| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tetsuya Takahashi, Hironori Mitsuya, Tetsuhito Murata, Junichi Murayama, Yuji Wad. Opposite effects of SSRIs and tandospirone in the treatment of REM sleep behavior disorder. Sleep medicine. vol 9. issue 3. 2008-08-29. PMID:17644482. |
we encountered a patient with idiopathic rbd that dramatically improved with selective serotonin reuptake inhibitors (ssris) and deteriorated with a 5-ht1a partial agonist, tandospirone. |
2008-08-29 |
2023-08-12 |
Not clear |
| Robert G K Munn, Neil McNaughto. Effects of fluoxetine on hippocampal rhythmic slow activity and behavioural inhibition. Behavioural pharmacology. vol 19. issue 3. 2008-07-15. PMID:18469543. |
groups of rats received, intraperitoneally, either (i) saline, or 5 mg/kg fluoxetine, or 10 mg/kg fluoxetine; or (ii) saline, or 20 mg/kg fluoxetine, or 6.6 mg/kg of the 5-ht1a agonist buspirone (bus) and were tested on a fixed interval 60-s schedule and a differential reinforcement of low rates 15-s schedule. |
2008-07-15 |
2023-08-12 |
rat |
| Hiroki Sato, Ivan Skelin, Guy Debonnel, Mirko Diksi. Chronic buspirone treatment normalizes open field behavior in olfactory bulbectomized rats: assessment with a quantitative autoradiographic evaluation of the 5-HT1A binding sites. Brain research bulletin. vol 75. issue 5. 2008-07-10. PMID:18355630. |
chronic buspirone treatment normalizes open field behavior in olfactory bulbectomized rats: assessment with a quantitative autoradiographic evaluation of the 5-ht1a binding sites. |
2008-07-10 |
2023-08-12 |
human |
| Jakob J Lopez, Mark Lorc. Location and orientation of serotonin receptor 1a agonists in model and complex lipid membranes. The Journal of biological chemistry. vol 283. issue 12. 2008-05-12. PMID:18187421. |
magic angle spinning (mas) nmr has been used to investigate the location and orientation of five serotonin receptor 1a agonists (serotonin, buspirone, quipazine, 8-oh-dpat, and ly-163,165) in single component model lipid and brain lipid membranes. |
2008-05-12 |
2023-08-12 |
Not clear |
| Tetsuya Takahashi, Tetsuhito Murata, Yuji Wad. Successful treatment of blepharospasm with tandospirone, a 5-HT1A partial agonist: a case report. Movement disorders : official journal of the Movement Disorder Society. vol 23. issue 1. 2008-04-14. PMID:17987656. |
successful treatment of blepharospasm with tandospirone, a 5-ht1a partial agonist: a case report. |
2008-04-14 |
2023-08-12 |
Not clear |
| C J Reissig, J R Eckler, R A Rabin, K C Rice, J C Winte. The stimulus effects of 8-OH-DPAT: evidence for a 5-HT2A receptor-mediated component. Pharmacology, biochemistry, and behavior. vol 88. issue 3. 2008-04-09. PMID:17936346. |
as shown previously, stimulus control by 8-oh-dpat and the generalization of 8-oh-dpat to the 5-ht1a partial agonist, buspirone, was completely blocked by the selective 5-ht1a antagonist, way-100635. |
2008-04-09 |
2023-08-12 |
rat |
| James W Crane, Keiko Shimizu, Gonzalo A Carrasco, Francisca Garcia, Cuihong Jia, Nicole R Sullivan, Deborah N D'Souza, Yahong Zhang, Louis D Van de Kar, Nancy A Muma, George Battagli. 5-HT1A receptors mediate (+)8-OH-DPAT-stimulation of extracellular signal-regulated kinase (MAP kinase) in vivo in rat hypothalamus: time dependence and regional differences. Brain research. vol 1183. 2008-03-25. PMID:17976547. |
we previously reported that systemic administration of either full or partial 5-ht1a agonists increases neuroendocrine responses and that tandospirone, an azapirone partial agonist, can activate (phosphorylate) extracellular signal-regulated kinase (erk) in the hypothalamic paraventricular nucleus (pvn). |
2008-03-25 |
2023-08-12 |
rat |
| R Hamish McAllister-Williams, Anna E Massey, Graeme Fairchil. Repeated cortisol administration attenuates the EEG response to buspirone in healthy volunteers: evidence for desensitization of the 5-HT1A autoreceptor. Journal of psychopharmacology (Oxford, England). vol 21. issue 8. 2008-01-29. PMID:17715208. |
repeated cortisol administration attenuates the eeg response to buspirone in healthy volunteers: evidence for desensitization of the 5-ht1a autoreceptor. |
2008-01-29 |
2023-08-12 |
human |
| Vincent J Aloyo, Kuldip D Dav. Behavioral response to emotional stress in rabbits: role of serotonin and serotonin2A receptors. Behavioural pharmacology. vol 18. issue 7. 2008-01-29. PMID:17912049. |
additionally, pretreatment with the 5-ht1a partial agonist and clinically used anxiolytic buspirone also significantly attenuated novelty-elicited head bobs. |
2008-01-29 |
2023-08-12 |
dog |
| Yukihiro Ohno, Hiroshi Hibino, Christoph Lossin, Atsushi Inanobe, Yoshihisa Kurach. Inhibition of astroglial Kir4.1 channels by selective serotonin reuptake inhibitors. Brain research. vol 1178. 2008-01-16. PMID:17920044. |
other ssris, sertraline and fluvoxamine, also inhibited kir4.1 channel currents whereas the tetracyclic (mianserin) or the 5-ht1a receptor-related (buspirone) antidepressants did not. |
2008-01-16 |
2023-08-12 |
Not clear |
| Tomiki Sumiyoshi, Sohee Park, Karu Jayathilake, Ajanta Roy, Aygun Ertugrul, Herbert Y Meltze. Effect of buspirone, a serotonin1A partial agonist, on cognitive function in schizophrenia: a randomized, double-blind, placebo-controlled study. Schizophrenia research. vol 95. issue 1-3. 2007-10-24. PMID:17628435. |
therefore, the goal of this randomly assigned placebo-controlled double-blind study was to determine if the addition of buspirone, a widely available 5-ht1a partial agonist, would enhance cognitive function, in subjects with schizophrenia treated with aapds. |
2007-10-24 |
2023-08-12 |
human |
| Aaron Ettenberg, Rick E Bernard. Effects of buspirone on the immediate positive and delayed negative properties of intravenous cocaine as measured in the conditioned place preference test. Pharmacology, biochemistry, and behavior. vol 87. issue 1. 2007-08-06. PMID:17524462. |
other groups of rats were treated identically except that 30-min prior to placement into the apparatus, these animals received an ip injection of saline or buspirone (a partial 5-ht1a agonist) at a dose that we have shown to be anxiolytic (2.5 mg/kg ip). |
2007-08-06 |
2023-08-12 |
rat |
| b' Ricard Navin\\xc3\\xa9s, Roc\\xc3\\xado Mart\\xc3\\xadn-Santos, Esther G\\xc3\\xb3mez-Gil, Mar\\xc3\\xada J Mart\\xc3\\xadnez de Osaba, M Luisa Imaz, Crist\\xc3\\xb3bal Gast\\xc3\\xb. Effects of citalopram treatment on hypothermic and hormonal responses to the 5-HT1A receptor agonist buspirone in patients with major depression and therapeutic response. Psychoneuroendocrinology. vol 32. issue 4. 2007-07-03. PMID:17337123.' |
effects of citalopram treatment on hypothermic and hormonal responses to the 5-ht1a receptor agonist buspirone in patients with major depression and therapeutic response. |
2007-07-03 |
2023-08-12 |
Not clear |
| b' Ricard Navin\\xc3\\xa9s, Roc\\xc3\\xado Mart\\xc3\\xadn-Santos, Esther G\\xc3\\xb3mez-Gil, Mar\\xc3\\xada J Mart\\xc3\\xadnez de Osaba, M Luisa Imaz, Crist\\xc3\\xb3bal Gast\\xc3\\xb. Effects of citalopram treatment on hypothermic and hormonal responses to the 5-HT1A receptor agonist buspirone in patients with major depression and therapeutic response. Psychoneuroendocrinology. vol 32. issue 4. 2007-07-03. PMID:17337123.' |
the hypothermic and endocrine responses (acth, cortisol, and prolactin) induced by the 5-ht1a receptor agonist, buspirone (30 mg p.o.) |
2007-07-03 |
2023-08-12 |
Not clear |
| Shinji Sato, Katsuyoshi Mizukami, Takashi Asad. A preliminary open-label study of 5-HT1A partial agonist tandospirone for behavioural and psychological symptoms associated with dementia. The international journal of neuropsychopharmacology. vol 10. issue 2. 2007-04-16. PMID:16817981. |
a preliminary open-label study of 5-ht1a partial agonist tandospirone for behavioural and psychological symptoms associated with dementia. |
2007-04-16 |
2023-08-12 |
Not clear |
| Shinji Sato, Katsuyoshi Mizukami, Takashi Asad. A preliminary open-label study of 5-HT1A partial agonist tandospirone for behavioural and psychological symptoms associated with dementia. The international journal of neuropsychopharmacology. vol 10. issue 2. 2007-04-16. PMID:16817981. |
the aim of this study was to assess the efficacy and safety of tandospirone, a 5-ht1a partial agonist, for treatment of behavioural and psychological symptoms of dementia (bpsd). |
2007-04-16 |
2023-08-12 |
Not clear |
| Kazuo Matsubara, Keiko Shimizu, Manabu Suno, Kento Ogawa, Toshio Awaya, Takehiro Yamada, Toshihiro Noda, Machiko Satomi, Ko-ichi Ohtaki, Kaoru Chiba, Yoshikazu Tasaki, Hiroshi Shion. Tandospirone, a 5-HT1A agonist, ameliorates movement disorder via non-dopaminergic systems in rats with unilateral 6-hydroxydopamine-generated lesions. Brain research. vol 1112. issue 1. 2006-11-28. PMID:16884702. |
tandospirone, a 5-ht1a agonist, ameliorates movement disorder via non-dopaminergic systems in rats with unilateral 6-hydroxydopamine-generated lesions. |
2006-11-28 |
2023-08-12 |
rat |
| Kazuo Matsubara, Keiko Shimizu, Manabu Suno, Kento Ogawa, Toshio Awaya, Takehiro Yamada, Toshihiro Noda, Machiko Satomi, Ko-ichi Ohtaki, Kaoru Chiba, Yoshikazu Tasaki, Hiroshi Shion. Tandospirone, a 5-HT1A agonist, ameliorates movement disorder via non-dopaminergic systems in rats with unilateral 6-hydroxydopamine-generated lesions. Brain research. vol 1112. issue 1. 2006-11-28. PMID:16884702. |
recent clinical studies suggest that tandospirone, a highly potent and selective 5-ht1a receptor agonist used clinically as an antidepressant in japan and china, may act as an antiparkinsonian drug. |
2006-11-28 |
2023-08-12 |
rat |
| Kazuo Matsubara, Keiko Shimizu, Manabu Suno, Kento Ogawa, Toshio Awaya, Takehiro Yamada, Toshihiro Noda, Machiko Satomi, Ko-ichi Ohtaki, Kaoru Chiba, Yoshikazu Tasaki, Hiroshi Shion. Tandospirone, a 5-HT1A agonist, ameliorates movement disorder via non-dopaminergic systems in rats with unilateral 6-hydroxydopamine-generated lesions. Brain research. vol 1112. issue 1. 2006-11-28. PMID:16884702. |
pretreatment with way-100635, a 5-ht1a receptor antagonist, almost completely blocked the contralateral turning behavior evoked by tandospirone and 8-ohdpat, but not that by apomorphine. |
2006-11-28 |
2023-08-12 |
rat |
| Kazuo Matsubara, Keiko Shimizu, Manabu Suno, Kento Ogawa, Toshio Awaya, Takehiro Yamada, Toshihiro Noda, Machiko Satomi, Ko-ichi Ohtaki, Kaoru Chiba, Yoshikazu Tasaki, Hiroshi Shion. Tandospirone, a 5-HT1A agonist, ameliorates movement disorder via non-dopaminergic systems in rats with unilateral 6-hydroxydopamine-generated lesions. Brain research. vol 1112. issue 1. 2006-11-28. PMID:16884702. |
these results suggested that tandospirone could act on postsynaptic 5-ht1a receptors and modulate excitatory amino acid pathways in the basal ganglia. |
2006-11-28 |
2023-08-12 |
rat |