kuhnke, Gesa Hartwigse. Perturbation of left posterior prefrontal cortex modulates top-down processing in sentence comprehension. NeuroImage. vol 181. 2019-02-04. PMID:30055371. |
perturbation of left posterior prefrontal cortex modulates top-down processing in sentence comprehension. |
2019-02-04 |
2023-08-13 |
human |
| Vadim Zotev, Raquel Phillips, Masaya Misaki, Chung Ki Wong, Brent E Wurfel, Frank Krueger, Matthew Feldner, Jerzy Bodurk. Real-time fMRI neurofeedback training of the amygdala activity with simultaneous EEG in veterans with combat-related PTSD. NeuroImage. Clinical. vol 19. 2019-01-30. PMID:30035008. |
posttraumatic stress disorder (ptsd) is a chronic and disabling neuropsychiatric disorder characterized by insufficient top-down modulation of the amygdala activity by the prefrontal cortex. |
2019-01-30 |
2023-08-13 |
Not clear |