All Relations between 5-ht receptor 1a and Azapirones

Publication Sentence Publish Date Extraction Date Species
C A Chessick, M H Allen, Me Thase, A B C Batista Miralha da Cunha, F F K Kapczinski, M S M L de Lima, J J S S dos Santos Souz. Azapirones for generalized anxiety disorder. The Cochrane database of systematic reviews. issue 3. 2006-10-16. PMID:16856115. azapirones are a group of drugs that work at the 5-ht1a receptor and are used to treat patients suffering from generalized anxiety disorder (gad). 2006-10-16 2023-08-12 Not clear
A C E Linthors. Interactions between corticotropin-releasing hormone and serotonin: implications for the aetiology and treatment of anxiety disorders. Handbook of experimental pharmacology. issue 169. 2006-06-13. PMID:16594259. although the picture is far from complete yet--partly due to the large number of serotonin (5-ht) receptors and the often-disparate effects of receptor agonists and antagonists in animal models of anxiety--ssris and the 5-ht1a agonist buspirone have now earned their place in the treatment of anxiety disorders. 2006-06-13 2023-08-12 Not clear
Arata Watanabe, Shu Hasegawa, Kyoko Nishi, Khnah Q Nguyen, Mirko Diksi. Chronic buspirone treatment normalizes regional serotonin synthesis in the olfactory bulbectomized rat brain: an autoradiographic study. Brain research bulletin. vol 69. issue 2. 2006-06-01. PMID:16533657. these results suggest that normalization (reduction to the level found in the shx-sal rats) of 5-ht synthesis in the obx requires a greater dose of buspirone (20 mg/(kg day)) than that needed to produce a desensitization of the 5-ht1a receptors in the sham operated rats (10 mg/(kg day)). 2006-06-01 2023-08-12 rat
Andrea Gogos, Pradeep J Nathan, Valérie Guille, Rodney J Croft, Maarten van den Buus. Estrogen prevents 5-HT1A receptor-induced disruptions of prepulse inhibition in healthy women. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 31. issue 4. 2006-05-25. PMID:16237386. this study examined the effects of estrogen treatment on modulation of prepulse inhibition (ppi) by the serotonin-1a (5-ht1a) receptor partial agonist, buspirone. 2006-05-25 2023-08-12 Not clear
Howard Choi, Wei-Lee Liao, Kimberly M Newton, Renna C Onario, Allyson M King, Federico C Desilets, Eric J Woodard, Marc E Eichler, Walter R Frontera, Sunil Sabharwal, Yang D Ten. Respiratory abnormalities resulting from midcervical spinal cord injury and their reversal by serotonin 1A agonists in conscious rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 18. 2006-03-23. PMID:15872102. treatment with another 5-ht1a receptor agonist, buspirone (1.5 mg/kg, i.p. 2006-03-23 2023-08-12 human
Sue J Wilson, Jayne E Bailey, Ann S Rich, Jon Nash, Mariona Adrover, A Tournoux, David J Nut. The use of sleep measures to compare a new 5HT1A agonist with buspirone in humans. Journal of psychopharmacology (Oxford, England). vol 19. issue 6. 2006-02-09. PMID:16272182. the use of sleep measures to compare a new 5ht1a agonist with buspirone in humans. 2006-02-09 2023-08-12 human
Mary Druse, Nuzhath F Tajuddin, Roberta A Gillespie, Phong L. Signaling pathways involved with serotonin1A agonist-mediated neuroprotection against ethanol-induced apoptosis of fetal rhombencephalic neurons. Brain research. Developmental brain research. vol 159. issue 1. 2006-02-03. PMID:16081165. apoptotic and non-apoptotic fetal rhombencephalic neurons were quantitated in primary cultures that were treated with 50 mm ethanol and with 100 nm of a 5-ht1a agonist such as 8-oh-dpat [8-hydroxy 2-(di-n-propylamino)tetralin], ipsapirone, or buspirone. 2006-02-03 2023-08-12 Not clear
Valquíria Camin de Bortoli, Regina Lúcia Nogueira, Hélio Zangross. Effects of fluoxetine and buspirone on the panicolytic-like response induced by the activation of 5-HT1A and 5-HT2A receptors in the rat dorsal periaqueductal gray. Psychopharmacology. vol 183. issue 4. 2006-01-31. PMID:16258751. effects of fluoxetine and buspirone on the panicolytic-like response induced by the activation of 5-ht1a and 5-ht2a receptors in the rat dorsal periaqueductal gray. 2006-01-31 2023-08-12 rat
David H Overstreet, Darin J Knapp, George R Brees. Pharmacological modulation of repeated ethanol withdrawal-induced anxiety-like behavior differs in alcohol-preferring P and Sprague-Dawley rats. Pharmacology, biochemistry, and behavior. vol 81. issue 1. 2005-12-30. PMID:15894069. a small study showed that buspirone, a 5-ht1a agonist, also had prophylactic effects in p rats. 2005-12-30 2023-08-12 rat
Soon-Tae Lee, Jong-Ha Park, Manho Ki. Efficacy of the 5-HT1A agonist, buspirone hydrochloride, in migraineurs with anxiety: a randomized, prospective, parallel group, double-blind, placebo-controlled study. Headache. vol 45. issue 8. 2005-12-20. PMID:16109114. efficacy of the 5-ht1a agonist, buspirone hydrochloride, in migraineurs with anxiety: a randomized, prospective, parallel group, double-blind, placebo-controlled study. 2005-12-20 2023-08-12 Not clear
Soon-Tae Lee, Jong-Ha Park, Manho Ki. Efficacy of the 5-HT1A agonist, buspirone hydrochloride, in migraineurs with anxiety: a randomized, prospective, parallel group, double-blind, placebo-controlled study. Headache. vol 45. issue 8. 2005-12-20. PMID:16109114. to examine the efficacy of buspirone, a 5-ht1a agonist, for migraine combined with anxiety disorder. 2005-12-20 2023-08-12 Not clear
Asako Takei, Takeshi Hamada, Ichiro Yabe, Hidenao Sasak. Treatment of cerebellar ataxia with 5-HT1A agonist. Cerebellum (London, England). vol 4. issue 3. 2005-11-08. PMID:16147954. we recently reported preliminary evidence that tandospirone citrate (tandospirone), a 5-ht1a agonist, improved cerebellar ataxia in patients with machado-joseph disease (mjd). 2005-11-08 2023-08-12 Not clear
R L Djavadian, E Wielkopolska, K Turlejsk. Postnatal treatment with NAN-190 but not with 5-HT1A receptor agonists retards growth of the rat brain. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 23. issue 5. 2005-09-26. PMID:16026684. we investigated the influence of prolonged administration of the 5-ht1a receptor agonists (8-oh-dpat or buspirone) or its antagonist, nan-190 to rat pups on development of their cortical barrel field. 2005-09-26 2023-08-12 rat
C Moret, M Brile. Where are the new therapies for anxiety and obsessive-compulsive disorders? IDrugs : the investigational drugs journal. vol 4. issue 9. 2005-08-23. PMID:15965850. the 5-ht1a partial agonist, buspirone (bristol-myers-squibb), is one of the few compounds developed principally as an anxiolytic since the benzodiazepines. 2005-08-23 2023-08-12 Not clear
Maria H Paluchowska, Ryszard Bugno, Andrzej J Bojarski, Sijka Charakchieva-Minol, Beata Duszyńska, Ewa Tatarczyńska, Aleksandra Kłodzińska, Katarzyna Stachowicz, Ewa Chojnacka-Wójci. Novel, flexible, and conformationally defined analogs of gepirone: synthesis and 5-HT1A, 5-HT2A, and D2 receptor activity. Bioorganic & medicinal chemistry. vol 13. issue 4. 2005-08-02. PMID:15670928. novel, flexible, and conformationally defined analogs of gepirone: synthesis and 5-ht1a, 5-ht2a, and d2 receptor activity. 2005-08-02 2023-08-12 Not clear
Maria H Paluchowska, Ryszard Bugno, Andrzej J Bojarski, Sijka Charakchieva-Minol, Beata Duszyńska, Ewa Tatarczyńska, Aleksandra Kłodzińska, Katarzyna Stachowicz, Ewa Chojnacka-Wójci. Novel, flexible, and conformationally defined analogs of gepirone: synthesis and 5-HT1A, 5-HT2A, and D2 receptor activity. Bioorganic & medicinal chemistry. vol 13. issue 4. 2005-08-02. PMID:15670928. novel, flexible arylpiperazine gepirone analogs (1a-3a) with a mixed 5-ht1a/5-ht2a receptor profile, low d2 receptor affinity, and agonistic (2a) or partial agonistic (1a, 3a) activity toward 5-ht1a receptor sites were synthesized. 2005-08-02 2023-08-12 Not clear
Maarten van den Buuse, Nico Wegene. Involvement of serotonin1A receptors in cardiovascular responses to stress: a radio-telemetry study in four rat strains. European journal of pharmacology. vol 507. issue 1-3. 2005-07-25. PMID:15659309. we studied the effect of treatment with the serotonin-1a (5-ht1a) receptor ligands buspirone, 8-hydroxy-di-propyl-aminotetralin (8-oh-dpat), and (8-[2-(2,3-dihydro-1,4-benzodioxin-2-yl-methylamino)ethyl]-8-azaspiro[4,5]decane-7,9-dione methyl sulphonate (mdl73,005ef) on blood pressure and heart rate increases to open field stress. 2005-07-25 2023-08-12 rat
G K Pal, N Kannan, Pravati Pa. Effects of injection of serotonin into nucleus caudatus on food and water intake and body weight in albino rats. Indian journal of physiology and pharmacology. vol 48. issue 4. 2005-07-22. PMID:15907052. in the present study, serotonin hydrochloride, buspirone (the serotonin 5-ht1a agonist) and ondensetron (the 5ht3 antagonist) were injected into nucleus caudatus through stereotaxically implanted cannulae in three different dosages (1, 2 and 5 microg) and their effects on 24 h food and water intake, and body weight were recorded. 2005-07-22 2023-08-12 rat
Briones-Aranda Alfredo, Picazo Ofi. Effect of the postsynaptic 5-HT1A receptor antagonist MM-77 on stressed mice treated with 5-HT1A receptor agents. European journal of pharmacology. vol 508. issue 1-3. 2005-07-14. PMID:15680266. the pharmacological effect of the 5-ht1a receptor ligands, 8-hydroxy-2-(di-n-propylamino)tetralin (8-oh-dpat), indorenate, and buspirone, alone or in combination with the antagonist mm-77, was studied in mice subjected to forced swimming. 2005-07-14 2023-08-12 mouse
Nicole R Sullivan, James W Crane, Katerina J Damjanoska, Gonzalo A Carrasco, Deborah N D'Souza, Francisca Garcia, Louis D Van de Ka. Tandospirone activates neuroendocrine and ERK (MAP kinase) signaling pathways specifically through 5-HT1A receptor mechanisms in vivo. Naunyn-Schmiedeberg's archives of pharmacology. vol 371. issue 1. 2005-07-11. PMID:15655673. tandospirone activates neuroendocrine and erk (map kinase) signaling pathways specifically through 5-ht1a receptor mechanisms in vivo. 2005-07-11 2023-08-12 rat