All Relations between working memory and mesencephalon

Publication Sentence Publish Date Extraction Date Species
Margaret P Schmill, Zoe Thompson, Daisy Lee, Laurence Haddadin, Shaarang Mitra, Raymond Ezzat, Samantha Shelton, Phillip Levin, Sogol Behnam, Kelly J Huffman, Theodore Garlan. Hippocampal, whole midbrain, red nucleus, and ventral tegmental area volumes are increased by selective breeding for high voluntary wheel-running behavior. Brain, behavior and evolution. 2023-08-21. PMID:37604130. in hr compared to c mice, adjusting for body mass, both the red nucleus (rn) of the midbrain and the hippocampus (hpc) were significantly larger, and the whole midbrain (wm) tended to be larger, with no effect of wheel access nor any interactions. 2023-08-21 2023-09-07 mouse
Gal Nir-Cohen, Tobias Egner, Yoav Kessle. The Neural Correlates of Updating and Gating in Procedural Working Memory. Journal of cognitive neuroscience. 2023-03-28. PMID:36976906. in neural terms, opening the gate to procedural wm was associated with activity in medial pfc, posterior parietal cortex (ppc), the basal ganglia (bg), thalamus, and midbrain, but only when the task set needed to be updated. 2023-03-28 2023-08-14 human
Matthew A Weber, Gemma de Choisy, Ramasamy Thangavel, Mackenzie M Conlon, Hisham A Abdelmotilib, Oday Halhouli, Qiang Zhang, Joel C Geerling, Nandakumar S Narayanan, Georgina M Aldridg. Alpha-synuclein pre-formed fibrils injected into prefrontal cortex primarily impact cortical and subcortical structures and lead to restricted behavioral impacts. bioRxiv : the preprint server for biology. 2023-02-13. PMID:36778400. we report that pfc pffs: 1) induced α-syn deposition in multiple cortical and subcortical regions with sparse aggregation in midbrain and brainstem nuclei; 2) did not affect interval timing or working memory but did mildly alter behavioral flexibility as measured by reversal learning; 3) increased open field exploration; and 4) did not affect susceptibility to model of cortical-dominant pathology adds to our understanding of the etiology of varied symptoms in pdd and lbd. 2023-02-13 2023-08-14 mouse
Janna Krahe, Imis Dogan, Claire Didszun, Shahram Mirzazade, Alexa Haeger, Nadim Joni Shah, Ilaria A Giordano, Thomas Klockgether, Guillaume Madelin, Jörg B Schulz, Sandro Romanzetti, Kathrin Reet. Increased brain tissue sodium concentration in Friedreich ataxia: A multimodal MR imaging study. NeuroImage. Clinical. vol 34. 2022-05-02. PMID:35500368. compared to controls, patients showed reduced brain volume in the right cerebellar lobules i-v (difference in means: -0.039% of total intracranial volume [ticv]; cohen's d = 0.83), cerebellar white matter (wm) (-0.105%ticv; d = 1.16), and brainstem (-0.167%ticv; d = 1.22), including pons (-0.102%ticv; d = 1.00), medulla (-0.036%ticv; d = 1.72), and midbrain (-0.028%ticv; d = 1.05). 2022-05-02 2023-08-13 Not clear
James N Baraniu. Review of the Midbrain Ascending Arousal Network Nuclei and Implications for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), Gulf War Illness (GWI) and Postexertional Malaise (PEM). Brain sciences. vol 12. issue 2. 2022-02-25. PMID:35203896. in a two-day model of pem, submaximal exercise induced significant changes in activation of the dorsal midbrain during a high cognitive load working memory task (washington 2020) (baraniuk this issue). 2022-02-25 2023-08-13 Not clear
Stefania Sarno, Manuel Beirán, Joan Falcó-Roget, Gabriel Diaz-deLeon, Román Rossi-Pool, Ranulfo Romo, Néstor Parg. Dopamine firing plays a dual role in coding reward prediction errors and signaling motivation in a working memory task. Proceedings of the National Academy of Sciences of the United States of America. vol 119. issue 2. 2022-01-07. PMID:34992139. here, we investigated midbrain da activity in monkeys performing a discrimination task in which the animal had to use working memory (wm) to report which of two sequentially applied vibrotactile stimuli had the higher frequency. 2022-01-07 2023-08-13 monkey
Uttam Kumar, Anshita Singh, Prakash Paddakany. Extensive long-term verbal memory training is associated with brain plasticity. Scientific reports. vol 11. issue 1. 2021-10-28. PMID:33958676. the results revealed an increased grey matter (gm) and white matter (wm) in the midbrain, pons, thalamus, parahippocampus, and orbitofrontal regions in pandits. 2021-10-28 2023-08-13 human
Mary L Schneider, Colleen F Moore, Elizabeth O Ahlers, Todd E Barnhart, Bradley T Christian, Onofre T DeJesus, Jonathan W Engle, James E Holden, Julie A Larson, Jeffrey M Moirano, Dhanabalan Murali, Robert J Nickles, Leslie M Resch, Alexander K Convers. PET Measures of D1, D2, and DAT Binding Are Associated With Heightened Tactile Responsivity in Rhesus Macaques: Implications for Sensory Processing Disorder. Frontiers in integrative neuroscience. vol 13. 2020-10-01. PMID:31379528. clinical research indicates that children with spd show greater prevalence of difficulties in complex cognitive behavior including working memory, behavioral flexibility, and regulation of sensory and affective functions, which are related to prefrontal cortex (pfc), striatal, and midbrain regions. 2020-10-01 2023-08-13 human
Wen Jia Chai, Aini Ismafairus Abd Hamid, Jafri Malin Abdulla. Working Memory From the Psychological and Neurosciences Perspectives: A Review. Frontiers in psychology. vol 9. 2020-09-29. PMID:29636715. recent studies have subsequently implicated the roles of subcortical regions (such as the midbrain and cerebellum) in working memory. 2020-09-29 2023-08-13 Not clear
Mario Mascalchi, Emilia Salvadori, Nicola Toschi, Marco Giannelli, Stefano Orsolini, Stefano Ciulli, Andrea Ginestroni, Anna Poggesi, Antonio Giorgio, Francesca Lorenzini, Marco Pasi, Nicola De Stefano, Leonardo Pantoni, Domenico Inzitari, Stefano Diciott. DTI-derived indexes of brain WM correlate with cognitive performance in vascular MCI and small-vessel disease. A TBSS study. Brain imaging and behavior. vol 13. issue 3. 2019-11-12. PMID:29744799. the moca score significantly correlated with fractional anisotropy (positive correlation) and mean, axial and radial diffusivity (negative correlations) in wm tracts of cerebral hemispheres and corpus callosum, as well as in the intra-thalamic wm tracts and the superior cerebellar peduncle decussation in the midbrain. 2019-11-12 2023-08-13 human
C A Paladini, J Roepe. Generating bursts (and pauses) in the dopamine midbrain neurons. Neuroscience. vol 282. 2018-01-26. PMID:25073045. dopamine (da) midbrain neurons project to several striatal and cortical target areas and are essentially involved in a puzzling variety of important brain functions such as action selection and motor performance, motivation and reward-based learning, but also working memory and cognition. 2018-01-26 2023-08-13 Not clear
Theodore P Criswell, Matthew MacGregor Sharp, Howard Dobson, Ciara Finucane, Roy O Weller, Ajay Verma, Roxana O Carar. The structure of the perivascular compartment in the old canine brain: a case study. Clinical science (London, England : 1979). vol 131. issue 22. 2017-11-27. PMID:28982724. dilatation of periarteriolar spaces in mri of the ageing human brains occurs in white matter (wm), basal ganglia and midbrain but not in cerebral cortex. 2017-11-27 2023-08-13 human
Kanwar Virdee, Jiska Kentrop, Bianca Jupp, Bethany Venus, Daniel Hensman, Simon McArthur, James Wilkinson, Trevor W Robbins, Glenda Gillies, Jeffrey W Dalle. Counteractive effects of antenatal glucocorticoid treatment on D1 receptor modulation of spatial working memory. Psychopharmacology. vol 233. issue 21-22. 2017-11-16. PMID:27553822. however, the consequences of this expansion in midbrain dopamine (da) neurons for behavioural processes in adulthood are poorly understood, including working memory that depends on da transmission in the prefrontal cortex (pfc). 2017-11-16 2023-08-13 rat
D J Greene, A C Williams Iii, J M Koller, B L Schlaggar, K J Blac. Brain structure in pediatric Tourette syndrome. Molecular psychiatry. vol 22. issue 7. 2017-11-02. PMID:27777415. the ts group demonstrated lower wm volume bilaterally in orbital and medial prefrontal cortex, and greater gm volume in posterior thalamus, hypothalamus and midbrain. 2017-11-02 2023-08-13 Not clear
Chung-Man Moon, Byeong-Chae Kim, Gwang-Woo Jeon. Effects of donepezil on brain morphometric and metabolic changes in patients with Alzheimer's disease: A DARTEL-based VBM and (1)H-MRS. Magnetic resonance imaging. vol 34. issue 7. 2017-07-05. PMID:27131829. in the wm volumetric analysis, untreated and treated patients showed significant volume reductions in the posterior limb of internal capsule (plic), cerebral peduncle of the midbrain and phg compared to healthy controls. 2017-07-05 2023-08-13 human
Chung-Man Moon, Gwang-Woo Jeon. Abnormalities in gray and white matter volumes associated with explicit memory dysfunction in patients with generalized anxiety disorder. Acta radiologica (Stockholm, Sweden : 1987). vol 58. issue 3. 2017-02-13. PMID:27273376. results patients with gad showed significantly reduced gm volumes in the midbrain (mb), thalamus, hippocampus (hip), insula, and superior temporal gyrus (stg); and reduced wm volumes in the mb, anterior limb of the internal capsule (alic), dorsolateral prefrontal cortex (dlpfc), and precentral gyrus (prg). 2017-02-13 2023-08-13 human
Chung-Man Moon, Gwang-Woo Jeon. Brain morphological alterations and cellular metabolic changes in patients with generalized anxiety disorder: A combined DARTEL-based VBM and (1)H-MRS study. Magnetic resonance imaging. vol 34. issue 4. 2016-12-13. PMID:26708039. the patients showed significantly reduced white matter (wm) volumes in the midbrain (mb), precentral gyrus (prg), dorsolateral prefrontal cortex (dlpfc) and anterior limb of the internal capsule (alic) compared to the controls. 2016-12-13 2023-08-13 Not clear
David Drijkoningen, Inge Leunissen, Karen Caeyenberghs, Wouter Hoogkamer, Stefan Sunaert, Jacques Duysens, Stephan P Swinne. Regional volumes in brain stem and cerebellum are associated with postural impairments in young brain-injured patients. Human brain mapping. vol 36. issue 12. 2016-10-06. PMID:26441014. moreover, across all participants, worse postural control performance was associated with lower wm volume in the pons, medulla, midbrain, superior and middle cerebellar peduncles and cerebellum. 2016-10-06 2023-08-13 human
David Drijkoningen, Inge Leunissen, Karen Caeyenberghs, Wouter Hoogkamer, Stefan Sunaert, Jacques Duysens, Stephan P Swinne. Regional volumes in brain stem and cerebellum are associated with postural impairments in young brain-injured patients. Human brain mapping. vol 36. issue 12. 2016-10-06. PMID:26441014. volume loss in tbi patients was revealed in global cerebellar gm, global infratentorial wm, middle cerebellar peduncles, pons and midbrain. 2016-10-06 2023-08-13 human
Francesca Trojsi, Giuseppina Caiazzo, Daniele Corbo, Giovanni Piccirillo, Viviana Cristillo, Cinzia Femiano, Teresa Ferrantino, Mario Cirillo, Maria Rosaria Monsurrò, Fabrizio Esposito, Gioacchino Tedesch. Microstructural changes across different clinical milestones of disease in amyotrophic lateral sclerosis. PloS one. vol 10. issue 3. 2016-02-09. PMID:25793718. finally, als patients in stage 3 (with impairment of three functional regions) exhibited decreased fa and increased md and rd (p<0.05, corrected) within wm underneath bilateral pre and postcentral gyri, corpus callosum midbody, long associative tracts and midbrain, while no significant clusters of gm atrophy were observed. 2016-02-09 2023-08-13 Not clear