All Relations between 5-ht receptor 1a and Azapirones

Reference Sentence Publish Date Extraction Date Species
Magdalena Jastrz\\xc4\\x99bska-Wi\\xc4\\x99sek, Anna Weso\\xc5\\x82owska, Marcin Ko\\xc5\\x82aczkowski, Mark A Varney, Adrian Newman-Tancredi, RonanY Depoorter. The selective 5-HT1A receptor agonist, NLX-112, overcomes tetrabenazine-induced catalepsy and depression-like behavior in the rat. Behavioural pharmacology vol issue 2022 35695543 the prototypical 5-ht1a agonist, (\xc2\xb1)8-oh-dpat, and the 5-ht1a partial agonist/dopamine d2 receptor blocker, buspirone, were used as comparators. 2022-06-13 2022-06-14 Not clear
Anne R de Kort, Elbert A Joosten, Jacob Patijn, Dick Tibboel, Nynke J van den Hooge. Selective Targeting of Serotonin 5-HT1a and 5-HT3 Receptors Attenuates Acute and Long-Term Hypersensitivity Associated With Neonatal Procedural Pain. Frontiers in pain research (Lausanne, Switzerland) vol 3 issue 2022 35571143 the current study aims to attenuate acute and long-term hypersensitivity associated with neonatal procedural pain using ondansetron (a 5-ht3 antagonist) and buspirone (a 5-ht1a agonist) in a well-established rat model of repetitive needle pricking. 2022-05-16 2022-06-13 Not clear
Urmila Aswar, Hrudaya Shende, Manoj Aswa. Buspirone, a 5-HT1A agonist attenuates social isolation-induced behavior deficits in rats: a comparative study with fluoxetine. Behavioural pharmacology vol issue 2022 35438678 buspirone, a 5-ht1a agonist attenuates social isolation-induced behavior deficits in rats: a comparative study with fluoxetine. 2022-04-19 2022-04-25 Not clear
Cecilia L Bergeria, Hongjun Tan, Denis Antoine, Elise M Weerts, Andrew S Huhn, J Gregory Hobelmann, Kelly E Dun. A double-blind, randomized, placebo-controlled, pilot clinical trial examining buspirone as an adjunctive medication during buprenorphine-assisted supervised opioid withdrawal. Experimental and clinical psychopharmacology vol issue 2022 35266779 buspirone is a d2 antagonist and 5-ht1a agonist that may decrease opioid withdrawal. 2022-03-10 2022-04-14 Not clear
Sarah Thomas Broome, Alessandro Castorin. The Anxiolytic Drug Buspirone Prevents Rotenone-Induced Toxicity in a Mouse Model of Parkinson's Disease. International journal of molecular sciences vol 23 issue 3 2022 35163768 the anxiolytic drug buspirone, a serotonin receptor 1a agonist, also functions as a potent d3r antagonist. 2022-02-15 2022-02-17 Not clear
Darakhshan Jabeen Haleem, Tabinda Salman, Shazia Nawaz, Huma Ikra. Co-treatment with low doses of buspirone prevents rewarding effects of methylphenidate and upregulates expression of 5-HT1A receptor mRNA in the nucleus accumbens. Behavioural brain research vol 418 issue 2021 34752844 co-treatment with low doses of buspirone prevents rewarding effects of methylphenidate and upregulates expression of 5-ht1a receptor mrna in the nucleus accumbens. 2022-02-03 2022-01-13 Not clear
Darakhshan Jabeen Haleem, Tabinda Salman, Shazia Nawaz, Huma Ikra. Co-treatment with low doses of buspirone prevents rewarding effects of methylphenidate and upregulates expression of 5-HT1A receptor mRNA in the nucleus accumbens. Behavioural brain research vol 418 issue 2021 34752844 animals treated with mpd exhibit a downregulation of 5-ht1a receptor mrna in the nucleus accumbens which is also prevented in rats co-treated with 0.1 and 0.3\xc2\xa0mg/kg but not 1.0 and 2.0\xc2\xa0mg/kg buspirone. 2022-02-03 2022-01-13 Not clear
Darakhshan Jabeen Haleem, Tabinda Salman, Shazia Nawaz, Huma Ikra. Co-treatment with low doses of buspirone prevents rewarding effects of methylphenidate and upregulates expression of 5-HT1A receptor mRNA in the nucleus accumbens. Behavioural brain research vol 418 issue 2021 34752844 administration of buspirone in these doses is not rewarding in cpp test and upregulates 5-ht1a receptor mrna in the nucleus accumbens. 2022-02-03 2022-01-13 Not clear
Darakhshan Jabeen Haleem, Tabinda Salman, Shazia Nawaz, Huma Ikra. Co-treatment with low doses of buspirone prevents rewarding effects of methylphenidate and upregulates expression of 5-HT1A receptor mRNA in the nucleus accumbens. Behavioural brain research vol 418 issue 2021 34752844 co-treatment with low doses of buspirone prevents rewarding effects of methylphenidate and upregulates expression of 5-ht1a receptor mrna in the nucleus accumbens. 2021-12-11 2022-01-13 Not clear
Darakhshan Jabeen Haleem, Tabinda Salman, Shazia Nawaz, Huma Ikra. Co-treatment with low doses of buspirone prevents rewarding effects of methylphenidate and upregulates expression of 5-HT1A receptor mRNA in the nucleus accumbens. Behavioural brain research vol 418 issue 2021 34752844 animals treated with mpd exhibit a downregulation of 5-ht1a receptor mrna in the nucleus accumbens which is also prevented in rats co-treated with 0.1 and 0.3\xc2\xa0mg/kg but not 1.0 and 2.0\xc2\xa0mg/kg buspirone. 2021-12-11 2022-01-13 Not clear
Darakhshan Jabeen Haleem, Tabinda Salman, Shazia Nawaz, Huma Ikra. Co-treatment with low doses of buspirone prevents rewarding effects of methylphenidate and upregulates expression of 5-HT1A receptor mRNA in the nucleus accumbens. Behavioural brain research vol 418 issue 2021 34752844 administration of buspirone in these doses is not rewarding in cpp test and upregulates 5-ht1a receptor mrna in the nucleus accumbens. 2021-12-11 2022-01-13 Not clear
Jillian H Broadbear, Ronan Y Depoortere, Kristina Vacy, David Ralph, Brendan J Tunstall, Adrian Newman-Tancred. Discriminative stimulus properties of the 5-HT1A receptor biased agonists NLX-101 and F13714, in rats trained to discriminate 8-OH-DPAT from saline. Behavioural pharmacology vol 32 issue 8 2021 34751175 the 5-ht1a receptor partial agonist, buspirone, partially substituted (~80%) at 1 and 2 mg/kg i.p., doses which also decreased response rates. 2021-11-17 2022-01-13 Not clear
Jillian H Broadbear, Ronan Y Depoortere, Kristina Vacy, David Ralph, Brendan J Tunstall, Adrian Newman-Tancred. Discriminative stimulus properties of the 5-HT1A receptor biased agonists NLX-101 and F13714, in rats trained to discriminate 8-OH-DPAT from saline. Behavioural pharmacology vol 32 issue 8 2021 34751175 the selective 5-ht1a receptor antagonist way-100\xe2\x80\x89635 (1 mg/kg s.c., 40\xe2\x80\x89min pretreatment) elicited almost no responding on the 8-oh-dpat-associated lever by itself, but blocked the discriminative stimulus effects produced by administration (20\xe2\x80\x89min pretreatment) of 8-oh-dpat (0.1 mg/kg), f13714 (0.025 mg/kg), nlx-101 (0.5 mg/kg) or buspirone (1 mg/kg). 2021-11-17 2022-01-13 Not clear
Sarah Thomas Broome, Teagan Fisher, Alen Faiz, Kevin A Keay, Giuseppe Musumeci, Ghaith Al-Badri, Alessandro Castorin. Assessing the Anti-Inflammatory Activity of the Anxiolytic Drug Buspirone Using CRISPR-Cas9 Gene Editing in LPS-Stimulated BV-2 Microglial Cells. Cells vol 10 issue 6 2021 34070429 buspirone is an anxiolytic drug with robust serotonin receptor 1a (htr1a) agonist activities. 2021-11-01 2022-01-13 Not clear
Jeon-Kyung Kim, Sang-Kap Han, Min-Kyung Joo, Dong-Hyun Ki. Buspirone alleviates anxiety, depression, and colitis; and modulates gut microbiota in mice. Scientific reports vol 11 issue 1 2021 33731795 buspirone, an agonist for serotonin 5-ht1a receptors, is used for the treatment of anxiety/depression. 2021-10-13 2022-01-13 Not clear
Jeffrey T Dunn, Jessica Mroczek, Harsh R Patel, Michael E Ragozzin. Tandospirone, a Partial 5-HT1A Receptor Agonist, Administered Systemically or Into Anterior Cingulate Attenuates Repetitive Behaviors in Shank3B Mice. The international journal of neuropsychopharmacology vol 23 issue 8 2021 32619232 tandospirone, a partial 5-ht1a receptor agonist, administered systemically or into anterior cingulate attenuates repetitive behaviors in shank3b mice. 2021-09-21 2022-01-13 Not clear
Anes Ju, Beatriz Fernandez-Arroyo, Yifan Wu, D\\xc3\\xa9bora Jacky, Anna Beyele. Expression of serotonin 1A and 2A receptors in molecular- and projection-defined neurons of the mouse insular cortex. Molecular brain vol 13 issue 1 2021 32594910 the serotonin (5-ht) system is the target of multiple anxiolytics, including buspirone, which is a partial agonist of the serotonin 1a receptor (5-ht1a). 2021-07-08 2022-01-13 Not clear
Shawn Zheng Kai Tan, Yasin Temel, Ariel Yovela Chan, Andrea Tsz Ching Mok, Jose Angelo Udal Perucho, Arjan Blokland, Luca Aquili, Wei Ling Lim, Lee Wei Li. Serotonergic treatment normalizes midbrain dopaminergic neuron increase after periaqueductal gray stimulation. Brain structure & function vol 225 issue 7 2021 32594260 in this study, we further analysed our previous data on the effects of escitalopram (a selective serotonin reuptake inhibitor, ssri) and buspirone (a 5-ht1a receptor partial agonist) on dlpag-induced anticipatory fear behaviour in a rat model using freezing as a measure. 2021-07-06 2022-01-13 Not clear
Irina P Butkevich, Viktor A Mikhailenko, Elena A Vershinin. Neonatal pain modulates in adolescent rats the antinociceptive effects of fluoxetine and buspirone administrated to their depressive dams during gestation. Canadian journal of physiology and pharmacology vol 99 issue 6 2021 33186073 previously, we have shown that the administration of a selective serotonin reuptake inhibitor fluoxetine or a 5-ht1a receptor agonist buspirone to stressed rats during gestation causes in the offspring alleviation of formalin-induced pain, strengthened by prenatal stress. 2021-06-22 2022-01-13 Not clear
Xuefei Huang, Yaqi Kang, Xinrui Jiang, Jing Yang, An-Guo Wu, Chuanqing Zhang, Dalian Qin, Shousong Cao, Qibin Mei, Yun Ye, Jianming W. Tandospirone enhances the anti-myocardial fibrosis effect of valsartan in spontaneously hypertensive rats. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie vol 126 issue 2021 32179201 tandospirone, a partial agonist of the 5-ht1a receptor, has been commonly used to relieve psychiatric symptoms. 2021-01-26 2022-01-13 Not clear
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